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Xie, MI
Mark M. Xie, Saint Joseph, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100241276 | METHOD AND APPARATUS FOR MONITORING LOAD SIZE AND LOAD IMBALANCE IN A WASHING MACHINE - A method of determining static and dynamic imbalance conditions in a horizontal axis washing machine utilizes a number of dynamic algorithms to automatically determine the total load size, the magnitude of any static load imbalance, and the magnitude of any dynamic load imbalance for any given load in a given washing machine based on power measurements from the washing machine motor obtained in predetermined speed profiles. | 09-23-2010 |
| 20120144874 | LAUNDRY TREATING APPLIANCE WITH BALANCING SYSTEM - A laundry treating appliance having a drum, defining a treating chamber, with a lifter and a balancing system having at least one balancing ring and a reservoir located in the lifter and a liquid supply system fluidly coupled to the reservoir. Liquid may be supplied to the ring and to the reservoir through the ring to offset an imbalance in a laundry load located within the drum. | 06-14-2012 |
Qian Xie, Grand Rapids, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20120100157 | Biomarker and Method for Predicting Sensitivity to MET Inhibitors - Methods for determining the responsiveness of a Met-related cancer in a subject to treatment with a Met inhibitor. Kits for performing the disclosed methods are also provided. The present invention also provides a method of treating glioblastomamultiforme (GBM) in a subject in need thereof, the method comprises administering a therapeutically effective dose of a Met inhibitor in combination with a therapeutically effective dose of a epithelial growth factor receptor (EGFR) inhibitor. | 04-26-2012 |
Tao Xie, Benton Harbor, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110041564 | HEAT PUMP (SERVER) COUPLED WASHER AND DRYER PAIR - An appliance system that includes an appliance group containing at least two appliances, a first appliance designed to perform a first consumer function related to the first appliance and a second appliance that is separate from the first appliance and designed to perform a second consumer function related to the second appliance. The appliance system also includes a thermal energy generator, typically a heat pump, where the thermal energy heats at least one thermal energy bearing fluid and is operably connected to the first and second appliances to deliver thermal energy to the first and second appliances simultaneously or at different times via one or more of the thermal energy bearing fluids. | 02-24-2011 |
Tao Xie, Saint Joseph, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100241276 | METHOD AND APPARATUS FOR MONITORING LOAD SIZE AND LOAD IMBALANCE IN A WASHING MACHINE - A method of determining static and dynamic imbalance conditions in a horizontal axis washing machine utilizes a number of dynamic algorithms to automatically determine the total load size, the magnitude of any static load imbalance, and the magnitude of any dynamic load imbalance for any given load in a given washing machine based on power measurements from the washing machine motor obtained in predetermined speed profiles. | 09-23-2010 |
Wenhua Xie, Novi, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090246819 | Assay Methods Using Chemiluminescent Detection of Peroxidase - Methods for generating chemiluminescence rapidly by reaction of at least one compound comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups with a peroxidase enzyme and a peroxide are disclosed. The chemiluminescence thus produced can be used as a detectable signal in assays for peroxidase enzymes or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs. Use of the methods provides rapid signal generation, achieving a plateau intensity in under one minute. The substrate can be provided in a composition which demonstrates unexpectedly long storage stability. | 10-01-2009 |
| 20100173429 | METHODS USING NOVEL CHEMILUMINESCENT LABELS - Methods using chemiluminescent label compounds and chemiluminescent labeled conjugates are provided. The compounds comprise an acridan ring bearing an exocyclic ketene dithioacetal group and further contain a labeling substituent which permits attachment to compounds of interest. The novel chemiluminescent compounds and labeled conjugates are convenient to prepare, are highly stable, and generate chemiluminescence rapidly on demand. The compounds and conjugates are useful in assays of an analyte in a sample and in assays employing labeled specific binding pairs. | 07-08-2010 |
| 20100190271 | METHODS USING NOVEL CHEMILUMINESCENT LABELS - Methods using chemiluminescent label compounds and chemiluminescent labeled conjugates are provided. The compounds comprise an acridan ring bearing an exocyclic ketene dithioacetal group and further contain a labeling substituent which permits attachment to compounds of interest. The novel chemiluminescent compounds and labeled conjugates are convenient to prepare, are highly stable, and generate chemiluminescence rapidly on demand. The compounds and conjugates are useful in assays of an analyte in a sample and in assays employing labeled specific binding pairs. | 07-29-2010 |
| 20100267071 | SOLUTION PHASE HOMOGENEOUS ASSAYS - Methods, reagents, kits and systems are disclosed for determining an analyte in a sample suspected of containing the analyte where all reagents are soluble in aqueous solution. One assay method includes treating a sample suspected of containing the analyte under conditions such that if the analyte is present, an activator is brought into reactive configuration with a chemiluminescent compound to activates it. The sample is also treated with an agent to reduce signal not related to analyte. Finally, the sample is treated with a trigger solution thereby producing light from the activated chemiluminescent compound. No reagents are associated with a surface or other solid phase. | 10-21-2010 |
| 20100273189 | NON SEPARATION ASSAYS WITH SELECTIVE SIGNAL INHIBITORS - Methods, reagents, kits and systems are disclosed for determining an analyte in a sample, the assay method comprising forming a reaction mixture in an aqueous solution, by adding a chemiluminescent-labeled immobilized specific binding member, an activator-labeled specific binding member, a selective signal inhibiting agent, and a sample, wherein the chemiluminescent-labeled immobilized specific binding member and activator-labeled specific binding member bind to analyte present in the sample to form a binding complex, and adding to the reaction mixture a trigger solution to release a detectable chemiluminescent signal correlated to the amount of the analyte-bound binding complex present in the reaction mixture. | 10-28-2010 |
Yiping Xie, Ann Arbor, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110015902 | Twelve-Cornered Strengthening Member - A method for optimizing a twelve-cornered strengthening member comprises: modeling a vehicle assembly including a strengthening member having a twelve-cornered cross section; parameterizing a geometry of the strengthening member with a plurality of control parameters; defining a design of experiment using the plurality of control parameters; modeling a vehicle using the vehicle assembly; simulating a frontal impact event with the vehicle; generating a response surface based on the frontal impact event; and determining a set of optimized control parameters for the strengthening member based on the response surface. | 01-20-2011 |
Zhe Xie, Rochester, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20120159939 | ELECTRIC PUMP - A system for lubricating transmission components with hydraulic fluid includes a pump and a motor coupled to the pump. The pump has an inlet port that receives hydraulic fluid and an outlet port from which hydraulic fluid is pumped to the transmission components. A pump pressure is regulated by adjusting a motor torque of the motor, and the motor torque is set by commands based on a look-up table or a formula. | 06-28-2012 |
Zhe Xie, Auburn Hills, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100326542 | CONTROL SYSTEM FOR AN AUTOMATIC TRANSMISSION HAVING MULTIPLE DEFAULT MODES - A hydraulic control system for a automatic transmission includes a plurality of solenoids and valves in fluid communication with a plurality of shift actuators. The shift actuators are operable to actuate a plurality of torque transmitting devices. Selective activation of combinations of the solenoids allows for a pressurized fluid to activate at least one of the shift actuators. The solenoids are configured to provide a forward gear ratio and a reverse gear ratio when the solenoids are deengerized. | 12-30-2010 |
| 20110131969 | TRANSMISSION HYDRAULIC CONTROL SYSTEM HAVING INDEPENDENTLY CONTROLLED STATOR COOLING FLOW - A hydraulic control system includes a source of pressurized hydraulic fluid for providing a pressurized hydraulic fluid, a main line circuit in fluid communication with the source of pressurized hydraulic fluid, a regulation valve in communication with the source of pressurized hydraulic fluid, the regulation valve moveable between a plurality of positions, and a lubrication valve in communication with the regulation valve, the lubrication valve moveable between a plurality of positions. A lubrication circuit and a cooling circuit are in communication with the lubrication valve. The regulation valve allows pressurized hydraulic fluid to communicate with the lubrication valve after the main line circuit is saturated, the lubrication valve allows fluid communication between the regulation valve and the lubrication circuit until the lubrication circuit is saturated, and the lubrication valve allows fluid communication between the regulation valve and the cooling circuit and the lubrication circuit after the lubrication circuit is saturated. | 06-09-2011 |
Zijian Xie, Saline, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100056446 | NA+K+-ATPase-Specific Peptide Inhibitors/Activators of SRC and SRC Family Kinases - A method for regulating Src and its downstream signaling pathway which includes binding between Src and Na+/K+-ATPase is disclosed. The Na+/K+-ATPase/Src complex is a functional receptor for cardiotonic steroids such as ouabain. Also disclosed are Src inhibitors or activators which include either Na+/K+-ATPase or Src that interfere with the interaction between the Na/K-ATPase and Src, act via a different mechanism from ATP analogues, and is pathway (Na+/K+-ATPase) specific. | 03-04-2010 |
Zi-Jian Xie, Saline, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110245167 | NaK-ATPase-Derived Peptide SRC Inhibitors and Ouabain Antagonists and Uses Thereof - A novel Src inhibitor that targets the Na/K-ATPase/Src receptor complex and antagonizes ouabain-induced protein kinase cascades and uses thereof are disclosed. | 10-06-2011 |
| 20110306570 | Na/K-Atpase Expression as an Indicator for the Treatment of Cancer - Methods for regulating the expression of Na/K-ATPase and uses thereof, including uses in the diagnosis/prognosis and treatment of cancer, are disclosed. | 12-15-2011 |