Zhao, MD
Aiping Zhao, Ellicott City, MD US
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20140037578 | IL-25 Treatment of Obesity and Metabolic Disorders - The present invention provides a method for reducing the weight of a subject, preventing weight gain in a subject, lowering blood glucose, or treating hepatic steatosis, comprising administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising interleukin-25 or IL-25-activated macrophages. In addition, the present invention provides a method of treating cachexia or promoting weight gain in a mammal in need of such treatment, comprising administering to the mammal a therapeutically effective amount of a pharmaceutical composition comprising an inhibitor or antagonist of interleukin-25 in a mammal in the treatment of cachexia. | 02-06-2014 |
Chao Zhao, Rockville, MD US
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20150218617 | CYCLOPENTANE-PEPTIDE NUCLEIC ACIDS FOR QUALITATIVE AND QUANTITATIVE DETECTION OF NUCLEIC ACIDS - The invention concerns methods for detecting a nucleic acid of interest in a solution comprising (a) contacting a solution suspected of containing the nucleic acid of interest with a PNA capture probe and a PNA reporter probe; wherein (i) the PNA capture probe comprises at least two trans-cyclopentanes; (ii) the PNA reporter probe comprises at least six biotin groups; (iii) the PNA capture probe bound to a surface; and (iv) the PNA capture probe and the PNA reporter probe each comprise a nucleobase sequence that is complementary to different non-overlapping portions of the nucleic acid of interest; (b) detecting the presence of the PNA capture probe and the PNA reporter probe bound to the surface; wherein the nucleic acid of interest is detected when 1-1000 molecules of the nucleic acid of interest are present in the solution being tested. | 08-06-2015 |
Chunling Zhao, Laurel, MD US
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20080251601 | WATER SENSOR APPARATUS - A water sensor apparatus used in connection with a watering system. The water sensor apparatus includes a main housing comprising an inlet and an outlet. A valve mechanism is provided inside the main housing. The valve mechanism opens and closes the outlet of the main housing in response to a water level collected in the main housing and a water pressure entering the inlet of the main housing. | 10-16-2008 |
20090324434 | WASHER PUMP - An enhanced pump assembly includes an impeller and volute casing designed to provide high operating pressures (āPā) and flow rates (āQā) with low energy usage. The impeller has a central shaft carrying radially projecting curved primary vanes, and each primary vane also has a twist in the radial direction. Secondary impeller vanes define triangular connecting fillet-like wall segments connecting each primary vane to the impeller shaft. The casing of the pump has a slight spiral deviation so that the pump chamber's radial sidewall flares away from the swept area of the impeller's vanes to define a fluid outlet that contributes to higher P-Q performance, especially when pumping colder fluids. | 12-31-2009 |
20110089250 | Irrigation Spray Nozzles for Rectangular Patterns - An inexpensive, durable and efficient irrigation nozzle assembly is adapted to generate a specialized rectangular spray in a 3-jet fluidic circuit which generates a substantially planar rectangular spray from a confluence of three jets. The 3-jet geometry circuit has selected floor & taper features configured to create a customizable rectangular or triangular spray pattern. Depending on the throw desired, the nozzle assembly of the present invention can be configured with a second fluidic circuit to generate a flat fan to obtain various aspect ratios in a rectangular spray. | 04-21-2011 |
20130045095 | WASHER PUMP - An improved automotive pump assembly includes a volute pumping chamber configured to operably contain a rotatable impeller which, when driven, draws fluid into a fluid inlet and pumps the fluid to and through a fluid outlet. The volute chamber has an exterior sidewall with a constant internal first radius over a first sidewall portion and transitions to a second sidewall portion of increasing radius. The chamber's second sidewall portion defines a first end at a sidewall transition point tangent to the constant radius sidewall segment to define a second end which is tangent to the volute chamber's fluid outlet with a second radius that is greater than the first radius. | 02-21-2013 |
Jiangang Zhao, Baltimore, MD US
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20080257328 | Tile saw - A tile saw includes a base, a frame assembly disposed on the base, a first rail disposed on the frame assembly, the first rail having a longitudinal axis, a table slidingly disposed on the first rail, a support assembly disposed on the base, a saw assembly supported by the support assembly, the saw assembly comprising a motor, a cutting wheel driven by the motor, the saw assembly being pivotable about a horizontal axis substantially parallel to the longitudinal axis, and a switch electrically connected to the motor and disposed on the support assembly so that, when the motor assembly is pivoted about the horizontal axis, the switch remains stationary. | 10-23-2008 |
20110018377 | ELECTRIC MOTORS HAVING EMI REDUCING CIRCUITS AND METHODS THEREFOR - An electric motor having a circuit for reducing electromagnetic interference (EMI) includes a field stack such as a stator, an armature including a shaft, a commutator mounted on the shaft, and an armature core electrically connected to the commutator, whereby the armature core is rotatably mounted within the field stack. The electric motor includes a brush assembly adapted to deliver electrical power to the commutator. The circuit includes a delta capacitor network and a conductive lead electrically interconnecting the delta capacitor network and the brush assembly. In one embodiment, the circuit includes motor field windings or coils, and a power source electrically interconnectable with the delta capacitor network and the motor field windings. In one embodiment, the motor is a universal motor. | 01-27-2011 |
20110226110 | Tile Saw - A tile saw includes a base, a frame assembly disposed on the base, a first rail disposed on the frame assembly, the first rail having a longitudinal axis, a table slidingly disposed on the first rail, a support assembly disposed on the base, a saw assembly supported by the support assembly, the saw assembly comprising a motor, a cutting wheel driven by the motor, the saw assembly being pivotable about a horizontal axis substantially parallel to the longitudinal axis, and a switch electrically connected to the motor and disposed on the support assembly so that, when the motor assembly is pivoted about the horizontal axis, the switch remains stationary. | 09-22-2011 |
20110271945 | TILE SAW - A tile saw includes a base, a frame assembly disposed on the base, a first rail disposed on the frame assembly, the first rail having a longitudinal axis, a table slidingly disposed on the first rail, a support assembly disposed on the base, a saw assembly supported by the support assembly, the saw assembly comprising a motor, a cutting wheel driven by the motor, the saw assembly being pivotable about a horizontal axis substantially parallel to the longitudinal axis, and a switch electrically connected to the motor and disposed on the support assembly so that, when the motor assembly is pivoted about the horizontal axis, the switch remains stationary. | 11-10-2011 |
20130055865 | Tile Saw - A tile saw includes a base, a frame assembly disposed on the base, a first rail disposed on the frame assembly, the first rail having a longitudinal axis, a table slidingly disposed on the first rail, a support assembly disposed on the base, a saw assembly supported by the support assembly, the saw assembly comprising a motor, a cutting wheel driven by the motor, the saw assembly being pivotable about a horizontal axis substantially parallel to the longitudinal axis, and a switch electrically connected to the motor and disposed on the support assembly so that, when the motor assembly is pivoted about the horizontal axis, the switch remains stationary. | 03-07-2013 |
20130055866 | Tile Saw - A tile saw includes a base, a frame assembly disposed on the base, a first rail disposed on the frame assembly, the first rail having a longitudinal axis, a table slidingly disposed on the first rail, a support assembly disposed on the base, a saw assembly supported by the support assembly, the saw assembly comprising a motor, a cutting wheel driven by the motor, the saw assembly being pivotable about a horizontal axis substantially parallel to the longitudinal axis, and a switch electrically connected to the motor and disposed on the support assembly so that, when the motor assembly is pivoted about the horizontal axis, the switch remains stationary. | 03-07-2013 |
20130055867 | Tile Saw - A tile saw includes a base, a frame assembly disposed on the base, a first rail disposed on the frame assembly, the first rail having a longitudinal axis, a table slidingly disposed on the first rail, a support assembly disposed on the base, a saw assembly supported by the support assembly, the saw assembly comprising a motor, a cutting wheel driven by the motor, the saw assembly being pivotable about a horizontal axis substantially parallel to the longitudinal axis, and a switch electrically connected to the motor and disposed on the support assembly so that, when the motor assembly is pivoted about the horizontal axis, the switch remains stationary. | 03-07-2013 |
20130055869 | Tile Saw - A tile saw includes a base, a frame assembly disposed on the base, a first rail disposed on the frame assembly, the first rail having a longitudinal axis, a table slidingly disposed on the first rail, a support assembly disposed on the base, a saw assembly supported by the support assembly, the saw assembly comprising a motor, a cutting wheel driven by the motor, the saw assembly being pivotable about a horizontal axis substantially parallel to the longitudinal axis, and a switch electrically connected to the motor and disposed on the support assembly so that, when the motor assembly is pivoted about the horizontal axis, the switch remains stationary. | 03-07-2013 |
20130055870 | Tile Saw - A tile saw includes a base, a frame assembly disposed on the base, a first rail disposed on the frame assembly, the first rail having a longitudinal axis, a table slidingly disposed on the first rail, a support assembly disposed on the base, a saw assembly supported by the support assembly, the saw assembly comprising a motor, a cutting wheel driven by the motor, the saw assembly being pivotable about a horizontal axis substantially parallel to the longitudinal axis, and a switch electrically connected to the motor and disposed on the support assembly so that, when the motor assembly is pivoted about the horizontal axis, the switch remains stationary. | 03-07-2013 |
20130055871 | Tile Saw - A tile saw includes a base, a frame assembly disposed on the base, a first rail disposed on the frame assembly, the first rail having a longitudinal axis, a table slidingly disposed on the first rail, a support assembly disposed on the base, a saw assembly supported by the support assembly, the saw assembly comprising a motor, a cutting wheel driven by the motor, the saw assembly being pivotable about a horizontal axis substantially parallel to the longitudinal axis, and a switch electrically connected to the motor and disposed on the support assembly so that, when the motor assembly is pivoted about the horizontal axis, the switch remains stationary. | 03-07-2013 |
Mingtao Zhao, Baltimore, MD US
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20140039261 | OPTICAL COHERENCE TOMOGRAPHY SYSTEM AND METHOD FOR REAL-TIME SURGICAL GUIDANCE - An optical coherence tomography (OCT) system for real-time surgical guidance includes an optical source, an optical fiber configured to be optically coupled to the optical source, a plurality of OCT sensor heads configured to be optically coupled to the optical fiber, an optical detector configured to be optically coupled to the optical fiber, a signal processor configured to communicate with the optical detector to receive detected signals therefrom, and a display system configured to receive OCT image signals from the signal processor and to display an OCT image of at least a portion of a surgical region of interest in real time to provide surgical guidance. The plurality of OCT sensor heads includes a bulk sensor head configured to image at least a portion of the surgical region of interest from an external imaging position and an endoscopic sensor head configured to be inserted into the surgical region of interest to image at least a portion of the surgical region of interest from an internal imaging position. The bulk sensor head and the endoscopic sensor head are at least one of separate exchangeable sensor heads or a reconfigurable sensor head. | 02-06-2014 |
20140160486 | SAPPHIRE LENS-BASED OPTICAL FIBER PROBE FOR OPTICAL COHERENCE TOMOGRAPHY - A probe for an optical coherence tomography system according to an embodiment of the current invention includes a sheath having a proximal end and a distal end and defining a lumen therein, an optical fiber disposed at least partially within the lumen of said sheath, and a sapphire lens attached to the distal end of the sheath to form a fluid-tight seal to prevent fluid from entering the lumen of said sheath. The optical fiber has an end arranged in an optical path with the sapphire lens to provide optical coupling between the sapphire lens and the optical fiber. | 06-12-2014 |
Peter Zhao, Baltimore, MD US
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20090206783 | Soft start for electric motor of a power tool - A power tool has an electric motor with field windings. In an aspect of the invention, each field winding includes two coils wound with the same number of turns of the same gauge magnet wire. When the motor is first energized, the two coils of each field winding are connected in series, reducing in-rush current. Upon expiration of a soft start period, which can be after the motor reaches a predetermined speed or upon expiration of a predetermined time period, the two coils of each field winding are connected in parallel. In another aspect of the invention, an electric motor used in a power tool includes field windings that are connected in series with a separate start winding when the motor is first energized. Upon expiration of the soft start period, the start winding is bypassed. In another aspect of the invention, the separate start winding includes two sub-windings. The two sub-windings are connected in a way that magnetic field created by the two sub-windings is counterbalanced so that the overall magnetic force created by the start winding in the motor armature is minimized or zero. Also, the voltage across the two sub-windings is minimized or zero. In another aspect, the field windings are connected in series with a start impedance when the motor is first energized and a time delay relay having a set of delay contacts coupled across the start impedance energized. Upon expiration of the soft start period, the time delay contacts close, bypassing the start impedance. In an aspect, the motor is a universal motor. | 08-20-2009 |
Qi Zhao, Frederick, MD US
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20140044720 | HUMAN MONOCLONAL ANTIBODIES THAT BIND INSULIN-LIKE GROWTH FACTOR (IGF) I AND II - Disclosed herein are human monoclonal antibodies that specifically bind both IGF-I and IGF-II with picomolar affinity and potently inhibit the IGF-IR signal transduction function. These antibodies are active in both an IgG and a scFv format. Bispecific forms of these antibodies are also disclosed. Nucleic acids encoding these antibodies, vectors including these nucleic acids, and host cells transformed with these vectors are also disclosed herein. Also disclosed are pharmaceutical compositions including these antibodies. Methods are provided for treating a subject with cancer and for inhibiting phosphorylation of the insulin-like growth factor-I receptor. Methods are also provided for diagnosing cancer. | 02-13-2014 |
20160024199 | HUMAN MONOCLONAL ANTIBODIES THAT BIND INSULIN-LIKE GROWTH FACTOR (IGF) I AND II - Disclosed herein are human monoclonal antibodies that specifically bind both IGF-I and IGF-II with picomolar affinity and potently inhibit the IGF-IR signal transduction function. These antibodies are active in both an IgG and a scFv format. Bispecific forms of these antibodies are also disclosed. Nucleic acids encoding these antibodies, vectors including these nucleic acids, and host cells transformed with these vectors are also disclosed herein. Also disclosed are pharmaceutical compositions including these antibodies. Methods are provided for treating a subject with cancer and for inhibiting phosphorylation of the insulin-like growth factor-I receptor. Methods are also provided for diagnosing cancer. | 01-28-2016 |
Qinghai Zhao, North Potomac, MD US
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20140199283 | FORMULATIONS OF ALBU-BCHE, PREPARATION AND USES THEREOF - The present invention provides an aqueous pharmaceutical composition comprising the fusion protein whose amino acid sequence is set forth as SEQ ID No:1 and an aqueous solution comprising 40 to 60 mM sodium phosphate. The present invention further provides a lyophilized pharmaceutical composition, an reconstituted solution, a sealed package comprising the lyophilized pharmaceutical composition, and a vial comprising the lyophilized pharmaceutical or the reconstituted solution. The present invention also provides a method of producing the lyophilized pharmaceutical composition and the sealed package. The present invention also provides a method of treating a human having cocaine seeking behavior, and methods of using the aqueous pharmaceutical composition and lyophilized pharmaceutical composition. | 07-17-2014 |
20140199286 | LYOPHILIZATION PROCESS - The present invention provides a process for producing a lyophilized pharmaceutical composition containing a protein. The present invention further provides a product produced by the process. The present invention further provides a process for producing an injectable pharmaceutical composition. The present invention further provides a method of treating a patient with a therapeutic protein composition. | 07-17-2014 |
Richard Y. Zhao, Brookeville, MD US
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20090172828 | BYDV MP IS A VIRAL DETERMINANT RESPONSIBLE FOR PLANT GROWTH RETARDATION - The present invention concerns the barley yellow dwarf virus (BYDV) and compositions and methods related thereto. In particular in the invention, identifies a movement protein (MP) of BYDV as being responsible for at least one symptom produced as a result of BYDV infection. In certain aspects, the invention concerns a target to inhibit BYDV and to inhibit at least one symptom of BYDV infection, for example, at least plant growth retardation. In particular aspects, the invention relates to screening methods for identifying suppressors of BYDV MP. | 07-02-2009 |
Wei-Qin Zhao, Germantown, MD US
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20100278803 | Alzheimer's Disease Diagnosis Based on Mitogen-Activated Protein Kinase Phosphorylation - A method of diagnosing Alzheimer's disease in a patient comprises determining whether the phosphorylation level of an indicator protein in cells of the patient after stimulus with an activator compound is abnormally elevated as compared to a basal phosphorylation level, the indicator protein being e.g. Erk1/2 and the activator compound being e.g. bradykinin. | 11-04-2010 |
Xinjin Zhao, Woodbine, MD US
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20090068079 | Compositions and processes for reducing NOx emissions during fluid catalytic cracking - Compositions for reduction of NO | 03-12-2009 |
20100276337 | FERRIERITE COMPOSITION FOR REDUCING NOX EMISSIONS DURING FLUID CATALYTIC CRACKING - Compositions for reduction of NO | 11-04-2010 |
Xiongce Zhao, Gaithersburg, MD US
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20110031389 | System and Method for Trapping and Measuring a Charged Particle in a Liquid - A system and method for trapping a charged particle is disclosed. A time-varying periodic multipole electric potential is generated in a trapping volume. A charged particle under the influence of the multipole electric field is confined to the trapping volume. A three electrode configuration giving rise to a 3D Paul trap and a four planar electrode configuration giving rise to a 2D Paul trap are disclosed. | 02-10-2011 |
20130026387 | SYSTEM AND METHOD FOR TRAPPING AND MEASURING A CHARGED PARTICLE IN A LIQUID - A system and method for trapping a charged particle is disclosed. A time-varying periodic multipole electric potential is generated in a trapping volume. A charged particle under the influence of the multipole electric field is confined to the trapping volume. A three electrode configuration giving rise to a 3D Paul trap and a four planar electrode configuration giving rise to a 2D Paul trap are disclosed. | 01-31-2013 |
Xue Zhi Zhao, Frederick, MD US
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20160083382 | COMPOUNDS FOR INHIBITING DRUG-RESISTANT STRAINS OF HIV-1 INTEGRASE - A method of inhibiting drug-resistant HIV-1 integrase in a subject comprising administering to a subject in need thereof a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt or ester thereof, having a structure of: | 03-24-2016 |
Yinyan Zhao, Rockville, MD US
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20120114739 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS - The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds. | 05-10-2012 |
Yonghong Zhao, North Potomac, MD US
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20100028010 | Method and system for updating a control device database via flashing light - A system for delivering codes to a remote control for controlling a number of electronic devices includes a receiver for receiving a signal from a transmitter. A display connected to the receiver has a mechanism for flashing visible-light to the remote control, the flashed visible-light being related to the signal. The remote control includes a code database and mechanisms for receiving flashed visible-light and converting it into a code storable in the database. A method for acquiring updated codes includes storing codes for controlled apparatus in a code database. Data related to additional device codes are then transmitted to a processing device connected to a visual display. The data are flashed as visible-light from the display and received by the remote control. Received visible-light is converted into at least one device code and used to update the code database in the remote control. | 02-04-2010 |
Zhiyong Zhao, Ellicott City, MD US
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20100291069 | METHODS OF TREATING A DIABETIC EMBRYOPATHY - Maternal diabetes can lead to a developmental malformation of an embryo. A developmental malformation caused by maternal diabetes is commonly referred to as a diabetic embryopathy. There is currently no effective treatment for reducing or inhibiting a diabetic embryopathy. To this end, the present invention is drawn to novel methods of treating a diabetic embryopathy. | 11-18-2010 |
Zhong Zhao, Ellicott City, MD US
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20090247778 | Phosphorus-Containing Compounds with Polymeric Chains, and Methods of Making and Using the Same - The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation. | 10-01-2009 |
20100267924 | Phosphorus-Containing Compounds with Polymeric Chains, and Methods of Making and Using the Same - The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation. | 10-21-2010 |
20130023688 | PHOSPHORUS-CONTAINING COMPOUNDS WITH POLYMERIC CHAINS, AND METHODS OF MAKING AND USING THE SAME - The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation. | 01-24-2013 |