Patent application number | Description | Published |
20120224755 | Single-Action Three-Dimensional Model Printing Methods - Methods and techniques of using 3D printers to create physical models from image data are discussed. Geometric representations of different physical models are described and complex data conversion processes that convert input image data into geometric representations compatible with third party 3D printers are disclosed. Printing templates are used to encapsulate complex geometric representations and complicated data conversion processes from users for fast and simple 3D physical model printing applications. | 09-06-2012 |
20130339487 | Method and Apparatus for URL Handling - Methods and apparatus for processing and handling URL are disclosed. A URL-action table is relied on for storing registered applications with corresponding domain names. The registered applications may differ from common web browsers. When a URL or the hypertext referring to a URL is clicked, the domain name included in the URL is extracted and used to search the URL-action table for the registered application. If the registered application is valid, the application is invoked. Otherwise, a default web browser is invoked. | 12-19-2013 |
20140330418 | SINGLE ACTION THREE-DIMENSIONAL MODEL PRINTING METHODS - Methods and techniques of using 3D printers to create physical models from image data are discussed. Geometric representations of different physical models are described and complex data conversion processes that convert input image data into geometric representations compatible with third party 3D printers are disclosed. Printing templates are used to encapsulate complex geometric representations and complicated data conversion processes from users for fast and simple 3D physical model printing applications. | 11-06-2014 |
20140330421 | SINGLE ACTION THREE-DIMENSIONAL MODEL PRINTING METHODS - Methods and techniques of using 3D printers to create physical models from image data are discussed. Geometric representations of different physical models are described and complex data conversion processes that convert input image data into geometric representations compatible with third party 3D printers are disclosed. Printing templates are used to encapsulate complex geometric representations and complicated data conversion processes from users for fast and simple 3D physical model printing applications. | 11-06-2014 |
20150084956 | Single Action Three-Dimensional Model Printing Methods - Methods and techniques of using 3D printers to create physical models from image data are discussed. Geometric representations of different physical models are described and complex data conversion processes that convert input image data into geometric representations compatible with third party 3D printers are disclosed. Printing templates are used to encapsulate complex geometric representations and complicated data conversion processes from users for fast and simple 3D physical model printing applications. | 03-26-2015 |
20150088291 | Single Action Three-Dimensional Model Printing Methods - Methods and techniques of using 3D printers to create physical models from image data are discussed. Geometric representations of different physical models are described and complex data conversion processes that convert input image data into geometric representations compatible with third party 3D printers are disclosed. Printing templates are used to encapsulate complex geometric representations and complicated data conversion processes from users for fast and simple 3D physical model printing applications. | 03-26-2015 |
Patent application number | Description | Published |
20090069798 | EYE THERAPY SYSTEM - A system for applying therapy to an eye selectively applies coolant to the corneal surface to minimize heat-related damage to the corneal surface during thermokeratoplasty. Embodiments may include an energy source, a conducting element, a coolant supply, and a coolant delivery system. The conducting element is operably connected to the energy source and extends from a proximal end to a distal end. The conducting element directs energy from the energy source to the distal end, which is positionable at the eye. The coolant delivery system is in communication with the coolant supply and is operable to deliver a micro-controlled pulse of coolant to the distal end. | 03-12-2009 |
20090209954 | SYSTEM AND METHOD FOR RESHAPING AN EYE FEATURE - A system for applying therapy to an eye includes an applicator having a conducting element configured to direct energy from an energy source to an application end of the conducting element, where the application end has at least one eye contact portion. A positioning system positions the at least one eye contact portion in stable engagement with the eye surface. The conducting element is disposed within a housing for the applicator and at least one adjustment system is employed to move the conducting element relative to the housing. The at least one adjustment system enables controlled movement of the conducting element and the at least one eye contact portion against the corneal surface. In particular embodiments, sufficient contact between the applicator and the cornea is determined by causing applanation of the cornea. In other embodiments, at least one measurement device is employed to determine when sufficient contact has been established. | 08-20-2009 |
20130131664 | Eye Therapy System - A system for applying therapy to an eye selectively applies coolant to the corneal surface to minimize heat-related damage to the corneal surface during thermokeratoplasty. Embodiments may include an energy source, a conducting element, a coolant supply, and a coolant delivery system. The conducting element is operably connected to the energy source and extends from a proximal end to a distal end. The conducting element directs energy from the energy source to the distal end, which is positionable at the eye. The coolant delivery system is in communication with the coolant supply and is operable to deliver a micro-controlled pulse of coolant to the distal end. | 05-23-2013 |
Patent application number | Description | Published |
20100304994 | Oligonucleotide Paints - Novel methods for making high resolution oligonucleotide paints are provided. Novel, high resolution oligonucleotide paints are also provided. | 12-02-2010 |
20120142540 | Methods For Sequencing Nucleic Acid Molecules - Methods and compositions for determining the nucleic acid sequence of polynucleotides that are at least 1500 nucleotides in length are provided. | 06-07-2012 |
20120295801 | High-Throughput In Situ Hybridization - Novel methods and compositions for providing high-throughput fluorescence in situ hybridization (FISH) are provided. | 11-22-2012 |
20130143208 | Oligonucleotide Trapping - Novel methods and compositions for identifying one or more factors associated with a nucleic acid sequence (e.g., DNA and/or RNA) of interest are provided. | 06-06-2013 |
20140113839 | Methods of Making Oligonucleotide Probes - The present invention relates to methods of making linear nucleic acid probes using rolling circle amplification methods. | 04-24-2014 |
20140272959 | Methods of Hybridizing Probes to Genomic DNA - The present invention relates to methods of hybridizing nucleic acid probes to genomic DNA. | 09-18-2014 |
20140272960 | Methods of Identifying Homologous Genes Using FISH - The present invention relates to methods of hybridizing nucleic acid probes to genomic DNA. | 09-18-2014 |
20140364333 | Methods for Live Imaging of Cells - The present invention relates to methods of hybridizing nucleic acid probes to genomic DNA. | 12-11-2014 |
Patent application number | Description | Published |
20120004960 | METHOD AND SYSTEM FOR EFFICIENT STREAMING VIDEO DYNAMIC RATE ADAPTATION - A streaming media system employs dynamic rate adaptation. The method includes a file format compatible with legacy HTTP infrastructure to deliver media over a persistent connection. The method further includes the ability for legacy client media players to dynamically change the encoded delivery rate of the media over a persistent connection. The method provided works transparently with standard HTTP servers, requiring no modification and leverages standard media players embedded in mobile devices for seamless media delivery over wireless networks with high bandwidth fluctuations. A system is also specified for implementing a client and server in accordance with the method. | 01-05-2012 |
20120005364 | SYSTEM AND METHOD FOR NETWORK AWARE ADAPTIVE STREAMING FOR NOMADIC ENDPOINTS - In a system for streaming data over a network, the type and rate of streaming are automatically varied based on available network bandwidth. Video media is transcoded into different bit rate encodings that are divided into segment files. Segments are sent from a network-aware adaptive streaming (NAAS) server and reassembled and presented to a media player at a client device. The system may download additional segment files ahead of time from multiple NAAS servers to increase throughput. A playback status (“bookmark”) may be maintained to keep track of what the user has viewed and to allow the user to continue playing from where the user left off. The user may continue watching from the bookmark point on the same device or on a different device. | 01-05-2012 |
20120005365 | METHOD AND SYSTEM FOR EFFICIENT STREAMING VIDEO DYNAMIC RATE ADAPTATION - A streaming media system employs dynamic rate adaptation. The method includes a file format compatible with legacy HTTP infrastructure to deliver media over a persistent connection. The method further includes the ability for legacy client media players to dynamically change the encoded delivery rate of the media over a persistent connection. The method provided works transparently with standard HTTP servers, requiring no modification and leverages standard media players embedded in mobile devices for seamless media delivery over wireless networks with high bandwidth fluctuations. A system is also specified for implementing a client and server in accordance with the method. | 01-05-2012 |
20120240176 | METHOD AND SYSTEM FOR FEDERATED OVER-THE-TOP CONTENT DELIVERY - A method is provided for managing over-the-top delivery of content through a plurality of content delivery networks (CDN). The method provided works transparently with standard HTTP servers supporting an initial request for content from a client to a first preferred CDN. If the first CDN does not have the content, the method includes provisions for the first CDN to acquire the content from a second CDN, or for the client to request the content from a second CDN directly. A system is also specified for implementing a client and server infrastructure in accordance with the provisions of the method. | 09-20-2012 |
20140047069 | METHOD AND SYSTEM FOR FEDERATED OVER-THE-TOP CONTENT DELIVERY - A method is provided for managing over-the-top delivery of content through a plurality of content delivery networks (CDN). The method provided works transparently with standard HTTP servers supporting an initial request for content from a client to a first preferred CDN. If the first CDN does not have the content, the method includes provisions for the first CDN to acquire the content from a second CDN, or for the client to request the content from a second CDN directly. A system is also specified for implementing a client and server infrastructure in accordance with the provisions of the method. | 02-13-2014 |
20150074831 | Method and System for Federated Over-the-Top Content Delivery - A method is provided for managing over-the-top delivery of content through a plurality of content delivery networks (CDN). The method provided works transparently with standard HTTP servers supporting an initial request for content from a client to a first preferred CDN. If the first CDN does not have the content, the method includes provisions for the first CDN to acquire the content from a second CDN, or for the client to request the content from a second CDN directly. A system is also specified for implementing a client and server infrastructure in accordance with the provisions of the method. | 03-12-2015 |
Patent application number | Description | Published |
20110166146 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS - Imidazo[1,2-a]pyridines are disclosed. Compounds of the invention are useful therapeutic agents and their inclusion in pharmaceutical formulations and use in methods of treatment are disclosed. | 07-07-2011 |
20110319380 | Compounds for Treating Disorders Mediated by Metabotropic Glutamate Receptor 5, and Methods of Use Thereof - Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein. | 12-29-2011 |
20130289013 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS - Imidazo[1,2-a]pyridines are disclosed. Compounds of the invention are useful therapeutic agents and their inclusion in pharmaceutical formulations and use in methods of treatment are disclosed. | 10-31-2013 |
20140179682 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF - Compounds that modulate GluR5 activity and methods of using the same are disclosed. | 06-26-2014 |
20140221332 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF - Compounds that modulate GluR5 activity and methods of using the same are disclosed. | 08-07-2014 |
20140349992 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF - Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein. | 11-27-2014 |
Patent application number | Description | Published |
20090049599 | Passive sensors for automatic faucets and bathroom flushers - The present invention is directed to novel optical sensors and novel methods for sensing optical radiation. The novel optical sensors and the novel optical sensing methods are used, for example, for controlling the operation of automatic faucets and flushers. The novel sensors and flow controllers (including control electronics and valves) require only small amounts of electrical power for sensing users of bathroom facilities, and thus enable battery operation for many years. A passive optical sensor includes a light detector sensitive to ambient (room) light for controlling the operation of automatic faucets or automatic bathroom flushers. | 02-26-2009 |
20100024895 | System and method for converting manually operated flush valves - Disclosed is a method and system for converting or retrofitting manually-operated flush valves. A conversion system for converting an installed manually-operated flush valve includes a power module, a control module, and a driver module mechanically coupled to a manual handle to externally activate the converted flush valve. | 02-04-2010 |
20100275359 | Optical sensors and algorithms for controlling automatic bathroom flushers and faucets - The present invention is directed to novel optical sensors and novel methods for sensing optical radiation that can be used to control the operation of automatic faucets and flushers. The novel sensors and flow controllers require only small amounts of electrical power for sensing users of bathroom facilities, enabling battery operation for many years. An electronic system for controlling fluid flow may include an electromagnetic actuator, a controller and an optical sensor. Preferred embodiments include a control circuit constructed to sample periodically the detector based on the amount of light detected; a control circuit constructed to adjust a sample period based on the detected amount of light after determining whether a facility is in use; a detector optically coupled to the input port using an optical fiber; the input port may be located in an aerator of the electronic faucet; the system includes batteries for powering the electronic faucet. These embodiments may also include a variety of other features. A passive optical sensor includes a light detector sensitive to ambient (room) light for controlling the operation of automatic faucets or automatic bathroom flushers. An active optical sensor includes a light emitter and a light detector. The detected signals may be processed using novel algorithms | 11-04-2010 |
20100327197 | Passive sensors for automatic faucets and bathroom flushers - The present invention is directed to novel optical sensors and novel methods for sensing optical radiation. The novel optical sensors and the novel optical sensing methods are used, for example, for controlling the operation of automatic faucets and flushers. The novel sensors and flow controllers (including control electronics and valves) require only small amounts of electrical power for sensing users of bathroom facilities, and thus enable battery operation for many years. A passive optical sensor includes a light detector sensitive to ambient (room) light for controlling the operation of automatic faucets or automatic bathroom flushers. | 12-30-2010 |
20110302708 | Passive sensors and control algorithms for faucets and bathroom flushers - An optical system includes one or several passive optical detectors sensitive to ambient (room) light for controlling, for example, the operation of automatic faucets or automatic bathroom flushers. The passive optical sensors provide signals to flow controllers, including control electronics and flow valves and require only very small amounts of electrical power for sensing users of bathroom facilities, and thus enable battery operation for many years. To control the operation of automatic faucets or automatic bathroom flushers based on ambient light, the controller executes novel algorithms. | 12-15-2011 |
20130145535 | Passive sensors for automatic faucets and bathroom flushers - The present invention is directed to novel optical sensors and novel methods for sensing optical radiation. The novel optical sensors and the novel optical sensing methods are used, for example, for controlling the operation of automatic faucets and flushers. The novel sensors and flow controllers (including control electronics and valves) require only small amounts of electrical power for sensing users of bathroom facilities, and thus enable battery operation for many years. A passive optical sensor includes a light detector sensitive to ambient (room) light for controlling the operation of automatic faucets or automatic bathroom flushers. | 06-13-2013 |
20130145536 | System and method for converting manually operated flush valves - A conversion system for converting an installed manually-operated flush valve used with a urinal or toilet is designed for automatic operation. The conversion system includes a power module, a control module, a driver module coupled to the manually-operated flush valve, and an optical sensor constructed to detect light arriving from a detection field. The control module is constructed to control activation of the driver module based on a signal from the optical sensor. | 06-13-2013 |
Patent application number | Description | Published |
20090195855 | MECHANICAL LIGHT MODULATORS WITH STRESSED BEAMS - The invention relates to a spatial light modulator including a substrate having a surface and a modulation assembly coupled to the substrate including a modulation element and a compliant beam. The modulation assembly is configured to limit the bending of the compliant beam towards an opposing surface that would otherwise be caused by inherent stresses within the compliant beam. The invention also relates to a method of manufacturing a spatial light modulator including the steps of forming and releasing a modulation assembly that has a modulation element and a compliant beam formed in a pre-release position to have an intended inherent stress state. As a result of the stress state in the compliant beam, upon release of the compliant beam, the compliant beam bends into a rest position which is different than the pre-release position, where the rest position is based in part on the intended inherent stress state. | 08-06-2009 |
20100110518 | MEMS ANCHORS - The invention relates to an improved apparatus and method for the design and manufacture of MEMS anchoring structures for light modulators in order to address the stresses of beams mounted on them. | 05-06-2010 |
20110157679 | METHODS FOR MANUFACTURING COLD SEAL FLUID-FILLED DISPLAY APPARATUS - This methods and devices described herein relate to displays and methods of manufacturing cold seal fluid-filled displays, including MEMS. The fluid substantially surrounds the moving components of the MEMS display to reduce the effects of stiction and to improve the optical and electromechanical performance of the display. The invention relates to a method for sealing a MEMS display at a lower temperature such that a vapor bubble does not formforms only at temperatures about 15° C. to about 20° C. below the seal temperature. In some embodiments, the MEMS display apparatus includes a first substrate, a second substrate separated from the first substrate by a gap and supporting an array of light modulators, a fluid substantially filling the gap, a plurality of spacers within the gap, and a sealing material joining the first substrate to the second substrate. | 06-30-2011 |
20120200906 | MEMS ANCHORS - The invention relates to an improved apparatus and method for the design and manufacture of MEMS anchoring structures for light modulators in order to address the stresses of beams mounted on them. | 08-09-2012 |
20130050290 | ELECTROMECHANICAL SYSTEM STRUCTURES WITH RIBS HAVING GAPS - This disclosure provides systems, methods and apparatus for an electromechanical systems (EMS) assembly. The EMS assembly includes a substrate, an anchor disposed on the substrate, and a suspended planar body supported over the substrate by the anchor. The suspended planar body includes at least one depression extending out of a plane of the suspended planar body and protruding towards the substrate. The suspended planar body also includes a substantially horizontal portion corresponding to a gap in the at least one depression. An extent of the gap is up to 20% of a length of the suspended planar body. | 02-28-2013 |
20130322058 | MICROELECTROMECHANICAL DEVICE AND METHOD OF MANUFACTURING - A display apparatus includes a backlight and an aperture layer that is positioned in front of the backlight and defines a plurality of apertures. The display apparatus also includes a microelectromechanical system (MEMS) light modulator configured to modulate light emitted by the backlight passing through the apertures to form an image on the display apparatus. The MEMS light modulator includes a shutter that has a light blocking portion having an aperture layer-facing surface and a front-facing surface and at least one depression formed in the light blocking portion. The width of the at least one depression accounts for at least 50% but less than 100% of a distance separating two edges of the shutter. | 12-05-2013 |
20130330995 | METHODS FOR MANUFACTURING COLD SEAL FLUID-FILLED DISPLAY APPARATUS - This methods and devices described herein relate to displays and methods of manufacturing cold seal fluid-filled displays, including MEMS. The fluid substantially surrounds the moving components of the MEMS display to reduce the effects of stiction and to improve the optical and electromechanical performance of the display. The invention relates to a method for sealing a MEMS display at a lower temperature such that a vapor bubble does not form forms only at temperatures about 15° C. to about 20° C. below the seal temperature. In some embodiments, the MEMS display apparatus includes a first substrate, a second substrate separated from the first substrate by a gap and supporting an array of light modulators, a fluid substantially filling the gap, a plurality of spacers within the gap, and a sealing material joining the first substrate to the second substrate. | 12-12-2013 |
20130335806 | MECHANICAL LIGHT MODULATORS WITH STRESSED BEAMS - The invention relates to a light modulator including a substrate having a surface and a modulation assembly coupled to the substrate that includes a modulation element and a first compliant beam. The first compliant beam includes a first segment that extend away from a first anchor and a second segment that extends back towards the first anchor. The length of the first segment is different than the length of the second segment. | 12-19-2013 |
20140085698 | MEMS ANCHORS - The invention relates to an improved apparatus and method for the design and manufacture of MEMS anchoring structures for light modulators in order to address the stresses of beams mounted on them. | 03-27-2014 |
20140145926 | DISPLAY APPARATUS WITH STICTION REDUCTION FEATURES - A display apparatus includes a plurality of electromechanical systems (EMS) devices disposed on a first surface defined by a face of a substrate. Each EMS device includes a component which is movable in a plane that is substantially parallel to the first surface. The apparatus also includes a second surface positioned proximate to the substrate such that the plurality of EMS devices are located between the first surface and the second surface. In addition, each EMS device includes at least one anti-stiction projection positioned between the movable component and the second surface. | 05-29-2014 |
20140168224 | DISPLAY DEVICE INCORPORATING MULTIPLE DIELECTRIC LAYERS - This disclosure provides systems, methods and apparatus for providing multiple dielectric coatings for a shutter assembly. The multiple dielectric coatings include an outer dielectric coating and one or more inner dielectric coatings. The outer dielectric coating has an electrical trap density that is lower than electrical trap densities of the one or more inner dielectric coatings. The lower electrical trap density reduces the amount of charge buildup over various surfaces of the shutter assembly. This reduction in charge buildup also reduces electrostatic forces that may cause incorrect operation of the shutter assembly. | 06-19-2014 |
20140175909 | Systems and Methods for Supporting a Movable Element of an Electromechanical Device - An electromechanical device includes a movable body that is movable along an axis of a direction of motion. The device also includes an actuator beam and a compliant support beam arranged to support the movable body. The compliant support beam includes a first end connected to an anchor and an actuating portion extending from the anchor and in a direction that is transverse to the axis of the direction of motion and away from the anchor. The actuating portion is also arranged adjacently and spaced apart from the actuator beam. The compliant support beam also includes a connector portion that is contiguous with the actuating portion and coupled to the movable body. The connector portion extends at least partially back toward the anchor while being arranged adjacently and spaced apart from the actuating portion. | 06-26-2014 |
20140184621 | DISPLAY APPARATUS INCLUDING DUAL ACTUATION AXIS ELECTROMECHANICAL SYSTEMS LIGHT MODULATORS - This disclosure provides systems, methods and apparatus for modulating light to form an image on a display. A light modulator in the display may include a substrate, a shutter, a first actuator and a second actuator. The shutter can be configured to selectively obstruct an optical path through the substrate. The first actuator can be configured to move the shutter in a first direction along a first axis in a plane substantially parallel to a plane defined by the substrate, thereby moving the shutter from a first state to a second state. The second actuator can be configured to move the shutter in a second direction along a second axis. The second axis can be substantially orthogonal to the first axis and also within a plane parallel to the substrate. In some implementations, moving the shutter along the second axis moves the shutter into a third state. | 07-03-2014 |
20140192061 | ELECTROMECHANICAL SYSTEMS HAVING SIDEWALL BEAMS - This disclosure provides systems, methods and apparatus for electromechanical systems having sidewalls beams. In one aspect, a device includes a substrate having a first electrode and a second electrode, and a movable shuttle monolithically integrated with the substrate, and having a first wall, a second wall, and a base. The first and second walls each have a first dimension at least four times larger than a second dimension. The first and second walls define substantially parallel vertical sides of the shuttle, and the base is positioned orthogonally to the first and second walls and forms a horizontal bottom of the shuttle, providing structural support to the first and second walls. The first wall and the first electrode define a first capacitor, and the second wall and the second electrode define a second capacitor. | 07-10-2014 |
20140204097 | ASYMMETRIC TRAVEL FOR MEMS LIGHT MODULATOR - Systems, apparatuses and methods are provided for increasing the aperture ratio of a display by increasing the total travel distance of respective light modulating bodies in a display while maintaining fast switching speeds. Increasing the total travel distance allows for a larger aperture ratio in a display, which provides greater power savings and increased display brightness. The total travel distance of a light modulating body includes the distance the body travels from an open position to a closed position, and vice-versa. In one example, the travel distance of a light modulating body (e.g., any of the light modulators as described above) is asymmetric: from a neutral position, the body travels a greater distance in a first direction than in a second direction. | 07-24-2014 |
20140268293 | Display Apparatus with Narrow Gap Electrostatic Actuators - This disclosure provides systems, methods and apparatus for incorporating tip-gap adjustment features (TGAF) in actuators of shutter assemblies. The TGAF are incorporated into a drive beam of the actuator during the formation of the shutter assembly over a mold. The TGAF are configured such that they develop a mechanical stress or stress gradient. When the shutter assembly is released from the mold, the stress or stress gradient in the TGAF bend the drive beam such that a tip-gap between the drive beam and a load beam of the actuator is reduced. The reduced tip-gap, in turn, reduces an actuation voltage needed to actuate the shutter assembly. | 09-18-2014 |
Patent application number | Description | Published |
20130208955 | CLOUD-BASED MEDICAL IMAGE PROCESSING SYSTEM WITH ACCESS CONTROL - According to one embodiment, a cloud server receives over a network a request for accessing three-dimensional (3D) medical image data from a first user, where the cloud server provides image processing services to a plurality of users using a plurality of image processing tools provided by the cloud server. The cloud server determines user privileges of the users for accessing the 3D medical image data, where the user privileges are related to the 3D medical image data. The 3D medical image data was captured by a medical imaging device and stored in a storage associated with the cloud server. The availability of the image processing tools is limited to the user to process the 3D medical image data based on the user privileges. | 08-15-2013 |
20130208966 | CLOUD-BASED MEDICAL IMAGE PROCESSING SYSTEM WITH ANONYMOUS DATA UPLOAD AND DOWNLOAD - According to one embodiment, a local device receives 3D medical image data captured by a medical imaging device. The 3D medical image is anonymized by removing certain metadata associated with the 3D medical image data based on an anonymization template. The local device automatically uploads the anonymized 3D medical image data to a cloud server over a network based on a set of one or more rules, using a network connection established via an internet port of the local device. The cloud server is configured to provide medical image processing services to a plurality of users using a plurality of image processing tools provided by the cloud server. | 08-15-2013 |
20140153808 | CLOUD-BASED MEDICAL IMAGE PROCESSING SYSTEM WITH TRACKING CAPABILITY - A cloud server receives a request for accessing medical image data from a client device, where the cloud server provides image processing services to users in image processing steps, resulting in image views. User privileges of a user are determined for accessing the medical image data. In response to receiving a command having a selection of an image view from the client device, the cloud server provides the medical image data based on the selected one or more image views. The user interactions of the user with the medical image data via the selected image views are tracked, including tracking how long in time the user has spent on a particular image view. The tracked user interactions are stored in a persistent storage, and an analysis is performed on the tracked user interactions stored in the persistent storage to determine an overall usage trend of the image views. | 06-05-2014 |
Patent application number | Description | Published |
20090163537 | Thienopyridinone Compounds and Methods of Treatment - The invention relates to 5-HT receptor agonists and partial agonists. Novel thienopyridinone compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, nonulcer dyspepsia, depression, anxiety, urinary incontinence, migraine, arrhythmia, atrial fibrillation, ischemic stroke, gastritis, gastric emptying disorders, feeding disorders, gastrointestinal disorders, constipation, erectile dysfunction, and respiratory depression. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included. | 06-25-2009 |
20110195953 | COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS - The invention generally relates to thienopyridinone 5-HT | 08-11-2011 |
20120115850 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT - The invention relates to 5-HT | 05-10-2012 |
Patent application number | Description | Published |
20100295225 | METHOD AND APPARATUS FOR FLUID PROCESSING A WORKPIECE - A method of fluid sealing a workpiece is provided. The method includes placing a workpiece on a ring, engaging at least one engagement feature of the ring with at least one retaining feature defined by the member and flexing the member to provide a force to the at least one engagement feature to cause the ring to form a barrier to fluid entry with the workpiece. | 11-25-2010 |
20100301564 | BALANCING PRESSURE TO IMPROVE A FLUID SEAL - A method of fluid sealing a workpiece is provided. The method includes providing a force to cause a ring to form a barrier to fluid entry with the workpiece and preventing fluid from crossing the barrier to fluid entry by forming a pressure differential across the barrier. | 12-02-2010 |
20110139627 | METHOD AND APPARATUS FOR FLUID PROCESSING A WORKPIECE - A method of fluid processing a semiconductor workpiece, including disposing a workpiece holder with a housing capable of containing a fluid, the workpiece holder retaining the workpiece, providing an agitation system connected to the housing and comprising a member disposed within the housing adjacent the workpiece holder, and agitating the fluid by moving the member substantially parallel to a surface of the workpiece with a non-uniform oscillatory motion, the non-uniform oscillatory motion being a series of substantially continuous geometrically asymmetric oscillations wherein each consecutive oscillation of the series is geometrically asymmetric having at least two substantially continuous opposing strokes wherein reversal positions of each substantially continuous stroke of the substantially continuous asymmetric oscillation are disposed asymmetrically with respect to a center point of each immediately preceding substantially continuous stroke of the oscillation. | 06-16-2011 |
20120103799 | METHOD AND APPARATUS FOR FLUID PROCESSING A WORKPIECE - A workpiece holder for fluid processing a workpiece including a transportable frame, a flexible member connected to the frame and defining at least one retaining feature, and a ring comprising at least one engagement feature engageable with the at least one retaining feature of the flexible member, wherein the flexible member is flexed to provide a force to the at least one engagement feature to cause the ring to form a barrier to fluid entry with the workpiece. | 05-03-2012 |
20130334036 | APPARATUS FOR FLUID PROCESSING A WORKPIECE - A method of fluid processing a semiconductor workpiece, including disposing a workpiece holder with a housing capable of containing a fluid, the workpiece holder retaining the workpiece, providing an agitation system connected to the housing and comprising a member disposed within the housing adjacent the workpiece holder, and agitating the fluid by moving the member substantially parallel to a surface of the workpiece with a non-uniform oscillatory motion, the non-uniform oscillatory motion being a series of substantially continuous geometrically asymmetric oscillations wherein each consecutive oscillation of the series is geometrically asymmetric having at least two substantially continuous opposing strokes wherein reversal positions of each substantially continuous stroke of the substantially continuous asymmetric oscillation are disposed asymmetrically with respect to a center point of each immediately preceding substantially continuous stroke of the oscillation. | 12-19-2013 |
Patent application number | Description | Published |
20120284084 | SCALABLE REGRESSION FOR RETAIL PANEL DATA - Systems, methods, and other embodiments associated with scalable regression for retail panel are described. In one embodiment, a method includes performing a regression that estimates elasticity of demand for a retail item, wherein the regression is performed on a transformation of a demand model that does not include variables associated with base demand or seasonality. In a subsequent processing step, the method includes estimating a base demand and seasonality for the retail item based, at least in part, on the estimated elasticity of demand. The method may be performed in a database that stores retail panel data for the retail item and other retail items. | 11-08-2012 |
20130185116 | AUTOMATIC DEMAND PARAMETER ESCALATION - A system provides automatic escalation of demand parameters to determine a reliable demand parameter for a level within a sales hierarchy. The system measures difference in demand parameters between a level of interest within the sales hierarchy and a plurality of other levels within the sales hierarchy. The system also compares the differences in demand parameters of the other levels. The system further determines an escalation path for a demand parameter based on the comparison. | 07-18-2013 |
20130185117 | AUTOMATIC DEMAND PARAMETER ESTIMATION - One embodiment is directed generally to a computer system, and in particular to a system for providing automatic estimating of demand parameters. According to certain embodiments, a computer readable medium has instructions stored thereon that, when executed by a processor, cause the processor to determine a reliable demand parameter for a level within a sales hierarchy. The instructions include estimating a demand parameter for a first pool. The estimating is based on blending and comparing with respect to an enlarged pool comprising the first pool as a subset of the enlarged pool to obtain an estimated demand parameter. | 07-18-2013 |
20130211877 | RETAIL PRODUCT PRICING MARKDOWN SYSTEM - A system that determines a pricing markdown schedule for a retail item at a store receives demand parameters of the retail item at the store and one or more constraints, and expresses a price curve and inventory curve as linear combinations of price and inventory coefficients for orthogonal polynomials. The system determines revenue in terms of values of the price and inventory coefficients, determines an initial guess of the price and inventory coefficients, and determines a gradient of the revenue. The system then maximizes the revenue based on the revenue, the initial guesses, the gradient, and the constraints, where the constraints are in terms of the price and inventory coefficients. Based on the maximized revenue, the system then generates the price markdown schedule. | 08-15-2013 |
20130211878 | ESTIMATING ELASTICITY AND INVENTORY EFFECT FOR RETAIL PRICING AND FORECASTING - A system that estimates elasticity and inventory effect for a product pricing or forecasting system receives a sales condition relationship for an item at a store, the relationship comprising an elasticity parameter, an inventory effect parameter and a sales constant. The system receives a demand model for sales of the item in terms of the elasticity parameter and the inventory effect parameter and a base demand for the item selling at the store. The system estimates the sales constant, the estimating comprising generating a theta parameter by taking logarithms of the sales condition relationship. The system uses linear regression to estimate a logarithm of the sales constant and a value of the theta parameter. The system determines a relationship between the elasticity parameter and the inventory effect parameter based on the value of the theta parameter. | 08-15-2013 |
20130346352 | CONSUMER DECISION TREE GENERATION SYSTEM - A system generates a consumer decision tree (“CDT”). The system receives customer purchasing data that includes transactions of a plurality of products each having at least one product attribute. For a product category, the system identifies a plurality of similar products from the purchasing data and one or more attributes corresponding to each similar product. The system assigns the product category as a current level of the CDT, and determines a most significant attribute of the plurality of attributes for the current level. The system forms a next level of the CDT by dividing the most significant attribute into a plurality of sub-sections, where each sub-section corresponds to an attribute value of the most significant attribute. The system then forms a next level of the CDT for each sub-section until a terminal node is identified. | 12-26-2013 |
20140358633 | DEMAND TRANSFERENCE FORECASTING SYSTEM - A demand transference forecast system receives for a category of merchandise de-promoted sales data for each of a plurality of stock keeping units (“SKUs”), similarities between each pair of SKUs in the category, and SKU-store ranging information. The system determines a sales indices of all SKUs in the category across the de-promoted sales data for the category. The system determines Total Assortment Effect (“TAE”) variable quantities for the SKUs across share intervals in the de-promoted sales data based on the sales indices and the similarities. The system then generates a single parameter based demand transference model based on the similarities, the sales indices, and ratios of the share intervals. | 12-04-2014 |
Patent application number | Description | Published |
20090124559 | Soft Protease Inhibitors and Pro-Soft Forms Thereof - The invention provides compounds and methods for inhibiting proteases. One aspect of the invention features pro-soft inhibitors which react with an activating protease to release an active inhibitor moiety in proximity to a target protease. In certain instances, compounds inhibit proteasomes and/or post-proline cleaving enzymes (PPCE), such as dipeptidyl peptidase IV. The compounds of the invention provide a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. | 05-14-2009 |
20110218142 | Inhibitors of Dipeptidylpeptidase IV - The present invention relates to inhibitors of post-proline cleaving enzymes, such as inhibitors of dipeptidyl peptidase IV, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. In particular, the inhibitors of the present invention are improved over those in the prior art by selection of particular classes of sidechains in the P1 and/or P2 position of the inhibitor that contain a carboxylic acid moiety. The compounds of the present invention can have a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. | 09-08-2011 |
20120077807 | NIACIN MIMETICS, AND METHODS OF USE THEREOF - Disclosed are 6-(morpholinoalkyl)-substituted pyridines, and pharmaceutically acceptable salts and prodrugs thereof, that are active against a range of mammalian therapeutic indications. | 03-29-2012 |
20120077808 | Niacin Mimetics, and Methods of Use Thereof - Disclosed are heterocyclylalkyl-substituted and heteroaralkyl-substituted pyridines, and pharmaceutically acceptable salts and prodrugs thereof, that are active against a range of mammalian therapeutic indications. | 03-29-2012 |
20120178677 | SOFT PROTEASE INHIBITORS, AND PRO-SOFT FORMS THEREOF - The invention provides compounds and methods for inhibiting proteases. One aspect of the invention features pro-soft inhibitors which react with an activating protease to release an active inhibitor moiety in proximity to a target protease. In certain instances, compounds inhibit proteasomes and/or post-proline cleaving enzymes (PPCE), such as dipeptidyl peptidase IV. The compounds of the invention provide a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. Another aspect of the invention provides for the use of the disclosed compounds for treating Type II diabetes, insulin resistance, glucose intolerance, hyperglycemia, hypoglycemia, hyperinsulinemia, obesity, hyperlipidemia, or hyperlipoproteinemia. | 07-12-2012 |
20130150292 | Soft Protease Inhibitors and Pro-Soft Forms Thereof - The invention provides compounds and methods for inhibiting proteases. One aspect of the invention features pro-soft inhibitors which react with an activating protease to release an active inhibitor moiety in proximity to a target protease. In certain instances, compounds inhibit proteasomes and/or post-proline cleaving enzymes (PPCE), such as dipeptidyl peptidase IV. The compounds of the invention provide a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. | 06-13-2013 |
20140018359 | Niacin Mimetics, and Methods of Use Thereof - Disclosed are 6-(morpholinoalkyl)-substituted pyridines, and pharmaceutically acceptable salts and prodrugs thereof, that are active against a range of mammalian therapeutic indications. | 01-16-2014 |
20140018545 | Inhibitors of Dipeptidylpeptidase IV - The present invention relates to inhibitors of post-proline cleaving enzymes, such as inhibitors of dipeptidyl peptidase IV, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. In particular, the inhibitors of the present invention are improved over those in the prior art by selection of particular classes of sidechains in the P1 and/or P2 position of the inhibitor that contain a carboxylic acid moiety. The compounds of the present invention can have a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. | 01-16-2014 |
20140128344 | Soft Protease Inhibitors and Pro-Soft Forms Thereof - The invention provides compounds and methods for inhibiting proteases. One aspect of the invention features pro-soft inhibitors which react with an activating protease to release an active inhibitor moiety in proximity to a target protease. In certain instances, compounds inhibit proteasomes and/or post-proline cleaving enzymes (PPCE), such as dipeptidyl peptidase IV. The compounds of the invention provide a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. | 05-08-2014 |
Patent application number | Description | Published |
20090269332 | Human diacylglycerol acyltransferase 2 (DGAT2) family members and uses therefor - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 10-29-2009 |
20090281191 | USE OF ORGANIC COMPOUNDS - Use of a ERRγ agonist Or pharmaceutically acceptable salt thereof, for the prevention, delay of progression or the treatment of diabetes, insulin resistance, metabolic disease/metabolic syndrome, dyslipdemia, obesity, overweight, Neurodegenerative diseases such as Parkinson's disease. Alzheimer's disease, Huntington's disease or improvement of exercise endurance capacity. | 11-12-2009 |
20100035339 | HUMAN DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2) FAMILY MEMBERS AND USES THEREFOR - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 02-11-2010 |
20120003233 | HUMAN DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2) FAMILY MEMBERS AND USES THEREFOR - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 01-05-2012 |
20120076729 | METHODS OF TREATING CANCERS - The present application describes methods for treating and/or preventing cancer or a cancer symptom, e.g., AMPK-related cancers, in a patient in need thereof comprising administering to the patient a therapeutically effective amount of an FGF, e.g., FGF21, or an FGF agonist, or a pharmaceutical composition comprising the same. | 03-29-2012 |
20120177661 | HUMAN DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2) FAMILY MEMBERS AND USES THEREFOR - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 07-12-2012 |
20130078239 | HUMAN DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2) FAMILY MEMBERS AND USES THEREFOR - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 03-28-2013 |
20140010799 | HUMAN DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2) FAMILY MEMBERS AND USES THEREFOR - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 01-09-2014 |