Yeatman
Dennis Yeatman, San Diego, CA US
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20080245684 | Toiletry & Sundries Attachment And Containment Device - Provided is an toiletry and sundries attachment and containment device for interfacing a container or other containment means with a tissue dispensing apparatus found in public and private restrooms. The device includes one or more tabs for attaching to the container, and for attaching the container to the tissue dispensing apparatus. The tabs may be rigid, semi-rigid or flexible, and may be manufactured from a variety of materials including paper, plastic and metal. The attachment mechanisms or schemes may be any of a number of attachment mechanisms to include: mechanical fasteners, glue, Velcro®, adhesives strips, tape, etc. The container may be permanently or removably attached to the tabs, and hence the tissue dispensing apparatus, and may contain tissues, wet wipes, soaps, as well as other toiletries and sundries for use in a restroom. | 10-09-2008 |
Dennis Francis Yeatman, San Diego, CA US
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20140302949 | Goalie Stand - Provided is a device for use by athletic teams, participants, and recreational groups for positioning in or in front of a goal to replicate a person acting as a goalie or defender. The device or “goalie stand” is durable, portable, mobile, and easily transportable for ease of use and movement or relocation. The goalie stand may be adjusted such that the height or width may be increased or decreased depending on the user's preference. The goalie stand may be a single continuous construction, or it may consist of two or more sections that are joined together by any one of a number of mechanical fastening means. The goalie stand may have adjustable components, such as a stick or arm, that can be positioned at various angles relative to the body of the stand. The goalie stand may be used on any surface, such as grass, dirt, artificial turf, or ice. | 10-09-2014 |
Eric Yeatman, London GB
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20090090197 | Pre-concentrator and sample interface - This invention describes a multi-stage pre-concentrator device for use with a detector system. One pre-concentrator stage is detachable and may be used to collect sample remotely from the detection system. The detachable pre-concentrator stage mates with the detector system and can transfer its desorbed sample to another pre-concentrator stage which also incorporates the functions of a sample loop serving as an injection volume to the separation column of an analytical instrument. In one embodiment the fixed pre-concentrator stage serves as a sample loop that preferably integrates suitable valves with sorbent materials onto the same structure to minimise dead volume, maximise sensitivity, improving column loading efficiency, reducing duty cycles and minimising detection system response time. | 04-09-2009 |
20110127423 | Mass Spectrometer System - This invention describes an analytical system where a kinetic impact ionisation source is combined with an RF—only ion guide to form a mass spectrometer system for analysis of the elemental and chemical composition of exoatmospheric particles. The kinetic impact ionisation source may be used to transform a flux of particle debris into a beam of ions for analysis by a mass analyzer. | 06-02-2011 |
Eric Morgan Yeatman, London GB
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20150084482 | POWER GENERATION DEVICE - A device able to generate electrical power through relative rotational motion of first ( | 03-26-2015 |
Timothy Yeatman, Thonotosassa, FL US
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20100240540 | GENOTYPIC TUMOR PROGRESSION CLASSIFIER AND PREDICTOR - Actively dividing tumors appear to progress to a life threatening condition more rapidly than slowly dividing tumors. Assessing actively dividing tumors currently involves a manual assessment of the number of mitotic cells in a histological slide prepared from the tumor and assessed by a trained pathologist. Disclosed is a method for using cumulative information from a series of expressed genes to determine tumor prognosis. This cumulative information can be used to categorize tumor samples into high mitotic states or low mitotic states using a mathematical algorithm and gene expression data derived from microarrays or quantitative-Polymerase Chain Reaction (Q-PCR) data. The specific mathematical description outlines how the algorithm assesses the most informative subset of genes from the full list of genes during the assessment of each sample. | 09-23-2010 |
20110046002 | Seven Gene Breast Cancer Predictor - The invention provides a molecular marker set that can be used for prognosis of breast cancer in a patient using histologically normal tissue. The invention also provides methods for evaluating prognosis of breast cancer in a patient based on a molecular molecular signature. | 02-24-2011 |
20130172203 | HYBRID MODEL FOR THE CLASSIFICATION OF CARCINOMA SUBTYPES - A two-tiered classification system that can be integrated with the current algorithm used by pathologists for identification of the site of origin for ‘malignancy with unknown primary ’ is presented. In use, morphology, immunohistochemical (IHC) studies, and microarry-based top tier gene expression classifiers first subclassify cytokeratin positive carcinomas into adenocarcinoma, squamous cell carcinoma, neuroendocrine carcinoma and urothelial carcinoma. Subsequently, organ-specific IHC-markers, if available, are used in conjunction with microarray-based second tier gene expression classifiers to assign the primary site of origin to the sample. This new hybrid approach combines IHC with a hierarchy of quantitative gene expression based classifiers into an algorithmic method that can assist pathologists to further refine and support their decision making process. | 07-04-2013 |
Timothy Yeatman, Thonotasassa, FL US
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20110288890 | COMPUTER SYSTEMS AND METHODS FOR SELECTING SUBJECTS FOR CLINICAL TRIALS - Computers, computer program products, and methods for identifying a plurality of subjects for a clinical trial are provided. A candidate set of molecular profiles in a stored plurality of molecular profiles are identified. Each such profile has measurements for a discriminating set of cellular constituents that match the measurements of corresponding cellular constituents in a responder set of biological samples, thereby identifying the plurality of subjects for the trial from those subjects from which the candidate set of molecular profiles were derived. Each respective molecular profile in the stored plurality of profiles has measurements of a plurality of cellular constituents from a respective biological sample in a plurality of samples obtained from a first plurality of subjects. The discriminating set of cellular constituents is identified from those cellular constituents in the plurality of cellular constituents whose measurement values discriminates between the responder and nonresponder sets of biological samples. | 11-24-2011 |
Timothy Yeatman, Greenville, SC US
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20140031251 | METHODS OF CLASSIFYING HUMAN SUBJECTS WITH REGARD TO CANCER PROGNOSIS - In one aspect, methods, markers, and expression signatures are disclosed for assessing the degree to which a cell sample has epithelial cell-like properties or mesenchymal cell-like properties. In another aspect, methods are provided for predicting cancer patient prognosis based on whether the cancer is classified as having a high or low EMT Signature Score. | 01-30-2014 |
Timothy J. Yeatman, Spartanburg, SC US
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20150160223 | METHOD OF PREDICTING NON-RESPONSE TO FIRST LINE CHEMOTHERAPY - The invention provides a method for determining a prognosis of colorectal cancer in a colorectal cancer patient, comprising classifying said patient as having a good prognosis or a poor prognosis using measurements of a plurality of gene products in a cell sample taken from said patient, said gene products being respectively products of at least 1 of the genes listed in Table 1, or respective functional equivalents thereof, wherein said good prognosis predicts a positive response to standard chemotherapy regimens, and said poor prognosis predicts non-responsiveness. Provided herein, the invention includes a gene signature to predict which patients will to benefit from standard colon cancer therapy; alternatively, patients who are classified as non-responders may be more likely to benefit from a novel agent such as a Notch inhibitor. | 06-11-2015 |
Timothy J. Yeatman, Thonotosassa, FL US
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20100184065 | Method of Predicting Non-Response to First Line Chemotherapy - The invention provides a method for determining a prognosis of colorectal cancer in a colorectal cancer patient, comprising classifying said patient as having a good prognosis or a poor prognosis using measurements of a plurality of gene products in a cell sample taken from said patient, said gene products being respectively products of at least 1 of the genes listed in Table 1, or respective functional equivalents thereof, wherein said good prognosis predicts a positive response to standard chemotherapy regimens, and said poor prognosis predicts non-responsiveness. Provided herein, the invention includes a gene signature to predict which patients will to benefit from standard colon cancer therapy; alternatively, patients who are classified as non-responders may be more likely to benefit from a novel agent such as a Notch inhibitor. | 07-22-2010 |
20110039723 | MALIGNANCY-RISK SIGNATURE FROM HISTOLOGICALLY NORMAL BREAST TISSUE - The invention provides for malignancy-risk gene signatures that predict the risk of developing breast cancer, the recurrence of breast cancer, and/or the metastasis of breast cancer. These signatures have numerous clinical applications including assessing risk of breast cancer development following routine breast biopsy, assessing the need for adjuvant radiotherapy after lumpectomy, and determining the need for completion mastectomy following lumpectomy for the breast cancer patient and other treatment plans that are personalized for the patient. | 02-17-2011 |
20130034540 | Immune Gene Signatures in Cancer - This invention relates to methods for selecting a treatment, treating, and predicting survival time in subjects with cancer, such as colorectal cancer, based on tumor expression levels of chemokines, cytotoxic genes, and/or dendritic cell genes. | 02-07-2013 |
Timothy J. Yeatman, Tampa, FL US
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20110106740 | TISSUE CLASSIFICATION METHOD FOR DIAGNOSIS AND TREATMENT OF TUMORS - The present invention discloses an informational computation method for classifying objects Specifically, the invention is a system, method, and computer-readable media for classifying tumors using a nonparametric statistical classifier in conjunction with an artificial neural network. The invention classifies unknown tumor types based on the correlation of unknown tumor's genetic expression compared to the genetic expression of know tumor types by first performing a nonparametric statistical analysis on the know data, training a artificial neural network with the known data, and then inputting the unknown tumor data into the neural network to calculate the probability that the sample tumor is a member of a class of tumors. By using a statistical classifier in conjunction with a neural network, the invention classifies unknown tumors more accurately then conventionally possible. Advantageously, by using a variety of tumor genetic expression data sets, including both published data sets and generated data sets, a tumor classifier, robust and accurate enough for clinical application, is provided. | 05-05-2011 |