Patent application number | Description | Published |
20080275220 | METHOD FOR STABILIZING A PROTEIN - The invention relates to a method for stabilizing an aqueous protein solution against exogenous stress and to the use of a container for stabilizing an aqueous protein solution. | 11-06-2008 |
20090048145 | In situ hardening paste, its manufacturing and use - An in-situ-hardening paste, containing an organic or inorganic filling material, a biodegradable polymer and a water soluble polymeric plasticizer was developed as a delivery system for an active agent with scaffold properties in the field of tissue regeneration. The hardened paste is sufficient mechanical stable to can be used as bone and cartilage replacement matrix. All components are full biocompatible, preferably bioresorbable and certified for parenteral application. The sustained release of peptides and proteins can be modulated by the composition and process design. The invention encompasses a pharmaceutical composition comprising the paste of the invention and relates to the use of said paste for the preparation of a pharmaceutical composition to be used for bone augmentation, for treating bone defects, for treating degenerative and traumatic disc disease, for treating bone dehiscence or to be used for sinus floor elevation. | 02-19-2009 |
20090209660 | BIOMATERIAL CONTAINING DEGRADATION STABILIZED POLYMER - The present invention relates to a polymer based material comprising a water binding agent, whereas the water binding agent is present in an amount sufficient to chemically and/or physically absorb and/or adsorb water to prevent degradation of the polymer. It also relates to a polymer based material which comprises a plasticizer or organic solvent as well as a multi-component material or composite including materials encompassing a second polymer and/or an active agent. Furthermore it relates to a method for manufacturing the polymer comprising material and use of the material for the preparation of a pharmaceutical composition to be used for treatment of bone, cartilage and/or periodontal defects. The invention also encompasses a kit using the polymeric material. Further, the present invention encompasses the use of a water binding agent for inhibiting water induced degradation of a polymer comprising material, for inducing blood clot stabilization in a polymer comprising material and for increasing storage stability in a polymer comprising material, wherein the water binding agent is not removed prior to application of the material. | 08-20-2009 |
20110247234 | DRYER WITH MONITORING DEVICE - The invention provides a monitoring device ( | 10-13-2011 |
20120004170 | Formulation Comprising Bioactive Agents And Method Of Using Same - Disclosed are methods of making bioactive BMP-2 microparticles and methods of using the microparticles. | 01-05-2012 |
20130129666 | BIOMATERIAL CONTAINING DEGRADATION STABILIZED POLYMER - The invention provides a polymer based material comprising a water binding agent present in an amount sufficient to chemically and/or physically absorb and/or adsorb water to prevent degradation of the polymer. The invention also provides a polymer based material comprising a plasticizer or organic solvent as well as a multi-component material or composite including materials encompassing a second polymer and/or an active agent. The invention further provides a pharmaceutical composition comprising the aforesaid polymer based material, which can be used for treatment of bone, cartilage and/or periodontal defects. | 05-23-2013 |
20150101208 | DRYER WITH MONITORING DEVICE - The invention provides a monitoring device ( | 04-16-2015 |
20150283094 | METHOD FOR PRODUCING A POLYGLYCEROL NANOGEL FOR THE ENCAPSULATION AND RELEASE OF BIOLOGICALLY ACTIVE SUBSTANCES - A method for producing a polyglycerol nanogel is disclosed, the method comprising the following steps: Mixing an aqueous solution of first polyglycerol macromonomers, which are modified with a first reactive group, with an aqueous solution of second polyglycerol macromonomers, which are modified with a second reactive group, wherein the first reactive group and the second reactive group can react with each other forming a chemical bond; transferring the mixture into an organic non-solvent; and precipitation of a polyglycerol nanogel consisting of first polyglycerol macromonomers and second polyglycerol macromonomers which are covalently bound to each other. According to an aspect of the invention, the method is characterized in that the organic non-solvent is miscible with water and in that the method is carried out without adding surface-active substances. | 10-08-2015 |