Yali
Yali Chen, Nantong CN
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20110094268 | METHOD FOR PRODUCING HIGH STRENGTH AND LONG COILING LENGTH SINGLE-MODE FIBER FOR SUBMARINE CABLE - A method for producing a single-mode fiber for submarine cables including washing and flame polishing of a preform, fiber drawing, coating with a first coating layer and curing therein using an UV-curing device, coating with a second coating layer and curing therein using the UV-curing device, fiber selection with a 2% screening strain, and testing the properties of the fiber. The fiber has a high strength and long coiling length exceeding 100 km and the method is easy to practice with low production cost and parameters involved therein are highly controllable. | 04-28-2011 |
Yali Guo, Beijing CN
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20130260768 | Method, Apparatus, and System for Access Control Handover of User between Base Stations - Embodiments of the present invention provide a method for access control handover of a user between base stations, which includes: acquiring, by one of a first base station and a second base station, a closed subscriber group identifier CSG ID supported by the other base station and CSG membership information of a user equipment UE in the first base station; and if the CSG ID acquired by the one base station is the same as a CSG ID supported by the local base station, performing, by the one base station, access control on the UE according to the acquired CSG membership information of the UE in the first base station and an access mode of the other base station. | 10-03-2013 |
Yali He, Germantown, TN US
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20090062341 | Nuclear receptor binding agents - The present invention relates to a novel class of selective estrogen receptor modulators (SERMs). The SERM compounds are applicable for use in the prevention and/or treatment of a variety of diseases and conditions including prevention and treatment of cancers such as prostate and breast cancer, osteoporosis, hormone-related diseases, hot flashes or vasomotor symptoms, neurological disorders, cardiovascular disease and obesity. | 03-05-2009 |
20090264534 | SELECTIVE ANDROGEN RECEPTOR MODULATORS - The present invention relates to androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity, which are nonsteroidal ligands for the androgen receptor. The selective androgen receptor modulators (SARM) are useful for a) male contraception; b) treatment of a variety of hormone-related conditions, for example conditions associated with Androgen Decline in Aging Male (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia, osteopenia, osteoporosis, benign prostate hyperplasia, alterations in mood and cognition and prostate cancer; c) treatment of conditions associated with Androgen Decline in Female (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and/or prevention of chronic muscular wasting; e) decreasing the incidence of, halting or causing a regression of prostate cancer; f) oral androgen replacement and/or other clinical therapeutic and/or diagnostic areas. | 10-22-2009 |
20100137430 | TREATING ANDROGEN DECLINE IN AGING MALE (ADAM)-ASSOCIATED CONDITIONS WITH SARMS - This invention provides methods for treatment and inhibition of a male subject having an Androgen Decline in Aging Male (ADAM)-associated condition, for example sexual dysfunction, decreased sexual libido, erectile dysfunction, hypogonadism, sarcopenia, osteopenia, osteoporosis, an alteration in cognition and mood, depression, anemia, hair loss, obesity, muscle loss, dry eye, memory loss, benign prostate hyperplasia and/or prostate cancer, by administering to the subject a selective androgen receptor modulator (SARM) compound and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, pro-drug, polymorph, crystal, or any combination thereof. | 06-03-2010 |
20120157539 | NUCLEAR RECEPTOR BINDING AGENTS - The present invention relates to a novel class of selective estrogen receptor modulators (SERMs). The SERM compounds are applicable for use in the prevention and/or treatment of a variety of diseases and conditions including prevention and treatment of cancers such as prostate and breast cancer, osteoporosis, hormone-related diseases, hot flashes or vasomotor symptoms, neurological disorders, cardiovascular disease and obesity. | 06-21-2012 |
20140005263 | TREATING ANDROGEN DECLINE IN AGING MALE (ADAM)-ASSOCIATED CONDITIONS WITH SARMS | 01-02-2014 |
Yali Li, Malden, MA US
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20150125462 | METHODS OF TREATING ANKYLOSING SPONDYLITIS USING IL-17 ANTAGONISTS - The disclosure is directed to novel personalized therapies and methods for treating ankylosing spondylitis (AS). Specifically, this disclosure relates to methods of treating a patient having AS by selectively administering an IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab, to the AS patient on the basis of that patient being predisposed to have a favorable response to treatment with the IL-17 antagonist. Also disclosed herein are diagnostic methods and transmittable forms of information useful in predicting the likelihood that a patient having AS will respond to treatment with an IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab. | 05-07-2015 |
Yali Li, Shanghai CN
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20100075952 | PYRROLO-NITROGENOUS HETEROCYCLIC DERIVATIES,THE PREPARATION AND THE PHARMCETICAL USE THEEOF - The invention provides new pyrrolo-nitrogenous heterocyclic derivatives represented by formula (I) or their salts, the preparation thereof, pharmaceutical compositions containing such derivatives and the use of such derivatives as therapeutic agents, especially as protein kinase inhibitors, wherein each substituent in formula (I) is same as defined in the description. | 03-25-2010 |
20130072488 | ARALKYL DIAMINE DERIVATIVES AND USES THEREOF AS ANTIDEPRESSANTS - Aralkyl diamine derivative of the following formula, pharmaceutically acceptable salts or uses thereof as antidepressants. The derivatives have triplex inhibiting activities of the reuptake of 5-HT, dopamine and noradrenalin, which can be administered to the patients in need of such treatment in the form of compositions orally or injectedly et al. | 03-21-2013 |
20130303518 | Methods of Inhibiting the Catalytic Activity of a Protein Kinase and of Treating a Protein Kinase Related Disorder - The invention provides a method of inhibiting the catalytic activity of a protein kinase comprising contacting said protein kinase with a compound of formula (I), or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing the same, and also provides a method of treating a protein kinase related disorder comprising a step of administering to a patient in need thereof a therapeutically effective amount of the compound of formula (I) or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing the same, wherein each substituent in formula (I) is same as defined in the description. | 11-14-2013 |
20150105399 | 3-CYANOANILINOALKYLARYLPIPERAZINE DERIVATIVE AND USE THEREOF IN PREPARING DRUGS - Disclosed in the present invention is a 3-cyanoanilinoalkylarylpiperazine derivatives and use thereof in preparing drugs; the 3-cyanoanilinoalkylarylpiperazine derivatives disclosed by the present invention has very useful pharmaceutical properties and good tolerance, especially the use as novel analgesic drugs, novel antidepressants, and novel analgesic and antidepressive drugs. This class of compounds are central analgesics regulating 5-hydroxytrptamine, and also are novel antidepressants regulating 5-hydroxytrptamine. This class of compounds also has less toxic and side effects and a higher safety range. The 3-cyanoanilinoalkylarylpiperazine derivative is a compound shown as formula (III) or free base or salt thereof: | 04-16-2015 |
Yali Liu, Davis, CA US
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20080271068 | System and method for delivering personalized advertising data - A method is disclosed for distributing advertising data in an internet protocol television (IPTV) system, the method including dividing a plurality of end user devices in the IPTV system into K advertising groups; multicasting J advertising data multicast groups to end user devices in J advertising groups having a percentile ranking above or equal to a predetermined percentile ranking; and unicasting advertising data channels for actively viewed IPTV channels being viewed by other end users. | 10-30-2008 |
20100232498 | METHOD AND APPARATUS FOR RATE CONTROL ACCURACY IN VIDEO ENCODING AND DECODING - Methods and apparatus are provided for rate control accuracy in video encoding and decoding. An apparatus includes a video encoder for encoding image data using rate control. The rate control involves estimating a quantization step size and adjusting a rounding offset. The rounding offset is capable of being non-constant during the encoding. | 09-16-2010 |
Yali Wang, Beijing CN
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20130058581 | Microscopic Vision Measurement Method Based On Adaptive Positioning Of Camera Coordinate Frame - The present disclosure provides a microscopic vision measurement method based on the adaptive positioning of the camera coordinate frame which includes: calibrating parameters of a microscopic stereo vision measurement model ( | 03-07-2013 |
20130090508 | Method for Preparing 1-Octene by Oligomerization of Ethylene - Disclosed is a method for preparing 1-octene in the presence of a catalyst system for ethylene oligomerization, which includes: premixing a part of ethylene gas as raw material with a solvent, mixing with the components a+b, c and d of the catalyst system, and then sending in a reactor; directly sending the rest of ethylene gas in the reactor; discharging the resultant liquid from the upper part of the reactor into an overflow channel; adding a catalysis stopping agent to the overflow channel; and then separating the resultant liquid. The advantages of the method are high selectivity of 1-octene and high catalytic activity. | 04-11-2013 |
20140114030 | PREPARATION METHOD OF HIGH-PERFORMANCE STAR-SHAPED POLYCARBOXYLATE SUPERPLASTICIZER - This invention relates to a method for preparing a star-shaped polycarboxylate superplasticizer by the first esterification step with polyol and (meth)acrylic acid as main reactants and the second polymerization step. In the first step, the star-shaped polymerizable active ends were synthesized by esterification between polyol and (meth)acrylic acid in the presence of catalyst. In the second step, the final star-shaped polycarboxylate superplasticizer was prepared by radical polymerization among the product obtained in first step, unsaturated polyoxyethylene ethers, molecular weight regulator and unsaturated carboxylic acid in the presence of initiator. The production process of this invention exhibits some characteristics including simple, easily controllable, high polymerization degree, low cost and pollution free. The star-shaped molecular structure of polycarboxylate superplasticizer can be achieved through synthesizing active “core” by esterification and “arm” by radical polymerization. It showed better cement paste fluidity and fluidity retention, which manifested as better adaptability to cement and application performance in concrete, than both traditional linear and comb-shaped polycarboxylate superplasticizer at common or lower dosage. | 04-24-2014 |
Yali Wang, Shanghai CN
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20140329745 | HUMAN INSULIN ANALOGUE AND ACYLATED DERIVATIVE THEREOF - The present invention provides a human insulin analogue, an acylated derivative thereof and a physiologically acceptable salt. The present invention further provides a preparation method for the insulin analogue and an application of the insulin analogue as a therapeutic agent, and particularly as a diabetes mellitus therapeutic agent. | 11-06-2014 |
Yali Wang, Lian Yungang CN
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20120129768 | GLP-1 ANALOGUES AND THEIR PHARMACEUTICAL SALTS AND USES - This invention discloses GLP-1 analogues and their pharmaceutical salts, wherein the GLP-1 analogue comprises an amino acid sequence of general formula (I), wherein Lys represents a modified lysine with a lipophilic acid. The GLP-1 analogues provided by this invention have the function of human GLP-1, and a longer half-life in vivo compared with the human GLP-1. Uses of such compounds and compositions include treating non-insulin-dependent diabetes, insulin-dependent diabetes, and obesity. | 05-24-2012 |
Yali Wang, Lianyungang CN
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20120196798 | GLP-1 ANALOGUES AND THEIR PHARMACEUTICAL SALTS AND USES - This invention discloses GLP-1 analogues and their pharmaceutical salts, wherein the GLP-1 analogue comprises an amino acid sequence of general formula (I), wherein Lys represents a modified lysine with a lipophilic acid. The GLP-1 analogues provided by this invention have the function of human GLP-1, and a longer half-life in vivo compared with the human GLP-1. Uses of such compounds and compositions include treating non-insulin-dependent diabetes, insulin-dependent diabetes, and obesity. | 08-02-2012 |
Yali Wang, Shenzhen CN
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20100210231 | COMPENSATION METHOD OF RADIO FREQUENCY MODULE PERFORMANCE AND RADIO FREQUENCY MODULE - A compensation method for radio frequency module performance, said radio frequency module is provided with a radio frequency input power detection circuit, a radio frequency output power detection circuit, a module monitoring circuit, a power amplification circuit and a radio frequency digital controlled attenuator. The soft program running in the processor of the module monitoring circuit adjusts parameters of the radio frequency module according to querying predefined compensation table or according to the compensation data calculated based on predefined formula/algorithm, thus reducing influence of ambient temperature to linearity, gain, radio frequency power detection accuracy of the radio frequency module, as well as avoiding gain decrease of the radio frequency module. Moreover, a radio frequency module improved by such method is also provided. As said structure of above mentioned method is employed by the radio frequency module, monitoring method according to this structure is able to automatically debugging and testing by using tools such as computer, thus improving the production efficiency. | 08-19-2010 |
Yali Wang, Daqing CN
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20120310025 | Catalyst for Synthesizing 1-Hexene from Ethylene Trimerization and Application Thereof - A catalyst for synthesizing 1-hexene from ethylene trimerization and its application are provided. Said catalyst consists of (a) the compound containing P and N, (b) electron donor, (c) Cr compound, (d) carrier and (e) accelerator. The molar ratio of (a), (b), (c), (d) and (e) is 0.5-100:0.5-100:1:0.5-10:50-5000. The catalyst is prepared by mixing the components of (a)-(e) in an ethylene trimerization apparatus in situ and ethylene is introduced into the apparatus continuously. The prepared catalyst can be used to synthesize 1-hexene from ethylene trimerization in the inert solvents. The trimerization is performed at 30-150° C. and 0.5-10.0 MPa for 0.1-4 hours. The catalyst has high catalytic activity and high 1-hexene selectivity. During the process of ethylene trimerization, by-product polyethylene does not stick to the apparatus. | 12-06-2012 |
Yali Yang, Point Claire CA
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20140378605 | Poly[[2,6-4,8-di(5-ethylhexylthienyl)benzo[1,2-b;3,3-b]dithiophene][3-fluo- ro-2[(2-ethylhexyl)carbonyl]thieno[3,4-b]thiophenediyl]] - Preparation and application of poly[[2,6′-4,8-di(5-ethylhexylthienyl)benzo[1,2-b;3,3-b]dithiophene][3-fluoro-2[(2-ethylhexyl)carbonyl]thieno[3,4-b]thiophenediyl]] as a semiconducting polymer. | 12-25-2014 |
Yali Zhang, Xiamen CN
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20120301449 | RNA INTERFERENCE TARGET FOR TREATING AIDS - The RNAi target sequences, which could be used for treating AIDS through targeting HIV. Based on the target sequences, recombinant expression vectors, packaging vectors and cells were constructed, which express siRNA and/or miRNA and/or ribozyme and/or antisense oligonucleotide for targeting HIV. And the applications of said recombinant expression vectors, packaging vectors and cells in preparing medicament for treating AIDS. | 11-29-2012 |
Yali Zhang, Shanyang County CN
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20100044192 | Low Voltage Apparatus Having Mechanical Interlocking Means - A low voltage electrical appliance having a mechanical interlock means comprises at least two contactors, wherein every contactor includes a base ( | 02-25-2010 |
Yali Zhang, Fujian Province CN
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20110243904 | RNA INTERFERENCE TARGET FOR TREATING AIDS - The present invention relates to RNA interference target sequence targeting HIV for the treatment of AIDS. Based on the target sequence, recombinant expression vectors, packaging vectors and cells were constructed, which express a siRNA and/or a miRNA and/or a ribozyme and/or an antisense oligonucleotide targeting HIV. Also provided is the use of the recombinant expression vectors, packaging vectors and recombinant cells in the manufacture of a medicament for the treatment of AIDS. | 10-06-2011 |
Yali Zhang, Beijing CN
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20100286451 | Process for producing 1,2-dialkoxy-3-fluorobenzene - The present invention relates to a process for producing a 2-fluoro-6-halophenol as an intermediate; a process for producing a 2-alkoxy-3-fluorophenol and further a 1,2-dialkoxy-3-fluorobenzene from the 2-fluoro-6-halophenol; a second process for producing a 1,2-dialkoxy-3-fluorobenzene from the 2-fluoro-6-halophenol; and a 2-alkoxy-3-fluorophenol. The 2-fluoro-6-halophenol can be obtained using a 2-fluorophenol as a starting material and through a sulfonation reaction, a halogenation reaction, and a deprotection reaction. The 2-fluoro-6-halophenol is alkyl-etherified, and subsequently the halogen atom is converted into a hydroxyl group to obtain the 2-alkoxy-3-fluorophenol, which is further alkyl-etherified to thereby obtain the 1,2-dialkoxy-3-fluorobenzene. Alternatively, a 1,2-dialkoxy-3-fluorobenzene is also obtained by converting the halogen atom of the 2-fluoro-6-halophenol into a hydroxyl group to thereby form 3-fluorocatechol and subsequently alkyl-etherifying two hydroxyl groups thereof. The processes of the invention realize low production costs and high process yields, and thus are suitable for industrial production of a 1,2-dialkoxy-3-fluorobenzene. | 11-11-2010 |
Yali Zhao, Bejing CN
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20120213151 | METHOD, SYSTEM AND DEVICE FOR TRANSMITTING RANDOM ACCESS PREAMBLE - A method, a system and a device for sending a random access preamble are provided. The method includes: a base station determines an uplink component carrier to be utilized by a terminal for sending a random access preamble, and sends identification information of the uplink component carrier to the terminal ( | 08-23-2012 |
Yali Zhu, Foster City, CA US
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20090106306 | SQL Execution Plan Baselines - Approaches, techniques, and mechanisms are disclosed for maintaining a set of baseline query plans for a database command. Except in rare circumstances, a database server may only execute a command according to a baseline plan, even if the database server predicts that a different plan has a lower cost. The set of baseline plans are plans that, for one reason or another, have been determined to provide acceptable actual performance in at least one execution context. When the database server receives a request to execute a particular command, the database server, if possible, always executes the command according to the lowest predicted cost baseline plan. The database server may evolve the plan baseline to include additional plans by generating and testing new plans in response to new requests to execute the database command, or as part of a query optimization or tuning process. | 04-23-2009 |
20090106321 | Maintaining and Utilizing SQL Execution Plan Histories - Approaches, techniques, and mechanisms are disclosed for maintaining a history of query plans executed for a database command, along with information related to each query plan. A database server receives a request to execute a particular command. The database server determines a plan for executing the particular command. The database server adds first information to a plan history associated with the particular command. The plan history comprises information related to a plurality of plans that have been generated for the particular command. The first information may include, for example, properties of the plan (including an outline of the plan) as well as statistics collected during execution of the plan. The database server may implement techniques for periodically refreshing information in a plan history. The database server may also implement techniques for purging old or less important plans. | 04-23-2009 |
20120047158 | METHOD AND SYSTEM FOR PERFORMING QUERY OPTIMIZATION USING A HYBRID EXECUTION PLAN - An improved method, system, and computer program product is disclosed that provides a hybrid approach to optimization which allows different subsets of data accessed by a query to be optimized with different access paths and execution approaches. Transformations may be performed to re-write the query, which restructures the query in a way that facilitates the hybrid optimization process. Multiple transformations may be interleaved to produce an efficient re-written query. | 02-23-2012 |
20150088857 | METHOD AND SYSTEM FOR PERFORMING QUERY OPTIMIZATION USING A HYBRID EXECUTION PLAN - An improved method, system, and computer program product is disclosed that provides a hybrid approach to optimization which allows different subsets of data accessed by a query to be optimized with different access paths and execution approaches. Transformations may be performed to re-write the query, which restructures the query in a way that facilitates the hybrid optimization process. Multiple transformations may be interleaved to produce an efficient re-written query. | 03-26-2015 |