Patent application number | Description | Published |
20090046359 | Microscope - A microscope, in the microscope for observing a sample cultured with a culture vessel, can automatically obtain information about growing conditions of the sample. For this purpose, the microscope is a microscope for observing a sample cultured with a culture vessel, and includes a focusing unit focusing on at least two faces including a first face where the sample exists in the culture vessel and a second face differing from the first face based on predetermined conditions, and an imaging unit imaging for the first face and the second face to create images. | 02-19-2009 |
20090068728 | Cell incubator - A cell incubator having an observation unit to observe a cell incubation process comprises: a focus detecting unit to detect a focus position of an imaging optical system of the observation unit; an optimum focus selecting unit to select an optimum focus position based upon a plurality of images taken by moving the imaging optical system stepwise at a fine pitch along an optical axis direction from the focus position, based upon the focus position detected by the focus detecting unit; and a fluorescence observation unit to shoot a fluorescence image of the cells by moving the imaging optical system to the optimum focus position thus detected by the optimum focus selecting unit. | 03-12-2009 |
20090075365 | Culture Device - A culture device containing a culture vessel for culturing a cell, in which the culture device includes a thermostatic vessel having a stacker containing a plurality of culture vessels for culturing a cell, and an observation portion arranged to be isolated from an atmosphere at inside of the thermostatic vessel and having an object lens, an object lens drive portion, and a camera portion to observe a cell at inside of the culture vessel installed at an observation position at inside of the thermostatic vessel. | 03-19-2009 |
20090081769 | Apparatus for judging cell detachment, method of judging cell detachment, and cell culture apparatus - An apparatus for judging cell detachment that judges a state of detachment of cells that have been cultured within a cell culture container (cultured cells), includes: an image-capturing unit that captures an image of the cultured cells; and a detachment state judging unit that determines luminance information within the cell culture container based upon image capture data from the image-capturing unit, and judges that the culture cells are detached when the luminance information exceeds a predetermined luminance level. | 03-26-2009 |
20090087075 | Observation device - An observation device that observes a test specimen such as cultured cells or the like includes: an illumination device that illuminates the test specimen; an image-capturing device that acquires an image of the test specimen illuminated by the illumination device; a storage unit that stores correlation data manifesting a correlation relationship between an occupation ratio of the test specimen within a culture vessel, and statistically processed data regarding to luminance information of the test specimen; and a calculation unit that obtains the statistically processed data based upon luminance information in a specified color of the test specimen captured by the image-capturing device, and calculates the occupation ratio of the test specimen within the culture vessel using the correlation data in the storage unit. | 04-02-2009 |
20090093046 | Incubation apparatus - An incubation apparatus, including a temperature-controlled room adjusted to be a predetermined environment condition, and incubating a sample of an incubation container inside the temperature-controlled room, includes a carrying apparatus, an imaging section, and an image analyzing section. The carrying apparatus carries the incubation container in the temperature-controlled room. The imaging section photographs a whole of the incubation container inside the temperature-controlled room. The image analyzing section analyses an operation state of the incubation apparatus or an incubating environment state of the sample based on a total observing image of the incubation container photographed at the imaging section, and outputs an error signal notifying an abnormality of the operation state or the incubating environment state in accordance with the analysis result. | 04-09-2009 |
20090154788 | AUTOMATIC SYSTEM FOR JUDGING QUALITY OF CELL - An automatic culture device | 06-18-2009 |
20090273829 | Observing Device - The observing apparatus is being equipped with an image-forming optical system which forms an image of light emitted from a specimen, an imaging unit which picks up the image of the specimen formed by the image-forming optical system, and an illuminating unit which illuminates the specimen with a surface illuminant in which bright areas and dark areas are arranged alternately in order to provide an observing apparatus suitable to observe a transparent specimen with a wide field of view. If the position of the surface illuminant and the pitch of contrasting are set properly, each partial area of the specimen is illuminated obliquely at a small angle by each bright area of the surface illuminant. Therefore, the imaging unit can acquire a dark-field observation image of each partial area. | 11-05-2009 |
20090296208 | Observation device and wavelength limiting filter - An observation device observing a sample cultured in a culture vessel includes an illuminating unit including an illumination optical system and illuminating the sample, an image-capturing unit including an imaging sensor and generating an image by capturing an image of the sample illuminated by the illuminating unit, and a wavelength limiting filter being placed on an optical axis of the illumination optical system and between the illuminating unit and the image-capturing unit, and limiting a part of wavelengths of an illumination light from the illumination optical system in accordance with optical absorption properties of an additive contained in a culture medium used for culturing the sample. Accordingly, it is possible to suppress a change of the image resulting from the additive and to enable to generate an appropriate image in an automatic observation. | 12-03-2009 |
20090317895 | Observation device - An observation device which is provided with an observation optical system and observes a specimen cultured in a culture vessel via the observation optical system includes a moving unit moving the culture vessel to a position where a distortion caused by the observation optical system occurs, an imaging unit imaging the culture vessel to generate an image at the position where the distortion occurs, and a calculating unit calculating a medium volume of a medium in the culture vessel based on the image. | 12-24-2009 |
20100047902 | Transfer device for culture vessel, culture device and holder for culture vessel - A transfer device for a culture vessel for transferring a culture vessel for culturing a cell, a culture device including the transfer device for a culture vessel, and a holder for a culture vessel for holding a culture vessel, in which the transfer device for a culture vessel includes a transferring unit transferring a culture vessel for culturing a cell, an inputting unit inputting a kind of the culture vessel, a speed setting unit setting a transfer speed of the culture vessel based on a kind of the culture vessel inputted to the inputting unit, and a controlling unit controlling a transfer speed of the transferring unit to be the transfer speed set by the speed setting unit. | 02-25-2010 |
20100129849 | CELL OBSERVATION APPARATUS, CELL OBSERVATION METHOD, AND PROGRAM - The present invention relates to a cell observation apparatus that facilitates the setting of schedules. An observation schedule that has already been registered is presented to a user by a time schedule display unit of a schedule setting screen, and a new observation schedule is acquired in response to an input of set values of photographic conditions by the user. Then determination is made whether the photographing time of this observation schedule and the photographing time of the already registered observation schedule overlap, and when the photographing times are determined to overlap, the photographic conditions including the photographing time of one or both of the observation schedules are changed and the observation schedule is registered. The invention can be applied, for example, to incubators for culturing cells. | 05-27-2010 |
20100208340 | OBSERVATION DEVICE - An observation device that limits the brightness of an area to be a background of a sample, so that contrast of the sample can be clearly observed in the reflection observation method. An illumination light quantity limiting stop that is disposed on the emission-side pupil surface of the illumination light has a doughnut shape, by which an opening portion is formed at the center of a disk, so that the peripheral portion of the luminous flux of the illumination light is interrupted and only the center portion thereof is transmitted. An incident light quantity limiting stop that is disposed on the incident-side pupil surface has a circular shape smaller than the cross-section of the luminous flux, so that the center portion of the luminous flux is interrupted, and therefore only the peripheral portion of the luminous flux of the reflected light is transmitted. | 08-19-2010 |
20100208960 | CULTURE APPARATUS, CULTURE INFORMATION MANAGEMENT METHOD, AND COMPUTER READABLE MEDIUM STORING PROGRAM OF SAME - A temperature-controlled room accommodates an incubation container incubating a sample and maintains the inside thereof in a predetermined environment condition. An imaging section generates data of a plurality of observing images. An image analyzing section performs an image analyzing process on the data of the plurality of observing images obtained by imaging the incubation container at different times. Image analyzing data generated by the image analyzing section includes morphological information which indicates incubation states of the samples and rate-of-change information regarding the morphological information. A search processing section conducts a search for the incubation container which meets the first searching condition and the second searching condition based on the image analyzing data. | 08-19-2010 |
20100274798 | Program recording medium, computer, and culture state analyzing method - In one aspect of an embodiment, a computer determines an identity of the cells with a cell shape data, and also determines a correspondence relationship of identification data between a plurality of cell analyzing tables at a different observing times. Also, the computer, based on the correspondence relationship of the identification data, records a plurality of cell analyzing tables at the different observing times in a storage medium by making into a database which can be searched in a direction of a time axis for each of the cells having commonality. | 10-28-2010 |
20100328434 | Microscope apparatus and cell culture apparatus - An imaging section of a microscope apparatus captures a plurality of microscope images each having the focal position which differs in the field being same with a light flux having passed through a microscopic optical system. A region separating section separates a cellular region from a non-cellular region by using the plurality of the microscope images. A focusing position calculating section finds a focusing position in a target pixel included in the cellular region based on a brightness change in the position being same in the plurality of the microscope images. A three dimensional information generating section generates three dimensional information of a cultured cell based on a position of the cellular region and the focusing position in the target pixel. | 12-30-2010 |
20110070631 | Container transportation case and culture treating device - A container transportation case is used to carry in/out a culture container to/from a chamber of a culture treating device. A case body of the container transportation case has a container housing room in which the culture container can be arranged and the container housing room is in communication with the outside by an opening part. A joint unit of the container transportation case can be attached/removed to/from a carrying-in/out opening of the culture treating device, and forms a space that is isolated from an outside atmosphere by joining the container housing room and the carrying-in/out opening. An airtight member of the container transportation case closes the opening part to block the container housing room from the outside atmosphere. | 03-24-2011 |
20120120302 | FOCUS CONTROL METHOD AND CULTURE OBSERVATION APPARATUS - The focus control culture observation apparatus enable simple and reliable detection of a focusing position of an objective lens on a subject and with certainty. When a focusing position is detected, an area, which includes an edge portion of the culture medium drop is selected as an AF area which is to be a target of detecting the focusing position of the objective lens on the culture medium drop. The apparatus detects the focusing position on the culture medium drop based on an observation image of the AF area. By detecting the focusing position as a targeting area that is different from an area which is near the edge of the culture container and where illumination unevenness is generated, the detection accuracy can be improved. | 05-17-2012 |
20120133755 | ORGANISM SAMPLE OBSERVATION DEVICE - A biological specimen observation apparatus whereby observation of a biological specimen can be performed accurately. In macro observation, a biological change region is extracted from a macro image, a micro observation point corresponding to an extracted biological change region is registered, and an object for tracking is identified. In micro observation, it is judged from the micro image whether or not biological change has continued in the biological change region at the micro observation point, and the registered micro observation point is updated on the basis of this judgment result. It is possible to carry out both macro observation for detecting a biological change region and micro observation for observing the progress of growth of a partial minute region where biological change has been exhibited, and to carry out accurate observation of a biological specimen. | 05-31-2012 |
20120194664 | CELL PICKING-ASSISTING DEVICE, DISPLAY DEVICE AND CULTURE CONTAINER - A cell picking support device, a display device and a culture container that can enhance work efficiency. An adapter fixes a well plate that holds cells cultured in a cell culture observation device. A control unit reads culture observation information that includes cell information and coordinate information, from a memory card that is fitted to an external memory I/F. A display unit is provided on a placing surface side of the well plate that is fixed by the adapter, and in response to control by the control unit, displays the cell information, read from the memory card, at display positions corresponding to positions on the bottom face of the well plate, as specified by the coordinate information. Embodiments can be used, for instance, as a cell picking support device that supports a picking operation that is performed in a clean bench. | 08-02-2012 |
20120214150 | STIRRING METHOD, CELL CULTURE METHOD, STIRRING APPARATUS, AND CELL CULTURE APPARATUS - A stirring method includes measuring, with respect to cells which adhere to an inner surface of a culture vessel to be cultured, an ease of peeling between the culture vessel and the cell and an ease of peeling between the mutual cells, and performing a stirring process on the cells in the culture vessel by determining a process content of the stirring process with respect to the cells in the culture vessel, based on the ease of peeling between the culture vessel and the cell and the ease of peeling between the mutual cells. | 08-23-2012 |
20130027539 | CELL OBSERVING APPARATUS AND CELL INTEGRATION METHOD - User's time and labor required for performing manipulations with respect to cells which exist in an incubation container, are reduced. To achieve the above, a cell observing apparatus includes an observation stage supporting an incubation container that houses cells, a micro imaging optical system forming, on an imaging device for micro imaging, an image of the cell in the incubation container disposed at an observing position of the observation stage, a macro imaging optical system forming, on an imaging device for macro imaging, an image of an area wider than that captured by the micro imaging optical system in the incubation container, and a controlling unit controlling an operation of a manipulation needle that manipulates the cells in the incubation container, in which the micro imaging optical system is disposed on a side facing the macro imaging optical system with the observation stage being located therebetween. | 01-31-2013 |