Patent application number | Description | Published |
20080293744 | Enantiomers of Selected Fused Pyrimidones and Uses in the Treatment and Prevention of Cancer - This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer. | 11-27-2008 |
20080306096 | Quinazoline Derivatives, Process for Their Preparation and Their Use as Anti-Cancer Agents - The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man. | 12-11-2008 |
20080312206 | Chemical Compounds-149 - The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man. | 12-18-2008 |
20090012084 | 3-CINNOLINECARBOXAMIDE DERIVATIVES AND THEIR USE FOR TREATING CANCER - The invention relates to chemical compounds of formula (I): | 01-08-2009 |
20090054411 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS - The invention relates to chemical compounds of formula IA or IB: | 02-26-2009 |
20090099210 | ENANTIOMERS OF SELECTED FUSED HETEROCYCLICS AND USES THEREOF - This invention relates to novel compounds having the structural formula (I) | 04-16-2009 |
20090118261 | QUINAZOLINONE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS - The invention relates to chemical compounds of the formula (I): or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man. | 05-07-2009 |
20090270450 | CHEMICAL COMPOUNDS - The invention relates to chemical compounds of formula (I): | 10-29-2009 |
20110098283 | 3-CINNOLINECARBOXAMIDE DERIVATIVES AND THEIR USE FOR TREATING CANCER - The invention relates to chemical compounds of formula (I): | 04-28-2011 |
20110218182 | CHEMICAL COMPOUNDS 251 - The invention relates to chemical compounds of formula (I), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of PIM kinase related conditions and diseases, preferably cancer. | 09-08-2011 |
20150051185 | Chemical Compounds 251 - The invention relates to chemical compounds of formula I, | 02-19-2015 |