Thalidomide exists as two enantiomers. The 'R' isomer is an...

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Question by chemkid
Submitted on 9/26/2003
Related FAQ: Sci.chem FAQ - Part 1 of 7
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Thalidomide exists as two enantiomers. The 'R' isomer is an antidepressant and the 'S' isomer has been linked to severe birth defects. Why do the isomers of thalidomide have different biological activites?

Answer by binh_thanh92@yahoo.com
Submitted on 12/12/2003
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that is a simple problem. I will give you an example. you can write a text easily if you write it as you do everyday, but if you write it as the text you see in a mirror, that will be impossible. the power of differentiation of enzymes in cells are very limited, so it can only act on selected substrate. the difference is as important as the letter p and q or ( and ), b and d. PS: pig and big and dig are 3 diastereomers

Answer by huxey
Submitted on 3/22/2004
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what the the full names of the S & R enantiomers?

Answer by b0JZQ8rxL0
Submitted on 2/26/2006
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Pkj7fllOFk4 4sbLCHc4qlY8 LNZEdWt2KByiDT

Answer by Dave
Submitted on 10/5/2006
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S 2-(2,6-dioxo-3-piperidyl)isoindole-1,3-dione and R 2-(2,6-dioxo-3-piperidyl)isoindole-1,3-dione. These obviously have the same structural formula, but will cause plane polarised light to be refracted differently.

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