Patent application number | Description | Published |
20090238823 | Antigen binding proteins capable of binding thymic stromal lymphopoietin - The present disclosure provides compositions and methods relating to antigen binding proteins which bind to human thymic stromal lymphopoietin (TSLP), including antibodies. In particular embodiments, the disclosure provides fully human, humanized and chimeric anti-TSLP antibodies and derivatives of such antibodies. The disclosure further provides nucleic acids encoding such antibodies and antibody fragments and derivatives, and methods of making and using such antibodies including methods of treating and preventing TSLP-related inflammatory and fibrotic disorders. | 09-24-2009 |
20110274687 | METHODS OF TREATING TSLP-RELATED INFLAMMATORY DISORDERS - The present disclosure provides compositions and methods relating to antigen binding proteins which bind to human thymic stromal lymphopoietin (TSLP), including antibodies. In particular embodiments, the disclosure provides fully human, humanized and chimeric anti-TSLP antibodies and derivatives of such antibodies. The disclosure further provides nucleic acids encoding such antibodies and antibody fragments and derivatives, and methods of making and using such antibodies including methods of treating and preventing TSLP-related inflammatory and fibrotic disorders. | 11-10-2011 |
20120190829 | ANTIGEN BINDING PROTEINS CAPABLE OF BINDING THYMIC STROMAL LYMPHOPOIETIN - The present disclosure provides compositions and methods relating to antigen binding proteins which bind to human thymic stromal lymphopoietin (TSLP), including antibodies. In particular embodiments, the disclosure provides fully human, humanized and chimeric anti-TSLP antibodies and derivatives of such antibodies. The disclosure further provides nucleic acids encoding such antibodies and antibody fragments and derivatives, and methods of making and using such antibodies including methods of treating and preventing TSLP-related inflammatory and fibrotic disorders. | 07-26-2012 |
Patent application number | Description | Published |
20100277607 | IMAGE SENSOR WITH HIGH DYNAMIC RANGE IMAGING AND INTEGRATED MOTION DETECTION - This disclosure describes: (1) two different schemes to enhance dynamic range, (2) a new motion detection scheme using in-pixel digital storage, and (3) the motion detection in high illumination for CMOS image sensors. The schemes may be implemented in a small pixel size and easily incorporated in simple column-level circuits for existing CMOS image sensor systems. | 11-04-2010 |
20110193633 | BIOAMPLIFIER FOR NEURAL INTERFACES - A bioamplifier that includes a high pass filter, open-loop amplifier, and low pass filter in an area efficient design that can be used in implantable neural interfaces. The high pass filter can be implemented by using a switch-capacitance resistor coupled with parasitic capacitance of the electrode. The amplifier can be chopper stabilized and can include a high gain, current-ratio first stage followed by one or more dimension-ratio stages. The low pass filter utilizes the output impedance of the open-loop amplifier to form an embedded g | 08-11-2011 |
20120302856 | DISTRIBUTED, MINIMALLY-INVASIVE NEURAL INTERFACE FOR WIRELESS EPIDURAL RECORDING - A neural interface for measuring or stimulating brain neural activity, either as a standalone unit or as a part of a larger system of similar neural interfaces. The neural interface includes a bolt-shaped housing having a tool-engaging head and threaded shank with internal circuitry and at least one electrode. In use, the housing is threaded into a cranial bore such that the electrode contacts the outer surface of the meninges. The neural interface circuitry includes an SAR ADC that provides at least rail-to-rail operation to convert received signals from the electrode(s) into digital data that can be modulated and wirelessly transmitted by intra-skin or other suitable communication. | 11-29-2012 |
20130079615 | NEURAL PROBE WITH OPTICAL STIMULATION CAPABILITY - A neural probe is disclosed for optically stimulating or silencing neurons and recording electrical responses to the stimulus. Using patterning techniques, an integral optical waveguide may be fabricated on the probe for transmitting neuron-affecting light from a light source to a probe tip. The probe tip may include one or more electrodes to receive electrical responses from stimulated neurons for recording or further processing. According to various embodiments, the disclosed neural probes may utilize multiple light sources simultaneously, switch between multiple light sources, or utilize a single light source to stimulate or silence multiple neuron locations simultaneously via multiple probe tips or via multiple light-emitting sites located along the length of the probe. Neural probes are thereby provided that have sufficient spatial resolution to accurately target, stimulate, and record the reaction of neurons, or as few as a single neuron, utilizing a slim, compact structure. | 03-28-2013 |
20130130301 | MICROFLUIDIC PLATFORM FOR DISCRETE CELL ASSAY - A microfluidic chamber for use in individual cell assays. The microfluidic chamber includes a cell microchamber having an interior region and front and rear valves, each of which are separately controllable so that they can be selectively opened and closed to thereby permit the transference of an individual cell into and out of the interior region. Cell secretion and contact interaction studies can be carried out using the microchambers, with the valves permitting either complete isolation or perfusion media flow through the microchambers. An internal perfusion wall can be included to partition the microchamber for non-contact perfusion studies of secretion interactions between cells. | 05-23-2013 |
20140093953 | NON-ADHERENT CELL SUPPORT AND MANUFACTURING METHOD - A non-adherent cell support for use as a substrate in fluidic chambers used for cell culturing and assays. The non-adherent cell support allows for the formation of sphere cultures from single cells, which can better mimic primary tumor-like behavior in the study of cancer stem cells. The non-adherent cell support can allow for adhesive culturing and may include a hydrophobic substrate having a lower body and a raised support structure extending upwardly from an upper surface of the body. The support structure comprises one or more vertically extending support members that extend from a proximal portion at the upper surface of the body to a distal end spaced from the upper surface of the body. The support structure may be formed from a biocompatible material such as poly-2-hydroxyethyl methacrylate, polydimethylsiloxane, polymethyl methacrylate, polystyrene, or a polyethylene glycol diacrylate-based hydrogel. | 04-03-2014 |
20140093962 | NON-ADHERENT CELL SUPPORT AND MANUFACTURING METHOD - A non-adherent cell support for use as a substrate in fluidic chambers used for cell culturing and assays. The non-adherent cell support allows for the formation of sphere cultures from single cells, which can better mimic primary tumor-like behavior in the study of cancer stem cells. The non-adherent cell support can allow for adhesive culturing and may include a hydrophobic substrate having a lower body and a raised support structure extending upwardly from an upper surface of the body. The support structure comprises one or more vertically extending support members that extend from a proximal portion at the upper surface of the body to a distal end spaced from the upper surface of the body. The support structure may be formed from a biocompatible material such as poly-2-hydroxyethyl methacrylate, polydimethylsiloxane, polymethyl methacrylate, polystyrene, or a polyethylene glycol diacrylate-based hydrogel. | 04-03-2014 |
20140118592 | CMOS IMAGE SENSORS WITH FEATURE EXTRACTION - A CMOS imaging sensor with ernbedded feature extraction capability operatable in different modes by a method that includes the steps of: (a) operating the CMOS imaging sensor in a motion-detecting mode at a first power level using circuitry on the imaging sensor that generates motion data based on received images detected by pixels in the pixel array; (b) switching the imaging sensor from the motion-detecting mode to a feature extraction mode in response to detecting motion; and (c) operating the imaging sensor in the feature extraction mode at a second power level that is higher than the first power level. | 05-01-2014 |
Patent application number | Description | Published |
20100239549 | ALPHA LIPOIC ACID CAPSULE COMPOSITION STABILIZED IN WATER PHASE AND METHOD FOR PREPARING THE SAME - The present invention relates to an alpha lipoic acid capsule composition stabilized in aqueous phase, which can effectively prevent alpha lipoic acid from decomposing due to external environmental conditions, such as water, temperature, light, and the like, and can maintain the stability of alpha lipoic acid from the interaction between the lipoic acid and other materials, which are added together with the lipoic acid when the lipoic acid is applied to cosmetics, foods, or medical supplies, by mixing water-dispersed alpha lipoic acid, a water-insoluble polymer having self-emulsification properties, and a hydrophilic solvent, thus capsulating alpha lipoic acid, and to a method of preparing the same. | 09-23-2010 |
20110300479 | TONER COMPOSITION WITH BROAD FUSING TEMPERATURE RANGE AND PROCESS FOR PREPARING THE SAME - The present invention relates to a toner composition with a broad fusing temperature range and a process for preparing the same. The toner composition according to the present invention creates entanglement between adjacent polymer chains using a non-linear polyester resin having a branch structure, provides elasticity to molten materials by the branch structure when the resin is molten, prevents the molten materials from being transferred to the surface of a roller at a high temperature, and thereby increases the maximum fusing temperature. Therefore, as the average branch number per polyester resin increases, the maximum fusing temperature rises and the fusing temperature range of the toner composition can be widened. | 12-08-2011 |
Patent application number | Description | Published |
20090216747 | System and method for detecting, collecting, analyzing, and communicating event-related information - A system and method involves detecting operational social disruptive events on a global scale, assigning disease event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling disease propagation for containment and forecasting purposes. | 08-27-2009 |
20090216860 | SYSTEM AND METHOD FOR DETECTING, COLLECTING, ANALYZING, AND COMMUNICATING EVENT RELATED INFORMATION - A system and method involves detecting operational social disruptive events on a global scale, assigning disease event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling disease propagation for containment and forecasting purposes. | 08-27-2009 |
20120197896 | SYSTEM AND METHOD FOR DETECTING, COLLECTING, ANALYZING, AND COMMUNICATING EVENT-RELATED INFORMATION - A system and method involves detecting operational social disruptive events on a global scale, assigning event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling propagation of events for containment and forecasting purposes. | 08-02-2012 |
20150067570 | Method and Apparatus for Enhancing User Interface in a Device with Touch Screen - The present invention provides method and apparatus for providing an enhanced user interface at devices equipped with touch screens. The present invention enables users to more easily and accurately select an object among multiple selectable objects competing within limited screen space by enlarging the desired object as user's finger or a stylus pen approaches the object before physically touching it on the touch screen. | 03-05-2015 |
Patent application number | Description | Published |
20100136521 | Devices And Methods For Detection Of Microorganisms - The present invention features methods and devices for microorganisms through detecting Mie light scattering from immunoagglutinated beads. The methods feature providing a first bead suspension with antibody specific for the microorganism conjugated to beads; mixing the first bead suspension with a sample to form a first mixture; irradiating the first mixture with first incident light; detecting forward light scattering at a first angle with respect to the first incident light, where the first angle being between about 30 to 60 degrees; determining l from the light scattering; providing a second bead suspension with no antibody and simultaneously measuring l | 06-03-2010 |
20100136610 | Methods And Microfluidic Devices For Single Cell Detection Of Escherichia Coli - The present invention features a microfluidic device for detecting | 06-03-2010 |
20130149710 | MICRODROPLET-MANIPULATION SYSTEMS AND METHODS FOR AUTOMATED EXECUTION OF MOLECULAR BIOLOGICAL PROTOCOLS - Disclosed herein are automated systems for performing various biochemical and molecular biological procedures, including processor-controlled execution of protocols involving multiple steps performed in, on, or with liquid microdroplets. Example protocols are the various Polymerase Chain Reaction (PCR) protocols, but the subject systems are not limited to performing PCR protocols. Formation of a microdroplet of the sample for use in the described systems is achieved by bringing an amount of the sample into contact with a hydrophobic milieu, such as a superhydrophobic surface or hydrophobic liquid. | 06-13-2013 |
20130244339 | DEVICE AND METHOD FOR PERFORMING A DIAGNOSTIC TEST - A device and method for performing a point of care diagnostic test for detecting and quantifying at least one analyte in a biological sample (e.g., a body fluid). A device may include an immunoassay apparatus and a holder with an adjustable variable angle stage for positioning the immunoassay apparatus relative to a light source and a detector device so as to optimize the angle of incidence and angle of radiation to optimize an elastic light scattering signal from the immunoassay apparatus. The elastic light scattering signal may be used to quantify the amount of the analyte(s) of interest present in the sample. The device is based upon elastic light scattering, so the variation in the angle of incidence and angle of reflection are optimized to maximize signal generation due to elastic light scattering. | 09-19-2013 |
20140213468 | DEVICE AND METHOD FOR PERFORMING A DIAGNOSTIC TEST - Devices and methods for performing a point of care diagnostic test for detecting and quantifying at least one analyte in a biological sample. The device may include an immunoassay apparatus and a holder with a variable angle stage for positioning the immunoassay apparatus relative to a light source and a detector device. In one embodiment, the device is based upon elastic light scattering, so the variation in the angle of incidence and angle of reflection are optimized to maximize signal generation due to elastic light scattering. The detector device may include a wired or wireless connection to a computer network for communicating with an electronic medical records system, uploading the amount or concentration of at least one analyte present in the sample to the electronic medical records system, or querying a decision support algorithm stored in a computer readable format. The detector device may further include an onboard interpretive algorithm. | 07-31-2014 |
Patent application number | Description | Published |
20100283069 | Optical systems fabricated by printing-based assembly - The present invention provides optical devices and systems fabricated, at least in part, via printing-based assembly and integration of device components. In specific embodiments the present invention provides light emitting systems, light collecting systems, light sensing systems and photovoltaic systems comprising printable semiconductor elements, including large area, high performance macroelectronic devices. Optical systems of the present invention comprise semiconductor elements assembled, organized and/or integrated with other device components via printing techniques that exhibit performance characteristics and functionality comparable to single crystalline semiconductor based devices fabricated using conventional high temperature processing methods. Optical systems of the present invention have device geometries and configurations, such as form factors, component densities, and component positions, accessed by printing that provide a range of useful device functionalities. Optical systems of the present invention include devices and device arrays exhibiting a range of useful physical and mechanical properties including flexibility, shapeability, conformability and stretchability. Optical systems of the present invention include, however, devices and device arrays provided on conventional rigid or semi-rigid substrates, in addition to devices and device arrays provided on flexible, shapeable and/or stretchable substrates. | 11-11-2010 |
20110171813 | Release Strategies for Making Transferable Semiconductor Structures, Devices and Device Components - Provided are methods for making a device or device component by providing a multilayer structure having a plurality of functional layers and a plurality of release layers and releasing the functional layers from the multilayer structure by separating one or more of the release layers to generate a plurality of transferable structures. The transferable structures are printed onto a device substrate or device component supported by a device substrate. The methods and systems provide means for making high-quality and low-cost photovoltaic devices, transferable semiconductor structures, (opto-)electronic devices and device components. | 07-14-2011 |
20110266561 | Optical Systems Fabricated by Printing-Based Assembly - The present invention provides optical devices and systems fabricated, at least in part, via printing-based assembly and integration of device components. In specific embodiments the present invention provides light emitting systems, light collecting systems, light sensing systems and photovoltaic systems comprising printable semiconductor elements, including large area, high performance macroelectronic devices. Optical systems of the present invention comprise semiconductor elements assembled, organized and/or integrated with other device components via printing techniques that exhibit performance characteristics and functionality comparable to single crystalline semiconductor based devices fabricated using conventional high temperature processing methods. Optical systems of the present invention have device geometries and configurations, such as form factors, component densities, and component positions, accessed by printing that provide a range of useful device functionalities. Optical systems of the present invention include devices and device arrays exhibiting a range of useful physical and mechanical properties including flexibility, shapeability, conformability and stretchablity. Optical systems of the present invention include, however, devices and device arrays provided on conventional rigid or semi-rigid substrates, in addition to devices and device arrays provided on flexible, shapeable and/or stretchable substrates. | 11-03-2011 |
20110316120 | Release Strategies for Making Transferable Semiconductor Structures, Devices and Device Components - Provided are methods for making a device or device component by providing a multilayer structure having a plurality of functional layers and a plurality of release layers and releasing the functional layers from the multilayer structure by separating one or more of the release layers to generate a plurality of transferable structures. The transferable structures are printed onto a device substrate or device component supported by a device substrate. The methods and systems provide means for making high-quality and low-cost photovoltaic devices, transferable semiconductor structures, (opto-)electronic devices and device components. | 12-29-2011 |
20140216524 | ARRAYS OF ULTRATHIN SILICON SOLAR MICROCELLS - Provided are solar cells, photovoltaics and related methods for making solar cells, wherein the solar cell is made of ultrathin solar grade or low quality silicon. In an aspect, the invention is a method of making a solar cell by providing a solar cell substrate having a receiving surface and assembling a printable semiconductor element on the receiving surface of the substrate via contact printing. The semiconductor element has a thickness that is less than or equal to 100 μm and, for example, is made from low grade Si. | 08-07-2014 |
20140361409 | Release Strategies for Making Transferable Semiconductor Structures, Devices and Device Components - Provided are methods for making a device or device component by providing a multi layer structure having a plurality of functional layers and a plurality of release layers and releasing the functional layers from the multilayer structure by separating one or more of the release layers to generate a plurality of transferable structures. The transferable structures are printed onto a device substrate or device component supported by a device substrate. The methods and systems provide means for making high-quality and low-cost photovoltaic devices, transferable semiconductor structures, (opto-)electronic devices and device components. | 12-11-2014 |
20140373898 | OPTICAL SYSTEMS FABRICATED BY PRINTING-BASED ASSEMBLY - Provided are optical devices and systems fabricated, at least in part, via printing-based assembly and integration of device components. In specific embodiments the present invention provides light emitting systems, light collecting systems, light sensing systems and photovoltaic systems comprising printable semiconductor elements, including large area, high performance macroelectronic devices. Optical systems of the present invention comprise semiconductor elements assembled, organized and/or integrated with other device components via printing techniques that exhibit performance characteristics and functionality comparable to single crystalline semiconductor based devices fabricated using conventional high temperature processing methods. Optical systems of the present invention have device geometries and configurations, such as form factors, component densities, and component positions, accessed by printing that provide a range of useful device functionalities. Optical systems of the present invention include devices and device arrays exhibiting a range of useful physical and mechanical properties including flexibility, shapeability, conformability and stretchablity. | 12-25-2014 |
Patent application number | Description | Published |
20100069579 | Activated Polyoxazolines and Compositions Comprising the Same - The present disclosure provides terminally activated monofunctional POZ derivatives having a range of functional active groups allowing conjugation of the monofunctional POZ derivatives to a variety of target molecules under a wide range of reaction conditions to produce a hydrolytically stable target molecule-POZ conjugate. Furthermore, the present disclosure provides novel methods of synthesis for the disclosed terminally activated monofunctional POZ derivatives and hydrolytically stable target molecule-POZ conjugates created using the disclosed terminally activated monofunctional POZ derivatives. | 03-18-2010 |
20100330023 | Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same - The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents. | 12-30-2010 |
20110009594 | MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME - The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents. | 01-13-2011 |
20110123453 | Polyoxazolines with Inert Terminating Groups, Polyoxazolines Prepared from Protected Initiating Groups and Related Compounds - The present disclosure provides novel functional polyoxazoline derivatives prepared by terminating polyoxazoline polymerization with inert chemical groups. In addition, the present disclosure demonstrates the synthesis of novel electrophilic initiators with protected functional groups capable of initiating oxazoline polymerization and capable of surviving the conditions of polymerization. These initiators are used to synthesize the above inert-terminal polyoxazoline derivatives as well as other poly-oxazolines with active terminal groups. Furthermore, the present disclosure provides for polyoxazoline-lipid conjugates and liposomal compositions prepared using such polyoxazoline-lipid conjugates. Methods of using the foregoing to prepare conjugates with target molecules are also disclosed. | 05-26-2011 |
20120123055 | Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same - The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents. | 05-17-2012 |
20120136123 | Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same - The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents. | 05-31-2012 |
20130177521 | Subcutaneous Delivery of Poly(oxazoline) Conjugates - The present disclosure provides polymer conjugates comprising a polymer and an agent, the agent linked to the polymer via a linking group containing a hydrolyzable moiety. | 07-11-2013 |
20140011964 | Activated Polyoxazolines and Conjugates and Compositions Comprising the Same - The present disclosure provides POZ derivatives having a range of active functional groups allowing conjugation of POZ derivatives to a variety of target molecules under a wide range of reaction conditions to produce a hydrolytically stable target molecule-POZ conjugate. Furthermore, the present disclosure provides novel methods of synthesis for the disclosed POZ derivatives and hydrolytically stable target molecule-POZ conjugates created using the disclosed terminally activated monofunctional POZ derivatives. In one embodiment, the POZ derivative is a terminally activated monofunctional POZ derivative. | 01-09-2014 |
20140066577 | Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same - The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents. | 03-06-2014 |
20140112880 | SUBCUTANEOUS DELIVERY OF POLY(OXAZOLINE) POLYMER CONJUGATES - The present disclosure provides polymer conjugates comprising a polymer and an agent, the agent linked to the polymer via a linking group containing a hydrolyzable moiety. | 04-24-2014 |
20140271527 | SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS - The present disclosure provides polymer conjugates comprising a polymer and an agent, the agent linked to the polymer via a linking group containing a cleavable moiety. | 09-18-2014 |
20150079658 | Activated Polyoxazolines and Conjugates and Compositions Comprising the Same - The present disclosure provides POZ derivatives having a range of active functional groups allowing conjugation of POZ derivatives to a variety of target molecules under a wide range of reaction conditions to produce a hydrolytically stable target molecule-POZ conjugate. Furthermore, the present disclosure provides novel methods of synthesis for the disclosed POZ derivatives and hydrolytically stable target molecule-POZ conjugates created using the disclosed terminally activated monofunctional POZ derivatives. In one embodiment, the POZ derivative is a terminally activated monofunctional POZ derivative. | 03-19-2015 |
20150080538 | Polyoxazolines with Inert Terminating Groups, Polyoxazolines Prepared from Protected Initiating Groups and Related Compounds - The present disclosure provides novel functional polyoxazoline derivatives prepared by terminating polyoxazoline polymerization with inert chemical groups. In addition, the present disclosure demonstrates the synthesis of novel electrophilic initiators with protected functional groups capable of initiating oxazoline polymerization and capable of surviving the conditions of polymerization. These initiators are used to synthesize the above inert-terminal polyoxazoline derivatives as well as other polyoxazolines with active terminal groups. Furthermore, the present disclosure provides for polyoxazoline-lipid conjugates and liposomal compositions prepared using such polyoxazoline-lipid conjugates. Methods of using the foregoing to prepare conjugates with target molecules are also disclosed. | 03-19-2015 |
Patent application number | Description | Published |
20110269210 | ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES - Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and that exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions generally comprise at least one of an additional enzyme, a detergent,.a surfactant, a chelator, an oxidizing agent, an acidulant, an alkalizing agent, a source of peroxide, a source of hardness, a salt, a detergent complexing agent, a polymer, a stabilizing agent, or a fabric conditioner. Also disclosed are detergent formulations comprising the variants. Methods of using the compositions for desizing woven material and washing or cleaning items, such as dishes or laundry, are disclosed. Kits related thereto are also provided. | 11-03-2011 |
20110300201 | DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE - The invention provides methods, compositions, systems, and kits that include an enzyme/substrate co-delivery system. The liquid delivery system includes at least one enzyme encapsulated in a water-soluble polymeric matrix and a substrate for the enzyme in a carrier liquid in which the polymeric matrix is insoluble. When water is added, the polymeric matrix is solubilized and enzyme is released from the matrix, permitting catalytic action upon the substrate. | 12-08-2011 |
20120036649 | ENZYMATIC TEXTILE BLEACHING COMPOSITIONS AND METHODS OF USE THEREOF - Described are compositions and methods for enzymatic bleaching of textiles. A perhydrolase enzyme is used in combination with an ester substrate and hydrogen peroxide to produce a peracid for textile bleaching. Textiles bleached by the methods herein exhibit increased dye uptake, decreased textile damage, and/or bulkier softer handle than textiles bleached by conventional chemical bleaching processes. | 02-16-2012 |
20130111674 | TREATMENT OF KERATINOUS FIBERS WITH AN ENZYME HAVING PERHYDROLASE ACTIVITY - Described are compositions and methods relating to the treatment of keratinous fibers and textiles comprising such fibers with enzymatically-generated peracids in aqueous media. The treatment has beneficial effects, including reducing felting, increasing dye uptake, and reducing prickling tendency. | 05-09-2013 |
20140259452 | ENZYMATIC TEXTILE BLEACHING COMPOSITIONS AND METHODS OF USE THEREOF - Described are compositions and methods for enzymatic bleaching of textiles. A perhydrolase enzyme is used in combination with an ester substrate and hydrogen peroxide to produce a peracid for textile bleaching. Textiles bleached by the exhibit increased dye uptake, decreased textile damage, and/or bulkier softer handle than textiles bleached by conventional chemical bleaching processes. | 09-18-2014 |
Patent application number | Description | Published |
20090008301 | Methods of Increasing Flotation Rate - Methods of increasing the rate of separating hydrophobic and hydrophilic particles by flotation have been developed. They are based on using appropriate reagents to enhance the hydrophobicity of the particles to be floated, so that they can be more readily collected by the air bubbles used in flotation. The hydrophobicity-enhancing reagents include low HLB surfactants, naturally occurring lipids, modified lipids, and hydrophobic polymers. These methods can greatly increase the rate of flotation for the particles that are usually difficult to float, such as ultrafine particles, coarse particles, middlings, and the particles that do not readily float in the water containing large amounts of ions derived from the particles. In addition, new collectos for the flotation of phosphate minerals are disclosed. | 01-08-2009 |
20120076717 | Separation of Diamond from Gangue Minerals - The present invention relates to a method for separating diamond from gangue minerals. In particular, this method relates to the addition of a first reagent or reagents which contact the diamond in diamond ore slurry to at least partially remove hydrophilic coatings from the diamond surfaces. A second reagent or reagents may also be added to the slurry so that the reagent may adsorb on the diamond surfaces and thereby enhance the hydrophobicity of diamonds. The increase in hydrophobicity may improve the flotation of diamonds. | 03-29-2012 |
20130111808 | CLEANING AND DEWATERING FINE COAL - Fine coal is cleaned of its mineral matter impurities and dewatered by mixing the aqueous slurry containing both with a hydrophobic liquid, subjecting the mixture to a phase separation. The resulting hydrophobic liquid phase contains coal particles free of surface moisture and droplets of water stabilized by coal particles, while the aqueous phase contains the mineral matter. By separating the entrained water droplets from the coal particles mechanically, a clean coal product of substantially reduced mineral matter and moisture contents is obtained. The spent hydrophobic liquid is separated from the clean coal product and recycled. The process can also be used to separate one type of hydrophilic particles from another by selectively hydrophobizing one. | 05-09-2013 |
20130340328 | METHOD OF SEPARATING AND DE-WATERING FINE PARTICLES - A process for cleaning and dewatering hydrophobic particulate materials is presented. The process is performed in two steps: 1) agglomeration of the hydrophobic particles in a first hydrophobic liquid/aqueous mixture; followed by 2) dispersion of the agglomerates in a second hydrophobic liquid to release the water trapped within the agglomerates along with the entrained hydrophilic particles. | 12-26-2013 |
20140001103 | Flotation Machine Rotor | 01-02-2014 |
Patent application number | Description | Published |
20100152749 | Table-mounted surgical instrument stabilizers with single-handed or voice activated maneuverability - A surgical instrument stabilizer system for securely holding virtually any instrument during any procedure, delivering vacuum when applicable, and yet allowing easy single-handed or voice activated repositioning by a user. The system utilizes opposing horizontal side-rails mounted to opposing sides of a surgical table, and opposing arms each slidably mounted on a side rail for global lengthwise positioning along the side rails. The arms carry a transverse beam at the foot of the operating table, and a flexible arm is movably mounted on the beam for global lengthwise positioning along the beam. Alternately, the flexible arm may be affixed directly to one of the existing horizontal side rails. The flexible arm leads to an instrument-supporting hand piece pivotally mounted for angular orientation of an instrument supported thereby. The flexible arm can be freely articulated to any position and locked in place. Thus, a supported instrument can be repositioned quickly and easily by single-handed or voice activated manipulation by a surgeon or surgical assistant, and locked in any position up and down along a vertical axis, forward and back, i.e, toward or away from the patient, and rotationally. | 06-17-2010 |
20100179575 | Adjustable sacral mesh fixation device and method - A sacral mesh fixation device and method of use for sacral colpopexy. The sacral mesh fixation device comprises multiple hinged sections pivoted together at opposite ends and adapted to clamp one or more strips of sacral mesh there between. A latching mechanism is provided for releasably latching the opposing sections shut, thereby releasably clamping the sacral mesh to allow verification of tension. A sequential latching mechanism is provided to fixedly lock the fixation device to the sacral mesh by latching the remaining section to the prior sections. At least one of the sections may be sutured to tissue and the sacral mesh inserted between the sections and releasably clamped in place, thereby releasably affixing the mesh to the tissue or fixedly locking the mesh to the device thereby permanently locking the mesh to the tissue. To use the device, a single mesh fixation device or a plurality of mesh fixation devices may be introduced through a trocar into the abdomen, positioned in a single or supporting array, and sutured to surrounding tissue. The sacral mesh is then clamped between opposing sections of the mesh fixation device(s), thereby temporarily suspending the mesh in a sling. However, the fixation devices can be reopened to facilitate easy readjustment and repositioning of the mesh sling to achieve the proper tension and position or fixedly locked for permanent support of the mesh. | 07-15-2010 |
20110174313 | ENDOSCOPIC MESH DELIVERY SYSTEM WITH INTEGRAL MESH STABILIZER AND VAGINAL PROBE - A mesh delivery system for sacral colpopexy procedures is disclosed. The system uses a mesh stabilizer ( | 07-21-2011 |
20140018610 | ENDOSCOPIC MESH DELIVERY SYSTEM WITH INTEGRAL MESH STABILIZER AND VAGINAL PROBE - A mesh delivery system for sacral colpopexy and other procedures involving surgical mesh is disclosed. The system uses a mesh stabilizer ( | 01-16-2014 |
20150020637 | Table-Mounted Surgical Instrument Stabilizers - A surgical instrument stabilizer system that includes an articulating boom that is releasably connectable to a surgical table side rail. The articulating boom includes an actuator, a multi-directional flexible arm having a first end region attached to the actuator, and a cable extending through the flexible arm. The cable has one end region connected to the actuator and another end region connected to a preload tensioning mechanism. The actuator is operable to tighten and loosen the cable, and the preload tensioning mechanism maintains an amount of tension in the cable when the actuator loosens the cable. The system further includes a surgical instrument-supporting member that is attached to a second end region of the flexible arm and is configured to releasably retain a surgical instrument. | 01-22-2015 |
20150051442 | ENDOSCOPIC MESH DELIVERY SYSTEM WITH INTEGRAL MESH STABILIZER AND VAGINAL PROBE - A mesh delivery system for sacral colpopexy procedures is disclosed. The system uses a mesh stabilizer that is introduced in a compressed configuration through a surgical port into the abdomen, and a vaginal probe (inserted through the vagina) with a magnetic or non-magnetic head that engages with the mesh stabilizer, anchoring it in position. The mesh stabilizer employs a pseudoelastic shape memory alloy, and folds compact to deliver multiple mesh straps or a single Y-shaped surgical mesh in a streamlined configuration into the abdomen for facilitating the sacral colpopexy procedure. After delivery, the stabilizer expands to a functional configuration where it interfaces with the probe head and stabilizes and adjustably feeds the mesh strap(s) for suturing while maintaining stabilization of the mesh on the vaginal apex and while keeping excess mesh from obscuring the surgeons view. After suturing, the stabilizer can be removed back through the surgical port. | 02-19-2015 |
Patent application number | Description | Published |
20110060330 | MAGNETIC SWITCHING DEVICE - A magnetic switching device includes an electromagnetic component adapted to be arranged proximate to an exterior surface of an object having a magnetically-switchable device therein and a control circuit electrically connected to the electromagnetic component. The electromagnetic component is constructed to generate a magnetic field of sufficient strength and orientation to engage a switch in the magnetically-switchable device. The invention further includes an electrocautery system, including an electrocautery device, a control circuit electrically connected to the electrocautery device, and an electromagnetic component electrically connected to the control circuit. The electromagnetic component is adapted to be arranged proximate to an exterior surface of an object having a magnetically-switchable device therein. Operation of the electrocautery device causes the electromagnetic component to generate a magnetic field of sufficient strength to engage a switch in the magnetically-switchable device. | 03-10-2011 |
20110101533 | INTEGRATED (MULTILAYER) CIRCUITS AND PROCESS OF PRODUCING THE SAME - A process of forming a semiconductor integrated circuit that includes the steps of: forming at least a first element having a first pattern of conductive material and including a polymer layer surrounding the conductive material, forming at least a second element having a second pattern of conductive material and including a polymer layer surrounding the conductive material, positioning the first element relative to the second element, and bonding the polymer layer of the first and second elements at a temperature below a melting temperature of the conductive materials of the first and second elements wherein the conductive material of the first element contacts the conductive material of the second element and is maintained in position by the bonded polymer layers. | 05-05-2011 |
20110101827 | ENERGY HARVESTING DEVICE - The present invention discloses an energy harvesting device that converts small magnitude and low frequency vibrations into electrical energy. The device can include a base, a low frequency element, and a piezoelectric element. The low frequency element can be movably attached to the base and the piezoelectric element can also be attached to the base and be spaced apart from the low frequency element with a vacant space therebetween. Upon vibration of the low frequency element resulting from environmental vibrations, the low frequency element can impact the piezoelectric element and cause elastic deformation thereto. | 05-05-2011 |
20110241196 | COMPLIANT SPRING INTERPOSER FOR WAFER LEVEL THREE DIMENSIONAL (3D) INTEGRATION AND METHOD OF MANUFACTURING - The present invention is an apparatus for integrating multiple devices. The apparatus includes a substrate having a first via and a second via, a semiconductor chip positioned on a top portion of the substrate and positioned between the first via and the second via, first and second bumps positioned on the semiconductor chip, and an interposer wafer having a first interposer spring assembly and a second interposer spring assembly, the first interposer spring assembly having a first interposer spring and a first electrical connection attached to the first interposer spring, and the second interposer spring assembly having a second interposer spring and a second electrical connection attached to the second interposer spring. | 10-06-2011 |
20120193776 | COMPLIANT SPRING INTERPOSER FOR WAFER LEVEL THREE DIMENSIONAL (3D) INTEGRATION AND METHOD OF MANUFACTURING - The present invention is an apparatus for integrating multiple devices. The apparatus includes a substrate having a first via and a second via, a semiconductor chip positioned on a top portion of the substrate and positioned between the first via and the second via, first and second bumps positioned on the semiconductor chip, and an interposer wafer having a first interposer spring assembly and a second interposer spring assembly, the first interposer spring assembly having a first interposer spring and a first electrical connection attached to the first interposer spring, and the second interposer spring assembly having a second interposer spring and a second electrical connection attached to the second interposer spring. | 08-02-2012 |
20120325539 | BONDING AREA DESIGN FOR TRANSIENT LIQUID PHASE BONDING PROCESS - Devices, methods and systems are disclosed herein to describe the wettability characteristics of the material forming a bonding area, a non-bonding area, and a melted bonding material. The melted bonding material may have a high degree of cohesion and may result in a very high contact angle (e.g., between | 12-27-2012 |
20130270326 | ALLOY FORMATION CONTROL OF TRANSIENT LIQUID PHASE BONDING - A bonding structure enabling fast and reliable methods to fabricate a substantially homogeneous bondline with reduced dependency of a thickness limitation is disclosed. Also, this system creates a bondline targeted for performance in power electronics. This system is highly adaptable as various structures and fabrication options may be implemented. This enables diverse fabrication selection and creates less dependency on outside conditions. The disclosed system is at least applicable to wafer-to-wafer, die-to-wafer, die-to-substrate, or die-to-die bonding. | 10-17-2013 |
20130270327 | IMPROVEMENTS OF LONG TERM BONDLINE RELIABILITY OF POWER ELECTRONICS OPERATING AT HIGH TEMPERATURES - Alloy formation systems and methods and a mechanism, strategy and design for power electronics having high operating temperatures. The system creates a bondline targeted for performance in power electronics. The system provides for sequential alloy growth in high temperature operating power electronics. The system is at least applicable to wafer-to-wafer, die-to-wafer, die-to-substrate, or die-to-die bonding. | 10-17-2013 |
20140097501 | INTEGRATED POWER MODULE FOR MULTI-DEVICE PARALLEL OPERATION - An integrated power module having a dielectric substrate, a source conductor trace formed on the dielectric substrate, a drain conductor trace formed on the dielectric substrate, a gate conductor trace formed on the dielectric substrate, a transistor chip having a top surface and a bottom surface connected to the drain conductor trace, a back-contact resistor having a flat planar structure with a top surface and a bottom surface connected to the gate conductor trace, and a first wire bond connecting the top surface of the transistor chip to the top surface of the back-contact resistor. | 04-10-2014 |
20140104790 | Power Modules and Power Module Arrays Having a Modular Design - Power modules and power module arrays are disclosed. In one embodiment, a power module includes a module support, a high temperature module, and a module cap. The module support includes a frame member, a heat spreader, a first electrically conductive rail, and a second electrically conductive rail. The high temperature module includes a module substrate, a semiconductor device thermally and/or electrically coupled to a semiconductor surface of the module substrate, a first external connector, and a second external connector. The first and second electrically conductive rails are disposed within a through-hole of the first and second external connectors, respectively. The module cap includes a body portion, a plurality of posts, a first opening, and a second opening. The plurality of posts presses against at least the first external connector, the second external connector, and the module substrate such that the high temperature module is thermally coupled to the heat spreader. | 04-17-2014 |
20140346660 | POWER ELECTRONICS DEVICES HAVING THERMAL STRESS REDUCTION ELEMENTS - Power electronics devices having thermal stress reduction elements are disclosed. A power electronics device includes a heat source having a heat source perimeter, a first conduction member coupled to the heat source, and a substrate coupled to the first conduction member. The first conduction member includes a support portion that extends to at least the heat source perimeter and a plurality of finger portions extending from the support portion and separated from one another by web regions, where the plurality of finger portions have a finger thickness that is greater than a web thickness of the web regions. | 11-27-2014 |
20140362537 | Power Modules and Power Module Arrays Having A Modular Design - Power modules and power module arrays are disclosed. In one embodiment, a power module includes a module support, a high temperature module, and a module cap. The module support includes a frame member, a heat spreader, a first electrically conductive rail, and a second electrically conductive rail. The high temperature module includes a module substrate, a semiconductor device thermally and/or electrically coupled to a semiconductor surface of the module substrate, a first external connector, and a second external connector. The first and second electrically conductive rails are disposed within a through-hole of the first and second external connectors, respectively. The module cap includes a body portion, a plurality of posts, a first opening, and a second opening. The plurality of posts presses against at least the first external connector, the second external connector, and the module substrate such that the high temperature module is thermally coupled to the heat spreader. | 12-11-2014 |
Patent application number | Description | Published |
20110213610 | Processor Implemented Systems and Methods for Measuring Syntactic Complexity on Spontaneous Non-Native Speech Data by Using Structural Event Detection - Systems and methods are provided for providing a score for a spontaneous non-native speech response to a prompt. A transcription of the spontaneous speech response is accessed. A plurality of clauses are identified within the spontaneous speech response, where identifying a clause includes identifying a beginning boundary and an end boundary of the clause in the spontaneous speech response. A plurality of disfluencies in the spontaneous speech response is identified. One or more proficiency metrics are calculated based on the plurality of identified clauses and the plurality of the identified disfluencies, and a score for the spontaneous speech response is generated based on the one or more proficiency metrics. | 09-01-2011 |
20110270612 | Computer-Implemented Systems and Methods for Estimating Word Accuracy for Automatic Speech Recognition - Systems and methods are provided for scoring non-native, spontaneous speech. A spontaneous speech sample is received, where the sample is of spontaneous speech spoken by a non-native speaker. Automatic speech recognition is performed on the sample using an automatic speech recognition system to generate a transcript of the sample, where a speech recognizer metric is determined by the automatic speech recognition system. A word accuracy rate estimate is determined for the transcript of the sample generated by the automatic speech recognition system based on the speech recognizer metric. The spontaneous speech sample is scored using a preferred scoring model when the word accuracy rate estimate satisfies a threshold, and the spontaneous speech sample is scored using an alternate scoring model when the word accuracy rate estimate fails to satisfy the threshold. | 11-03-2011 |
20120323573 | Non-Scorable Response Filters For Speech Scoring Systems - A method for scoring non-native speech includes receiving a speech sample spoken by a non-native speaker and performing automatic speech recognition and metric extraction on the speech sample to generate a transcript of the speech sample and a speech metric associated with the speech sample. The method further includes determining whether the speech sample is scorable or non-scorable based upon the transcript and speech metric, where the determination is based on an audio quality of the speech sample, an amount of speech of the speech sample, a degree to which the speech sample is off-topic, whether the speech sample includes speech from an incorrect language, or whether the speech sample includes plagiarized material. When the sample is determined to be non-scorable, an indication of non-scorability is associated with the speech sample. When the sample is determined to be scorable, the sample is provided to a scoring model for scoring. | 12-20-2012 |
20130030808 | Computer-Implemented Systems and Methods for Scoring Concatenated Speech Responses - Systems and methods are provided for scoring non-native speech. Two or more speech samples are received, where each of the samples are of speech spoken by a non-native speaker, and where each of the samples are spoken in response to distinct prompts. The two or more samples are concatenated to generate a concatenated response for the non-native speaker, where the concatenated response is based on the two or more speech samples that were elicited using the distinct prompts. A concatenated speech proficiency metric is computed based on the concatenated response, and the concatenated speech proficiency metric is provided to a scoring model, where the scoring model generates a speaking score based on the concatenated speech metric. | 01-31-2013 |
20130185057 | Computer-Implemented Systems and Methods for Scoring of Spoken Responses Based on Part of Speech Patterns - Systems and methods are provided for scoring a speech sample. Automatic speech recognition is performed on the speech sample using an automatic speech recognition system to generate a transcription of the sample. Words in the transcription are associated with parts of speech, and part of speech sequences are extracted from the parts of speech associations. A grammar metric is generated based on the part of speech sequences, and the speech sample is scored based on the grammar metric. | 07-18-2013 |
20140141392 | Systems and Methods for Evaluating Difficulty of Spoken Text - Systems and methods are provided for assigning a difficulty score to a speech sample. Speech recognition is performed on a digitized version of the speech sample using an acoustic model to generate word hypotheses for the speech sample. Time alignment is performed between the speech sample and the word hypotheses to associate the word hypotheses with corresponding sounds of the speech sample. A first difficulty measure is determined based on the word hypotheses, and a second difficulty measure is determined based on acoustic features of the speech sample. A difficulty score for the speech sample is generated based on the first difficulty measure and the second difficulty measure. | 05-22-2014 |
Patent application number | Description | Published |
20110197423 | DEVICE AND METHOD FOR STORAGE TANK RESTRAINT ON A VEHICLE - A restraint device and method for securing an ammonia storage tank holder to a frame is disclosed. The restraint device includes first and second supports which sandwich about the holder in a parallel fashion. A connecting support attaches to and holds the first and second supports in a substantially parallel relationship about the storage tank holder, and is adjustable such that the second support is selectively movable to expand the perimeter of the holding space. The disclosed method includes the steps of affixing a first support having first and second ends to a frame of a vehicle, placing a storage tank holder into contact with at least one surface of the first support, placing a second support having first and second ends substantially parallel to the first support in contact with a surface of the storage tank holder opposite the first support, and securing the first and second supports. | 08-18-2011 |
20120011830 | METHOD FOR HEATING SOLID AMMONIA TO RELEASE GASEOUS AMMONIA IN EXHAUST AFTERTREATMENT SYSTEM - A method for heating solid ammonia (NH | 01-19-2012 |
20120247089 | INSULATED MAIN NH3 CARTRIDGE SYSTEM WITH SEPARATE START-UP UNIT - A system and method relate to a reductant dosing for use in the reduction of NOx in an exhaust stream is disclosed. The system and method incorporates a separate first or start-up cartridge and an insulated mantel or housing containing at least one to a plurality of main cartridges. The first and main cartridges store an ammonia adsorbing/desorbing material, which releases ammonia gas upon application of sufficient heat. The start-up cartridge permits the initial release of ammonia gas into the exhaust stream even during start-up of an engine, and because it is separate from the main cartridge, the first cartridge cools faster than the main cartridge and can be replenished with ammonia sooner than the main cartridge. The start-up cartridge is housed in or surrounded by a non-insulating debris shield. | 10-04-2012 |
20140021194 | MAIN CARTRIDGE HEATING JACKET - A heating jacket for use with an ammonia-containing storage cartridge for the controlled release of ammonia into an exhaust stream for the reduction of NO | 01-23-2014 |
20140369898 | CROSS STYLE (4 PORT) AMMONIA GAS INJECTOR - An ammonia (reductant) injector for delivering a ammonia into an engine exhaust stream is disclosed. Generally speaking, the injector has a body with an inlet fluidly coupled to a plurality of channels within the body, a plurality of discharge ports, each port being fluidly coupled to at least one channel, and an ammonia feed line connected to the inlet of the body. The plurality of discharge ports are preferably spaced one from another such as to optimize the dispersion of ammonia from the ports throughout a cross-sectional portion of an engine exhaust stream. | 12-18-2014 |
Patent application number | Description | Published |
20110300347 | Fabrication of Patterned Nanofibers - Various methods and systems are provided for the fabrication of patterned nanofibers. In one embodiment, a method includes generating a layer of electrospun nanofibers from a polymer solution and patterning the layer of electrospun nanofibers using ultraviolet (UV) lithography. The patterned electrospun nanofibers may then be thermally treated to form patterned carbon nanofibers. In another embodiment, a device includes a layer of patterned carbon nanofibers formed by generating electrospun nanofibers from a polymer solution, patterning the electrospun nanofibers using UV lithography, and converting the patterned electrospun nanofibers into patterned carbon nanofibers using a thermal treatment. In another embodiment, a method includes depositing electrospun nanofibers for a first predefined period of time, dissipating charge on the deposited electrospun nanofibers for a second predefined period of time where no electrospun nanofibers are deposited, and sequentially repeating the depositing and dissipating steps to from a layer of electrospun nanofibers having a predefined thickness. | 12-08-2011 |
20140124131 | FABRICATION OF NANOPOROUS MEMBRANE - Various methods and systems are provided for fabrication of nanoporous membranes. In one embodiment, among others, a system includes electrode pairs including substantially parallel electrodes, a controllable power supply to control the electrical potential of each of the electrode pairs, and a syringe to eject an electrically charged solution from a needle to form a nanofiber. The orientation of the nanofiber in a nanofiber layer is determined by the electrical potentials of the electrode pairs. In another embodiment, a method includes providing a nanoporous membrane including nanofiber layers between a transferor and a mainmold of a stamp-through-mold (STM) where adjacent nanofiber layers are approximately aligned in different directions. A patterned membrane is sheared from the nanoporous membrane using the transferor and the mainmold of the STM and transferred to a substrate. | 05-08-2014 |
20140139385 | FOLDED PATCH ANTENNA PLATFORM - Various systems and methods are provided for folded patch antennas. In one embodiment, among others, a folded patch antenna includes a patch disposed on an outer side of a flexible substrate and a ground plane disposed on an inner side of the flexible substrate opposite the patch. The flexible substrate is folded to form an enclosed cavity defined by the inner side of the flexible substrate. The ground plane may provide electromagnetic interference (EMI) shielding of the cavity. In another embodiment, among others, a folded patch antenna platform includes a flexible substrate, a folded patch antenna, and a transceiver mounted on the flexible substrate. The folded patch antenna includes a patch communicatively coupled to the transceiver and a ground plane, which are disposed on opposite sides of the flexible substrate. | 05-22-2014 |
20140248574 | MULTIFUNCTIONAL ORAL PROSTHETIC SYSTEM - Various methods and systems are provided for multifunctional denture systems. In one example, among others, a multifunctional oral prosthetic system includes an oral prosthetic device that may be located in an oral cavity. The oral prosthetic device includes a plurality of sensors and an internal module in communication with the plurality of sensors. The internal module is configured to provide sensor data corresponding to at least one of the plurality of sensors to an external processing unit when located in an oral cavity. | 09-04-2014 |
Patent application number | Description | Published |
20110064263 | Method and system for processing an image received from a remote source - In a first exemplary embodiment of the present invention, an automated, computerized method is provided for processing an image. According to a feature of the present invention, the method comprises the steps of, at a computer system, receiving an image recorded at and transmitted from a remote source, at the computer system, processing the transmitted image, for segregation of the transmitted image into a corresponding intrinsic image and, at the computer system, processing the corresponding intrinsic image to perform a preselected task, for a result. As a further feature of the first exemplary embodiment of the present invention, the remote source comprises a cell phone or remote computer system. | 03-17-2011 |
20110150338 | Method and system for generating intrinsic images using single reflectance technique - In a first exemplary embodiment of the present invention, an automated, computerized method is provided for processing an image. According to a feature of the present invention, the method comprises the steps of providing an image file depicting an image, in a computer memory, identifying a dominant region of single reflectance in the image and segregating the image into intrinsic images as a function of the dominant region of single reflectance. | 06-23-2011 |
20110170768 | Image segregation system with method for handling textures - In a first exemplary embodiment of the present invention, an automated, computerized method is provided for processing an image. According to a feature of the present invention, the method comprises the steps of providing an image file depicting an image, in a computer memory, assembling a feature vector for the image file, the feature vector containing information regarding a likelihood that a selected pair of regions of the image file are of a same intrinsic characteristic, for example, a same texture, providing a classifier derived from a computer learning technique, computing a classification score for the selected pair of regions of the image file, as a function of the feature vector and the classifier and classifying the regions as being of the same intrinsic characteristic, as a function of the classification score. | 07-14-2011 |
20130136348 | METHOD AND SYSTEM FOR GENERATING INTRINSIC IMAGES USING A SINGLE REFLECTANCE TECHNIQUE - An automated, computerized method is provided for processing an image. The method includes the steps of providing an image file depicting an image, in a computer memory, identifying a dominant region of single reflectance in the image and segregating the image into intrinsic images as a function of the dominant region of single reflectance. | 05-30-2013 |
Patent application number | Description | Published |
20100119490 | Therapeutic Use of CD31 Expressing Cells - As described below, the present invention features compositions and methods related to the isolation, culture and therapeutic use of CD31-expressing cells. | 05-13-2010 |
20140294764 | COMPOUNDS AND COMPOSITIONS USED TO EPIGENETICALLY TRANSFORM CELLS AND METHODS RELATED THERETO - This disclosure relates to compounds, compositions and methods of epigenetically transforming cells. In certain embodiments, the disclosure relates to methods of generating epigenetically altered cells comprising mixing isolated cells with compositions disclosed herein under conditions such that epigenetically altered cells are formed. In certain embodiments, the disclosure contemplates inducing cells, such as adult somatic cells or cells that are not naturally pluripotent, into cells with chemically induce pluripotency. In certain embodiments, the disclosure contemplates certain compounds disclosed herein, compounds disclosed herein optionally substituted with one or more substituents, derivatives, or salts thereof, for these purposes. | 10-02-2014 |
20140335606 | PURIFICATION OF STEM CELL-DERIVED CARDIOMYOCYTES USING MOLECULAR BEACONS TARGETING CARDIOMYOCYTE SPECIFIC mRNA - This disclosure is in the area of research and therapeutics. In certain embodiments, it provides methods to assist in the purification of cell mixtures, e.g., cardiomyocytes, using molecular beacons targeting cell-type specific RNA, e.g. mRNA. | 11-13-2014 |
20150072420 | THERAPEUTIC USE OF CD31 EXPRESSING CELLS - As described below, the present invention features compositions and methods related to the isolation, culture and therapeutic use of CD31-expressing cells. | 03-12-2015 |