Yuanlin Zhou, Richmond CA
Yuanlin Zhou, Richmond CA
Patent application number | Description | Published |
---|---|---|
20080287522 | BENZYLATED PDE4 INHIBITORS - The present invention is directed to a method for reducing the emetogenic effects of PDE inhibitors, and more particularly is directed to compounds having PDE4 inhibition activity with little or no emetogenic side-effects, and chemical methods including benzylation for preparing such compounds. A benzyl group may be attached to either a carbon or nitrogen atom of a PDE4 inhibitor. Suitable benzylation chemistry is to extract a hydrogen from a PDE4 inhibitor, preferably with a base, and then react the resulting nucleophilic PDE4 inhibitor with a benzylating agent, e.g., benzyl bromide or a derivative thereof. | 11-20-2008 |
20100152220 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS - Compounds of formula (Ia): | 06-17-2010 |
20100168167 | Piperidinones Useful in the Treatment of Inflammation - There is provided compounds of formula (I): wherein R | 07-01-2010 |
20100168170 | Piperidinones Useful in the Treatment of Inflammation - There is provided compounds of formula (I), wherein R | 07-01-2010 |
20110009439 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS - Compounds of formula (Ia): | 01-13-2011 |
20110172258 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS - Compounds of formula (Ia): | 07-14-2011 |
20120270901 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS - Compounds of formula (Ia): | 10-25-2012 |
20140371252 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS - Processes for making and using compounds of formula (I): | 12-18-2014 |