Again, like many things on the net, the answer to all of these
    questions is: "Yes, but it depends."

    A moderated *discussion* group that expects fast (< 1 hour)
    turn-around for messages will have requirements different from
    moderated announcement groups that generally have no need for
    turnaround faster than 24-48 hours.

    At least one (low-volume) group is moderated from a laptop,
    under MS-Windows, with e-mail software downloaded from the net.

    Most moderators probably operate from a Unix host,
    but there is no requirement that they do so.

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