Yoshihiro Yamashita
Yoshihiro Yamashita, Hitachinaka JP
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20090099350 | Instrument and method for nucleic acid isolation - According to this invention, an instrument and a method for nucleic acid isolation is realized, whereby it is possible to prevent, for example, adherence of a discharged solution upon dispersion of such solution to the vicinity of a nucleic acid isolation column outlet. | 04-16-2009 |
20090111114 | RNA EXTRACTION METHOD, RNA EXTRACTION REAGENT, AND METHOD FOR ANALYZING BIOLOGICAL MATERIALS - A method to extract RNA with high purity from biological materials containing RNA in a safe, rapid, and simple procedure and a method to analyze it are provided. The procedure includes the steps of mixing a biological material containing RNA with a predetermined concentration of a chaotropic agent and a predetermined concentration of an organic solvent, allowing the mixed solution to contact a nucleic acid-binding solid phase, washing the nucleic-acid binding solid-phase to which RNA is bound, and eluting RNA from the nucleic-acid binding solid-phase having the bound RNA. Furthermore, the obtained RNA is analyzed by reverse transcriptase-polymerase chain reaction (RT-PCR) or the like. | 04-30-2009 |
20090186345 | Instrument and method for nucleic acid isolation - According to the present invention, purified nucleic acids are isolated without the complete removal of components of a washing reagent. Also, nucleic acids are isolated in an elution reagent by allowing a washing reagent comprising at least one component constituting a reaction solution that can be applied to a reaction involving nucleic acids to come into contact with a nucleic-acid-adsorbing solid phase so as to wash the solid phase, separating the washing reagent from the solid phase in a manner such that a certain amount of the washing reagent is allowed to remain in the solid phase, and allowing an elution reagent to come into contact with the nucleic-acid-adsorbing solid phase. | 07-23-2009 |
20090221060 | NUCLEIC ACID ANALYZER - It is an object of the present invention to prevent condensation occurring when reaction solutions in sealed vessels are heated in a nucleic acid analyzer for performing sequential processing in which individual reaction vessels are sequentially fed to a nucleic acid amplification unit in a given cycle. This invention relates to a nucleic acid analyzer including a vessel mounting rack capable of holding the plurality of reaction vessels, wherein the reaction vessel mounted on the vessel mounting rack is heated by an adjacent noncontact heat source and air circulation from the heat source to a reaction vessel upper portion, and a temperature of the reaction vessel upper portion is kept higher than a temperature of a reaction vessel lower portion. With this invention, condensation possibly occurring on the inner wall of the sealed vessel upper portion due to heating during nucleic acid amplification can be prevented, and more accurate nucleic acid analysis is enabled. | 09-03-2009 |
20110097240 | ANALYZER USING MAGNETIC PARTICLES - This invention provides an analyzer that uses magnetic particles, the analyzer being capable of removing inhibitors within a short time and reducing an analytical time. Magnetic particles | 04-28-2011 |
20130125671 | AUTOMATIC ANALYZER - Provided is an automatic analyzer that can efficiently supply a liquid, shorten an analysis cycle, and make analyses with high accuracy. The automatic analyzer includes a suction nozzle, a detection container, and a detector. The suction nozzle suctions a sample and a solution used for the detection of the sample. The suctioned sample and the solution are supplied to the detection container. The detector detects a signal from the sample. A vessel for the sample and a container for the solution are disposed below the detection container. | 05-23-2013 |
20130143234 | SAMPLE ANALYZING DEVICE AND SAMPLE ANALYZING METHOD - This invention provides a sample analyzing device and sample analyzing method designed to suppress nonuniform capture of magnetic particles ( | 06-06-2013 |
20140030167 | ANALYZER - This invention provides an analyzer that has a liquid dispense pipette dispensing liquids with higher accuracy and precision at higher speeds. The analyzer includes a drive mechanism having a stepping motor as a power source. The drive mechanism transmits power from a rotation output shaft of the stepping motor to a moving unit for executing a target motion via at least one power transmission unit. The amount of idling of the moving unit stemming from the stepping motor getting driven in reverse is calculated from the amount of movement of the moving unit, from the amount of pulses fed to the stepping motor, and from the amount of remaining pulses so as to perform motion control of the drive mechanism accordingly. | 01-30-2014 |
Yoshihiro Yamashita, Fukuchiyama-Shi JP
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20100265519 | DISPLACEMENT SENSOR - A displacement is accurately measured at high speed to a measurement object having various surface states. In a displacement sensor including a confocal optical system in which an objective lens is moved along an optical axis, light emitted from a laser diode is formed into a slit beam by a cylindrical lens, a Y-axis side orthogonal to the optical axis is narrowed such that the light is collected on a surface of a measurement object, and an X-axis orthogonal to the optical axis is elongated in order to average a component of the light reflected from the surface. A photodiode receives the light reflected from the surface of the measurement object through an opening disposed in a position of conjugation with the laser diode. The opening is formed into a slit shape that is short in the Y-axis while being long in the X-axis. The displacement of the surface is measured from a position of the objective lens when a light receiving signal becomes the maximum. | 10-21-2010 |
20110222286 | ILLUMINATING DEVICE AND METHOD FOR MANUFACTURING THEREOF - To provide a method for manufacturing a plurality of types of illuminating devices having different specifications while reducing cost. A substrate includes a common flexible portion and a plurality of units bendable with respect to the common portion, where the common portion includes a pad that is extended in the horizontal direction in the plane of the drawing and that is arranged for every predefined interval. In the present manufacturing method, a substrate piece is created by cutting the substrate mounted with the light emitting element in a first direction, the common portion in the substrate piece is formed according to the illuminating device to be manufactured, the relative position of the individual portion with respect to the formed common portion is respectively positioned, and the wiring for supplying power to the pad in the substrate piece is formed. | 09-15-2011 |
Yoshihiro Yamashita, Yamanashi JP
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20090289423 | SHAFT SEAL PACKING AND SHAFT SEAL STRUCTURE FOR VALVE - A shaft seal packing exhibits high sealability at the time of initial assembly and also exhibits, even after the packing is retightened, excellent sealability by an increased seal surface pressure obtained through an effect of pressing and by self-sealability obtained through an effect of fluid pressure. A shaft seal structure for a valve includes a body for a valve, a valve shaft, a valve disc disposed within the body so as to be rotatable or capable of ascending and descending, a valve shaft seal chamber having the valve shaft axially attached thereto, a shaft seal packing that is attached to the shaft seal chamber and comprises annular packing bodies stacked and substantially V-shaped in cross section, with stacked layer faces on the inner-diameter side of the packing bodies brought into tight contact with one another and stacked layer faces on the outer-diameter side of the packing bodies formed with prescribed gaps between the adjacent stacked layer faces. In the shaft seal structure for a valve, a tightening load on the packing bodies and fluid pressure are converted to a force in the diametrical direction owing to inclined angles of stacked layer faces on the inner-diameter side to attain a seal by a surface contact between the inner peripheral surface on the inner-diameter side and the outer peripheral surface of the valve shaft on a sliding side, and a lip part on the outer-diameter side is pushed and spread owing to the gaps to attain a seal by a line contact with the shaft seal chamber on a fixed side. | 11-26-2009 |
Yoshihiro Yamashita, Hitahinaka JP
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20090023904 | NUCLEIC ACID PURIFICATION INSTRUMENT - According to this invention, a nucleic acid purification instrument whereby it is possible to prevent dispersion of a mist that causes contamination upon discharge of a solution is realized. | 01-22-2009 |
Yoshihiro Yamashita, Anjo-City JP
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20120292153 | POWER TRANSMITTING DEVICE - A main shaft has a shaft cylindrical portion extending from an outer periphery of a large-diameter portion. A drum has a drum cylindrical portion extending from an outer periphery of a drum plate portion. An axial forward end of the drum cylindrical portion is arranged in an inside of the shaft cylindrical portion. A frictional engagement unit of a clutch is provided in an inside of the shaft cylindrical portion. A motor generator has a rotor, which is firmly fitted to outer walls of the large-diameter portion and the shaft cylindrical portion and rotatable relative to a stator. A working-oil supply passage is formed in an inside of an input shaft. | 11-22-2012 |
20130276576 | DRIVE FORCE TRANSMISSION APPARATUS - A first tubular shaft is placed on a radially outer side of a countershaft. A second tubular shaft is placed on a radially outer side of the first tubular shaft. A first driven gear is provided at one end portion of the first tubular shaft and is meshed with a first drive gear. A second driven gear is provided at one end portion of the second tubular shaft and is meshed with a second drive gear. A second secondary coupling portion is provided at the countershaft. A second primary coupling portion is provided at the other end portion of the first tubular shaft. The second primary coupling portion is engageable with the second secondary coupling portion. A third primary coupling portion is provided at the other end portion of the second tubular shaft. The third primary coupling portion is engageable with the second secondary coupling portion. | 10-24-2013 |
Yoshihiro Yamashita, Hitachinaka-Shi JP
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20130089464 | AUTOMATIC ANALYZER - According to an embodiment of the disclosure, the analyzer includes a reagent driving disk that accommodates a reagent configured for analysis and that transports the reagent to a desired position, and a fixed disk that has a reagent stand-by position in which to make a reagent container containing the reagent, temporarily stand by, and a magnetic particles stirring position for stirring magnetic particles. A portion of the reagent stand-by position is constituted by a loading system. A reagent container moving unit moves reagent containers containing the reagent, between the reagent driving unit and the fixed disk, according to analytical request status. Providing in a part of the fixed disk the loading system constructed so that reagent containers containing the reagent can be mounted therein during operation enables changing of reagent containers, irrespective of an operational status of the reagent driving disk, and the system to having cold-storage functionality. | 04-11-2013 |
Yoshihiro Yamashita, Yokohama-Shi JP
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20130197846 | THICKNESS MEASUREMENT APPARATUS AND METHOD THEREOF - A thickness measurement apparatus and method thereof being possible to measure an object to be inspected with required sensitivity stability and accuracy is provided. | 08-01-2013 |
Yoshihiro Yamashita, Hyogo JP
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20130334211 | INDUCTION HEATING APPARATUS CAPABLE OF AVOIDING UNSTABLE HEATING DUE TO LIMITATION OF HEATING OUTPUT - When the control unit makes both the first and second inverter circuits operational, the control unit controls the first and second inverter circuits by duty control such that an average heating output from the first inverter circuit reaches a predetermined first target heating output, and an average heating output from the second inverter circuit reaches a predetermined second target heating output. When the control unit makes one of the first and second inverter circuits operational in an automatic heating mode for automatic heating control according to a predetermined heating output sequence, the control unit inhibits the first and second inverter circuits from being controlled by the duty control. | 12-19-2013 |
Yoshihiro Yamashita, Tokyo JP
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20150037214 | AUTOMATIC ANALYZER - The automatic analyzer includes a suction nozzle; a liquid transfer syringe; a suction channel which connects the suction nozzle and the liquid transfer syringe; a flow cell which is arranged in the middle of the suction channel; a detector for sample analysis which is arranged in the flow cell; a reaction auxiliary liquid vessel and a cleaning liquid vessel which store liquids to be sucked in by the suction nozzle; means for supplying a diluting fluid to the vessels; a cleaning tank for dumping liquid remaining in the vessels; and a controller for supplying the diluting fluid to the vessels when the remaining liquid is discharged from the vessels and thereafter having the diluted remaining liquid sucked into the flow cell via the suction nozzle and having the sucked remaining liquid discharged to the cleaning tank. | 02-05-2015 |
20150056098 | SAMPLE ANALYSIS DEVICE AND SAMPLE ANALYSIS METHOD - A problem of a sample analysis device that uses magnetic particles is the difficulty in uniformly capturing magnetic particles, specifically the poor uniformity in the vicinity of channel side walls. This causes poor analysis accuracy and reproducibility. The present invention is intended to provide a means to uniformly capture magnetic particles in the vicinity of channel side walls. Specifically, the present invention provides an analysis device that includes a detection channel with an inlet and an outlet through which a sample liquid containing a specific substance and magnetic particles is flowed in and out of the channel, and magnetic field generating means capable of varying the magnitude of the magnetic field in a predetermined region of the detection channel. The width of the magnet in the detector is greater than the channel width. The detector can improve the analysis accuracy and reproducibility of the analysis device. | 02-26-2015 |