Patent application number | Description | Published |
20080253985 | Compositions for Lowering Serum Cholesterol and/or Triglycerides - The invention provides methods and compositions for treating hyperlipidemia and disorders associated with hyperlipidemia in a mammal. Compositions useful in the practice of the invention include a microsomal triglyceride transport protein inhibitor (“MTPI”) and at least two other cholesterol lowering drugs selected from the group consisting of a cholesterol absorption inhibitor (“CAI”), a HMG-CoA reductase inhibitor, a bile acid sequestrant, a fibric acid derivative, niacin, and squalene synthetase inhibitor. | 10-16-2008 |
20090054393 | METHODS FOR TREATING DISORDERS ASSOCIATED WITH HYPERLIPIDEMIA IN A MAMMAL - The invention is directed to methods for treating hyperlipidemia in a mammal. The methods involve combination therapies using a microsomal triglyceride transfer protein (MTP) inhibitor (for example, BMS-201038 and implitade) and a cholesterol absorption inhibitor (CAI) (for example, ezetimibe). Co-administration of the MTP inhibitor with the CAI produces a therapeutic benefit, for example, a reduction in the concentration of cholesterol and/or triglycerides in the blood stream, but with fewer or reduced side effects than when higher dosages of the MTP inhibitor are used during monotherapy to provide the same or similar therapeutic benefit. | 02-26-2009 |
20100273829 | Methods for Treating Disorders Associated with Hyperlipidemia in a Mammal - The invention is directed to methods for treating disorders associated with hyperlipidemia in a mammal. The methods involve combination therapies using a microsomal triglyceride transfer protein (MTP) inhibitor (for example, BMS-201038 and implitapide) and a fibrate (for example, fenofibrate). Co-administration of the MTP inhibitor with the fibrate produces a therapeutic benefit, for example, a reduction in the concentration of cholesterol and/or triglycerides in the blood stream, but with fewer or reduced side effects than when higher dosages of the MTP inhibitor are used during monotherapy to provide the same or similar therapeutic benefit. | 10-28-2010 |
20110288064 | METHODS FOR TREATING DISORDERS ASSOCIATED WITH HYPERLIPIDEMIA IN A MAMMAL - The invention is directed to methods for treating hyperlipidemia in a mammal. The methods involve combination therapies using a microsomal triglyceride transfer protein (MTP) inhibitor (for example, BMS-201038 and implitade) and a cholesterol absorption inhibitor (CAI) (for example, ezetimibe). Co-administration of the MTP inhibitor with the CAI produces a therapeutic benefit, for example, a reduction in the concentration of cholesterol and/or triglycerides in the blood stream, but with fewer or reduced side effects than when higher dosages of the MTP inhibitor are used during monotherapy to provide the same or similar therapeutic benefit. | 11-24-2011 |
20110288110 | METHODS FOR TREATING DISORDERS ASSOCIATED WITH HYPERLIPIDEMIA IN A MAMMAL - The invention is directed to methods for treating hyperlipidemia in a mammal. The methods involve combination therapies using a microsomal triglyceride transfer protein (MTP) inhibitor (for example, BMS-201038 and implitapide) and a HMG-CoA reductase inhibitor (for example simvastatin or atorvastatin). Co-administration of the MTP inhibitor with the HMG-CoA reductase inhibitor produces a therapeutic benefit, for example, a reduction in the concentration of cholesterol and/or triglycerides in the blood stream, but with fewer or reduced side effects than when higher dosages of the MTP inhibitor are used during monotherapy to provide the same or similar therapeutic benefit. | 11-24-2011 |
20120071458 | METHODS FOR TREATING OBESITY - The invention is directed to methods for treating and/or controlling obesity in a patient. The methods involve combination therapies using a microsomal triglyceride transfer protein (MTP) inhibitor (for example, AEGR-733 and implitapide) and a cholesterol absorption inhibitor (CAI) (for example, ezetimibe). | 03-22-2012 |
20130102635 | Methods for Treating Disorders Associated with Hyperlipidemia in a Mammal - The invention is directed to methods for treating hyperlipidemia in a mammal. The methods involve combination therapies using a microsomal triglyceride transfer protein (MTP) inhibitor (for example, BMS-201038 and implitapide) and a HMG-CoA reductase inhibitor (for example simvastatin or atorvastatin). Co-administration of the MTP inhibitor with the HMG-CoA reductase inhibitor produces a therapeutic benefit, for example, a reduction in the concentration of cholesterol and/or triglycerides in the blood stream, but with fewer or reduced side effects than when higher dosages of the MTP inhibitor are used during monotherapy to provide the same or similar therapeutic benefit. | 04-25-2013 |
Patent application number | Description | Published |
20130095179 | METHODS AND COMPOSITIONS FOR TREATING, REVERSING, INHIBITING OR PREVENTING RESISTANCE TO ANTIPLATELET THERAPY - Methods of identifying subjects who are resistant to antiplatelet therapy, such as therapy with clopidogrel, are presented. The methods comprise determining is whether the subject is an efficient converter of medium chain polyunsaturated fatty acids to long-chain polyunsaturated fatty acids. Also provided are methods of treating resistance to antiplatelet therapy in subjects who are efficient converters of medium chain polyunsaturated fatty acids to long-chain polyunsaturated fatty acids, comprising adjunctively administering to the subject an effective amount of a composition comprising omega-3 long chain polyunsaturated fatty acids. Improved methods of antiplatelet therapy are provided, wherein the improvement comprises adjunctive administration of a composition comprising omega-3 long chain polyunsaturated fatty acids in free acid form. Dosage forms comprising at least one antiplatelet agent and compositions comprising omega-3 long chain polyunsaturated fatty acids, including compositions comprising omega-3 long chain polyunsaturated fatty acids in free acid form, are provided. | 04-18-2013 |
20130177643 | DPA-ENRICHED COMPOSITIONS OF OMEGA-3 POLYUNSATURATED FATTY ACIDS IN FREE ACID FORM - DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented. | 07-11-2013 |
20130209556 | DPA-ENRICHED COMPOSITIONS OF OMEGA-3 POLYUNSATURATED FATTY ACIDS IN FREE ACID FORM - DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented. | 08-15-2013 |
Patent application number | Description | Published |
20120206557 | COMMUNICATIONS ADAPTABLE TO MOBILE DEVICES - A communication system is provided that is preferably a peer-to-peer (p2p) system. One or both of audio and video can be transferred among user terminals in the p2p system. The user terminals can include at least one master terminal, which could be an unhosted master terminal that does not communicate its own audio and/or video. In one embodiment, a first master terminal is included that controls video and/or audio, transfers and an unhosted second master terminal is provided that communicates with at least two user terminals to provide desired connectivity involving such user terminals. In another embodiment, an unhosted master terminal is provided when the user terminals include mobile terminals in order to avoid power usage by mobile terminals. This communication system can be utilized with online game playing in which a game server is included, as well as having other communication applications. | 08-16-2012 |
20120209933 | Peer-To-Peer Communications - A peer-to-peer (p2p) communication system is provided. One or both of audio and video can be transferred among a number of user terminals in the p2p system. The user terminals include at least one master terminal. The master terminal is identified, based on a determined topology, using obtained information provided in a data parameters table. Each user terminal includes a control for processing video and/or audio that is sent and/or received by the user terminal. The master terminal control can process the same video and/or audio and generate different video and/or audio data to be provided to different user terminals. Such different video data is a function of the communication paths between the master terminal and the different user terminals. Such different audio data can be a function of virtual relative positions associated with the user terminals. Audio volumes can also be separately controlled by each user terminal. Video and/or audio can be transferred in an aggregate manner, such as when the master terminal sends audio originating from a number of user terminals to another user terminal. This p2p system can be utilized with online game playing. | 08-16-2012 |
20140024430 | Gaming Machines Players' Communications - Communication networks are established involving gaming machines, preferably slot machines. Each gaming machine has a card reader for obtaining player identity-related information using player identification cards and also has a number of communication related devices including a video screen. In forming a network, identity-related information from two or more player identification cards are accessed using the card reader of one of the machines. A menu and a number of screens are displayable using the machine's video screen to facilitate the establishment of communication networks, as well as control elements being displayed for use in controlling communications using the communication-related devices. | 01-23-2014 |
20140347437 | Communications Adaptable to Mobile Devices - A communication system is provided that is preferably a peer-to-peer (p2p) system. One or both of audio and video can be transferred among a number of user terminals in the p2p system. The user terminals can include at least one master terminal, which could be an unhosted master terminal that does not communicate its own audio and/or video. In one embodiment, a first master terminal is included that controls video or audio, or both, transfers among user terminals and an unhosted second master terminal is provided that communicates with at least two user terminals to provide desired connectivity involving such user terminals in order to ensure proper audio and/or video communications between or among them. In another embodiment, an unhosted master terminal is provided with the communication system when the user terminals include mobile terminals in order to avoid power usage by mobile terminals. This communication system can be utilized with online game playing in which a game server is included, as well as having other communication applications. | 11-27-2014 |
Patent application number | Description | Published |
20080224707 | Array Antenna for Measurement-While-Drilling - An electromagnetic antenna for Measurement-While-Drilling (MWD) applications is disclosed. The antenna can include several array elements that can act alone or together in various measurement modes. The antenna elements can be disposed in tool body recesses to be protected from damage. The antenna elements can include a ferrite plate crossed or looped by independent current carrying conductors in two or more directions forming a bi-directional or crossed magnetic dipole. Although disclosed as a MWD system conveyed by a drill string, basic concepts of the system are applicable to other types of borehole conveyance. | 09-18-2008 |
20110024190 | METHOD AND APPARATUS FOR TRANSMITTING SENSOR RESPONSE DATA AND POWER THROUGH A MUD MOTOR - Apparatus and methods for establishing electrical communication between an instrument subsection disposed below a mud motor and an electronics sonde disposed above the mud motor in a drill string conveyed borehole logging system. Electrical communication is established via at least one conductor disposed within the mud motor and connecting the instrument sub section to a link disposed between the mud motor and the electronics sonde. The link can be embodied as a current coupling link, a magnetic coupling ling, an electromagnetic telemetry ling and a direct electrical contact link. Two way data transfer is established in all link embodiments. Power transfer is also established in all but the electromagnetic telemetry link. | 02-03-2011 |
20110084697 | STEERABLE MAGNETIC DIPOLE ANTENNA FOR MEASUREMENT WHILE DRILLING APPLICATIONS - A steerable, magnetic dipole antenna for Measurement-While-Drilling (MWD) or Logging-While-Drilling (LWD) applications. The antenna elements use a hole arrangement in addition to grooves in a steel tool body, which is typically a drill collar. This antenna embodiment is extremely robust, meaning that does not significantly reduce the structural integrity of the tool body in which it is disposed. The antenna embodiment is also relatively wear resistant. The resultant magnetic dipole generated by this antenna is also electrically steerable in inclination angle from a common origin. A variable dipole moment inclination angle combined with independently measured tool rotation orientation during normal drilling allows the antenna to generate a magnetic dipole moment that may be directed at any three dimensional angle and from a common origin point at the centroid of the antenna. | 04-14-2011 |
20110084698 | STEERABLE MAGNETIC DIPOLE ANTENNA FOR MEASUREMENT WHILE DRILLING APPLICATIONS - A steerable, magnetic dipole antenna for Measurement-While-Drilling (MWD) or Logging-While-Drilling (LWD) applications. The antenna elements use a hole arrangement in addition to grooves in a steel tool body, which is typically a drill collar. This antenna embodiment is extremely robust, meaning that does not significantly reduce the structural integrity of the tool body in which it is disposed. The antenna embodiment is also relatively wear resistant. The resultant magnetic dipole generated by this antenna is also electrically steerable in inclination angle from a common origin. A variable dipole moment inclination angle combined with independently measured tool rotation orientation during normal drilling allows the antenna to generate a magnetic dipole moment that may be directed at any three dimensional angle and from a common origin point at the centroid of the antenna. The antenna can also be embodied to be more sensitive to resitivity in a particular azimuthal direction. | 04-14-2011 |
20110084699 | STEERABLE MAGNETIC DIPOLE ANTENNA FOR MEASUREMENT-WHILE-DRILLING APPLICATIONS - A steerable or non-steerable, magnetic dipole antenna for Measurement-While-Drilling (MWD) or Logging-While-Drilling (LWD) applications. The antenna elements use a hole arrangement in addition to grooves in a steel tool body, which is typically a drill collar. This antenna embodiment is extremely robust, meaning that does not significantly reduce the structural integrity of the tool body in which it is disposed. The antenna embodiment is also relatively wear resistant. The resultant magnetic dipole generated by this antenna is also electrically steerable in inclination angle from a common origin. A variable dipole moment inclination angle combined with independently measured tool rotation orientation during normal drilling allows the antenna to generate a magnetic dipole moment that may be directed at any three dimensional angle and from a common origin point at the centroid of the antenna. The antenna can also be embodied to be more sensitive to resistivity in a particular azimuthal direction. | 04-14-2011 |
20110187373 | STEERABLE MAGNETIC DIPOLE ANTENNA FOR MEASUREMENT-WHILE-DRILLING APPLICATIONS - A steerable or non-steerable, magnetic dipole antenna for Measurement-While-Drilling (MWD) or Logging-While-Drilling (LWD) applications. The antenna elements use a hole arrangement in addition to grooves in a steel tool body, which is typically a drill collar. This antenna embodiment is extremely robust, meaning that does not significantly reduce the structural integrity of the tool body in which it is disposed. The antenna embodiment is also relatively wear resistant. The resultant magnetic dipole generated by this antenna is also electrically steerable in inclination angle from a common origin. A variable dipole moment inclination angle combined with independently measured tool rotation orientation during normal drilling allows the antenna to generate a magnetic dipole moment that may be directed at any three dimensional angle and from a common origin point at the centroid of the antenna. The antenna can also be embodied to be more sensitive to resitivity in a particular azimuthal direction. | 08-04-2011 |
20110278066 | METHOD AND APPARATUS FOR TRANSMITTING SENSOR RESPONSE DATA AND POWER THROUGH A MUD MOTOR - Apparatus and methods for establishing electrical communication between an instrument subsection disposed below a mud motor and an electronics sonde disposed above the mud motor in a drill string conveyed borehole logging system. Electrical communication is established via at least one conductor disposed within the mud motor and connecting the instrument sub section to a link disposed between the mud motor and the electronics sonde. The link can be embodied as a current coupling link, a magnetic coupling ling, an electromagnetic telemetry ling and a direct electrical contact link. Two way data transfer is established in all link embodiments. Power transfer is also established in all but the electromagnetic telemetry link. | 11-17-2011 |
20120194195 | Magnetic Ranging Method and Apparatus - A method and system is provided for minimizing delays in a magnetic ranging method. Delays are minimized by establishing synchronicity between triggering of a three-axis magnetometer and energisation of a solenoid assembly deployed in the borehole being drilled and the first borehole, respectively. Synchronicity enables measuring various components of the alternating magnetic field created by energisation of the solenoid assembly by the magnetometer, the moment the solenoid assembly is energised. The recorded components are used for computation of steering data for drilling the second borehole relative to the first borehole. The steering data can be determined at the surface or downhole. | 08-02-2012 |
20140345947 | Method for Minimizing Delays While Drilling Using a Magnetic Ranging Apparatus - A method and system is provided for minimizing delays in a magnetic ranging method. Delays are minimized by establishing synchronicity between triggering of a three-axis magnetometer and energisation of a solenoid assembly deployed in the borehole being drilled and the first borehole, respectively. Synchronicity enables measuring various components of the alternating magnetic field created by energisation of the solenoid assembly by the magnetometer, the moment the solenoid assembly is energised. The recorded components are used for computation of steering data for drilling the second borehole relative to the first borehole. The steering data can be determined at the surface or downhole. | 11-27-2014 |