Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Zhang, PA
Benyuan Zhang, Drexel Hill, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080317182 | Method and Apparatus for Multiresolution / Multipath Searcher - A multipath searcher and method includes a programmable decimation filter configured to adjust a sample rate of a received pilot signal. A plurality of correlators is configured to compare the received pilot signal to a reference code in a first mode and in a second mode. The first mode includes a low resolution search of a search window performed such that the plurality of correlators encompass an entire search window concurrently and the plurality of correlators receives a delayed reference code delayed to correspond with a portion of the search window in which a corresponding correlator performs correlation to identify peaks in the received pilot signal. The second mode includes a high resolution search of a refined search window only at or near identified peaks discovered in the first mode. The high resolution search is focused at the peak location by adjusting delays in the plurality of correlators. | 12-25-2008 |
| 20100067564 | Time Multiplexed Non-Coherent Multipath Search Method and Apparatus - An apparatus for performing a multipath search including a plurality of time-multiplexed chip correlators, wherein each of the plurality of time-multiplexed chip correlators has a pipeline, and further wherein each of the plurality of time-multiplexed chip correlators has a accumulation time is described. A method is described for performing a multipath search including performing multipath search slot processing, determining if a current multipath searching slot is a last multipath searching slot, if the current multipath searching slot is not the last multipath searching slot, then repeating the performing step, if the current multipath searching slot is the last multipath searching slot, then initializing a multipath searching slot index, determining if an non-coherent accumulation has been completed if the accumulation has not been completed then repeating all steps and if the accumulation has been completed, then search results are sorted to locate energy peaks corresponding to multipath locations. | 03-18-2010 |
| 20100220603 | Multipath Searcher Results Sorting Method - A method and apparatus for identifying valid multipath energy peaks are described including locating an energy peak in a profile of energy peaks, categorizing the located energy peak based on a plurality of thresholds and processing energy peaks in at least one of the categories of located energy peaks. The method and apparatus further includes removing a direct current value component from each value in the profile of energy peaks, calculating a noise floor for a multipath searching window and determining a first threshold and a second threshold. The step and means for categorizing further includes determining if the located energy peak exceeds the first threshold, labeling the located energy peak as a false alarm, if the located energy peak does not exceed the first threshold, determining if the located energy peak exceeds the second threshold and labeling the located energy peak as confident, if the located energy peak exceeds the second threshold. | 09-02-2010 |
Colin Zhang, Ambler, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080318991 | SPIROCYCLES AS INHIBITORS OF 11-BETA HYDROXYL STEROID DEHYDROGENASE TYPE 1 - The present invention relates to certain spirocyclic compounds that are inhibitors of 11-β hydroxyl steroid dehydrogenase type 1 (11βHSD1), compositions containing the same, and methods of using the same for the treatment of diabetes, obesity and other diseases. | 12-25-2008 |
| 20090291946 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS - The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess. | 11-26-2009 |
| 20100130467 | TRIAZOLOTRIAZINES AS KINASE INHIBITORS - The present invention is directed to [1,2,4]triazolo[4,3-b][1,2,4]triazines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. | 05-27-2010 |
| 20100137401 | 2-METHYLPROP ANAMIDES AND THEIR USE AS PHARMACEUTICALS - The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess. | 06-03-2010 |
| 20100173901 | Substituted Heterocyclic Compounds - The present invention relates to substituted heterocyclic compounds of Formula I: | 07-08-2010 |
| 20110136781 | IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS - The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. | 06-09-2011 |
| 20110144113 | TRIAZOLOTRIAZINES AS KINASE INHIBITORS - The present invention is directed to [1,2,4]triazolo[4,3-b][1,2,4]triazines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. | 06-16-2011 |
Colin Zhang, Lansdale, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080255154 | Amido Compounds And Their Use As Pharmaceuticals - The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess. | 10-16-2008 |
Donghui Zhang, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080219953 | Cosmid dna constructs and methods of making and using same - Methods of inducing immune responses in individuals against a pathogen are disclosed. Methods of treating individuals susceptible to or suffering from a disease associated with a genetic defect which results in the non-production or under production of a protein or the production of a non-functioning or partially functioning protein are disclosed. Methods of delivering a protein to an individual are disclosed. Pharmaceutical compositions that comprise cosmids are disclosed. | 09-11-2008 |
Fenglei Zhang, Lansdale, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090124649 | AZA SPIRO ALKANE DERIVATIVES AS INHIBITORS OF METALLOPROTEASES - The present invention provides a compound of Formula I or Formula II: | 05-14-2009 |
Gong Zhang, Murrysville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090081517 | Solid Oxide Fuel Cell Generator Including a Glass Sealant - A solid oxide fuel cell generator is provided for electrochemically reacting a fuel gas with a flowing oxidant gas at an elevated temperature to produce power. The generator includes a generator section receiving a fuel gas and a plurality of elongated fuel cells extending through the generator section and having opposing open fuel cell ends for directing an oxidant gas between opposing plena in the generator. A sealant defines a seal on the fuel cells adjacent at least one of the fuel cell ends. The sealant is a modified lanthanum borate aluminosilicate glass composition having a minimal amount of boron oxide and silica, and in which the sealant maintains substantially constant physical characteristics throughout multiple thermal cycles. | 03-26-2009 |
| 20090280362 | FUEL CELL GENERATOR WITH FUEL ELECTRODES THAT CONTROL ON-CELL FUEL REFORMATION - A fuel cell for a fuel cell generator including a housing including a gas flow path for receiving a fuel from a fuel source and directing the fuel across the fuel cell. The fuel cell includes an elongate member including opposing first and second ends and defining an interior cathode portion and an exterior anode portion. The interior cathode portion includes an electrode in contact with an oxidant flow path. The exterior anode portion includes an electrode in contact with the fuel in the gas flow path. The anode portion includes a catalyst material for effecting fuel reformation along the fuel cell between the opposing ends. A fuel reformation control layer is applied over the catalyst material for reducing a rate of fuel reformation on the fuel cell. The control layer effects a variable reformation rate along the length of the fuel cell. | 11-12-2009 |
| 20100325878 | Bi Containing Solid Oxide Fuel Cell System With Improved Performance and Reduced Manufacturing Costs - A method to provide a tubular, triangular or other type solid oxide electrolyte fuel cell has steps including providing a porous air electrode cathode support substrate, applying a solid electrolyte and cell to cell interconnection on the air electrode, applying a layer of bismuth compounds on the surface of the electrolyte and possibly also the interconnection, and sintering the whole above the melting point of the bismuth compounds for the bismuth compounds to permeate and for densification. | 12-30-2010 |
Guangyun Zhang, Furlong, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110111595 | Chemical mechanical polishing composition and methods relating thereto - A chemical mechanical polishing composition useful for chemical mechanical polishing of a substrate, wherein the substrate comprises a silicon oxide material and a silicon nitride material; and methods of making and using the chemical mechanical polishing composition. The chemical mechanical polishing composition comprises, as initial components: at least one of a first substance and a second substance; wherein the first substance is according to formula I | 05-12-2011 |
Han-Cheng Zhang, Landsdale, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090093634 | Substituted pyrroline kinase inhibitors - The present invention is directed to novel substituted pyrroline compounds useful as kinase or dual-kinase inhibitors and methods for treating or ameliorating a kinase or dual-kinase mediated disorder. | 04-09-2009 |
Hongqing Zhang, Bethlehem, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090258455 | METHOD OF MINIMIZING BEAM BENDING OF MEMS DEVICE BY REDUCING THE INTERFACIAL BONDING STRENGTH BETWEEN SACRIFICIAL LAYER AND MEMS STRUCTURE - The beam bending of a MEMS device is minimized by reducing interfacial strength between a sacrificial layer and a MEMS structure. | 10-15-2009 |
Hong Tao Zhang, Paoli, PA US
Hongxia Zhang, Allentown, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110136253 | Irinotecan Immunoassay - Novel conjugates of the pharmaceutically active metabolite of irinotecan and novel immunogens derived from this pharmaceutically active metabolite and monoclonal antibodies generated by these immunogens which are useful in immunoassays for the quantification and monitoring of the pharmaceutically active metabolite of irinotecan in biological fluids. | 06-09-2011 |
Huiping Zhang, Malvern, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100136105 | PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS FOR ADMINISTRATION OF HYDROPHOBIC DRUGS - The present invention relates to pharmaceutical compositions and methods for improved solubilization of triglycerides and improved delivery of therapeutic agents. Compositions of the present invention include a carrier, where the carrier is formed from a combination of a triglyceride and at least two surfactants, at least one of which is hydrophilic. Upon dilution with an aqueous medium, the carrier forms a clear, aqueous dispersion of the triglyceride and surfactants. | 06-03-2010 |
| 20100137271 | PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS FOR ADMINISTRATION OF HYDROPHOBIC DRUGS - Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs are provided. The pharmaceutical compositions include a therapeutically effective amount of a hydrophobic drug, preferably a steroid; a solubilizer, and a surfactant. The synergistic effect between the hydrophobic drug and the solubilizer results in a pharmaceutical formulation with improved dispersion of both the active agent and the solubilizer. As a result of the improved dispersion, the pharmaceutical composition has improved bioavailability upon administration. Methods of improving the bioavailability of hydrophobic drugs administered to a patient are also provided. | 06-03-2010 |
Jianying Zhang, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090246164 | TISSUE ADHESION - A method of adhering biological tissue that includes applying a bio-degradable adhesive to the tissue. The adhesive includes a moisture-curable, isocyanate-functional component prepared by reacting (a) a multi-functional isocyanate component and (b) a multi-functional active hydrogen component that includes at least 30% by weight, based upon the total weight of the multi-functional active hydrogen component, of a multi-functional active hydrogen reactant having an equivalent weight less than 100. The ratio R of active hydrogen groups to isocyanate groups can be less than 1.0. | 10-01-2009 |
| 20100036411 | ANTI-NO-REFLOW GUIDE WIRE FOR VASCULAR INTERVENTIONAL PROCEDURES - The present invention relates to compositions and methods for improving outcomes in vascular interventional procedures. In particular, the present invention relates to compositions and methods for improving outcomes in vascular interventional procedures using an anti-no-reflow guide wire that attenuates the “no-reflow” phenomenon that is associated with negative outcomes. | 02-11-2010 |
Jingfeng Zhang, Gibsonia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080302703 | CATALYTIC PROCESS FOR THE TREATMENT OF ORGANIC COMPOUNDS - A process for the catalytic reaction of organic compounds, in which the organic compounds are contacted with a catalyst comprising an interstitial metal hydride, having a reaction surface, to produce a catalyst-organic compound mixture, energy is applied, monatomic hydrogen is produced at the reaction surface of the interstitial metal hydride, and the organic compounds are reacted with the monatomic hydrogen. Reactions accomplished by this process include petroleum hydrocracking and hydrotreating processes. The method's performance can be further enhanced using radio frequency (RF) or microwave energy. | 12-11-2008 |
| 20100089741 | PRODUCTION OF BIOFUELS - A method is provided for the production of biofuels. The method includes contacting at least one of a plant oil, an animal oil and a mixture thereof with a catalyst including an acid or solid acid, thereby producing a catalyst-oil mixture. RF or microwave energy is applied to at least one of the catalyst, the plant oil, the animal oil, the mixture, and the catalyst-oil mixture to produce the biofuel. The process can be adjusted to produce gasoline, kerosene, jet fuel, or diesel range middle distillate products. | 04-15-2010 |
| 20100264015 | METHODS FOR PRODUCING BIODIESEL - Transesterification, esterification, and esterification-transesterification (both one-step and two-step) for producing biofuels. The process may be enhanced by one or more of the following: 1) applying microwave or RF energy; 2) passing reactants over a heterogeneous catalyst at sufficiently high velocity to achieve high shear conditions; 3) emulsifying reactants with a homogeneous catalyst; or 4) maintaining the reaction at a pressure at or above autogeneous pressure. Enhanced processes using one or more of these steps can result in higher process rates, higher conversion levels, or both. | 10-21-2010 |
| 20110119991 | INTERSTITIAL METAL HYDRIDE CATALYST ACTIVITY REGENERATION AND HYDROPROCESSING PROCESSES - The present invention relates to new processes for regenerating oxidized interstitial metal hydride containing catalysts prior to the use of such catalysts in a hydroprocessing process. Interstitial metal hydride containing catalysts are easily oxidized in the environment and once oxidized, the hydroprocessing activity of the interstitial metal hydrides is most often severely diminished and this lost activity due to oxidization of the iMeH is not susceptible to recovery under hydroprocessing conditions. As a result, these catalysts in the present art require considerable special handling in inert environments all through processes from fabrication, shipping, loading, use, and maintenance of the catalyst systems to protect the activity of the interstitial metal hydride components. The present invention embodies a process regenerating oxidized interstitial metal hydride containing catalysts prior to their use in a hydroprocessing environment, thereby eliminating the requirement for maintaining the interstitial metal hydride containing catalysts in an inert environment, and allowing the handling of such catalysts in an oxidized condition prior to use. | 05-26-2011 |
| 20110119992 | OXIDATION RESISTANT INTERSTITIAL METAL HYDRIDE CATALYSTS AND ASSOCIATED PROCESSES - The present invention relates to novel interstitial metal hydrides and catalyst containing interstitial metal hydrides that are resistant to oxidation and resultant loss of catalytic activity. The processes of the present invention include use of these improved, oxidation resistant interstitial metal hydride compositions for improved overall hydrogenation, product conversion, as well as sulfur reduction in hydrocarbon feedstreams. | 05-26-2011 |
| 20110119993 | HIGH SEVERITY HYDROPROCESSING INTERSTITIAL METAL HYDRIDE CATALYSTS AND ASSOCIATED PROCESSES - The present invention relates to the processing of hydrocarbon-containing feedstreams in the presence of an interstitial metal hydride containing catalyst and hydrogen at process conditions of at least 400 psig pressure and temperatures of at least 200° C. These processes use interstitial metal hydrides that possess significant hydrogen capacities and high hydrogen kinetics rate properties. The catalysts and processes of the present invention may be used with or without radio frequency or microwave energy and are preferably run under conditions of high hydrogen partial pressure above about 350 psia. The catalysts and processes of the present invention can improve overall hydrogenation, product conversion, as well as sulfur reduction in hydrocarbon feedstreams as compared to processes of the prior art operated under similar conditions. | 05-26-2011 |
Jingjun Zhang, Erie, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100175580 | ASSEMBLY AND METHOD FOR VEHICLE SUSPENSION - Truck assemblies, systems and methods are provided for transferring weight supported by various wheels, and axles. The vehicle suspension method includes operating the suspension in a first mode with a first effective suspension spring rate; and operating the suspension in a second mode with a second, different, effective suspension spring rate. | 07-15-2010 |
Jingtao Zhang, Lansdale, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090105375 | Ultrathin Multilayered Films for Controlled Release of Anionic Reagents - Multilayered films, particularly ultrathin multilayered films comprising cationic polymers which are useful for controlled release of anionic species, particularly for controlled release of nucleic acids. The multilayer films herein are useful for temporal controlled released of anionic species, particularly one or more anionic peptides, proteins, nucleic acids or other anionic biological agents. In one aspect, the invention relates to multilayer films which release anionic species (anions) with separate and/or distinct release profiles, particularly wherein the anions are one or more anionic peptides, proteins or nucleic acids or other anionic biological agents | 04-23-2009 |
| 20090170179 | COVALENT ASSEMBLY OF ULTRATHIN POLYMERIC FILMS - In one aspect, described herein are ultrathin films comprising an azlactone functionalized polymer and a primary amine functionalized polymer. Also described herein are ultrathin films including reactive, nonreactive, partially reactive/nonreactive, hydrophobic, hydrophilic, and mixed hydrophobic/hydrophilic ultrathin films. In another aspect, described herein are methods for making surface attached and freestanding ultrathin films. | 07-02-2009 |
| 20100048736 | ANIONIC CHARGE-DYNAMIC POLYMERS FOR RELEASE OF CATIONIC AGENTS - Materials and methods for the generation of polyelectrolyte multilayers that can erode to release cationic components. The multilayers comprise layers that contain one or more cations and one or more charge-dynamic anionic polymers. Charge-dynamic anionic polymers contain side chains having removable functional groups. Removal of the functional groups results in a change in the net change in the charge of the polymer which can disrupt interactions between cations and the anionic polymers and facilitate release of cations. | 02-25-2010 |
Jingyun Zhang, Upper Saint Clair, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110102565 | Spectral Imaging System - Macroscopic and microscopic samples are imaged through a spectral filter operable into the short wave infrared, e.g., to approximately 3200 nm. The sample is illuminated for reflective, transmissive, fluorescent and/or Raman imaging by a laser or metal-halide arc beam. The filter has tunable birefringent retarders distributed rotationally and stacked in stages leading up to a selection polarizer. Image forming optics and CCD cameras collect the luminance of each pixel in the spatially resolved image, at multiple wavelengths to which the filter is tuned successively. The filter stages have comb shaped transmission characteristics. Two filter stages with distinctly different characteristics can be cascaded, one or both being tunable. The combined transmission characteristic has narrow passbands where the bandpass peaks of the stages coincide and wide free spectral range where the peaks do not coincide. Embodiments are disclosed for forensic analysis, material composition and morphology, chemical compound identification and detection of biological species. | 05-05-2011 |
Jingyun Zhang, Upper St. Clair, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080212180 | POLARIZATION INDEPENDENT RAMAN IMAGING WITH LIQUID CRYSTAL TUNABLE FILTER - A high passband transmission ratio in microscopic Raman spectral imaging and other applications is obtained by splitting a light beam from an objective lens into two orthogonal polarized components processed along laterally spaced paths through the same liquid crystal tunable filter (LCTF) and imaging lens. At least one of the beams from a polarizing beam splitter is rotated using a wave plate, to cause both beams to be polarized at the nominal plane polarization angle required at the input to the LCTF. Laterally spaced beams emerge from the LCTF to be focused through a same imaging lens, as a single image on a CCD photosensor array. This arrangement ideally achieves 100% transmission in the passband, compared to 50% if the light beam had been coupled directly to the LCTF. | 09-04-2008 |
| 20090040519 | Method and apparatus for reconfigurable field of view in a fast-based imaging system - A system and method to obtain a variable field of view (FOV) of a sample without requiring an increase in an imaging CCD array size. In a fiber array spectral translator (FAST) based chemical imaging system, the fibers in the fiber bundle may be organized in different 2D “zones”. Each zone may include a predetermined number of fibers. Each 2D zone of fibers at the signal input end is organized as a separate linear array (1D) at the spectrometer slit input end. Depending on the user-selected FOV, one or more zones of fibers may be selected for signal input (into the spectrometer) by a motorized mobile slit port or linear translating stage, which will sequentially scan output from each selected linear fiber array into the spectrometer slit. The user can switch from one FOV size to another, thereby activating the linear translating stage to gather signals from appropriate linear fiber arrays corresponding to fiber zones associated with the selected FOV. A CCD imager may be used to collect optical data and generate 2D spatially accurate wavelength resolved images of the user-selected FOV. | 02-12-2009 |
| 20090091754 | Compact Spectrometer - Spectrometers, particularly compact spectrometers, are constructed without sacrificing performance characteristics, but with their instrument/device volume being reduced significantly. The light propagation path, either in transparent media or in free space, of the optical beams emitting from a small input aperture/slit of a spectrometer, is caused to be two-dimensional or unilateralized (propagating within a thin layer of air or media), enabling physical sizes of any optical elements needed thereafter to construct a spectrometer to be reduced significantly in one dimension. As a result, a significant reduction of instrument/device volume is achieved, which is applicable to and beneficial to either a classical dispersion spectrometer or a compact dispersion spectrometer. | 04-09-2009 |
| 20100265498 | METHOD AND APPARATUS FOR MICROLENS ARRAY/FIBER OPTIC IMAGING - A novel approach for chemical imaging is disclosed. In one embodiment, the disclosure relates to a system for producing a spatially accurate wavelength-resolved image of a sample from photons scattered from the sample, comprising an optical lens; a first optical fiber bundle of M fibers; a second optical fiber bundle of N fibers; an optical fiber switch; and a charge coupled device, wherein the image comprises plural sub-images, and wherein each sub-image is formed from photons scattered from a predetermined two spatial dimension portion of the sample, and wherein the scattered photons forming each sub-image have a predetermined wavelength different from a predetermined wavelength of scattered photons forming the other sub-images, and wherein the scattered photons for each sub-image are collected substantially simultaneously. | 10-21-2010 |
| 20100309454 | SPECTROMETERS MINIATURIZED FOR WORKING WITH CELLULAR PHONES AND OTHER PORTABLE ELECTRONIC DEVICES - Based on the present invention, superior compact spectrometers may be constructed and integrated into a cellular phone, or attached to a cellular phone. Such a cellular phone may be a PDA phone, which supplies electrical power to the said spectrometer, provided with data storage, signal processing capability, and real-time display. As a combined standalone system, it allows spectroscopic measurements to be fulfilled in real-time applications in field, and results can be sent out in wireless communication to a remote station or to another cellular phone user in order to share the measurement results right away. When the system is used with a laser to function as a Raman spectrometer system, it can fulfill many daily routine tasks encountered by ordinary civilians, for example, the blood glucose monitoring for diabetes patients at home in a non-invasive manner. | 12-09-2010 |
Jinhui Zhang, Wexford, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110057517 | Hybrid Conditioner for a Power System - A hybrid conditioner for filtering harmonics in a power system that includes a non-linear load. The hybrid conditioner includes an active filter structured and controlled to filter one or more high-order harmonic currents of the fundamental frequency, and a passive filter structured to filter one or more low-order harmonic currents of the fundamental frequency. The active filter and the passive filter are electrically connected in parallel with one another. The hybrid conditioner may also be for providing reactive power compensation for the power system, wherein the active filter is further controlled to provide a compensatory reactive power for compensating for the reactive power that is consumed by the load. The hybrid conditioner may also provide oscillation dampening for the power system, wherein the active filter is further controlled to damp oscillating currents that exist between the passive filter and the AC source. | 03-10-2011 |
Lihua(lily) Zhang, Collegeville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090270374 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES - Bicyclic nitrogen containing compounds and their use as antibacterials. | 10-29-2009 |
Lilu Zhang, Secane, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080275019 | METAL COMPLEX PROTEIN KINASE INHIBITORS - This inventive subject matter relates to novel metal complex protein kinases inhibitors, methods for making such compounds, and methods for using such compounds for treating diseases and disorders mediated by kinase activity. | 11-06-2008 |
Puwen Zhang, Audobon, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090156826 | METHODS FOR THE PREPARATION OF HYDROXY-SUBSTITUTED ARYL SULFAMIDE COMPOUNDS - The present invention is directed to processes for the preparation of hydroxy-substituted aryl sulfamide derivatives of the formula I or pharmaceutically acceptable salts, stereoisomers or tautomers thereof, which are monoamine reuptake inhibitors wherein the constituent variables are as defined herein. | 06-18-2009 |
Puwen Zhang, Audubon, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090093469 | Phenylaminopropanol Derivatives and Methods of Their Use - The present invention is directed to phenylaminopropanol derivatives of formula I: | 04-09-2009 |
| 20090099164 | Phenylaminopropanol Derivatives and Methods of Their Use - The present invention is directed to phenylaminopropanol derivatives of formula I: | 04-16-2009 |
| 20090111802 | CYCLOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS - This invention provides compounds of Formula (I): | 04-30-2009 |
| 20090281096 | CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS - Methods of using compounds which are progesterone receptor agonists for contraception and the treatment of progesterone-related maladies alone or in combination with an estrogen receptor agonist or progesterone receptor antagonist are provided. These compounds have the structure: | 11-12-2009 |
| 20090325916 | 5-ARYL INDAN-1-ONE AND ANALOGS USEFUL AS PROGESTERONE RECEPTOR MODULATORS - Compounds of formula I or II and pharmaceutical compositions and kits containing these compounds are provided. Also provided are methods of inducing contraception, providing hormone replacement therapy, treating cycle-related symptoms, or treating or preventing benign or malignant neoplastic disease using the compounds of formula I, formula II, or formula III. | 12-31-2009 |
| 20100029641 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE - The present invention is directed to aryl sulfamide derivatives of formula I: | 02-04-2010 |
Qiming Zhang, State College, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090024086 | Micro-steerable catheter - Micro-streerable catheters for use in delivering therapeutic treatment in the body, such as ablation and cauterization, and which exhibit precise movement are disclosed. Embodiments include electrical micro-catheters that comprise of electroactive polymers. A preferred embodiment includes a programmable catheter. | 01-22-2009 |
| 20090030152 | High Electric Energy Density Polymer Capacitors With Fast Discharge Speed and High Efficiency Based On Unique Poly (Vinylidene Fluoride) Copolymers and Terpolymers as Dielectric Materials - An improved charge or energy storage device having a dielectric charge or energy storage layer including: | 01-29-2009 |
| 20100067172 | HIGH ELECTRIC ENERGY DENSITY POLYMERIC COMPOSITIONS, METHODS OF THE MANUFACTURE THEREFOR, AND ARTICLES COMPRISING THE SAME - Examples of the present invention relate generally to high electric energy density polymer film capacitors with high charge-discharge efficiency and fast discharge speed. For example, a high energy density polymer capacitor may be fabricated using a polymer blend comprising one or more high dielectric constant PVDF-based polymers (including homopolymers, copolymers and/or terpolymers) and one or more other polymer with low dielectric loss and high volume resistivity compared to the one or more PVDF-based polymers. An example film capacitor may comprise a high temperature fluoropolymer with dielectric loss lower than 0.2% and good film manufacturability. Polymer films can be stretched and orientated at least in one direction to make thinner films with improved performance. Film capacitors can be made by winding metallized films, plain films with metal foils, or using a hybrid construction where the dielectric films comprise the new compositions. Capacitors can also have a multilayer construction where the films are metallized. | 03-18-2010 |
| 20110016885 | REFRIGERATION DEVICES BASED ON POLAR-POLYMERS - Cooling devices (i.e., a heat exchanger) based on polymers which exhibits a temperature change upon application or removal of an electrical field or voltage are disclosed. Also disclosed are methods for cooling using such polymers. | 01-27-2011 |
| 20110038625 | ELECTROMECHANICAL POLYMER ACTUATORS - An adaptive lens comprises an actuator and a lens, the lens being mechanically coupled to the actuator so that energization of the actuator adjusts a focal point of the lens. The actuator may comprise a multilayer stack of electromechanical polymer (EMP) layers, having electrodes configured to apply an electric field across each EMP layer. The actuator may be operable to move and/or deform a lens, so as to adjust the focus properties of the lens. In some examples, the actuator has an annular shape, supporting a lens within the inner radius of the annulus. The lens position may be adjusted in an axial direction. In other examples, the actuator may be mechanically coupled a surface of a deformable lens, either directly or through another element of a lens structure. A strain applied to the lens modifies a curved surface of the lens, hence modifying the focal length of the lens. | 02-17-2011 |
| 20110110015 | Methods to improve the efficiency and reduce the energy losses in high energy density capacitor films and articles comprising the same - A multilayer film useful for capacitive applications comprises a high energy density layer and a dielectric blocking layer. In some embodiments, a conducting film is located between the high energy density layer and the blocking layer. The high energy density layer may be a fluoropolymer, such as a polymer or copolymer of poly-1,1-difluoroethene or a derivative thereof. The multilayer film may have high energy density (for example,. >8 J/cm | 05-12-2011 |
Ruiyun Zhang, York, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090004462 | Inorganic-Organic Hybrid Nanocomposite Antiglare and Antireflection Coatings - Embodiments of this disclosure relate to compositions, and a method of making UV or heat curable anti-reflection and anti-glare hard coatings. Such coatings may be useful, for example, for simultaneously improving transmission and preventing undesired visible reflection on various monitor or display panels and optical lenses. For the panels with plastic covers, the coating will also improve the surface mechanical properties such as abrasion and scratch resistance. | 01-01-2009 |
| 20100028694 | Nanoengineered composite defog coating - An engineered nano-composite coating may include hydrophobic an hydrophilic domains, may be applied to transparent and non-transparent substrates using a continuous process, may be UV curable and may impart antifogging characteristics to the substrate. | 02-04-2010 |
Rulyun Zhang, York, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090232899 | Mucoadhesive nanocomposite delivery system - A nanocomposite delivery system uses chitosan as a mucoadhesive material encapsulated in a surface modified network of colloidal nanoporous nanoparticles, such as silica, or other colloid-forming materials, especially metal oxides. Drug delivery systems may be provided by binding a drug to the chitosan/silica nanocomposite, typically by adding a drug or other active agent during in-situ gellation of colloidal silica. When the active agent is, for example, amoxicillin or other antibiotic agent, the drug delivery system may be used in the treatment of stomach ulcers, for example. | 09-17-2009 |
Shaofeng Zhang, Exton, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110084203 | METHOD AND APPARATUS FOR PYROLYSIS-INDUCED CLEAVAGE IN PEPTIDES AND PROTEINS - A method and apparatus for conducting the rapid pyrolysis of peptides, proteins, polymers, and biological materials. The method can be carried out at atmospheric pressures and takes only about 5 to 30 seconds. The samples are cleaved at the C-terminus of aspartic acid. The apparatus employs a probe on which the sample is heated and digested components analyzed. | 04-14-2011 |
Shihai Zhang, State College, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090024086 | Micro-steerable catheter - Micro-streerable catheters for use in delivering therapeutic treatment in the body, such as ablation and cauterization, and which exhibit precise movement are disclosed. Embodiments include electrical micro-catheters that comprise of electroactive polymers. A preferred embodiment includes a programmable catheter. | 01-22-2009 |
| 20100067172 | HIGH ELECTRIC ENERGY DENSITY POLYMERIC COMPOSITIONS, METHODS OF THE MANUFACTURE THEREFOR, AND ARTICLES COMPRISING THE SAME - Examples of the present invention relate generally to high electric energy density polymer film capacitors with high charge-discharge efficiency and fast discharge speed. For example, a high energy density polymer capacitor may be fabricated using a polymer blend comprising one or more high dielectric constant PVDF-based polymers (including homopolymers, copolymers and/or terpolymers) and one or more other polymer with low dielectric loss and high volume resistivity compared to the one or more PVDF-based polymers. An example film capacitor may comprise a high temperature fluoropolymer with dielectric loss lower than 0.2% and good film manufacturability. Polymer films can be stretched and orientated at least in one direction to make thinner films with improved performance. Film capacitors can be made by winding metallized films, plain films with metal foils, or using a hybrid construction where the dielectric films comprise the new compositions. Capacitors can also have a multilayer construction where the films are metallized. | 03-18-2010 |
| 20110038625 | ELECTROMECHANICAL POLYMER ACTUATORS - An adaptive lens comprises an actuator and a lens, the lens being mechanically coupled to the actuator so that energization of the actuator adjusts a focal point of the lens. The actuator may comprise a multilayer stack of electromechanical polymer (EMP) layers, having electrodes configured to apply an electric field across each EMP layer. The actuator may be operable to move and/or deform a lens, so as to adjust the focus properties of the lens. In some examples, the actuator has an annular shape, supporting a lens within the inner radius of the annulus. The lens position may be adjusted in an axial direction. In other examples, the actuator may be mechanically coupled a surface of a deformable lens, either directly or through another element of a lens structure. A strain applied to the lens modifies a curved surface of the lens, hence modifying the focal length of the lens. | 02-17-2011 |
| 20110110015 | Methods to improve the efficiency and reduce the energy losses in high energy density capacitor films and articles comprising the same - A multilayer film useful for capacitive applications comprises a high energy density layer and a dielectric blocking layer. In some embodiments, a conducting film is located between the high energy density layer and the blocking layer. The high energy density layer may be a fluoropolymer, such as a polymer or copolymer of poly-1,1-difluoroethene or a derivative thereof. The multilayer film may have high energy density (for example,. >8 J/cm | 05-12-2011 |
Shujun Zhang, State College, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100133461 | NBT based lead-free piezoelectric materials for high power applications - Piezoelectric compounds of the formula xNa | 06-03-2010 |
| 20110017937 | RELAXOR-PT FERROELECTRIC SINGLE CRYSTALS - A <110> domain engineered relaxor-PT single crystals having a dielectric loss of about 0.2%, a high electromechanical coupling factor greater than about 85%, and high mechanical quality factor greater than about 500 is disclosed. In one embodiment, the relaxor-PT material has the general formula, Pb(B | 01-27-2011 |
Songwen Zhang, Lansdale, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080300235 | FXR Agonists for Reducing LOX-1 Expression - Provided are certain methods of treating at least one disease state characterized by elevated expression of the Lectin-like Oxidized Low-density Lipoprotein Receptor 1 (LOX-1) in a patient with farnesoid X receptor agonists. Also provided are certain methods of reducing expression of LOX-1 in a cell with farnesoid X receptor agonists. | 12-04-2008 |
| 20090163474 | FXR Agonists for the Treatment of Nonalcoholic Fatty Liver and Cholesterol Gallstone Diseases - Provided are certain methods of treating nonalcoholic fatty liver disease with farnesoid X receptor agonists. Also provided are certain methods of modulating levels of keratinocyte-derived chemokine (KC), alanine aminotransferase (ALT), aspartate aminotransferase (AST), cytokeratin 18 (CK-18), matrix metalloproteinase-9 (MMP-9), matrix metalloproteinase-14 (MMP-14), tissue inhibitor of metalloproteinase 1 (TIMP-1), and Cytochrome P450 2E1 (CYP2E1); certain methods of identifying FXR modulators; and certain methods of treating patients with existing cholesterol gallstone disease. | 06-25-2009 |
| 20090311271 | Methods and Compositions for Selective Inhibition of Ligand Binding to the Lectin-Like Receptor for Oxidized Low Density Lipoprotein (LOX-1) - The present invention provides methods of selectively inhibiting the binding of one ligand for LOX-1, but not one other ligand for LOX-1. Moreover, the invention relates to the identification of binding partners that act in a selective manner to inhibit the binding of one ligand to LOX-1, but not one other ligand for LOX-1, and methods of identifying such binding partners. Pharmaceutical compositions comprising the binding partners for LOX-1, in particular, anti-LOX-1 antibodies or fragments thereof, are also provided in the present invention. | 12-17-2009 |
Wei-Xian Zhang, Bethlehem, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090028810 | STABILIZATION OF BIOSOLIDS USING IRON NANOPARTICLES - This invention discloses a stabilized biosolids composition and a method for the stabilization of biosolids. It entails the use of a chemically and biologically reactive material, in the form of ultrafine iron particles. The nanometer-sized iron particles are capable of degrading odorous organosulfur compounds, transforming persistent and toxic organic pollutants such as PCBs and chlorinated pesticides, inhibiting the growth of pathogens by increasing pH and maintaining the increased pH of the stabilized biosolids, immobilizing toxic metal ions such as mercury and lead, and improving the overall quality of biosolids for land application and plant growth. | 01-29-2009 |
| 20110100928 | PREPARATION AND USE OF NANO SIZE PEROXIDE PARTICLES - Nano-size particles of calcium dioxide and magnesium dioxide for remediation of contaminated water or soil and processes for preparing and using nano-size particles of calcium dioxide and magnesium dioxide. | 05-05-2011 |
Xiaojun Zhang, Furlong, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090131473 | 2-(ARYLOXY) ACETAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS - The present invention relates generally to novel 2-(aryloxy)acetamides of Formula (I): | 05-21-2009 |
| 20100041664 | BICYCLIC LACTAM FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS - The present invention provides novel bicyclic lactams derivatives, and analogues thereof, of Formula (I): | 02-18-2010 |
| 20100113488 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS - The present invention relates generally to novel macrocycles of Formula (I): | 05-06-2010 |
| 20100227894 | BENZAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS - The present invention provides novel benzamide derivatives of Formula (I): | 09-09-2010 |
Xufang Zhang, Dresher, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080214511 | Tricyclic Anilide Spirolactam Cgrp Receptor Antagonists - The present invention is directed to compounds of Formula I: I (where A | 09-04-2008 |
| 20090221535 | IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA SUCH AS STREPTOCOCCUS AGALACTIAE - The present invention is directed to compounds of Formula I: I (where A | 09-03-2009 |
| 20100160334 | TRICYCLIC ANILIDE SPIROLACTAM CGRP RECEPTOR ANTAGONISTS - The present invention is directed to compounds of Formula I: I (where A | 06-24-2010 |
Xu-Fang Zhang, Dresher, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090131494 | Non-Nucleoside Reverse Transcriptase Inhibitors - Certain 1H-indole-2-carboxylates and -2-carboxamides are HIV reverse transcriptase inhibitors. These indole compounds and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. | 05-21-2009 |
| 20100113421 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS - Compounds of Formula (I) are HIV reverse transcriptase inhibitors, wherein X, R | 05-06-2010 |
Xumu Zhang, State College, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080293953 | Chiral spiro compounds and their use in asymmetric catalytic reactions - The present invention provides a chiral ligand, represented by a formula or its enantiomer: | 11-27-2008 |
| 20090198071 | TETRAPHOSPHORUS LIGANDS FOR CATALYTIC HYDROFORMYLATION AND RELATED REACTIONS - Tetraphosphorous ligands are combined with transition metal salts to form catalysts for use in hydroformylation, isomerization-hydroformylation, hydrocarboxylation, hydrocyan-ation, isomerization-formylation, hydroaminomethylation and similar related reactions. | 08-06-2009 |
Ye Zhang, Lower Gwynedd, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100048888 | Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules - The present invention relates to novel cationic lipids, transfection agents, microparticles, nanoparticles, and short interfering nucleic acid (siNA) molecules. The invention also features compositions, and methods of use for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity in a subject or organism. Specifically, the invention relates to novel cationic lipids, microparticles, nanoparticles and transfection agents that effectively transfect or deliver biologically active molecules, such as antibodies (e.g., monoclonal, chimeric, humanized etc.), cholesterol, hormones, antivirals, peptides, proteins, chemotherapeutics, small molecules, vitamins, co-factors, nucleosides, nucleotides, oligonucleotides, enzymatic nucleic acids, antisense nucleic acids, triplex forming oligonucleotides, 2,5-A chimeras, dsRNA, allozymes, aptamers, decoys and analogs thereof, and small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), short hairpin RNA (shRNA), and RNAi inhibitor molecules, to relevant cells and/or tissues, such as in a subject or organism. Such novel cationic lipids, microparticles, nanoparticles and transfection agents are useful, for example, in providing compositions to prevent, inhibit, or treat diseases, conditions, or traits in a cell, subject or organism. The compositions described herein are generally referred to as formulated molecular compositions (FMC) or lipid nanoparticles (LNP). | 02-25-2010 |
| 20100105933 | LIPID NANOPARTICLE BASED COMPOSITIONS AND METHODS FOR THE DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES - The present invention relates to novel cationic lipids, transfection agents, microparticles, nanoparticles, and short interfering nucleic acid (siNA) molecules. The invention also features compositions, and methods of use for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity in a subject or organism. Specifically, the invention relates to novel cationic lipids, microparticles, nanoparticles and transfection agents that effectively transfect or deliver biologically active molecules, such as antibodies (e.g., monoclonal, chimeric, humanized etc.), cholesterol, hormones, antivirals, peptides, proteins, chemotherapeutics, small molecules, vitamins, co-factors, nucleosides, nucleotides, oligonucleotides, enzymatic nucleic acids, antisense nucleic acids, triplex forming oligonucleotides, 2,5-A chimeras, dsRNA, allozymes, aptamers, decoys and analogs thereof, and small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), short hairpin RNA (shRNA), and RNAi inhibitor molecules, to relevant cells and/or tissues, such as in a subject or organism. Such novel cationic lipids, microparticles, nanoparticles and transfection agents are useful, for example, in providing compositions to prevent, inhibit, or treat diseases, conditions, or traits in a cell, subject or organism. The compositions described herein are generally referred to as formulated molecular compositions (FMC) or lipid nanoparticles (LNP). | 04-29-2010 |
| 20110092739 | Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules - The present invention relates to novel cationic lipids, transfection agents, microparticles, nanoparticles, and short interfering nucleic acid (siNA) molecules. The invention also features compositions, and methods of use for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity in a subject or organism. Specifically, the invention relates to novel cationic lipids, microparticles, nanoparticles and transfection agents that effectively transfect or deliver biologically active molecules, such as antibodies (e.g., monoclonal, chimeric, humanized etc.), cholesterol, hormones, antivirals, peptides, proteins, chemotherapeutics, small molecules, vitamins, co-factors, nucleosides, nucleotides, oligonucleotides, enzymatic nucleic acids, antisense nucleic acids, triplex forming oligonucleotides, 2,5-A chimeras, dsRNA, allozymes, aptamers, decoys and analogs thereof, and small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules, to relevant cells and/or tissues, such as in a subject or organism. Such novel cationic lipids, microparticles, nanoparticles and transfection agents are useful, for example, in providing compositions to prevent, inhibit, or treat diseases, conditions, or traits in a cell, subject or organism. The compositions described herein are generally referred to as formulated molecular compositions (FMC) or lipid nanoparticles (LNP). | 04-21-2011 |
Yingchao C. Zhang, Murrysville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100109187 | METHOD FOR PREPARING POLYURETHANE UREA-CONTAINING FILMS - Described is a method of preparing a cured, non-elastomeric polyurethane-containing film, the method including: | 05-06-2010 |
| 20100109188 | METHOD FOR PREPARING POLYURETHANE UREA-CONTAINING FILMS - A method of preparing a polyurethane-containing film including: | 05-06-2010 |
Yulian Zhang, Yardley, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090042893 | KINASE INHIBITORS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE - Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use. | 02-12-2009 |
| 20100160316 | QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS - The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 06-24-2010 |
| 20110021495 | QUINAZOLES USEFUL AS MODULATORS OF ION CHANNELS - The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 01-27-2011 |
Yuxun Zhang, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110118214 | LIGANDS SPECIFIC FOR CANNABINOID RECEPTOR SUBTYPE 2 - A compound of Formula I: (I) has activity as a cannabinoid receptor antagonist. In Formula 1, R1 is unsubstituted or substituted aryl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted heterocyclyl, unsubstituted or substituted aralkyl, or unsubstituted or substituted heteroaryl; R2 is unsubstituted or substituted alkyl, unsubstituted or substituted aryl, or unsubstituted or substituted heteroaryl; and R3 is unsubstituted or substituted alkyl, unsubstituted or substituted aralkyl, or unsubstituted or substituted heteroaralkyl; with the proviso that at least one of Ri and R3 is other than unsubstituted aralkyl or R2 is other than unsubstituted aryl. | 05-19-2011 |
Yuying Zhang, New Hope, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090203099 | ZYMOMONAS WITH IMPROVED ETHANOL PRODUCTION IN MEDIUM CONTAINING CONCENTRATED SUGARS AND ACETATE - Through screening of a | 08-13-2009 |
| 20090221078 | ZYMOMONAS WITH IMPROVED ETHANOL PRODUCTION IN MEDIUM CONTAINING CONCENTRATED SUGARS AND ACETATE - Through screening of a | 09-03-2009 |
| 20090246846 | ZYMOMONAS WITH IMPROVED XYLOSE UTILIZATION - Strains of | 10-01-2009 |
| 20090246876 | HIGH EXPRESSION ZYMOMONAS PROMOTERS - Identified are mutants of the promoter of the | 10-01-2009 |
Zhi-Qiang Zhang, Lansdale, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100215573 | IGF-1R SPECIFIC ANTIBODIES USEFUL IN THE DETECTION AND DIAGNOSIS OF CELLULAR PROLIFERATIVE DISORDERS - The present invention relates to mammalian antibodies, designated 12B1 and antigen-binding portions thereof that specifically bind to insulin-like growth factor I receptor (IGF-IR), preferably human IGF-IR. Also included are chimeric, bispecific, derivatized, single chain antibodies derived from the antibodies disclosed herein. Nucleic acid molecules encoding the mammalian antibodies as well as methods of use thereof are also disclosed. Also included are pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for treatment and diagnosis of pathological hyperproliferative oncogenic disorders associated with expression of IGf-1R. | 08-26-2010 |
Zhong Huai Zhang, Pottstown, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090049869 | Thermal Protection Sleeve With Knit Thermal Protection Features And Method Of Construction Thereof - A knit protective sleeve and method of construction thereof provides a continuous and seamless sleeve wall knit from one or more yarns extending between opposite open ends of the sleeve. At least one heat vent opening is integrally knit within the wall between the ends. | 02-26-2009 |
| 20100084825 | TEXTILE GASKET AND METHOD OF CONSTRUCTION THEREOF - A textile gasket and method of construction thereof for establishing a seal between mating members in a high temperature application is provided. The gasket has a knit, tubular body constructed at least in part of non-metallic, heat-resistant yarns. The body extends between opposite ends with at least one of the ends being rolled toward the other end to form a circumferentially extending rolled portion of a predetermined diameter for receipt between the mating members. | 04-08-2010 |
| 20110162126 | TRI-LAYER KNIT FABRIC, THERMAL PROTECTIVE MEMBERS FORMED THEREFROM AND METHODS OF CONSTRUCTION THEREOF - A knit fabric, protective sleeve and glove constructed therefrom has three knit layers knit constructed and knit to one another in a single knitting operation to provide the fabric as a single piece of knit material. The fabric includes an outer layer, an inner layer and an intermediate layer sandwiched between the outer and inner layers. The outer layer is knit with a first yarn, the inner layer is knit with a second yarn and the intermediate layer is knit with a third yarn in looped fashion about at least some of the first and second yarns to provide an integrally knit structure having three layers knit stitched together in a single knitting process. | 07-07-2011 |