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Yang, MA
Annie Yang, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080200664 | CELL REGULATORY GENES, ENCODED PRODUCTS, AND USES RELATED THERETO - This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotypes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63. | 08-21-2008 |
Che-Liang Yang, Westford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120023241 | SSL Cache Session Selection - In one embodiment, a gateway implements: selecting, from a plurality of instances, an instance with which to begin a secure initial communication session; establishing, with the selected instance, a secure initial communication session; generating information regarding the session, the information including a session identifier associated with the session and an instance identifier associated with the selected instance; receiving a request to resume the session, the request including the session identifier and the instance identifier; using the instance identifier to identify a processing instance from the plurality of instances; and resuming the initial communication session using the identified processing instance, wherein at least a portion of the information associated with the initial communication session is re-used for the resumed session. | 01-26-2012 |
Chen Yang, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090004852 | Nanostructures Containing Metal Semiconductor Compounds - A network element ( | 01-01-2009 |
Chengda Yang, Auburndale, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090237503 | ESTIMATING MOTION OF AN EVENT CAPTURED USING A DIGITAL VIDEO CAMERA - An event aware video system (EAVS) is to capture video frames during a first time period and process events in the video frames before transferring the processed data to a central computing system. The EAVS may establish a present no-event frame from the video frames by marking the last frame as the present no-event frame if the difference between adjacent pair of video frames is less than a threshold value. The EAVS may establish an event frame, wherein a present frame captured after establishing the no-event frame is marked as the event frame if the difference between the present frame and a previous frame is greater than the threshold value. The EAVS may provide event information including motion vectors to a central computing system by performing one-dimensional search on a moving object of the event frame, wherein the motion vectors may represent displacement of objects moving within the moving object. | 09-24-2009 |
| 20090238411 | ESTIMATING MOTION OF AN EVENT CAPTURED USING A DIGITAL VIDEO CAMERA - An event aware video system (EAVS) is to capture video frames during a first time period and process events in the video frames before transferring the processed data to a central computing system. The EAVS may establish a no-event frame by marking a last frame as the no-event frame if the difference between adjacent pair of video frames is less than a threshold value. The EVAS may mark a present frame captured after establishing the no-event frame as the event frame if the difference between the present and a previous frame is greater than the threshold value. The EAVS may provide event information to the central computing system by performing temporal blending, which includes linearly combining the movement of objects within the moving object in adjacent event frames to generate blurred images. The difference between the blurred images may represent displacement of objects moving within the moving object. | 09-24-2009 |
| 20090238542 | CAPTURING EVENT INFORMATION USING A DIGITAL VIDEO CAMERA - An event aware video system (EAVS) is to capture video frames during a first time period and process event portion of the video frames before transferring the processed data to a central computing system. The EAVS may establish a present no-event frame from the video frames, wherein a last frame of the video frames is marked as the present no-event frame if the difference between adjacent pair of frames of the video frames is less than a threshold value. The EVAS may establish an event frame, wherein a present frame captured after establishing the no-event frame is marked as the event frame if the difference between the present frame and a previous frame captured prior to the present frame is greater than the threshold value. The EAVS may generate the processed data by processing the event of the event frame. | 09-24-2009 |
| 20110153798 | Method and apparatus for providing a remotely managed expandable computer system - A remotely managed expandable multi-user computer system is provided. The computer system includes a removable compute cartridge and a removable storage cartridge allowing easy upgrade of the computer system. The computer system self-configures when powered on to allow remote management by another system over a network. Automatic failover support is provided without the need for a separate compute element. A self-configurable removable secure-to-wireless converter to couple to a client computer system allows secure communications between the multi-user system and the client computer system via a wireless network. | 06-23-2011 |
Chen-Lu Yang, Westport, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110046715 | Auxetic Fabric Structures and Related Fabrication Methods - Auxetic fabric structures, of the sort which can be useful in conjunction with composite materials, and related methods of fabrication. | 02-24-2011 |
Dong S. Yang, Quincy, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100145080 | PURIFICATION OF TAXANES - Disclosed is a method of crystallizing a taxane comprising combining the taxane and methylene chloride to obtain a solution and adding an anti-solvent to the solution to obtain a crystalline taxane, wherein the anti-solvent is selected from the group consisting of hexane and heptane. | 06-10-2010 |
Feng Yang, Acton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110059455 | METHODS AND COMPOSITIONS FOR DIRECT CHEMICAL LYSIS - A direct chemical lysis composition includes an assay compatible buffer composition and an assay compatible surfactant. When combined with a specimen storage composition, such compositions prevent undesired modifications to nucleic acid and proteins lysed from cells in the biological sample. Assays of samples from such compositions do not require expensive and time-consuming steps such as centrifugation and prolonged high temperature processing. The direct chemical lysis composition of the present invention permits direct nucleic acid extraction from the cells in the biological sample without the need to decant off the transport media or otherwise exchange the transport media with assay compatible buffers. There is no need to combine the sample with proteinase K or another enzyme to extract nucleic acids from the cells. A method for lysing cells to obtain target nucleic acid for assay and a kit for combining the direct chemical lysis composition with a sample are also contemplated. | 03-10-2011 |
Frank Yang, Framingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090216593 | POINT SOURCE ASSET SYSTEM AND METHOD THEREOF - Embodiments of the present invention relate to a point-source asset system for managing an incentive-based environmentally-conscious behavior program and methods of implementing the same. In one embodiment, a system comprises: an administrative entity, communicably accessible via a computer network, comprising a database; a consumer entity having an entity account stored on the database; an environmentally-conscious sub-program, comprising a point-source asset, associated with the consumer entity; a means for monitoring point-source asset activity within the environmentally-conscious sub-program; and a means for granting a credit value, correlating to the point-source asset activity, to the entity account. | 08-27-2009 |
Frank C. Yang, Framingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080296374 | RECYCLING KIOSK SYSTEM AND METHOD THEREOF - Embodiments of the present invention relate to a system and method of providing incentive to recycle recyclable materials by providing financial incentives to consumers for recycling at a recycling kiosk. In one embodiment, a method of providing incentive to recycle recyclable materials comprises providing a recycling kiosk having a load determining device for receiving a quantity of recyclable materials from at least a first entity, obtaining identification data associated with the first entity, measuring the quantity of recyclable material received by the recycling kiosk, calculating a reward based on a measurement of the quantity of recyclable material disposed at least proximate to the recycling kiosk by the at least one entity, and associating the reward to the at least one entity. | 12-04-2008 |
| 20090014363 | DROP-OFF RECYCLING SYSTEM AND METHOD THEREOF - Embodiments of the present invention relate to a system and method of providing incentive to recycle recyclable materials by providing financial incentives to consumers for recycling at a central drop-off recycling facility. In one embodiment of the present invention, a method of providing incentive to recycle recyclable materials comprises creating an account for at least a first entity, providing a drop-off recycling center for receiving a plurality of recyclable materials from at least the first entity, receiving the recyclable materials at the drop-off center for processing, measuring and recording quantitative or qualitative data for the recyclable materials, calculating a reward correlating to the quantitative or qualitative data recorded for the recyclable materials and crediting the account for the first entity with the reward. | 01-15-2009 |
| 20090024479 | COMMUNITY-BASED RECYCLING SYSTEM AND METHODS THEREOF - Embodiments of the present invention generally relate to a community-based recycling system and methods of utilizing same. In one embodiment of the present invention, a community-based recycling system comprises a first entity, providing recyclable material, a second entity, providing recyclable material, a load determining device for obtaining a qualitative or quantitative measurement of the recyclable material accumulated from both the first entity and the second entity, and a reward granted equally to each of the first entity and the second entity, wherein the reward corresponds to a value generated from the measurement of the recyclable material. | 01-22-2009 |
Guixiang Yang, Plainville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110129673 | SILVER-COATED BORON NITRIDE PARTICULATE MATERIALS AND FORMULATIONS CONTAINING SAME - In accordance with the present invention, there are provided filled epoxy-based formulations wherein the filler comprises silver-coated boron nitride particulate material. In accordance with a further embodiment of the present invention, there are provided articles comprising particulate boron nitride having a silver coating on at least a portion of the surface thereof. In additional embodiments of the present invention, there are provided methods for the use of invention articles and formulations. | 06-02-2011 |
Guohan Yang, Mansfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080305557 | Novel Applications of Acridinium Compounds and Derivatives in Homogeneous Assays - Chemiluminescent acridinium compounds are used in homogeneous assays to determine the concentration of an analyte in a sample without strong acid or strong base treatment. The chemiluminescent acridinium compounds include acridinium esters with electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus to inhibit pseudo-base formation, or acridinium sulfonamides with or without electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus. | 12-11-2008 |
| 20090029349 | Novel Applications of Acridinium Compounds and Derivatives in Homogeneous Assays - Chemiluminescent acridinium compounds are used in homogeneous assays to determine the concentration of an analyte in a sample without strong acid or strong base treatment. The chemiluminescent acridinium compounds include acridinium esters with electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus to inhibit pseudo-base formation, or acridinium sulfonamides with or without electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus. | 01-29-2009 |
| 20100048483 | POLYMERIC BENZYL CARBONATE-DERIVATIVES - The present invention relates to polymeric derivatives, which can be conjugated to an amino-containing drug to improve its in vivo properties. The polymeric derivative can subsequently be released to yield the drug in its native form. Methods of preparing and using these polymeric derivatives and drug conjugates are described. | 02-25-2010 |
| 20110046052 | Excipients for Protein Stabilization - This invention is a method of using a class of excipients for protein formulation to reduce and/or eliminate protein aggregation in solutions or solids. This class of compounds contains carbonyl group(s) to form Schiff base(s) with amino groups of proteins and also contains moieties to keep protein molecules spatially separated. This method has never been disclosed anywhere in the literature. | 02-24-2011 |
Hongbo Yang, Natick, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090007064 | Size vector sharing in code generated for variable-sized signals - A method and apparatus to generate code to represent a graphical model formed of multiple graphical modeling components and at least one variable-sized signal is presented. Each variable-sized signal is represented using a size-vector in the generated code. The generated code is optimized by representing multiple variable-sized signals with the same size-vector such that at least two variable-sized signals share a size-vector in the generated code. The size of the variable-sized signal is capable of changing during the execution of the graphical model. The method and apparatus also identifies the owners of the variable-sized signals. | 01-01-2009 |
| 20120005650 | HARDWARE SPECIFIC CODE GENERATION - A computer-implemented method for generating code based on a graphical model may include: translating the graphical model into a graphical model code, the graphical model code including a first graphical model code function; performing a lookup of the first graphical model code function in a hardware specific library, the hardware specific library comprising a plurality of relationships between graphical model code functions and hardware specific functions, where the first graphical model code function is one of the graphical model code functions; obtaining a matched hardware specific function based on the lookup, wherein the matched hardware specific function is one of the hardware specific functions from the hardware specific library; and modifying the graphical model code based on the matched hardware specific function. | 01-05-2012 |
Hongfang Yang, Burlington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100009936 | CHEMICAL COMPOUNDS - The invention provides compounds formula I, their preparation, and their use as pharmaceutically active immuno-suppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or SIP receptors. | 01-14-2010 |
| 20100016260 | AGONISTS OF SPHINGOSINE-1 PHOSPHATE RECEPTOR (SLP) - The invention provides compounds of formula I and formula II, their preparation, and their use as pharmaceutically active immunosuppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or SIP receptors. | 01-21-2010 |
Hu Yang, Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100063095 | HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER - The present invention provides compounds having formula (I): | 03-11-2010 |
| 20110071169 | Preparation of polymorphic form of lapatinib ditosylate - The present invention is directed to two novel polymorph form (Form A and Form B) of lapatinib ditosylate, wherein Form A is the hydrate ditosylate salt of lapatinib, and Form B is anhydrate ditosylate salt of lapatinib. The present invention is further directed to amorphous form of lapatinib ditosylate and its solid dispersion. The present invention further provides processes for the preparation of Form A, Form B, Amorphous form and solid dispersion of lapatinib ditosyalte, and a pharmaceutical composition comprising the said forms. Form A and Form B were characterized by X-RPD, DSC, TGA and FT-IR, and can be prepared from recrystallizing lapatinib ditosylate in a mixture of tetrahydrofuran (THF) and water. | 03-24-2011 |
Jane Yang, Boxborough, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090264653 | USEFUL INDOLE COMPOUNDS - Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO. | 10-22-2009 |
| 20100197708 | INDOLE COMPOUNDS - Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole. | 08-05-2010 |
Jean Yang, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100192130 | AUTOMATED VERIFICATION OF A TYPE-SAFE OPERATING SYSTEM - An “Automated, Static Safety Verifier” uses typed assembly language (TAL) and Hoare logic to achieve highly automated, static verification of type and memory safety of an operating system (OS). Various techniques and tools mechanically verify the safety of every assembly language instruction in the OS, run-time system, drivers, and applications, except the boot loader (which can be separately verified). The OS includes a “Nucleus” for accessing hardware and memory, a kernel that builds services running on the Nucleus, and applications that run on top of the kernel. The Nucleus, written in verified assembly language, implements allocation, garbage collection, multiple stacks, interrupt handling, and device access. The kernel, written in C# and compiled to TAL, builds higher-level services, such as preemptive threads, on top of the Nucleus. A Hoare-style verifier with automated theorem prover verifies safety and correctness of the Nucleus. A TAL checker verifies safety of the kernel and applications. | 07-29-2010 |
Jicheng Yang, North Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110198714 | PACKAGES AND METHODS FOR PACKAGING MEMS MICROPHONE DEVICES - Microelectromechanical systems (MEMS) microphone devices and methods for packaging the same include a package housing, an interior lid, and an integrated MEMS microphone die. The package housing includes a sound port therethrough for communicating sound from outside the package housing to an interior of the package housing. The interior lid is mounted to an interior surface of the package housing to define an interior lid cavity, and includes a back volume port therethrough. The MEMS microphone die is mounted on the interior lid over the back volume port, and includes a movable membrane. The back volume port is configured to allow the interior lid cavity and the MEMS movable membrane to communicate, thereby increasing the back volume of the MEMS microphone die and enhancing the sound performance of the packaged MEMS microphone device. | 08-18-2011 |
| 20120126347 | PACKAGES AND METHODS FOR PACKAGING - Packaged integrated devices and methods of forming the same are provided. In one embodiment, a packaged integrated device includes a package substrate, a package lid, and an integrated circuit or microelectromechanical systems (MEMS) device. The package lid is mounted to a first surface of the package substrate using an epoxy, and the package lid and the package substrate define a package interior. The package lid includes an interior coating suited to good adhesion with the epoxy, and an exterior coating suited to RF shielding, where the materials of the interior and exterior coatings are different. In one example, the interior lid coating is nickel whereas the exterior lid coating is tin. | 05-24-2012 |
Jingjing Yang, Boxborough, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090131395 | BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS - The invention relates to a chemical genus of 4-biphenyl-1-phenylazetidin-2-ones useful in the treatment of hypercholesterolemia and other disorders. The compounds have the general formula I: | 05-21-2009 |
| 20090292135 | ORGANOMETAL BENZENEPHOSPHONATE COUPLING AGENTS - The invention relates to chemical genera of organometal benzenephosphonates useful in cross-coupling organic synthesis, having general formula: | 11-26-2009 |
Joel K. Yang, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100078854 | Nanotemplate arbitrary-imprint lithography - In a method for imprinting a layer of material, a nanotemplate is impressed into a material layer, and the nanotemplate is maintained impressed in the material layer until a geometric trench corresponding to geometry of the nanotemplate is formed in the layer, and the nanotemplate is then removed from the material layer. A nanotemplate geometric trench is repeatedly formed in the material layer by nanotemplate impressions in the layer, until a final desired imprint pattern is produced in the layer. Each nanotemplate geometric trench is characterized by an extent that is a fraction of an extent of the final desired imprint pattern. The material layer is maintained in a condition for accepting nanotemplate impressions continuously throughout the nanotemplate impression repetition. | 04-01-2010 |
Joel K.w. Yang, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090050790 | MULTI-ELEMENT OPTICAL DETECTORS WITH SUB-WAVELENGTH GAPS - A multi-element optical detector includes a plurality of optical detector elements capable of producing an output signal having information about the state of an incident electromagnetic radiation as a function of time. An active region includes a photosensitive region of one of the optical detector elements separated in part or in whole from the photosensitive region of at least one other optical detector element by a distance less than the wavelength of the electromagnetic radiation that the optical detector elements are being used to detect. | 02-26-2009 |
Joel Kwang Wei Yang, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090092803 | SELF-ASSEMBLY TECHNIQUE APPLICABLE TO LARGE AREAS AND NANOFABRICATION - The present invention provides articles and methods for affecting the self-assembly of materials. In some cases, the invention provides an approach for facilitating the self-assembly of various materials, including polymeric materials (e.g., block polymers), nanoparticles, other materials capable of self-assembly, and the like, over relatively large surface areas. Some embodiments of the invention provide articles (e.g., substrates) which, when contacted with a material capable of self-assembly, may produce greater control of self-assembly through the bulk of the material. | 04-09-2009 |
Jungwook Yang, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080224743 | SEQUENCE INDEPENDENT NON-OVERLAPPING DIGITAL SIGNAL GENERATOR WITH PROGRAMMABLE DELAY - A circuit for generating non-overlapping clock signals includes a programmable delayed reference clock signals circuit to produce a plurality of delayed reference clock signals and a plurality of delay clock signal generators, operatively connected to the programmable delayed reference clock signals circuit, to generate non-overlapping clock signals. Each delay clock signal generator includes a latch or flip-flop to control a delay in a rising edge of a clock signal and to output a first signal, another latch or flip-flop to control a delay in a falling edge of a delayed clock signal and to output a first signal, and a logic circuit to generate the clock signal from the first and second signals. The latches or flip-flops independently control a delay in the rising edge of the clock signal in response to one of the plurality of delayed reference clock signals. | 09-18-2008 |
| 20120001779 | SERIALIZER CIRCUIT - The described embodiments may provide a chemical detection circuit. The chemical detection circuit may comprise a pixel array, a pair of analog-to-digital converter (ADC) circuit blocks, a pair of input/output (I/O) circuit blocks coupled to the pair of ADC circuit blocks respectively, and a plurality of serial link terminals coupled to the pair of IO circuit blocks. The pixel array may comprise a plurality of chemically-sensitive pixels formed in columns and rows. Each chemically-sensitive pixel may comprise: a chemically-sensitive transistor, and a row selection device. | 01-05-2012 |
| 20120074956 | METHOD AND SYSTEM FOR DELTA DOUBLE SAMPLING - An array of sensors arranged in matched pairs of transistors with an output formed on a first transistor and a sensor formed on the second transistor of the matched pair. The matched pairs are arranged such that the second transistor in the matched pair is read through the output of the first transistor in the matched pair. The first transistor in the matched pair is forced into the saturation (active) region to prevent interference from the second transistor on the output of the first transistor. A sample is taken of the output. The first transistor is then placed into the linear region allowing the sensor formed on the second transistor to be read through the output of the first transistor. A sample is taken from the output of the sensor reading of the second transistor. A difference is formed of the two samples. | 03-29-2012 |
Kejian Yang, Northborough, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080267963 | Methods of Cancer Treatment/Prevention Using Cancer Cell-Specific Surface Antigens - The invention relates to methods and reagents for immunizing and treating individual with cancer to elicit specific cellular and humoral immune-responses against specific cancer cell surface antigens, including those cancer cell surface antigens expressed only in cancer cells and in non-cancer cells normally located in one or more immune-privileged sites or tissues of the individual. The invention provides methods of using specifically prepared immunogen in fresh or lyophilized liposome, proper routes of administration of the immunogen, proper doses of the immunogen, and specific combinations of heterologous immunization including DNA priming in one administration route followed by liposome-mediated protein antigen boost in a different route to tailor the immune responses in respects of enhancing cell mediated immune response, cytokine secretion, humoral immune response, especially skewing T helper responses to be Th1 or a balanced Th1 and Th2 type. | 10-30-2008 |
| 20120027841 | NOVEL MUCOSAL VACCINATION APPROACH FOR HERPES SIMPLEX VIRUS TYPE-2 - The invention provides methods and kits for immunizing animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. The protective immune response elicited by the methods and kits of the invention is characterized by robust humoral, cellular, and mucosal immunity. In particular, the invention provides a heterologous immunization method comprising a priming DNA vaccine encoding an antigen and a boosting protein vaccine, in which the protein form of the antigen is encapsulated in liposomes. Methods of preventing primary acute, latent and recurrent viral infections, such as that caused by HSV-2 virus, and methods of providing passive protective immunity against a viral pathogen such as HSV-2 virus to a mammal are also disclosed. | 02-02-2012 |
Kuang Yang, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090294879 | Method for Capping a MEMS Wafer - A method for capping a MEMS wafer to form a hermetically sealed device. The method includes applying a glass bonding agent to the cap wafer and burning off organic material in the glass bonding agent. The cap wafer/glass bonding agent combination is then cleaned to reduce lead in the combination. The cleaning is preferably accomplished using an oxygen plasma. The MEMS device is coated with a WASA agent. The cap wafer is then bonded to the MEMS wafer by heating this combination in a capping gas atmosphere of hydrogen molecules in a gas such as nitrogen, argon or neon. This method of capping the MEMS wafer can reduce stiction in the MEMS device. | 12-03-2009 |
| 20100242604 | MEMS Device with Opposite Polarity Spring Bimorph - A MEMS device has a mass supported at least in part by a spring. Among other things, the spring has first and second layers, and first and a second electrodes. The first and second layers are between the first and second electrodes, and the first and second layers, which are oppositely polarized, form a bimorph. | 09-30-2010 |
| 20110073967 | APPARATUS AND METHOD OF FORMING A MEMS ACOUSTIC TRANSDUCER WITH LAYER TRANSFER PROCESSES - A method of forming a MEMS microphone forms circuitry and first MEMS microstructure on a first wafer in a first process, and second MEMS microstructure on a second wafer in a second process. The first process is thermally isolated from the second process. The method also layer transfers the second MEMS microstructure onto the first wafer. The first MEMS microstructure and second MEMS microstructure thus form a variable capacitor that communicates with the circuitry on the first wafer. | 03-31-2011 |
Kuang L. Yang, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090320557 | MEMS Stiction Testing Apparatus and Method - A MEMS stiction testing method applies a first electrical signal to a MEMS device having two opposing surfaces to cause the two opposing surfaces to make physical contact. The two opposing surfaces produce a second electrical signal when in physical contact. The method then substantially mitigates the first electrical signal after detecting that the second electrical signal has reached a prescribed maximum value. | 12-31-2009 |
| 20100283138 | Nickel-Based Bonding of Semiconductor Wafers - A nickel-based material is used on one or both wafers to be bonded, and the two wafers are bonded at low temperature and pressure through interdiffusion of the nickel-based material with either another nickel-based material or aluminum. In various embodiments, nickel-based walls are formed on one wafer, and corresponding walls are formed on the other wafer from a nickel-based material or aluminum. The walls of the two wafers are placed in contact with one another under sufficient pressure and temperature to cause bonding of the walls through interdiffusion. | 11-11-2010 |
| 20110073859 | Reduced Stiction MEMS Device with Exposed Silicon Carbide - A MEMS device has a first member that is movable relative to a second member. At least one of the first member and the second member has exposed silicon carbide with a water contact angle of greater than about 70 degrees. | 03-31-2011 |
| 20110075865 | Dual Single-Crystal Backplate Microphone System and Method Of Fabricating Same - A dual backplate MEMS microphone system includes a flexible diaphragm sandwiched between two single-crystal silicon backplates. Such a MEMS microphone system may be formed by fabricating each backplate in a separate wafer, and then transferring one backplate from its wafer to the other wafer, to form two separate capacitors with the diaphragm. | 03-31-2011 |
| 20120111113 | BAW Gyroscope with Bottom Electrode - A bulk acoustic wave gyroscope has a primary member in a member plane, and an electrode layer in an electrode plane spaced from the member plane. The electrode layer has a first portion that is electrically isolated from a second portion. The first portion, however, is mechanically coupled with the second portion and faces the primary member (e.g., to actuate or sense movement of the primary member). For support, the second portion of the electrode is directly coupled with structure in the member plane. | 05-10-2012 |
Liping Yang, Arlington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110123435 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY - The present invention relates to compounds of Formula (I), below, (wherein X, R1, R2, R3, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity. Formula I | 05-26-2011 |
| 20110150757 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY - The present invention relates to compounds of Formula (I), below, (wherein R1, R2, R3, R27, R28, R29, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity. | 06-23-2011 |
| 20110171172 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY - The present invention relates to compounds of Formula (I), below, (wherein R | 07-14-2011 |
| 20120010181 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF—or combinations thereof. | 01-12-2012 |
| 20120015926 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. | 01-19-2012 |
Liwen Yang, Burlington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100121934 | MANAGED PEER-TO-PEER FILE SHARING - A system and method for managed peer-to-peer (p2p) file sharing. The peer nodes can include a web browser and a p2p agent. The web browser can connect to the Internet and can interface with the p2p agent. The p2p agent provides the file sharing utilities for implementing the p2p network. A web server connected to the Internet can monitor and manage p2p activity, including providing persistent storage for the p2p networks. The web server can interface with a Public Switched Telephone Network (PSTN) to provide access to the p2p network for PSTN peer nodes that do not have web browsing capabilities. A method of implementing managed p2p file sharing includes registering users; providing login and logout functions; creating p2p sessions; preparing, forwarding, receiving, accepting and/or rejecting invitations to join p2p sessions; quitting p2p sessions; deleting p2p sessions or selected members of p2p sessions; and sharing and transferring files. | 05-13-2010 |
Luhan Yang, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110104787 | Fusion Peptides That Bind to and Modify Target Nucleic Acid Sequences - Novel methods and compositions for altering target nucleic acid (e.g., DNA e.g., genomic DNA) sequences are provided. Fusion proteins including one or more DNA binding domains and one or more DNA modifying domains are provided. Isolated polynucleotides encoding fusion proteins including one or more DNA binding domains and one or more DNA modifying domains are provided. | 05-05-2011 |
Mark X. Yang, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080311101 | Method to Reduce Oxalate Concentration by Administration of Oxalate Oxidase Crystals - The invention relates to methods to prevent, treat, or slow the progression of a disorder associated with elevated oxalate concentration, the method comprising administering oxalate oxidase crystals, cross-linked crystals, or compositions containing those crystals to an individual. Oxalate oxidase crystals and compositions for administration to an individual are also provided, including stabilized crystals, such as cross-linked crystals of oxalate oxidase. | 12-18-2008 |
| 20090093617 | Crystals of whole antibodies and fragments thereof and methods for making and using them - This invention relates to crystals of whole antibodies and fragments thereof, and formulations and compositions comprising such crystals. More particularly, methods are provided for the crystallization of high concentrations of whole antibodies, and fragments thereof, in large batches, and for the preparation of stabilized whole antibody crystals for use alone, or in dry or slurry formulations or compositions. This invention also relates to methods for stabilization, storage and delivery of biologically active whole antibody crystals. The present invention further relates to methods using whole antibody crystals, antibody fragment crystals, or compositions or formulations comprising such crystals for biomedical applications, including biological delivery to humans and animals. More particularly, whole antibody crystals or antibody fragment crystals, or crystal compositions or formulations thereof, are used as a carrier-free delivery system which can slowly release active whole antibodies or fragments thereof, to a subject, where and when they are needed. | 04-09-2009 |
| 20100047248 | METHODS OF PROCESSING COMPOSITIONS CONTAINING MICROPARTICLES - A method for processing multi-phasic dispersions is provided. The method comprises providing a multi-phasic dispersion including dispersed and continuous phases, providing one or more non-solvents comprising an aqueous solution containing at least one multivalent cation, exposing the multi-phasic dispersion to the non-solvent to form a suspension containing one or more liquid phases and the solid microparticles, and removing at least a portion of the resulting one or more liquid phases while retaining at least the microparticles, thereby removing at least a portion of the non-volatile material from the microparticles. | 02-25-2010 |
Meijia Yang, Scituate, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090130712 | Compositions and Methods of Producing Hybrid Antigen Binding Molecules and Uses Thereof - This disclosure relates to hybrid antigen binding molecules including at least two polypeptide chains, with at least one polypeptide chain comprises an antigen binding moiety linked to an amino acid sequence of a subunit of a heterodimeric proteinaceous hormone. Also disclosed are methods of making and using such hybrid antigen binding molecules for diagnosis and/or therapy. | 05-21-2009 |
| 20100184090 | Method for Generating Stable Cell Lines Expressing High Levels of a Protein of Interest - This invention relates to industrial production of proteins. More specifically, the invention relates to a method for obtaining cells that stably express a protein of interest, even when cultivated in the absence of selective pressure. DHFR is used as a surrogate marker. The transfected cells are not selected based on resistance to a toxic compound, but based on fluorescence as measured by FACS using fluorescent MTX. | 07-22-2010 |
Ming-Ta Yang, Carlisle, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090099796 | AEROELASTIC MODEL USING THE PRINCIPAL SHAPES OF MODES (AMPS) - The Aeroelastic Model using the Principal Shapes of modes (AMPS) is a method used to predict flutter in gas turbine engines. Modern gas turbine engines often include rotors with flexible disks and/or significant blade geometry variations. The AMPS method accounts for the varying blade mode shapes associated with flexible disks as well as changing blade geometry, providing accurate flutter predictions for a large number of modes from a relatively small number of CFD (computational fluid dynamics) simulations. The AMPS method includes determining a smaller set of principal shapes that approximates a larger set of structural modes of interest. Using linear superposition, aerodynamic forces associated with the vibration of the principal shapes can be used to construct the full aerodynamic coupling matrix associated with the structural modes of interest. An eigenvalue equation is solved to determine a damping distribution associated with the structural modes of interest. The damping distribution is predictive of flutter. | 04-16-2009 |
Qin Yang, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100009363 | RBP4 In Insulin sensitivity/resistance, diabetes, and obesity - Methods for screening molecules that modulate the activity of Retinol Binding Protein 4 (RBP4) and their use in treatment of insulin resistance are described. Also described are methods of diagnosing insulin resistance and related conditions by detecting modulation of RBP4 activity. | 01-14-2010 |
Robert Yang, Medford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110312919 | INHIBITORS OF TYROSINE KINASE RECEPTOR DIMERIZATION - The teachings relate to methods of identifying inhibitors of dimerization of tyrosine receptor kinases such as EGFR. The methods comprise providing, on a digital computer, a molecular model comprising a complex of extracellular dimerization domains of an RTK, docking a chemical databases to the molecular model, scoring the compounds comprised by the database, and identifying one or more high-scoring compounds. The methods further comprise testing a compound for RTK inhibitory activity in vitro, and testing a compound for specificity as an RTK inhibitor. Also disclosed are compounds selected by the described methods, and methods of treatment using the compounds. Two compounds (NSC11241 and NSC56452) are disclosed that inhibit EGF receptor kinase activation in a dose-dependent manner. | 12-22-2011 |
Rong Yang, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110237495 | FUNCTIONAL METABOLOMICS COUPLED MICROFLUIDIC CHEMOTAXIS DEVICE AND IDENTIFICATION OF NOVEL CELL MEDIATORS - The invention relates to the use of microfluidic chemotaxis device to identify novel active compounds of the metabolome and methods to characterize their actions on cell motility. The invention also includes the active compounds of the metabolome identified by the methods and devices disclosed herein. The results from these in vitro experiments were then correlated with in vivo physiologic responses to identify the downstream effects and therapeutic value. Thus, the invention provides novel methods for treating or preventing second organ injury resulting from ischemia-reperfusion in a patient in need thereof The invention also provides methods of treating, preventing or ameliorating connective tissue degeneration in a patient in need thereof. The invention also provides methods of treating or preventing bone loss. In addition, the invention provides method for inducing bone regeneration in patients in need thereof or preventing bone loss in patients suspected to be in need thereof. | 09-29-2011 |
| 20110288317 | 14-HYDROXY-DOCOSAHEXAENOIC ACID COMPOUNDS - The invention describes novel 14-hydroxy docosahexaenoic acid (DHA) analogues, their preparation, isolation, identification, purification and uses thereof. | 11-24-2011 |
Rui-Yang Yang, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090130117 | Substituted Tetrazole Compounds and Uses Thereof - The present invention provides tetrazole compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising the tetrazole compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound of the present invention. | 05-21-2009 |
| 20100172867 | SUBSTITUTED 1H-PYRAZOLO[3,4-D]PYRIMIDINE-6-AMINE COMPOUNDS - The present invention relates to substituted 1H-pyrazolo-[3,4-d]pyrimidine-6-amine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted 1H-pyrazolo-[3,4-d]pyrimidine-6-amine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 07-08-2010 |
| 20100239525 | SUBSTITUTED 5,6-DIHYDRO-6-PHENYLBENZO[F]ISOQUINOLIN-2-AMINE COMPOUNDS - The present invention relates to substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 09-23-2010 |
| 20100249109 | SUBSTITUTED TETRAHYDROPYRAZOLO-PYRIDO-AZEPINE COMPOUNDS - The present invention relates to substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 09-30-2010 |
| 20110166127 | Substituted Benzo-Pyrimido-Tetrazolo-Diazepine Compounds - The present invention relates to substituted benzo-pyrimido-tetrazolo-diazepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted benzo-pyrimido-tetrazolo-diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 07-07-2011 |
| 20110245236 | Substituted Benzo-Pyrido-Triazolo-Diazepine Compounds - The present invention relates to substituted benzo-pyrido-triazolo-diazepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted benzo-pyrido-triazolo-diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds or pharmaceutical compositions to subjects in need thereof. | 10-06-2011 |
| 20120015935 | Substituted Tetrahydropyrazolo-Pyrido-Azepine Compounds - The present invention relates to substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 01-19-2012 |
Sheng-Hui Yang, Acton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100239257 | LOGICAL PARTITIONING OF A PASSIVE OPTICAL NETWORK - In order to increase the capacity of a deployed passive optical network (PON) without replacing optical network terminators (ONTs), a PON is provided that is partitioned into multiple channels. The upstream and downstream channels in the PON are partitioned into M channels, with the number of channels on the upstream preferably equaling the number of channels on the downstream. In the downstream, the partitioning is accomplished by use of wavelength division multiplexing filters arranged in a way as to place groups of ONTs on M different wavelength bands, where all of the wavelength bands are within the downstream wavelength range of the existing PON. On the upstream, partitioning is accomplished using “injection locking” to narrow the possible wavelength range of each ONT transmitter to a portion of that possible in the existing PON. | 09-23-2010 |
Suizhou Yang, Lowell, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080293856 | Stabilized polyolefin compositions - Disclosed are compositions comprising antioxidants and stabilizers, such as, acid scavengers or organic phosphorus stabilizers, and optionally further comprising co-stabilizers. The disclosed compositions are useful as stabilizers for polyolefins and other polymeric materials. The disclosed compositions and methods generally provide longer shelf lives and better oxidative resistance to materials than currently available antioxidants. | 11-27-2008 |
| 20100084607 | Macromolecular antioxidants and polymeric macromolecular antioxidants - Disclosed are macromolecular antioxidants represented by a structural formula selected from I-VI: | 04-08-2010 |
| 20110040125 | NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS - Disclosed are compounds represented by structural formula (I): | 02-17-2011 |
| 20120004150 | Lubricant Oil Compositions - Compositions comprise first antioxidants and first additives, such as, a surface additives, performance enhancing additives and lubricant protective additives and optionally second additives and/or second antioxidants. The compositions are useful to improve lubricants, lubricant oils and other lubricant materials. The compositions and methods generally provide longer shelf lives, increased oxidative resistance, improved quality and/or enhanced performance to lubricants or lubricant oils. | 01-05-2012 |
Sui-Zhou Yang, Dracut, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100305251 | STABILIZED POLYOLEFIN COMPOSITIONS - Disclosed are compositions comprising antioxidants and stabilizers, such as, acid scavengers or organic phosphorus stabilizers, and optionally further comprising co-stabilizers. The disclosed compositions are useful as stabilizers for polyolefins and other polymeric materials. The disclosed compositions and methods generally provide longer shelf lifes and better oxidative resistance to materials than currently available antioxidants. | 12-02-2010 |
| 20120071596 | STABILIZED POLYOLEFIN COMPOSITIONS - Disclosed are compositions comprising antioxidants and stabilizers, such as, acid scavengers or organic phosphorus stabilizers, and optionally further comprising co-stabilizers. The disclosed compositions are useful as stabilizers for polyolefins and other polymeric materials. The disclosed compositions and methods generally provide longer shelf lifes and better oxidative resistance to materials than currently available antioxidants. | 03-22-2012 |
Tom C.s. Yang, Wayland, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080230046 | Self-heating, self-hydrating pouch to simultaneously hydrate and heat completely or partially dehydrated food or beverage products in said pouch - A self-heating, self-hydrating pouch to simultaneously heat and hydrate a prepackaged, partially or completely dehydrated food or beverage product that is stored in the pouch. The pouch comprises multiple layers of material that prevent the transmission of water and gasses thereby preventing deterioration of the prepackaged food or beverage product. The pouch includes a membrane filter structure and flameless, exothermic reaction agents. The user adds potable or non-potable water to the pouch. When the water contacts the exothermic reaction agents, an exothermic reaction occurs which heats the water above 200° F. The membrane filter structure filters the heated water to remove bacteria, viruses, chemicals and by-products of the exothermic reaction. The filtered, heated water contacts the partially or completely dehydrated food product or dehydrated beverage product and simultaneously heats and hydrates the food or beverage product. | 09-25-2008 |
Weide Victor Yang, Longmeadow, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120100316 | HALO-FREE HEAT TRANSFER LABEL WITH PIGMENTED ADHESIVE - A pigmented adhesive, halo-free heat transfer label is created when adhesive properties are incorporated into colored inks used to print graphics on labels for items such as apparel. The resulting label has a halo-free graphic applied thereto that eliminates the need for a separate application of adhesive to the label. A pigmented adhesive composition for use with heat transfer type labels includes a hydroxyl-functional polyurethane dispersion, one or more polyurethane dispersions different from the hydroxyl-functional polyurethane dispersion, a blocked cross-linking agent, a catalyst for the blocked cross-linking agent, a pigment dispersion, and an adhesive powder, which are combined prior to the formation of a graphic created using the combined mixture, on the release layer of a substrate. | 04-26-2012 |
Weiping Yang, Dartmouth, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090155348 | Detoxified Recombinant Botulinum Neurotoxin - The present invention relates to the isolation of polypeptides derived from the | 06-18-2009 |
Wen Yang, Sharon, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120134970 | Viral Vectors Encoding Multiple Highly Homologus Non-Viral Polypeptides And The Use Of Same - The present invention relates to compositions and methods for creation of vector nucleic acid sequences (e.g., retroviral nucleic acid sequences) that comprise two or more exogenous nucleic acid sequences that encode highly homologous (e.g., identical) polypeptide sequences, yet wherein at least one of the exogenous nucleic acid sequences has been mutated using degenerate codons for purpose of reducing homology between the two or more exogenous nucleic acid sequences while maintaining the encoded polypeptide sequence. Preferred nucleic acid sequences include those encoding multi-chimeric immune receptor (CIR) genes. Specific nucleic acid sequences of such CIR genes are also disclosed. | 05-31-2012 |
Wenhua Yang, Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090189672 | Pseudo-differential active RC integrator - A pseudo-differential active RC integrator is described. The pseudo-differential active RC integrator includes a common-mode feedback sub-circuit to control the common-mode output signal of the integrator. The common-mode feedback subcircuit may be coupled to one or more virtual ground nodes of the pseudo-differential active RC integrator, and may include one or more transconductors. | 07-30-2009 |
Wenhua Yang, North Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090251347 | Methods and apparatus for rotating a thermometer code - In one aspect, an apparatus for data conversion is provided. The apparatus comprises a plurality of inputs whose values together define a thermometer code to be converted to an analog output signal on each of a plurality of successive time increments, a plurality of conversion elements, each configured to convert one of the values at the plurality of inputs into an output signal, a shift circuit having a plurality of outputs connected to the plurality of conversion elements, the shift circuit coupled between the plurality of inputs and the plurality of conversion elements, the shift circuit selectively providing the values at the plurality of inputs to the plurality of conversion elements on the plurality of outputs to apply a rotation on each of the plurality of successive time increments, the rotation being indicated by a rotation pointer, and a pointer circuit coupled to the shift circuit and adapted to generate the rotation pointer on each of the successive time increments based on the values at the plurality of outputs during a preceding time increment, the pointer circuit indicating to the shift circuit which of the values at the plurality of inputs are to be provided to which of the plurality of conversion elements on a current time increment. | 10-08-2009 |
Xiaobin Yang, Woburn, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110255789 | SYSTEMS AND METHODS FOR AUTOMATICALLY EXTRACTING DATA FROM ELECTRONIC DOCUMENTS CONTAINING MULTIPLE LAYOUT FEATURES - A method of automatically extracting data from an electronic document containing a plurality of layout features through progressive refinement is provided. The method includes: analyzing each document to automatically extract images and text features wherein each document includes at least two features that are related to each other, and wherein said analyzing compares extracted features with a first search space of candidate features to try and recognize the extracted features; if one of the at least two related features is not recognized and at least one feature is recognized, selecting a second search space of candidate features in response thereto and in response to predefined rules about the relationship between the two features; and comparing the unrecognized feature with said selected second search space. | 10-20-2011 |
| 20110258150 | SYSTEMS AND METHODS FOR TRAINING DOCUMENT ANALYSIS SYSTEM FOR AUTOMATICALLY EXTRACTING DATA FROM DOCUMENTS - A method of training a document analysis system to extract data from documents is provided. The method includes: automatically analyzing images and text features extracted from a document to associate the document with a corresponding document category; comparing the extracted text features with a set of text features associated with corresponding category of the document, in which the set of text features includes a set of characters, words, and phrases; if the extracted features are found to consist of the characters, words, and phrases belonging to the set of text features associated with the corresponding document category, storing the extracted text features as the data contained in the corresponding document; and, if the extracted text features are found to include at least one text feature that does not belong to the set of text features associated with the corresponding document category, submitting the unrecognized text features to a training phase. | 10-20-2011 |
Xiaoke Yang, Boxborough, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080201863 | Knife attachment preventing food sticking to knife surface - A device when attached to a regular kitchen knife that serves as a wedge between the food slice and the knife surface and therefore separating the food slice from the knife surface during a cutting process comprising a stainless steel shell with a curved edge and a convex surface, magnets and rubber stripes fixed together so that this device can be used as an attachment to a knife surface by attraction between the magnets and the ferromagnetic steel knife blade. The rubber stripes provide additional friction between the attachment and the knife surface and prevent sliding of the attachment during cutting. The bubble-like convex surface of the steel shell further prevents food sticking on the surface of the device. The device can be easily attached to and removed from a knife blade. | 08-28-2008 |
| 20090156421 | ASSAYS AND METHODS FOR EVALUATING MULTIMERIC COMPLEXES - Assays, e.g., homogenous assays, and methods for identifying, quantifying and/or monitoring the formation and/or stability of a multimeric complex, e.g., a ternary complex are disclosed. The methods and assays of the invention can be used to identify and/or evaluate agents (e.g., proteins, peptides, antibody molecules, and small and large molecules) that interfere with and/or inhibit the formation of a multimeric complex (e.g., a ternary complex) or that disrupt a previously formed complex. | 06-18-2009 |
Ye Yang, Worcester, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100123897 | SYSTEMS AND METHODS FOR CORRECTING OPTICAL REFLECTANCE MEASUREMENTS - We disclose measurement systems and methods for measuring analytes in target regions of samples that also include features overlying the target regions. The systems include: (a) a light source; (b) a detection system; (c) a set of at least first, second, and third light ports which transmit light from the light source to a sample and receive and direct light reflected from the sample to the detection system, generating a first set of data including information corresponding to both an internal target within the sample and features overlying the internal target, and a second set of data including information corresponding to features overlying the internal target; and (d) a processor configured to remove information characteristic of the overlying features from the first set of data using the first and second sets of data to produce corrected information representing the internal target. | 05-20-2010 |
| 20110264411 | SYSTEMS AND METHODS FOR CORRECTING OPTICAL REFLECTANCE MEASUREMENTS - We disclose measurement systems and methods for measuring analytes in target regions of samples that also include features overlying the target regions. The systems include: (a) a light source; (b) a detection system; (c) a set of at least first, second, and third light ports which transmit light from the light source to a sample and receive and direct light reflected from the sample to the detection system, generating a first set of data including information corresponding to both an internal target within the sample and features overlying the internal target, and a second set of data including information corresponding to features overlying the internal target; and (d) a processor configured to remove information characteristic of the overlying features from the first set of data using the first and second sets of data to produce corrected information representing the internal target. | 10-27-2011 |
Yingfei Yang, Belmont, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100273765 | Rifamycin analogs and uses thereof - The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3′-hydroxy analogs, 4′- and/or 6′ halo and/or alkoxy analogs, and various 5′ substituents that incorporate a cyclic amine moiety. | 10-28-2010 |
Yin Miranda Yang, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120010178 | METHODS AND COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISORDERS - Methods, compounds and compositions for promoting motor neuron survival and the treatment of a neurodegenerative disorders such as Spinal Muscular Atrophy (SMA) are described herein. | 01-12-2012 |
Yongwu Yang, Belmont, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080246962 | Linear Fiber Array Mount To a Spectrometer - A coupler for coupling a linear fiber array to a spectrometer is provided, the coupler having a tube, a linear fiber bundle array inserted through the tube, an alignment mechanism for aligning the linear fiber bundle array with a slit on the spectrometer, and a locking mechanism for locking the linear fiber bundle array to the tube. Further, a method for coupling a linear fiber array to a spectrometer is provided, the method having the steps of inserting a linear fiber bundle array through a tube, aligning the linear fiber bundle array with a slit on the spectrometer, and locking the linear fiber bundle array to the tube once it is aligned with the slit on the spectrometer. | 10-09-2008 |
Youngguang Yang, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110118446 | METHODS AND COMPOSITIONS FOR ANTIBODY PRODUCTION - Methods and compositions for antibody production are described herein to produce human antibodies in immunodeficient mice. Particularly mice are implanted with human fetal thymus cells or human thymus and human liver tissue and human hematopoietic cells followed by immunization with an antigen. Immunization involves exposure to any of a variety of antigens including tumor antigens, microbial antigens, viral antigens and/or cytokines and growth factor. | 05-19-2011 |
Zhiyong Yang, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090209601 | USE OF RXR AGONISTS FOR THE TREATMENT OF OSTEOARTHRITIS - Disclosed herein are methods of preventing and treating osteoarthritis through the use of RXR agonists. | 08-20-2009 |
Zhiyong Yang, Newtown, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090012053 | Use of LXR agonists for the treatment of osteoarthritis - Disclosed herein are methods of preventing and treating osteoarthritis through the use of LXR agonists. | 01-08-2009 |
Zibing Yang, Natick, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090243638 | Receiver for recovering and retiming electromagnetically coupled data - In one embodiment, the present invention includes a system having an electromagnetic coupler probe to electromagnetically sample signals from a device under test or a link under test and a receiver, e.g., configured as an integrated circuit that is to receive the sampled electromagnetic signals from the probe and output digital signals corresponding thereto. Other embodiments are described and claimed. | 10-01-2009 |