Wistuba
Dirk Wistuba, Mulheim An Der Ruhr DE
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20110052397 | Stator Blade for a Turbomachine which is Exposable to Axial Throughflow, and also Stator Blade Arrangement for It - A stator blade and a stator blade arrangement for a turbomachine which is exposable to axial throughflow is provided. Each stator blade is retained via a fixed clamping in a circumferential groove. For the fixed clamping, provision is made on one side of the blade root for a shaped piece with a threaded hole into which a tensioning screw, which is supported on the bottom of the circumferential groove, may be screwed. | 03-03-2011 |
20110171031 | Turbomachine Rotor Comprising a Pretensioning Device for Pretensioning a Guide Vane - A turbomachine rotor, a rotor blade and a method for assembling a turbomachine rotor are provided. The turbomachine rotor includes a rotor blade with a blade root, a wheel disk with a groove in which the blade root engages such that the rotor blade is maintained in the groove in a positive fit in a radial direction. Further, a pretensioning device is provided, which is supported on the wheel disk as well as on the blade root and which exerts a pretensioning force on the blade root in the radial direction. The pretensioning device is designed such that the pretensioning force can be adjusted when assembling the turbomachine rotor. | 07-14-2011 |
20140234111 | BLADE ARRANGEMENT - A blade arrangement is provided having a blade carrier and a retaining groove arranged therein, which retaining groove has projections extending along side walls thereof forming undercuts and into which a number of blades are inserted forming a blade ring of a turbomachine. Each blade has a blade root which engages into the undercuts, and each blade is pressed against the projections by an element arranged between a blade root underside and a groove base of the retaining groove. It is further provided that each element is of plate-like form and has, in the projection of the blade airfoil in the direction of the groove base, at least one bead, arranged beneath the blade airfoil, for imparting a pressing action, and in the longitudinal direction of the retaining groove, only part of the blade root which the element presses against is covered. | 08-21-2014 |
Ignacio Wistuba, Houston, TX US
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20150017210 | Gene Signature Predicts Adenocarcinoma Prognosis and Therapeutic Response - The present invention is drawn to methods of predicting prognosis of, and therapeutic response in, carcinoma of the lung. | 01-15-2015 |
Ignacio I. Wistuba, Houston, TX US
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20120244209 | TUSC2 THERAPIES - A method for predicting a subject's response to a TUSC2 therapy is provided. In particular, a subject's response is predicted based on the proportion of cancers cells that are apoptotic. Also provided is a method of treating a subject previously predicted to have a favorable response with a TUSC2 therapy. Methods for treating cancer by administration of a TUSC2 therapeutic in conjunction with an EGFR inhibitor and/or a protein kinase inhibitor are also disclosed. Kits and reagents for use in TUSC2 therapy are provided. | 09-27-2012 |
20130230511 | BIOMARKERS FOR RESPONSE TO TYROSINE KINASE PATHWAY INHIBITORS IN CANCER - Copy number gains detected in tumors and associated with drug sensitivity and resistance in vivo and in vitro can be used as biomarkers to select, predict and monitor drug treatment outcomes in cancer patients treated with tyrosine kinase inhibitors. Methods to identify patients with NSCLC or other malignancies who are more likely to benefit from tyrosine kinase inhibitors such as VEGF or VEGFR inhibitors when used either as monotherapy or in combination with other therapies such as chemotherapy or EGFR inhibitors, and who are in the advanced stages of disease and/or who have undergone adjuvant therapy are also provided herein. | 09-05-2013 |
20140377339 | TUSC2 THERAPIES - A method for predicting a subject's response to a TUSC2 therapy is provided. In particular, a subject's response is predicted based on the proportion of cancers cells that are apoptotic. Also provided is a method of treating a subject previously predicted to have a favorable response with a TUSC2 therapy. Methods for treating cancer by administration of a TUSC2 therapeutic in conjunction with an EGFR inhibitor and/or a protein kinase inhibitor are also disclosed. Kits and reagents for use in TUSC2 therapy are provided. | 12-25-2014 |
Joachim Wistuba, Bielefield DE
Michael Wistuba, Wien AT
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20110041733 | METHOD FOR PRODUCING AN AGGREGATE FOR PRODUCING BUILDING MATERIALS - The invention relates to a method for producing an aggregate for the production of building materials, wherein a starting material containing at least one fibre-containing waste fraction has had heavy materials removed and been comminuted in order to obtain a substantially free-flowing aggregate. Improved product properties can be achieved in such a way that the fibre content is set between 3% and 45%, preferably between 5% and 25%, and more preferably between 7% and 12%, and a mass fraction of between 2% and 25%, preferably between 2% and 10%, and more preferably between 3% and 8%, of a fine-grain inorganic additive is set. The invention further relates to an aggregate produced according to this method, and to asphalt or concrete. | 02-24-2011 |
Troy Wistuba, Ballwin, MO US
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20150209416 | COMPOSITION AND METHOD FOR CO-ADMINISTRATION WITH A GROWTH PROMOTANT - Embodiments of a composition comprising silica, mineral clay, mannans, or any combination thereof are disclosed. The composition may further comprise glucan. The composition is administered to an animal that will be administered, or has been administered, a growth promotant. The growth promotant may be a β-agonist, antibiotic, steroid or hormone. The composition is fed to the animal for a period of time before administration of the growth promotant, during administration of the growth promotant, and/or after administration of the growth promotant. Administration of the composition to the animal ameliorates, or prevents development of, at least one deleterious symptom or sign, such as a deleterious symptom or sign potentially associated with administration of the growth promotant. Embodiments of a composition comprising (i) a growth promotant and (ii) glucan, silica, mineral clay, mannans, or any combination thereof also are disclosed. | 07-30-2015 |