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Wraith
David Wraith, Bristol GB
| Patent application number | Description | Published |
|---|---|---|
| 20100129853 | DISEASE MARKERS - The present invention relates to biomarkers for autoimmune disease, and in particular to a method for determining a status of an autoimmune disease in a test subject, comprising measuring production of IL-5 and IL-13, as well as to associated uses and kits. | 05-27-2010 |
| 20100286054 | Composition - The present invention relates to a composition which comprises the following myelin basic protein peptides: MBP 30-44, MBP 83-99, MBP 131-145, and MBP 140-154. The composition may be used to treat a disease, in particular multiple sclerosis and/or optical neuritis and the invention also relates to such uses and methods. | 11-11-2010 |
| 20100323966 | FVIII Peptides and Their Use in Tolerising Haemophiliacs - The present invention provides a peptide comprising a core residue sequence derivable from human FVIII which peptide is capable of binding to an MHC class II molecule without further antigen processing. The present invention also relates to the use of such peptides for the prevention or suppression of inhibitor antibody formation in haemophilia A and/or acquired haemophilia. | 12-23-2010 |
David Cameron Wraith, Bristol GB
| Patent application number | Description | Published |
|---|---|---|
| 20080200368 | Peptide composition - There is provided a method for selecting a tolerogenic peptide by selecting a peptide which is capable of binding to an MHC class I or II molecule without further processing. There is also provided a peptide selected by such a method and its use in a pharmaceutical composition and a method to treat and/or prevent a disease. The present invention also relates to a composition which comprises the following myelin basic protein (MBP) peptides: MBP 30-44; MBP 83-99; MBP 131-145; and MBP 140-154. The composition may be used to treat a disease, in particular multiple sclerosis and/or optical neuritis and the invention also relates to such uses and methods. | 08-21-2008 |
Patrick Wraith, Bristol GB
| Patent application number | Description | Published |
|---|---|---|
| 20100248345 | PARTICLE FACILITATED TESTING - Magnetic particles are distributed across a fluid flow by applied magnetic field to interact with a test substance in fluid. Alternatively or additionally, particles, which may be magnetic, are combined with cells and energy, e.g. ultrasonic energy, is applied to cause the particles to create a lysate. Alternatively or additionally, the size of a quantity of magnetic particles is assessed by its impact on the tuning mechanism of a controlled oscillator that is affected by the particles. | 09-30-2010 |