Xu, WI
Dapeng P. Xu, Madison, WI US
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20090022196 | HIGH EFFICIENCY INTERSUBBAND SEMICONDUCTOR LASERS - An intersubband quantum cascade laser structure includes multiple coupled laser stages, wherein each stage has a multilayer structure including an electron injector, an active region with at least one quantum well, and an electron reflector. Electrons injected from the injector into the active region at a high energy level relax to a lower energy level with the emission of a photon at, for example, mid-infrared wavelengths. The reflector reflects electrons at the higher energy level at which they were injected and transmits electrons from the lower energy level after emission of a photon. Multiple layers of semiconductor are formed on each side of the multistage structure to provide conduction across the device and to provide optical confinement of the photons emitted. | 01-22-2009 |
Fangmin Xu, Madison, WI US
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20080293906 | BIOACTIVE AND BIOCOMPATIBLE POLYURETHANE-BUTHANEDIOL-GLYCOSAMINOGLYCAN SALT COPOLYMERS - A bioactive and biocompatible polyurethane-butanediol-glycosaminoglycan copolymer for use in medical implant devices. The biocompatible urethane component being the reaction product of 4,4′-methylene-di-(p-phenyl isocyanate) and poly(tetramethylene oxide)n and further reacted with 1,4-butanediol, wherein n=10 to 40. The bioactive glycosaminoglycan being a salt of hyaluronic acid, such as a cetylpyridinium salt acid having 5 to 10,000 repeating units or a salt of heparin, such as a dimethyldioctadecylammonium salt of heparin has 5 to 65 repeating units or a suitable salt of dermatan sulfate. The weight content of the bioactive glycosaminoglycan is an amount sufficient to render the copolymer bioactive. The copolymers described herein have excellent hemocompatibility and biocompatibility. | 11-27-2008 |
20090062834 | ANEURYSM OCCLUSION DEVICE CONTAINING BIOACTIVE AND BIOCOMPATIBLE COPOLYMER SHELL AND BIOCOMPATIBLE METALLIC FRAME MEMBER - An endovascular device for occluding a vascular aneurysm is disclosed. The device includes a polymeric shell member that, in one embodiment, may be constructed from a bioactive and biocompatible polyurethane-diol-glycosaminoglycan copolymer, and a biocompatible metallic frame member. The copolymer is sufficiently flexible and strong for endovascular delivery into a vascular aneurysm and for use as a polymeric shell for receiving the biocompatible metallic frame member. The biometallic frame member may include one or more components constructed from a NiTi alloy. | 03-05-2009 |
20090118761 | ANEURYSM OCCLUSION DEVICE CONTAINING BIOACTIVE AND BIOCOMPATIBLE COPOLYMER SHELL AND A LIQUID EMBOLIC AGENT - An endovascular device for occluding a vascular aneurysm is disclosed. The device includes a polymeric shell member that, in one embodiment, may be constructed from a bioactive and biocompatible polyurethane-diol-glycosaminoglycan copolymer, and a liquid embolic agent. The copolymer is sufficiently flexible and strong for endovascular delivery into a vascular aneurysm and for use as a polymeric shell for receiving the liquid embolic agent. Upon activation inside of the polymeric shell within the aneurysm, the liquid embolic agent solidifies enabling biological isolation of the aneurysm and improved patient outcomes. | 05-07-2009 |
Fangmin Xu, Middleton, WI US
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20100113828 | MULTI-ARMED CATECHOL COMPOUND BLENDS - The invention describes families of compounds that utilize multihydroxyl phenyl groups to provide adhesive properties. Selection of the multihydroxy phenyl group along with linkers or linking groups and the linkages between the linkers or linking groups with polyalkylene oxides, provides materials that can be engineered to afford controllable curing time, biodegradation and/or swelling. | 05-06-2010 |
20100137902 | BIOADHESIVE CONSTRUCTS - The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons. | 06-03-2010 |
20100137903 | BIOADHESIVE CONSTRUCTS - The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons. | 06-03-2010 |
Guolin Xu, Milwaukee, WI US
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20120301382 | METAL AMIDOBORANE COMPOSITIONS AND PROCESSES FOR THEIR PREPARATION - The present invention provides compositions comprising a metal amidoborane and an amine, and processes for preparing the metal amidoborane compositions. In particular, the process comprises contacting ammonia borane with a metal amide in the presence of an amine solvent to form the metal amidoborane composition. The invention also provides methods for generating hydrogen, wherein the method comprises heating the metal amidoborane composition such that hydrogen is released. | 11-29-2012 |
Huifang Xu, Madison, WI US
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20080223713 | Photocatalyst Having Improved Quantum Efficiency and Method for Use in Photocatalytic and Photosynthetic - The present invention involves increasing the quantum efficiency in titania photocatalysts for photocatalytic (oxidation of acetaldehyde) and photosynthetic (photosplitting of water) reactions by integrating the titania photocatalyst with a polar mineral having surface electrical fields due to pyroelectric and piezoelectric effects, and by adjusting the nanostructure of the photocatalyst materials. The photocatalytic reactivity of titania powder is increased due to the effect of electric field present on the surface of polar mineral material on the photocatalytic effect of commercial titania with respect to photolysis of water. Additionally, the photocatalytic performance of pure phase rutile and anatase nanostructures with well defined morphologies was found to improved with respect to certain photocatalytic reactions in comparison with non-structured titania. | 09-18-2008 |
20100012479 | Mechanism for Direct-Water-Splitting Via Piezoelectrochemical Effect - A mechanism of initiating a redox reaction, such as hydrogen gas production by direct-water-splitting, is provided in which a piezoelectric material is mechanically stressed by actively applying a mechanical stress to the material. The mechanical stress applied to the piezoelectric material causes an electrical potential build up on the surface of the material due to the piezoelectric properties of the material. When the piezoelectric material stressed in this manner is placed in direct contact with the redox reaction reactant(s), the potential on the polarized surface can be used as chemical driving energy to initiate the reaction, such as to split water and generate hydrogen gas. In this manner the mechanical energy applied to the piezoelectric material, such as vibration energy from natural or man-made sources, can be converted directly into chemical energy to initiate the reaction. | 01-21-2010 |
Jiaquan Xu, Madison, WI US
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20130236352 | NANOMATERIAL-BASED METHODS AND APPARATUSES - Nanomaterials are incorporated within a material, such as within a metal-based material. As may be implemented in accordance with various embodiments, nanomaterials are introduced to a metal-based material in a liquid state, and the metal-based material and nanomaterials are cooled from the liquid state to a viscous state. The metal-based material is stirred in the viscous state to disperse the nanomaterials therein, and the metal-based material is used in the viscous state to maintain dispersion of the nanomaterials as the metal-based material cools. | 09-12-2013 |
20160060730 | NANOPARTICLE-STABILIZED IMMISCIBLE ALLOYS - Solid immiscible alloys and methods for making the solid immiscible alloys are provided. The microstructure of the immiscible alloys is characterized by a minority phase comprising a plurality of particles of an inorganic material dispersed in a majority phase comprising a continuous matrix of another inorganic material. The methods utilize nanoparticles to control both the collisional growth and the diffusional growth of the minority phase particles in the matrix during the formation of the alloy microstructure. | 03-03-2016 |
Ming Jun Xu, Madison, WI US
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20160092364 | MANAGEMENT OF STORAGE SYSTEM - In an approach for managing a storage system, distribution of storage volumes among a plurality of storage controller groups may be adjusted dynamically or adaptively based on the current access hot degrees of respective storage volumes in the storage system. In this way, optimized distribution of storage volumes can be achieved without user interference. Such redistribution eliminates the degradation of performance of the storage system. | 03-31-2016 |
Qingge Xu, Madison, WI US
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20100093102 | MESOPOROUS METAL OXIDE MATERIALS FOR PHOSPHOPROTEOMICS - The present invention provides methods and materials for isolating, purifying, and/or enriching the concentration of compounds having one or more phosphate groups and/or derivatives thereof, including but not limited to phosphorylated peptides and/or phosphorylated proteins. In some aspects, the present invention provides nanostructured enrichment materials, such as metal oxide mesoporous materials, that selectively and reversibly bind with phosphorylated compounds with high specificity and are capable of controlled release of phosphorylated compounds bound to their active surfaces. Mesoporous materials of the present invention also provide enrichment materials having large active surface areas that provide for higher loading capacities for phosphorylated peptides and proteins relative to conventional affinity based methods. Nanostructured metal oxide mesoporous enrichment materials of the present invention are also compatible with implementation via a variety of separation platforms including flow through separation systems, elution based separation systems, column chromatography and affinity chromatography. | 04-15-2010 |
Ren-He Xu, Madison, WI US
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20090029464 | Feeder Independent Extended Culture of Embryonic Stem Cells - Previous methods for culturing human embryonic stem cells have required either fibroblast feeder cells or a medium which has been exposed to fibroblast feeder cells in order to maintain the stem cells in an undifferentiated state. It has now been found that if an antagonist of bone morphogenic protein is added to the medium in which the stem cells are cultured, together with fibroblast growth factor, the stem cells will remain undifferentiated indefinitely, even without feeder cells or conditioned medium. | 01-29-2009 |
20150267165 | METHOD FOR GENERATING PRIMATE TROPHOBLASTS - The first method to cause a culture of human and other primate stem cells to directly and uniformly differentiate into a committed cell lineage is disclosed. Treatment of primate stem cells with a single protein trophoblast induction factor causes the cells to transform into human trophoblast cells, the precursor cells of the placenta. Several protein factors including bone morphogenic protein 4 (BMP4), BMP2, BMP7, and growth and differentiation factor 5 can serve as trophoblast-inducting factors. | 09-24-2015 |
Xiaofang Xu, Madison, WI US
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20110081720 | METHOD OF DIFFERENTIATING STEM CELLS INTO CELLS OF THE ENDODERM AND PANCREATIC LINEAGE - Methods are described to more efficiently produce cells of the endoderm and pancreatic lineage from mammalian pluripotent stem cells. These methods provide a simple, reproducible culture protocol using defined media components to enable consistent, large-scale production of pancreatic cell types for research or therapeutic uses. | 04-07-2011 |
20120264209 | METHODS AND DEVICES FOR DIFFERENTIATING PLURIPOTENT STEM CELLS INTO CELLS OF THE PANCREATIC LINEAGE - Methods and devices for culturing human pluripotent stem cells to produce cells of the pancreatic lineage are disclosed. The methods include steps of culturing the stem cells under conditions that induce the expression of mesendoderm/primitive streak and definitive endoderm markers in a chemically defined medium including an effective amount of i) fibroblast growth factor, ii) Activin A, and iii) bone morphogenetic protein. The methods further include the steps of culturing cells under conditions favoring the formation of at least one of intact embryoid bodies and pancreatic progenitor PDX1 | 10-18-2012 |
20140329315 | Methods for Producing Insulin-Secreting Beta Cells From Human Pluripotent Stem Cells - A method of culturing human pluripotent stem cells to produce pancreatic lineage, the method comprising the steps of (a) culturing the stem cells in the presence of a chemically defined medium comprising an effective amount of FGF, Activin A, and BMP; (b) culturing the cells from step (a) in the presence of a chemically defined medium comprising an effective amount of insulin, transferrin, and selenium (ITS), and FGF; (c) culturing the cells from step (b) in the presence of a chemically defined medium comprising an effective amount of insulin, transferrin, and selenium (ITS), and Noggin-Nicotinamide-Retinoic acid; and (d) culturing the cells from step (c) in the presence of a serum free chemically defined medium (ITSFINE and Noggin) comprising an effective amount of ITS, FGF7, islet neogenesis associated peptide (INGAP), nicotinamide, and Exendin-4, wherein pancreatic lineage cells are produced, wherein the pancreatic lineage cells are insulin | 11-06-2014 |