Patent application number | Description | Published |
20090215122 | Process for Producing Thioredoxin - An object of the present invention is to provide a process for conveniently and efficiently producing high purity thioredoxin from yeast. | 08-27-2009 |
20090280100 | Preventive or Therapeutic Agent for Inflammatory Ocular-Surface Diseases - [Problems] The present invention aims to provide a preventive or therapeutic agent for inflammatory ocular-surface diseases. | 11-12-2009 |
20100021431 | Agent for Promoting the Production of Thioredoxin - A novel pharmaceutical application of an extract from a vaccine virus-inoculated and inflamed tissue and relates to a thioredoxin production promoting agent containing the extract as an active ingredient. The extract has an excellent thioredoxin production promoting action against an oxidative stress caused by a stimulus by such as a tobacco smoke extract or hydrogen peroxide and showed a significant lung cell protective effect. Therefore, the pharmaceutical of the invention containing the extract as an active ingredient is highly useful as a preventive or therapeutic agent for a chronic obstructive lung disease considered to be mainly caused by a continuous oxidative stress such as chronic smoking and the pharmaceutical with less side effects and high safety. | 01-28-2010 |
20120003673 | Screening method, composition containing substance selected by the screening method, and binding substance - Disclosed is a screening method which can select a substance having an influence on the binding between thioredoxin and MIF. The screening method is characterized in that a test substance capable of enhancing the binding between a polypeptide belonging to the thioredoxin family and a macrophage migration inhibitory factor is selected through the steps of mixing at least one binding substance selected from the substances (1) to (4) shown below with the test substance, allowing the binding substance to bind to the macrophage migration inhibitory factor, and confirming the binding between the binding substance and the macrophage migration inhibitory factor: (1) a polypeptide belonging to the thioredoxin family; (2) a protein which comprises an amino acid sequence produced by deleting, substituting or adding one or several amino acid residues in an amino acid sequence for a polypeptide belonging to the thioredoxin family and has the same activity as that of a polypeptide belonging to the thioredoxin family; (3) a gene encoding the polypeptide (1); and (4) a gene encoding the protein (2). | 01-05-2012 |
20130072441 | Protease Inhibitors and Preventives or Remedies for Disease | 03-21-2013 |