Patent application number | Description | Published |
20090161931 | IMAGE REGISTRATION SYSTEM AND METHOD - A method and system for registering two images is described. The method comprises synthesizing projections from two volumetric images to be registered, estimating a plurality of two dimensional (2D) deformable fields from the projections and generating a three dimensional (3D) deformable fields using a plurality of backprojections of the 2D deformable fields. | 06-25-2009 |
20090245598 | Methods for Assessing Molecular Expression of Subcellular Molecules - The present techniques provide fully automated methods for quantifying the location, strength and percent of expressed target molecules or other biological markers in immunohistochemically stained biological samples. The samples may be automatically segmented, for example into subcellular compartments, from images of compartmental markers. Then, the distribution of a target molecule on each of these compartments is calculated that includes the percentage and strength of expression. This is different than existing intensity or ratio based methods where abundant low expression levels are indistinguishable from scarce high expression levels. | 10-01-2009 |
20090245610 | Method and Apparatus for Detecting Irregularities in Tissue Microarrays - The present techniques provide systems and methods for registering images of tissue spots on a tissue microarray (TMA). In studies involving multiple biomarkers being studied on the same TMA, the TMA slide is removed from the microscope, stained, and then imaged, often multiple times. The present techniques relate to validation of the registration of the acquired images of the same TMA. An automatic approach to register the images and detect registration failures as provided herein may enhance the rapid analysis of the tissues. Artifacts such as tissue folding and tissue loss are also determined automatically. | 10-01-2009 |
20090245611 | Method and Apparatus for Removing Tissue Autofluorescence - Techniques for removing image autoflourescence from fluorescently stained biological images are provided herein. The techniques utilize non-negative matrix factorization that may constrain mixing coefficients to be non-negative. The probability of convergence to local minima is reduced by using smoothness constraints. The non-negative matrix factorization algorithm provides the advantage of removing both dark current and autofluorescence. | 10-01-2009 |
20090247416 | Method and Apparatus for Analysis of Tissue Microarrays - The present techniques include methods and systems for finding correspondences between tissue spots in tissue microarray serial sections belonging to the same recipient block. The present techniques may also be used to relate individual tissue cores to clinical information. Using either a whole slide image or the relative x-y coordinates of the tissue spots on the slide, individual tissue spots in different tissue microarrays may be linked to one another and their clinical information. | 10-01-2009 |
20100124369 | METHODS AND APPARATUS FOR MEASURING 3D DIMENSIONS ON 2D IMAGES - A method for determining 3D distances on a 2D pixelized image of a part or object includes acquiring a real 2D pixelized image of the object, creating a simulated image of the object using the 3D CAD model and the 2D pixelized image, determining a specified cost function comparing the simulated image with the real 2D pixilated image and repositioning the simulated image in accordance with iterated adjustments of a relative position between the CAD model and the XID pixilated image to change the simulated image until the specified cost function is below a specified value. Then, the workstation is used to generate a 3D distance scale matrix using the repositioned simulated image, and to measure and display distances between selected pixels on a surface of the real image using 2D distances on the 2D pixelized image of the object and the 3D distance scale matrix. | 05-20-2010 |
20100129005 | SYSTEM AND METHOD FOR AUTOMATED SCAN PLANNING USING SYMMETRY DETECTION AND IMAGE REGISTRATION - A method of determining an anatomically consistent scan protocol for an object of interest includes obtaining a volumetric image of an object of interest to be imaged, transforming the volumetric image, estimating the position and orientation of the object using the volumetric image and the transformed volumetric image, and modifying the imaging scan protocol using the estimated object position and orientation. | 05-27-2010 |
20100130849 | SYSTEM AND METHOD FOR PATIENT MOTION COMPENSATION DURING MAGNETIC RESONANCE SCANS - A method for motion compensation includes acquiring an initial volumetric localizer to establish an initial object position and initial object orientation at an initial state, acquiring a fast localizer of the object at a present state, aligning the fast localizer to the initial volumetric localizers to determine object motion between the initial state and the present state, and modifying an imaging protocol using the object position and orientation at the present state. | 05-27-2010 |
20100220908 | SYSTEM AND METHOD FOR PROCESSING DATA SIGNALS - A signal processing method include steps initializing a residual data signal representative of an acquired data signal, determining a significant coefficient corresponding to the residual data signal, updating the residual data signal using the significant coefficient to generate updated residual data signal, iteratively determining significant coefficients to generate a plurality of significant coefficients using the updated residual data signal, updating the plurality of significant coefficients by using a successive approximation technique, to improve the numerical accuracy of the significant coefficients and reconstructing a data signal using the updated plurality of significant coefficients. | 09-02-2010 |
20100220910 | METHOD AND SYSTEM FOR AUTOMATED X-RAY INSPECTION OF OBJECTS - An anomaly detection method and system for comparing a scanned object to an idealized object is provided. The anomaly detection method includes generating a three-dimensional reference model of the idealized object. The anomaly detection method further includes acquiring at least one two-dimensional inspection test image of the scanned object. The anamoly detection method also includes determining a two-dimensional reference image from the three-dimensional reference model using multiple pose parameters, wherein the two-dimensional reference image corresponds to the same view of the three-dimensional reference model of the idealized object as the view of the two-dimensional inspection test image of the scanned object. The anamoly detection method further includes identifying one or more defects in the inspection test image via automated defect recognition technique. | 09-02-2010 |
20110054317 | TRACKING AND OPTIMIZING GAIN AND CONTRAST IN REAL-TIME FOR ULTRASOUND IMAGING - A system for dynamic optimization of gain and contrast in ultrasound imaging includes an image processor module programmed to dynamically estimate a correction profile in real-time and apply the correction profile to adjust a gain and contrast of image frame data sets. The image processor module is programmed to identify tissue and background regions in an image frame data set, determine an image intensity for each of the tissue and background regions, and formulate a gain profile based on the image intensity of the tissue region to compensate the gain variation of an image. The image processor module is further programmed to calculate an image contrast metric based on the image intensity of the tissue and background regions, and modify a gray map of the image frame data set based on the image contrast metric to adjust the contrast of an image displayed on the display system. | 03-03-2011 |
20110228998 | SYSTEM AND METHOD FOR AUTOMATIC COMPUTATION OF MR IMAGING SCAN PARAMETERS - A system and method for automatic computation of MR imaging scan parameters include a computer programmed to acquire a first set of MR data from an imaging subject, the first set of MR data comprising a plurality of slices acquired at a first field-of-view. The computer is also programmed to reconstruct the plurality of slices into a plurality of localizer images and identify a 3D object based on the plurality of localizer images. The computer is further programmed to prescribe a scan, execute the prescribed scan to acquire a second set of MR data, and reconstruct the second set of MR data into an image. The prescribed scan includes one of a reduced field-of-view based on a boundary of the 3D object and a shim region based on the boundary of the 3D object. | 09-22-2011 |
20130090946 | SYSTEMS AND METHODS FOR IMAGING WORKFLOW - An imaging workflow system includes a workstation for acquiring patient information and requesting a patient scan. The request for a patient scan includes scan information for performing the scan. A registration module receives the scan information and the patient information. The registration module automatically schedules the patient scan based on the scan information and the patient information. The registration module determines an imaging protocol based on the patient information and the scan information. An imaging module within an imaging system receives the imaging protocol. The imaging module automatically sets scan parameters based on the imaging protocol. The imaging system scans the patient based on the scan parameters to acquire image data. A user interface controls the patient scan. The user interface includes a display to display images generated from the acquired image data. | 04-11-2013 |
20130279779 | SYSTEMS AND METHODS FOR LANDMARK CORRECTION IN MAGNETIC RESONANCE IMAGING - Systems and methods for landmark correction in Magnetic Resonance Imaging (MRI) are provided. One method includes acquiring at least one calibration image or at least one localizer image of an object, identifying in the calibration or localizer images a region of the object as a reference point, wherein the reference point defines a landmark position. The method further includes determining an offset between an initial landmark position and the identified landmark position. The method also includes using the determined offset for MRI. | 10-24-2013 |