Tay-Sachs Disease - Causes

Every child receives two sets of genes, one from its mother and one from its father. These genes may be either dominant or recessive. A dominant gene is "stronger" than a recessive gene and controls the way a cell is going to function.

If a recessive gene is paired with a dominant gene, the recessive gene has no effect on the way a cell functions. The dominant gene overcomes the recessive gene. The only way a recessive gene has any effect on a cell if it is paired with another recessive gene. In such cases, the two recessive genes work together to direct a cell's operation.

Tay-Sachs is caused by a recessive gene. A child with one recessive gene shows no effect as a result of having the gene. The child is a carrier for the disease. A carrier is a person who has one recessive gene for a characteristic. The carrier can pass the gene on to his or her children even though the carrier does not have the disease.

A child with a pair of these recessive genes, however, will show the symptoms of Tay-Sachs disease because the child will lack a normal gene to makes the enzyme needed to break down gangliosides.