Yoshida, Tsukuba-Shi
Chuya Yoshida, Tsukuba-Shi JP
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20140221613 | NOVEL MODIFIED PROTEIN COMPRISING TANDEM-TYPE MULTIMER OF MUTANT EXTRACELLULAR DOMAIN OF PROTEIN G - The purpose of the present invention is: to provide an excellent protein which is further reduced in the binding property to an Fc region of an immunoglobulin and/or the binding property to an Fab region of the immunoglobulin in a weakly acidic region compared with that of a protein containing an extracellular domain of wild-type protein G, and which still keeps a high antibody-binding activity in a neutral region; and to capture and collect an antibody readily using the protein without denaturating the antibody. The present invention relates to: a protein that is reduced in the binding property to an Fc region of an immunoglobulin and/or the binding property to an Fab region of the immunoglobulin in a weakly acidic region compared with that of a multimer comprising an extracellular domain of wild type one, which is a domain having a binding activity to a protein comprising an Fc region of immunoglobulin G, while keeping a high antibody-binding activity in a neutral region, and also has a binding activity to a protein comprising the Fc region of immunoglobulin G, wherein the protein comprises a tandem-type multimer of a mutant of the extracellular domain; and others. | 08-07-2014 |
20150183820 | SCAVENGER CONTAINING PROTEIN FORMED FROM TANDEM-TYPE MULTIMER OF MUTANT EXTRACELLULAR DOMAIN OF PROTEIN G - The purpose of the present invention is to provide a superior protein with more decreased binding property to the Fc region of immunoglobulin and/or more decreased binding property to the Fab region thereof in the weakly acidic region in comparison with a protein containing an extracellular domain of a wild-type protein G without spoiling the high antibody binding property in the neutral region, and to allow the antibody to be easily captured and recovered without denaturing it by means of a capturing agent and column comprising the above protein. | 07-02-2015 |
Manabu Yoshida, Tsukuba-Shi JP
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20100025088 | CONDUCTIVE PATTERN FORMING FILM, AND CONDUCTIVE PATTERN FORMING METHOD AND CONDUCTIVE PATTERN FORMING APPARATUS FOR THE CONDUCTIVE PATTERN FORMING FILM - The present invention forms a conductive pattern using a simple process on a general plastic substrate having flexibility, and also provides a conductive pattern forming film that allows for easy formation of a conductive pattern using an apparatus that performs a simple process of oriented pressurization at low temperature, as well as a method for forming conductive pattern and a conductive pattern forming apparatus for the same. | 02-04-2010 |
20120222890 | CONDUCTIVE SUBSTRATE AND PROCESS FOR PRODUCING SAME - Provided are a conductive substrate which can be produced from inexpensive materials at a lower temperature than those for conventional substrates, and a process for producing the conductive substrate. The conductive substrate comprises a substrate ( | 09-06-2012 |
Tomoya Yoshida, Tsukuba-Shi JP
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20120229051 | FIELD EMISSION DEVICE - In a field emission device, the fundamental cause of spherical aberration in an emitted electron beam trajectory is eliminated or mitigated. An aberration suppressor electrode | 09-13-2012 |
Yoshiki Yoshida, Tsukuba-Shi JP
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20150013470 | METHOD AND APPARATUS FOR MEASURING A PULSATINGLY FLUCTUATING FLOW RATE | 01-15-2015 |
20150112614 | FLOW RATE MEASUREMENT METHOD AND APPARATUS - Method and apparatus capable of accurately measuring a flow rate using Gaussian quadrature even under a small number of measurement points are provided. An average for the y-coordinate of values of normal-directional component with respect to the cross-section represented by v | 04-23-2015 |
Yu Yoshida, Tsukuba-Shi JP
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20150025237 | Methods and Compounds Useful in the Synthesis of Orexin-2 Receptor Antagonists - The present disclosure provides compounds and methods that are useful for the preparation of compounds useful as orexin-2 receptor antagonists. | 01-22-2015 |