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Wu, MA
Aiwen Wu, Malden, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090045140 | Method and apparatus for treating fluids to reduce microbubbles - Versions of the invention include methods for reducing microbubbles in liquids treated by heat or mass exchange devices. The exchange devices may be conditioned by having gases in crevices and surfaces displaced by a liquid. The methods can be used to prepare liquids with reduced numbers of microbubbles. | 02-19-2009 |
Artie Wu, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090069798 | EYE THERAPY SYSTEM - A system for applying therapy to an eye selectively applies coolant to the corneal surface to minimize heat-related damage to the corneal surface during thermokeratoplasty. Embodiments may include an energy source, a conducting element, a coolant supply, and a coolant delivery system. The conducting element is operably connected to the energy source and extends from a proximal end to a distal end. The conducting element directs energy from the energy source to the distal end, which is positionable at the eye. The coolant delivery system is in communication with the coolant supply and is operable to deliver a micro-controlled pulse of coolant to the distal end. | 03-12-2009 |
| 20090209954 | SYSTEM AND METHOD FOR RESHAPING AN EYE FEATURE - A system for applying therapy to an eye includes an applicator having a conducting element configured to direct energy from an energy source to an application end of the conducting element, where the application end has at least one eye contact portion. A positioning system positions the at least one eye contact portion in stable engagement with the eye surface. The conducting element is disposed within a housing for the applicator and at least one adjustment system is employed to move the conducting element relative to the housing. The at least one adjustment system enables controlled movement of the conducting element and the at least one eye contact portion against the corneal surface. In particular embodiments, sufficient contact between the applicator and the cornea is determined by causing applanation of the cornea. In other embodiments, at least one measurement device is employed to determine when sufficient contact has been established. | 08-20-2009 |
Chao-Ting Wu, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100304994 | Oligonucleotide Paints - Novel methods for making high resolution oligonucleotide paints are provided. Novel, high resolution oligonucleotide paints are also provided. | 12-02-2010 |
Chi Hang Wu, Quincy, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110275981 | ELECTRODE ASSEMBLY FOR DELIVERING A THERAPEUTIC AGENT INTO OCULAR TISSUE - A contact electrode assembly for delivering at least one therapeutic agent into ocular tissue of a subject includes a flexible dielectric layer, a first electrode portion, and a second electrode portion. The flexible dielectric includes oppositely disposed first and second surfaces. The first electrode portion is disposed on the first surface of the dielectric layer. The second electrode portion is disposed on a portion of the second surface of the dielectric layer. The second electrode portion includes an interdigitated electrode having a first comb-shaped portion defining a first plurality of fingers and a second comb-shaped portion defining a second plurality of fingers. Each of the first electrode portion, the first comb-shaped portion, and the second comb-shaped portion is electrically connectable to a signal source. | 11-10-2011 |
Chin-Cheng Wu, Carlisle, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120004960 | METHOD AND SYSTEM FOR EFFICIENT STREAMING VIDEO DYNAMIC RATE ADAPTATION - A streaming media system employs dynamic rate adaptation. The method includes a file format compatible with legacy HTTP infrastructure to deliver media over a persistent connection. The method further includes the ability for legacy client media players to dynamically change the encoded delivery rate of the media over a persistent connection. The method provided works transparently with standard HTTP servers, requiring no modification and leverages standard media players embedded in mobile devices for seamless media delivery over wireless networks with high bandwidth fluctuations. A system is also specified for implementing a client and server in accordance with the method. | 01-05-2012 |
| 20120005364 | SYSTEM AND METHOD FOR NETWORK AWARE ADAPTIVE STREAMING FOR NOMADIC ENDPOINTS - In a system for streaming data over a network, the type and rate of streaming are automatically varied based on available network bandwidth. Video media is transcoded into different bit rate encodings that are divided into segment files. Segments are sent from a network-aware adaptive streaming (NAAS) server and reassembled and presented to a media player at a client device. The system may download additional segment files ahead of time from multiple NAAS servers to increase throughput. A playback status (“bookmark”) may be maintained to keep track of what the user has viewed and to allow the user to continue playing from where the user left off. The user may continue watching from the bookmark point on the same device or on a different device. | 01-05-2012 |
| 20120005365 | METHOD AND SYSTEM FOR EFFICIENT STREAMING VIDEO DYNAMIC RATE ADAPTATION - A streaming media system employs dynamic rate adaptation. The method includes a file format compatible with legacy HTTP infrastructure to deliver media over a persistent connection. The method further includes the ability for legacy client media players to dynamically change the encoded delivery rate of the media over a persistent connection. The method provided works transparently with standard HTTP servers, requiring no modification and leverages standard media players embedded in mobile devices for seamless media delivery over wireless networks with high bandwidth fluctuations. A system is also specified for implementing a client and server in accordance with the method. | 01-05-2012 |
Frank Xinhe Wu, Shrewsbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110166146 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS - Imidazo[1,2-a]pyridines are disclosed. Compounds of the invention are useful therapeutic agents and their inclusion in pharmaceutical formulations and use in methods of treatment are disclosed. | 07-07-2011 |
| 20110319380 | Compounds for Treating Disorders Mediated by Metabotropic Glutamate Receptor 5, and Methods of Use Thereof - Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein. | 12-29-2011 |
Guangxiang Wu, Waltham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090261247 | Linear Ion Trap with Four Planar Electrodes - A rectilinear ion trap includes a first pair of spaced planar RF electrodes, mounted in parallel and a second pair of spaced planar electrodes, mounted in parallel and orthogonal to the first pair of electrodes. The configuration of the pairs of electrodes define an axial direction and a radial direction. The trap further includes an RF source that applies an RF voltage to at least one of the pairs of RF electrodes to generate RF fields to trap ions in the axial and radial directions. | 10-22-2009 |
Haiou Wu, West Roxbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090049599 | Passive sensors for automatic faucets and bathroom flushers - The present invention is directed to novel optical sensors and novel methods for sensing optical radiation. The novel optical sensors and the novel optical sensing methods are used, for example, for controlling the operation of automatic faucets and flushers. The novel sensors and flow controllers (including control electronics and valves) require only small amounts of electrical power for sensing users of bathroom facilities, and thus enable battery operation for many years. A passive optical sensor includes a light detector sensitive to ambient (room) light for controlling the operation of automatic faucets or automatic bathroom flushers. | 02-26-2009 |
| 20100024895 | System and method for converting manually operated flush valves - Disclosed is a method and system for converting or retrofitting manually-operated flush valves. A conversion system for converting an installed manually-operated flush valve includes a power module, a control module, and a driver module mechanically coupled to a manual handle to externally activate the converted flush valve. | 02-04-2010 |
| 20100275359 | Optical sensors and algorithms for controlling automatic bathroom flushers and faucets - The present invention is directed to novel optical sensors and novel methods for sensing optical radiation that can be used to control the operation of automatic faucets and flushers. The novel sensors and flow controllers require only small amounts of electrical power for sensing users of bathroom facilities, enabling battery operation for many years. An electronic system for controlling fluid flow may include an electromagnetic actuator, a controller and an optical sensor. Preferred embodiments include a control circuit constructed to sample periodically the detector based on the amount of light detected; a control circuit constructed to adjust a sample period based on the detected amount of light after determining whether a facility is in use; a detector optically coupled to the input port using an optical fiber; the input port may be located in an aerator of the electronic faucet; the system includes batteries for powering the electronic faucet. These embodiments may also include a variety of other features. A passive optical sensor includes a light detector sensitive to ambient (room) light for controlling the operation of automatic faucets or automatic bathroom flushers. An active optical sensor includes a light emitter and a light detector. The detected signals may be processed using novel algorithms | 11-04-2010 |
| 20100327197 | Passive sensors for automatic faucets and bathroom flushers - The present invention is directed to novel optical sensors and novel methods for sensing optical radiation. The novel optical sensors and the novel optical sensing methods are used, for example, for controlling the operation of automatic faucets and flushers. The novel sensors and flow controllers (including control electronics and valves) require only small amounts of electrical power for sensing users of bathroom facilities, and thus enable battery operation for many years. A passive optical sensor includes a light detector sensitive to ambient (room) light for controlling the operation of automatic faucets or automatic bathroom flushers. | 12-30-2010 |
| 20110302708 | Passive sensors and control algorithms for faucets and bathroom flushers - An optical system includes one or several passive optical detectors sensitive to ambient (room) light for controlling, for example, the operation of automatic faucets or automatic bathroom flushers. The passive optical sensors provide signals to flow controllers, including control electronics and flow valves and require only very small amounts of electrical power for sensing users of bathroom facilities, and thus enable battery operation for many years. To control the operation of automatic faucets or automatic bathroom flushers based on ambient light, the controller executes novel algorithms. | 12-15-2011 |
Haoquan Wu, Jamaica Plain, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100209440 | Targeted Delivery of siRNA - The present invention provides a method of delivering RNA interference molecules to a cell or a cell in a subject, which comprises contacting the cell with a protein-double stranded RNA complex, the complex comprising the double stranded RNA segment containing a double stranded RNA of interest and a protein, the protein comprising (1) a targeting moiety, which will specifically bind to a site on a target cell, and (2) a binding moiety linked thereto, which will bind to the double stranded RNA, wherein the double stranded RNA segment is delivered to a cell and effects RNA interference of the target RNA in the cell. | 08-19-2010 |
Henry Wu, Brighton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100041975 | PATIENT MONITORING SYSTEMS AND METHODS - Various systems and methods are provided for monitoring patient physiological data without the need for adhesives or wires to be connected to a patient. The system is also fully functional without the need for manipulation or intervention by a care provider or medical personnel. In particular, the system can include a pad having a plurality of electrical contacts or electrodes formed thereon in a predetermined pattern. The electrodes can be configured to sense electrical signals produced by a patient's body. A controller in communication with the electrodes can be configured to select and process signals from the electrodes and send the information derived from the electrical signals to an output device for displaying resulting physiological data so that the patient can be monitored. | 02-18-2010 |
Jianxiong Wu, Acton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090055182 | Discriminative Training of Hidden Markov Models for Continuous Speech Recognition - Methods are given for improving discriminative training of hidden Markov models for continuous speech recognition. For a mixture component of a hidden Markov model state, a gradient adjustment is calculated of the standard deviation of the mixture component. If the calculated gradient adjustment is greater than a first threshold amount, an adjustment is performed of the standard deviation of the mixture component using the first threshold. If the calculated gradient adjustment is less than a second threshold amount, an adjustment is performed of the standard deviation of the mixture component using the second threshold. Otherwise, an adjustment is performed of the standard deviation of the mixture component using the calculated gradient adjustment. | 02-26-2009 |
Jiayi Wu, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090291998 | EPONEMYCIN AND EPOXOMICIN ANALOGS AND USES THEREOF - The present invention provides compounds having formula (1): wherein R | 11-26-2009 |
Joyce H. Wu, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090195855 | MECHANICAL LIGHT MODULATORS WITH STRESSED BEAMS - The invention relates to a spatial light modulator including a substrate having a surface and a modulation assembly coupled to the substrate including a modulation element and a compliant beam. The modulation assembly is configured to limit the bending of the compliant beam towards an opposing surface that would otherwise be caused by inherent stresses within the compliant beam. The invention also relates to a method of manufacturing a spatial light modulator including the steps of forming and releasing a modulation assembly that has a modulation element and a compliant beam formed in a pre-release position to have an intended inherent stress state. As a result of the stress state in the compliant beam, upon release of the compliant beam, the compliant beam bends into a rest position which is different than the pre-release position, where the rest position is based in part on the intended inherent stress state. | 08-06-2009 |
| 20100110518 | MEMS ANCHORS - The invention relates to an improved apparatus and method for the design and manufacture of MEMS anchoring structures for light modulators in order to address the stresses of beams mounted on them. | 05-06-2010 |
| 20110157679 | METHODS FOR MANUFACTURING COLD SEAL FLUID-FILLED DISPLAY APPARATUS - This methods and devices described herein relate to displays and methods of manufacturing cold seal fluid-filled displays, including MEMS. The fluid substantially surrounds the moving components of the MEMS display to reduce the effects of stiction and to improve the optical and electromechanical performance of the display. The invention relates to a method for sealing a MEMS display at a lower temperature such that a vapor bubble does not formforms only at temperatures about 15° C. to about 20° C. below the seal temperature. In some embodiments, the MEMS display apparatus includes a first substrate, a second substrate separated from the first substrate by a gap and supporting an array of light modulators, a fluid substantially filling the gap, a plurality of spacers within the gap, and a sealing material joining the first substrate to the second substrate. | 06-30-2011 |
Jun Jun Wu, Arlington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100137298 | Biaryl Sulfonamides and Methods for Using Same - The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors. | 06-03-2010 |
Kevin (kuo-Ming) Wu, Acton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110237805 | INTERMEDIATES AND METHODS FOR MAKING ZEARALENONE MACROLIDE ANALOGS - Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R | 09-29-2011 |
Laurence Wu, Woburn, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090163537 | Thienopyridinone Compounds and Methods of Treatment - The invention relates to 5-HT receptor agonists and partial agonists. Novel thienopyridinone compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, nonulcer dyspepsia, depression, anxiety, urinary incontinence, migraine, arrhythmia, atrial fibrillation, ischemic stroke, gastritis, gastric emptying disorders, feeding disorders, gastrointestinal disorders, constipation, erectile dysfunction, and respiratory depression. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included. | 06-25-2009 |
| 20110195953 | COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS - The invention generally relates to thienopyridinone 5-HT | 08-11-2011 |
Lisa Wu, South Easton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110274771 | Prenatal Syptomatic Kit - A medication kit includes a plurality of individual non-prophylactic, non-urgent care symptomatic treatments configured to treat the symptoms of a pre-existing medical condition such as pregnancy. The treatments include a combination of pharmaceutical treatments and non-pharmaceutical treatments corresponding to particular symptoms often associated with the pre-existing condition. Each of the pharmaceutical treatments are configured for mutually independent dosage, and are predetermined by an authoritative organization such as the Food and Drug Administration to be safe for use at the mutually independent dosages, in combination with one another by otherwise healthy patients having the pre-existing medical condition, without expectation of adverse side effects. | 11-10-2011 |
Lushen Wu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100192066 | METHOD AND SYSTEM FOR A GRAPHICAL USER INTERFACE - A method of providing capabilities for searching a plurality of audio files by a graphical user interface in a display. A window showing information concerning at least one of a plurality of audio files is configured to operate in an always-on-top mode within the user interface, while occupying an area that is substantially less than 10% of the display's overall area. The window provides a search entry element configured to receive at least one search criterion provided by a user, the search criterion established by the user to identify at least one audio file from among the plurality of audio files. Additional unobtrusive windows are provided in the same user interface to present the results of search actions, these additional windows being initialized as hidden, and visible when a user initiates a search action or actively engages the search results. | 07-29-2010 |
Miaochen Wu, Acton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110298508 | DATA INTERFACE WITH DELAY LOCKED LOOP FOR HIGH SPEED DIGITAL TO ANALOG CONVERTERS AND ANALOG TO DIGITAL CONVERTERS - A system comprises a first circuit includes a data transmitter circuit that transmits digital data based on a first clock signal. A sync generator outputs a sync signal based on the first clock signal. A digital to analog converter circuit includes a data receiver circuit that latches the digital data based on a second clock signal. A digital to analog converter core receives an output of the data receiver circuit. A delay locked loop circuit determines a delay based on the second clock signal and the sync signal and outputs the first clock signal to the first circuit based on the second clock signal and the delay. | 12-08-2011 |
Ona Wu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100030071 | DELAY-COMPENSATED CALCULATION OF TISSUE BLOOD FLOW - Methods for computing perfusion parameters are described. The methods are typically used to analyze magnetic resonance (MR) and other image data and to calculate tissue perfusion parameters such as blood flow in the brain or in tissues in other organs such as the heart. The methods employ a block-circulant matrix for deconvolving the perfusion parameters from the image data. | 02-04-2010 |
Qi-Long Wu, Brighton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080213251 | HK1-BINDING PROTEINS - The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides. | 09-04-2008 |
Qunwei Wu, Westford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100295225 | METHOD AND APPARATUS FOR FLUID PROCESSING A WORKPIECE - A method of fluid sealing a workpiece is provided. The method includes placing a workpiece on a ring, engaging at least one engagement feature of the ring with at least one retaining feature defined by the member and flexing the member to provide a force to the at least one engagement feature to cause the ring to form a barrier to fluid entry with the workpiece. | 11-25-2010 |
| 20100301564 | BALANCING PRESSURE TO IMPROVE A FLUID SEAL - A method of fluid sealing a workpiece is provided. The method includes providing a force to cause a ring to form a barrier to fluid entry with the workpiece and preventing fluid from crossing the barrier to fluid entry by forming a pressure differential across the barrier. | 12-02-2010 |
| 20110139627 | METHOD AND APPARATUS FOR FLUID PROCESSING A WORKPIECE - A method of fluid processing a semiconductor workpiece, including disposing a workpiece holder with a housing capable of containing a fluid, the workpiece holder retaining the workpiece, providing an agitation system connected to the housing and comprising a member disposed within the housing adjacent the workpiece holder, and agitating the fluid by moving the member substantially parallel to a surface of the workpiece with a non-uniform oscillatory motion, the non-uniform oscillatory motion being a series of substantially continuous geometrically asymmetric oscillations wherein each consecutive oscillation of the series is geometrically asymmetric having at least two substantially continuous opposing strokes wherein reversal positions of each substantially continuous stroke of the substantially continuous asymmetric oscillation are disposed asymmetrically with respect to a center point of each immediately preceding substantially continuous stroke of the oscillation. | 06-16-2011 |
Shiaw-Lin Wu, Weston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080280317 | Comprehensive Characterization Of Complex Proteins At Trace Levels - A combination of “bottom up” and “top down” MS analysis of posttranslational modifications in complex proteins is described. The method comprises digestion of the protein with an enzyme that forms larger peptide fragments than trypsin (>3000 D), performing HPLC with the fragments and applying a new data acquisition strategy using on-line coupling with e.g. LTQ-FTMS, a hybrid mass spectrometer that couples a linear ion trap with a Fourier transform ion cyclotron resonance (FTICR) cell. The method is applied to analysis of posttranslational modifications of protein isoforms. | 11-13-2008 |
| 20090221430 | Proteomic Methods For The Identification And Use Of Putative Biomarkers Associated With The Dysplastic State In Cervical Cells Or Other Cell Types - The invention relates to methods for detecting and identifying potential biomarkers of high-grade cervical dysplasia in an individual human subject. The invention also relates to newly discovered biomarkers, as set forth in Tables 1-4 herein, which are associated with the dysplastic state of cervical cells. It has been discovered that a differential level of expression of any of these markers or combination of these markers correlates with a dysplastic condition in a human subject, e.g., a patient. | 09-03-2009 |
Steven Wu, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110172692 | HEMODIALYSIS ARTERIO-VENOUS GRAFT WITH A RING-LIKE DIAMETER-ADJUSTABLE DEVICE - A ring device is integrated externally onto and around a regular hemodialysis arterio-venous graft conduit. The ring device is adjustable to reduce or to normalize (by rebounding) the diameter of the graft, and eventually to change blood flow through the graft. This ring device is designed such that it can be scaled up or down to change its diameter, and simultaneously the diameter of the associated graft prior to and even after its implantation into a patient's arm or leg. Since a hemodialysis arterio-venous graft is usually implanted superficially underneath skin, the device and its adjustable parts can be electively or urgently located and operated from outside by touching and pushing the skin, subcutaneous tissues and the device without a surgical incision. The ring device can be located anywhere within the graft and can function with a single ring or as a set of multiple rings. | 07-14-2011 |
Wengen Wu, Meford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090062235 | Inhibitors of Dipeptidylpeptidase IV - The present invention relates to inhibitors of post-proline cleaving enzymes, such as inhibitors of dipeptidyl peptidase IV, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. In particular, the inhibitors of the present invention are improved over those in the prior art by selection of particular classes of sidechains in the P1 and/or P2 position of the inhibitor that contain a carboxylic acid moiety. The compounds of the present invention can have a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. | 03-05-2009 |
Wengen Wu, Medford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090124559 | Soft Protease Inhibitors and Pro-Soft Forms Thereof - The invention provides compounds and methods for inhibiting proteases. One aspect of the invention features pro-soft inhibitors which react with an activating protease to release an active inhibitor moiety in proximity to a target protease. In certain instances, compounds inhibit proteasomes and/or post-proline cleaving enzymes (PPCE), such as dipeptidyl peptidase IV. The compounds of the invention provide a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. | 05-14-2009 |
| 20110218142 | Inhibitors of Dipeptidylpeptidase IV - The present invention relates to inhibitors of post-proline cleaving enzymes, such as inhibitors of dipeptidyl peptidase IV, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. In particular, the inhibitors of the present invention are improved over those in the prior art by selection of particular classes of sidechains in the P1 and/or P2 position of the inhibitor that contain a carboxylic acid moiety. The compounds of the present invention can have a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. | 09-08-2011 |
Xing-Tao Wu, Woburn, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080297311 | NON-CONTACT SERVICE PROVIDING SYSTEMS - A service providing system comprising a server device, a terminal device, and a service providing device in combination with an optical wireless tag device to achieve transmitting of ID, password, or other service information stored in the service providing device in a non-contact and non-broadcasting manner, thus enabling highly secured and reliable services. | 12-04-2008 |
Xunlei Wu, Quincy, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080273777 | Methods And Apparatus For Segmentation And Reconstruction For Endovascular And Endoluminal Anatomical Structures - Methods and apparatus for generating network of endoluminal surfaces by defining a set of medial axes for a tubular structure, defining a series of cross sections along medial axis in the set of medial axes, generating a connectivity graph of the medial axes, defining multiple surface representations based upon the graph of the medial axes and the cross sections, computing a volume defined by a first one of the surface representations, defining a partition of the medial axis, cross-sections, surface and/or volume representations, and outputting the network of endoluminal surfaces. | 11-06-2008 |
Yaming Wu, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080214655 | Paclitaxel enhancer compounds - Disclosed is a compound represented by the Structural Formula (I): | 09-04-2008 |
| 20080242702 | Paclitaxel enhancer compound - One embodiment of the present invention is a compound represented by the Structural Formula (I): | 10-02-2008 |
| 20100093670 | Compounds for the treatment of angiogenesis - The invention relates to isoxazole, isothiazole, and triazole compounds that are useful for treating or inhibiting angiogenesis. | 04-15-2010 |
| 20100280075 | PACLITAXEL ENHANCER COMPOUNDS - Disclosed is a compound represented by the Structural Formula (I): | 11-04-2010 |
| 20110059893 | COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS - The invention relates to compounds of structural formula (I): | 03-10-2011 |
Yang Wu, Reading, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110224128 | METHODS AND COMPOSITIONS FOR TREATMENT OF MUSCULAR DYSTROPHY - The invention features methods, compositions, and kits useful for the treatment of muscular dystrophy, e.g., Duchenne muscular dystrophy, in a patient. | 09-15-2011 |
Yecheng Wu, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110222081 | Printing Three-Dimensional Objects Using Hybrid Format Data - Methods of how to build a 3D model with both surface features and internal structures are disclosed. 3D image data in a hybrid data format or other suitable data formats are first received as input and then broken down into layers of 2D data. The layers of 2D data hold various attribute information about the model, such as colors, shapes, durometer hardness, etc. The layers of data are printed on printing sheets that are specially formulated. Selected materials are also deposited on printed sheets as dictated by the 2D data. Each printed sheet is cut along the shape boundaries either before or after it has been bound to previously printed sheets. Finished sheets are then bound and processed to generate a 3D model with rich details. | 09-15-2011 |
Yinan Wu, Westborough, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110182305 | Small Packaged Tunable Laser with Beam Splitter - According to one embodiment, the present application includes a tunable laser configured in a small package. The tunable laser includes a housing with a volume formed by exterior walls. An electrical input interface is positioned at the first end of the housing and configured to receive an information-containing electrical signal. An optical output interface is positioned at the second end of the housing and configured to transmit a continuous wave optical beam. A tunable semiconductor laser is positioned in the interior space and operable to emit a laser beam having a selectable wavelength. A focusing lens assembly is positioned in the interior space along an optical path of the laser beam to operatively couple the laser beam to the optical output interface. | 07-28-2011 |
Yuchuan Wu, Acton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100029648 | 11-Beta HSD1 Inhibitors - This invention relates to inhibiting 11βHSD1. | 02-04-2010 |
| 20100227859 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS - The present teachings relate to compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, R4, X, and Y are as defined herein. The present teachings also provide methods of making the compounds of formula I and methods of inhibiting matrix metalloproteinases, in particular, MMP-12, that may be involved in pathological disorders found in mammals, including a human. | 09-09-2010 |
Zhidan Wu, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090269332 | Human diacylglycerol acyltransferase 2 (DGAT2) family members and uses therefor - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 10-29-2009 |
| 20090281191 | USE OF ORGANIC COMPOUNDS - Use of a ERRγ agonist Or pharmaceutically acceptable salt thereof, for the prevention, delay of progression or the treatment of diabetes, insulin resistance, metabolic disease/metabolic syndrome, dyslipdemia, obesity, overweight, Neurodegenerative diseases such as Parkinson's disease. Alzheimer's disease, Huntington's disease or improvement of exercise endurance capacity. | 11-12-2009 |
| 20100035339 | HUMAN DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2) FAMILY MEMBERS AND USES THEREFOR - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 02-11-2010 |
| 20120003233 | HUMAN DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2) FAMILY MEMBERS AND USES THEREFOR - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 01-05-2012 |
Zhidan Wu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100104584 | GENES INVOLVED IN MITOCHONDRIAL BIOGENESIS - The invention discloses suitable gene and polypeptide targets for the development of new therapeutics to treat, prevent or ameliorate conditions associated with mitochondrial dysfunction. The invention also relates to methods to treat, prevent or ameliorate said conditions and pharmaceutical compositions therefor, as well as to a method to identify compounds with therapeutic usefulness to treat conditions associated with mitochondrial dysfunction. | 04-29-2010 |