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Xu, CT
Fengting Xu, New Haven, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090155559 | Coated article with nanolayered coating scheme - A coated article that includes a substrate and a wear-resistant coating scheme. The coated article may be a cutting insert shown to improve performance in chip-forming material removal operations or a wear-resistant component used in chipless forming operations. The wear-resistant coating scheme has an underlayer and top layer containing aluminum, chromium, and nitrogen. The coating scheme also includes a mediate multi-periodicity nanolayer coating scheme containing titanium, aluminum, chromium and nitrogen. The mediate multi-periodicity nanolayer coating scheme includes a plurality of sets of alternating layer arrangements. Each one of the alternating layer arrangements has a base layer comprising titanium, aluminum and nitrogen and a nanolayer region having a plurality of sets of alternating nanolayers. Each set of alternating nanolayers has one nanolayer having aluminum, chromium, titanium and nitrogen and another nanolayer having aluminum, chromium, titanium and nitrogen. The base layer has a base layer thickness and the nanolayer region has a nanolayer region thickness. The base layer thickness is smaller than the nanolayer region thickness. | 06-18-2009 |
Gengfu Xu, Danbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100266932 | FUEL CELL WITH ELECTRICAL SHORT CIRCUIT PREVENTION MEANS - A fuel cell including an electrolyte matrix having a cathode side with a cathode disposed thereon and an anode side with an anode receiving portion and a sealing portion positioned peripherally to the anode receiving portion. The anode receiving portion has an anode disposed thereon. A fuel conduit has one or more one sealing platforms and having an opening extending through the fuel conduit. The anode is positioned in the opening. | 10-21-2010 |
Hai Xu, New Haven, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110265656 | METHOD AND APPARATUS FOR AIR PURIFICATION - An air purification device that is decorative and effective in removing contaminants from indoor air. The air purification device includes a carbon matrix composite. | 11-03-2011 |
Jianchao Xu, Bethany, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100136651 | DETECTION, ISOLATION AND USES OF RENALASE (MONOAMINE OXIDASE C) - The present invention provides for the identification, isolation and uses of mammalian Monoamine Oxidase C (MAO-C), also known as renalase. | 06-03-2010 |
| 20110081421 | METHODS OF REGULATING RENALASE (MONOAMINE OXIDASE C) - The present invention provides methods of using Monoamine Oxidase C (MAO-C), also known as renalase, as a therapeutic protein in its active and inactive forms. Administering inactive renalase protein to individuals with lower renalase levels can be used to provide them with an adequate pool of the protein that can be activated by the body as needed. Active renalase protein can be administered to individuals needing an immediate reduction of catecholamine levels. An inhibitor of renalase may be used to enhance adrenergic action. | 04-07-2011 |
Jianjun Xu, Branford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090069347 | 2-phenoxy pyrimidinone analogues - 2-Phenoxy pyrimidinone analogues are provided, of the Formula: | 03-12-2009 |
| 20090082330 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF - Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable vehicle chosen from carriers, adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described. | 03-26-2009 |
| 20100152159 | IMIDAZOPYRAZINE SYK INHIBITORS - Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample. | 06-17-2010 |
| 20100222323 | IMIDAZOPYRAZINE SYK INHIBITORS - Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample. | 09-02-2010 |
| 20110059944 | Certain Substituted Amides, Method of Making, and Method of Use Thereof - Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable vehicle chosen from carriers, adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described. | 03-10-2011 |
Jianjun Xu, Madison, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110118233 | Certain Substituted Amides, Method of Making, and Method of Use Thereof - Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable vehicle chosen from carriers, adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described. | 05-19-2011 |
| 20110301145 | PYRIDAZINONES, METHOD OF MAKING, AND METHOD OF USE THEREOF - Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable vehicle chosen from carriers, adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described. | 12-08-2011 |
| 20120010191 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE - Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. | 01-12-2012 |
Jinghua Xu, Danbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080293972 | Process for Preparing Substituted Anisidines - Disclosed is a process for preparing substituted anisidines of formula I starting from substituted cyclic hydroxy-ketones II via aromatization through a substituted oxime intermediate IV in which R is C | 11-27-2008 |
| 20080312473 | Two Step Process for Preparing Substituted Anisidines - The process of the present invention can be briefly summarized as depicted in the following scheme: R | 12-18-2008 |
Jinquan Xu, Tolland, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120026259 | LIQUID FILM MOVING OVER SOLID CATCHER SURFACE - A printhead includes a jetting module that forms liquid drops travelling along a first path. A deflection mechanism causes selected liquid drops formed by the jetting module to deviate from the first path and begin travelling along a second path. A catcher includes a liquid outlet, a stationary surface, and a liquid source that causes a liquid film to exit the liquid outlet and flow over the stationary surface of the catcher. The catcher is positioned relative to the first path such that the liquid drops travelling along one of the first path and the second path contact the liquid film. | 02-02-2012 |
| 20120026260 | PRINTING USING LIQUID FILM SOLID CATCHER SURFACE - A method of printing includes providing liquid drops travelling along a first path using a jetting module. A catcher including a liquid outlet, a stationary surface, and a liquid source is also provided. A liquid film provided by the liquid source is caused to exit the liquid outlet of the catcher and flow over the stationary surface of the catcher. Selected liquid drops are caused to deviate from the first path and begin travelling along a second path using a deflection mechanism such that the liquid drops travelling along one of the first path and the second path contact the liquid film. | 02-02-2012 |
Ningning Xu, Wallingford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110077280 | Hepatitis C Virus Inhibitors - This disclosure concerns novel compounds of Formula (I) as defined in the specification and compositions comprising such novel compounds. These compounds are useful antiviral agents, especially in inhibiting the function of the NS5A protein encoded by Hepatitis C virus (HCV). Thus, the disclosure also concerns a method of treating HCV related diseases or conditions by use of these novel compounds or a composition comprising such novel compounds. | 03-31-2011 |
| 20110286961 | Hepatitis C Virus Inhibitors - The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection. | 11-24-2011 |
Ren-He Xu, Farmington, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100173410 | Cultivation of Primate Embryonic Stem Cells - The invention relates to methods for culturing human embryonic stem cells by culturing the stem cells in an environment essentially free of mammalian fetal serum and in a stem cell culture medium including amino acids, vitamins, salts, minerals, transferrin, insulin, albumin, and a fibroblast growth factor that is supplied from a source other than just a feeder layer the medium. Also disclosed are compositions capable of supporting the culture and proliferation of human embryonic stem cells without the need for feeder cells or for exposure of the medium to feeder cells. | 07-08-2010 |
Tian Xu, Guilford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100154070 | PiggyBac as a Tool for Genetic Manipulation and Analysis in Vertebrates - The present invention relates to transgenic vertebrate, including mammalian, cells, whose genomes comprise one or more elements of the piggyBac family transposon system. Transgenic non-human vertebrates, including transgenic non-human mammals, whose genomes comprise one or more elements of the piggyBac family transposon system, are also provided. Methods of making and using the cells and animals of the invention, including applications in the medical, veterinary, and agricultural fields, are additionally provided. The present invention also relates to kits useful for practicing such methods. | 06-17-2010 |
Xiangqing Xu, Meriden, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080212500 | Systems and Methods of Efficient Band Amplification - Systems and methods for multi-band amplification. In an exemplary embodiment of the present invention, the multi-band amplification device has an uplink amplifier with a first port and a second port and a downlink amplifier with a first port and a second port. Furthermore, the multi-band amplification device has a first duplexer device in communication with the first port of the downlink amplifier and the second port of the uplink amplifier and a second duplexer device in communication with the first port of the uplink amplifier and the second port of the downlink amplifier. The first duplexer device is enabled to receive and transmit at least a downlink signal and an uplink signal of a first frequency band, a downlink signal and an uplink signal of a second frequency band, and a downlink signal and an uplink signal of a third frequency band. The second duplexer device is enabled to receive and transmit at least the downlink signal and the uplink signal of the first frequency band, the downlink signal and the uplink signal of the second frequency band, and the downlink signal and the uplink signal of the third frequency band. | 09-04-2008 |
| 20080212502 | Systems and Methods of Band Amplification with a Shared Amplifier - The present invention provides systems and methods for band amplification with a shared amplifier. In an exemplary embodiment, the wireless band amplification device has with an amplifier with an input port and an output port. The wireless band amplification device also provides two circulators, the first circulator in communication with the input port of the amplifier and the second circulator in communication with the output port of the amplifier. Additionally, two duplexer devices are provided in communication with both circulators. The input port of the amplifier is enabled to receive at least a first frequency band downlink signal and a first frequency band uplink signal. In an alternate embodiment, the input port of the amplifier can be further adapted to receive a second frequency band downlink signal and a second frequency band uplink signal. Additionally, the input port of the amplifier can be further adapted to receive a third frequency band downlink signal and a third frequency band uplink signal. | 09-04-2008 |
Yibo Xu, New Milford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090088571 | Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides - Disclosed is a multi-step process for preparing a compound of Formula I: | 04-02-2009 |
| 20100317848 | PROCESS FOR THE SYNTHESIS OF DERIVATIVES OF 3-AMINO-TETRAHYDROFURAN-3-CARBOXYLIC ACID AND USE THEREOF AS MEDICAMENTS - The present invention relates to a process for the manufacturing of substituted 3-amino-tetrahydrofuran-3-carboxylic acid amides of general formula (I) and their precursors in high optical purity to the precursors of the synthesis of substituted S-Amino-tetrahydrofuran-S-carboxylic acid amides of general formula (I) in high optical purity, and to the tautomers, enantiomers, diastereomers, mixtures and salts of substituted 3-amino-tetrahydrofuran-3-carboxylic acid amides of general formula (I) in high optical purity, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties. | 12-16-2010 |
Yuelian Xu, Newington, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100317679 | SUBSTITUTED ARYL-FUSED SPIROCYCLIC AMINES - Substituted Aryl-fused Spirocyclic Amines of the formula (I): are provided, as are methods for their preparation and use. Such compounds may generally be used to modulate ligand binding to histamine H3 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and therapeutic methods are provided, as are methods for using such ligands for detecting histamine H3 receptors (e.g., receptor localization studies). | 12-16-2010 |
Yuelian Xu, East Haven, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080247964 | SUBSTITUTED AZASPIRO DERIVATIVES - Substituted azaspiro derivatives of the Formula: | 10-09-2008 |
| 20090023737 | Imidazo-Pyridazines, Triazolo-Pyridazines and Related Benzodiazepine Receptor Ligands - Compounds of the Formula: | 01-22-2009 |
| 20110002855 | PIPERAZINYL OXOALKYL TETRAHYDRO-BETA-CARBOLINES AND RELATED ANALOGUES - Piperazinyl oxoalkyl tetrahydro-beta-carbolines and related analogues of the formula (I): are provided, as are methods for their preparation and use. Such compounds may generally be used to modulate ligand binding to histamine H3 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and therapeutic methods are provided, as are methods for using such ligands for detecting histamine H3 receptors (e.g., receptor localization studies). | 01-06-2011 |
| 20110082130 | PIPERAZINYL OXOALKYL TETRAHYDROISOQUINOLINES AND RELATED ANALOGUES - Piperazinyl oxoalkyl tetrahydroisoquinolines and related analogues of the Formula: | 04-07-2011 |