Wimmer, US
Chris James Wimmer, Raleigh, NC US
Patent application number | Description | Published |
---|---|---|
20130337565 | Method and Apparatus for Patterning Cells - The present invention is directed to tissue engineering and, more particularly, to devices and methods that are used to pattern or deposit cells to simulate a tissue type in two dimensions or in three dimensions or a cell migration device, a materials testing device for cell proliferation, migration or cell seeder for the Bioflex® flexible bottom culture plates or comparable culture plates. The present invention operates by providing negative pressure to create multiple troughs or indentations for cells to attach and grow on or in the Bioflex® flexible bottom culture plates. The present invention is also directed to a device and method for simulating a tissue wound using the above devices. | 12-19-2013 |
Christian Wimmer, Foster City, CA US
Patent application number | Description | Published |
---|---|---|
20140189661 | SELF-OPTIMIZING INTERPRETER AND SNAPSHOT COMPILATION - A method for a compiler includes receiving, by the compiler and from an interpreter, a representation of a code section having a control path that changes the representation. The representation has profiling data, and the profiling data has a threshold. The method further includes performing, by the compiler and based on the threshold, a partial evaluation of the interpreter executing the representation, compiling, by the compiler, a machine code of the representation, with the control path replaced by a deoptimization point during the compilation of the machine code, triggering the deoptimization point during execution of the machine code, and returning execution to the interpreter based on the triggering. | 07-03-2014 |
Christopher L. Wimmer, Issaquah, WA US
Patent application number | Description | Published |
---|---|---|
20150310472 | MANAGEMENT OF ON-DEMAND CONTENT - Various embodiments relating to managing content sharing and consumption are disclosed. In one embodiment, a consumer may be issued a lifetime license for a content item. In response to issuing the lifetime license to the consumer one or more share credits may be issued to the consumer. A request to consume a requested content item on a temporary basis may be received from the consumer. A temporary digital authorization usable by the consumer to consume the requested content item on a temporary basis may be issued to the consumer in exchange for a share credit. | 10-29-2015 |
Eckard Wimmer, E. Setauket, NY US
Patent application number | Description | Published |
---|---|---|
20090246216 | NOVEL ATTENUATED POLIOVIRUS - A novel and stable attenuated poliovirus, which replicates in neuroblastoma cells, is produced by engineering an indigenous replication element (cre), into the 5′ non-translated genomic region and inactivating the native cre element located in the coding region of 2C (mono-crePV). The stably attenuated poliovirus replicates in a neuroblastoma model (Neuro-2a | 10-01-2009 |
20120064113 | Novel Attenuated Poliovirus - A novel and stable attenuated poliovirus, which replicates in neuroblastoma cells, is produced by engineering an indigenous replication element (cre), into the 5′ non-translated genomic region and inactivating the native cre element located in the coding region of 2C (mono-crePV). The stably attenuated poliovirus replicates in a neuroblastoma model (Neuro-2a | 03-15-2012 |
20150368622 | ATTENUATION OF HUMAN RESPIRATORY SYNCYTIAL VIRUS BY GENOME SCALE CODON-PAIR DEOPTIMIZATION - Described herein are RSV polynucleotide sequences that make use of multiple codons that are containing silent nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce a numerous synonymous codons into the genome. Due to the large number of defects involved, the attenuated viruses disclosed herein provide a means of producing attenuated, live vaccines against RSV. | 12-24-2015 |
Eckard Wimmer, Stony Brook, NY US
Patent application number | Description | Published |
---|---|---|
20150368622 | ATTENUATION OF HUMAN RESPIRATORY SYNCYTIAL VIRUS BY GENOME SCALE CODON-PAIR DEOPTIMIZATION - Described herein are RSV polynucleotide sequences that make use of multiple codons that are containing silent nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce a numerous synonymous codons into the genome. Due to the large number of defects involved, the attenuated viruses disclosed herein provide a means of producing attenuated, live vaccines against RSV. | 12-24-2015 |
Eckard Wimmer, East Setauket, NY US
Patent application number | Description | Published |
---|---|---|
20100209454 | ATTENUATED VIRUSES USEFUL FOR VACCINES - This invention provides an attenuated virus which comprises a modified viral genome containing nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce synonymous deoptimized codons into the genome. The instant attenuated virus may be used in a vaccine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated virus. Further, this invention further provides a method for preventing a subject from becoming afflicted with a virus-associated disease comprising administering to the subject a prophylactically effective dose of a vaccine composition comprising the instant attenuated virus. | 08-19-2010 |
20120269849 | ATTENUATED INFLUENZA VIRUSES AND VACCINES - The present provides attenuated influenza viruses comprising a modified viral genome containing a plurality of nucleotide substitutions. The nucleotide substitutions result in the rearrangement of preexisting codons of one or more protein encoding sequences and changes in codon pair bias. Substitutions of non-synonymous and synonymous codons may also be included. The attenuated influenza viruses enable production of improved vaccines and are used to elicit protective immune responses. | 10-25-2012 |
20140356962 | NOVEL ATTENUATED POLIOVIRUS: PV-1 MONO-CRE-X - A novel and stable attenuated poliovirus is produced by engineering an indigenous replication element (cre), into the 5′ non-translated genomic region (with inactivation of the native ere element located in the coding region of 2C (mono-crePV), and replacing the nucleic acid sequence of all or part of the capsid coding region (PI) with a substitute PI coding region having reduced codon pair bias. The stably attenuated poliovirus is effective for vaccines and immunization. | 12-04-2014 |
20160024477 | ATTENUATED INFLUENZA VIRUSES AND VACCINES - This invention provides highly attenuated influenza viruses and vaccines. The attenuated viruses and vaccines proliferate well and have high safety factors. The attenuated viruses providing protective immunity from challenge by virus of the same subtype, as well as cross protection against heterologous viruses. | 01-28-2016 |
Edward Wimmer, Lakeside Park, KY US
Patent application number | Description | Published |
---|---|---|
20150350860 | METHOD AND APPARATUS FOR EMERGENCY CONTACT MANAGEMENT - A system and method for tracking a person is presented. A system includes an electronic device to be carried by a person that is used to notify one or more remote users that the person is to begin a journey from a starting point to a remote point. The electronic device can detect that the person has not moved for a predetermined time period a predetermined distance. When this happens, the electronic device sends non-movement messages to the one or more remote users informing them that the person has not move for a predetermined time period a predetermined distance. The electronic device provides a warning message that the non-movement messages will be sent and sends them if there was no response to the warning message. | 12-03-2015 |
Frank Lee Wimmer, Raleigh, NC US
Patent application number | Description | Published |
---|---|---|
20120233573 | TECHNIQUES TO PRESENT HIERARCHICAL INFORMATION USING ORTHOGRAPHIC PROJECTIONS - Techniques to present hierarchical information as orthographic projections are described. An apparatus may comprise an orthographic projection application arranged to manage a three dimensional orthographic projection of hierarchical information. The orthographic projection application may comprise a hierarchical information component operative to receive hierarchical information representing multiple nodes at different hierarchical levels, and parse the hierarchical information into a tree data structure, an orthographic generator component operative to generate a graphical tile for each node, arrange graphical tiles for each hierarchical level into graphical layers, and arrange the graphical layers in a vertical stack, and an orthographic presentation component operative to present a three dimensional orthographic projection of the hierarchical information with the stack of graphical layers each having multiple graphical tiles. Other embodiments are described and claimed. | 09-13-2012 |
20140267424 | PROPORTIONAL HIGHLIGHTING OF DATA - A method of proportional highlighting of data is provided. A graph presented on a display includes a first axis, a second axis, and a first value marker that indicates a value determined from data selected for presentation. The first axis includes a minimum value and a maximum value. The second axis includes a plurality of category values. An indicator identifying a subset of the data is received. A proportional value is determined for the first value marker based on the received indicator. A second value marker indicating the proportional value is presented on the graph overlaid on the first value marker when the determined proportional value is between the minimum value and the maximum value. A scale adjustment marker is presented on the graph without adjusting the first axis when the determined proportional value is not between the minimum value and the maximum value. | 09-18-2014 |
Guenther Wimmer, West Linn, OR US
Patent application number | Description | Published |
---|---|---|
20140054054 | BATTERY OPERATED TOOL - Embodiments provide methods, apparatuses, and systems for battery operated tools, such as chainsaws, are provided. In accordance with embodiments herein, a chainsaw may include various components, such as a control board having a controller, a battery terminal block, a motor, a brake switch, a trigger switch, and/or other components. In various embodiments, components of the battery operated tool are provided that improve the capabilities and/or operation of the tool. | 02-27-2014 |
Karl Wimmer, Austin, TX US
Patent application number | Description | Published |
---|---|---|
20160132628 | METHOD OF DESIGNING AN INTEGRATED CIRCUIT AND COMPUTER PROGRAM PRODUCT - A method of designing an integrated circuit is described. The integrated circuit comprises a plurality of circuit components, including one or more functional components and one or more tile shapes. A pcell instance may be defined to specify a functional component along with one or more tile shapes. The tile shapes are thus associated with the functional component. A netlist may be arranged to specify interconnections between the functional components of the integrated circuit as well as electrical interactions between the tile shapes and functional components. | 05-12-2016 |
Markus Wimmer, Chicago, IL US
Patent application number | Description | Published |
---|---|---|
20100010630 | PLASTIC IMPLANT IMPREGNATED WITH A DEGRADATION PROTECTOR - A plastic implant device for a mammal that contains a rare earth metal compound tracer and a method for detecting degradation such as wear of the implanted device are disclosed. The tracer can also be present with a separate antioxidant or the tracer compound can be can be the salt of a C | 01-14-2010 |
20100174372 | PLASTIC IMPLANT IMPREGNATED WITH A DEGRADATION PROTECTOR - A plastic implant device for a mammal that contains a rare earth metal compound tracer and a method for detecting degradation such as wear of the implanted device are disclosed. The tracer can also be present with a separate antioxidant or the tracer compound can be can be the salt of a C | 07-08-2010 |
Megan Elizabeth Wimmer, Milwaukee, WI US
Patent application number | Description | Published |
---|---|---|
20140098931 | DUAL DISPLAY CT SCANNER USER INTERFACE - A user interface for a CT imaging system is disclosed. The user interface includes a first display configured to enable an operator to perform set-up and scanning tasks associated with performing a CT exam on one or more patients, with the set-up and scanning tasks including acquiring and verifying scan image data. The user interface also includes a second display configured to enable the operator to perform image post-processing tasks associated with the CT exams on the one or more patients, with the image post-processing tasks including performing image reconstructions and reformats. Each of the first display and the second display are operable independent from one another to provide for parallel workflows between the first display and second display and between the patient set-up and scanning tasks and the post-processing tasks. | 04-10-2014 |
20140098932 | DUAL DISPLAY CT SCANNER USER INTERFACE - A CT user interface includes first and second displays that selectively display distinct display zones thereon. The first display includes a zone enabling the operator to create a record for each of a plurality of patients and an exam set-up and a protocol selection zone enabling the operator to select a scan protocol for performing a CT scan on a selected patient. A task list zone on the first display displays all steps and sub-steps of a CT scan for a selected patient based on the selected scan protocol, and a settings zone and a scanning zone on the first display displays and enables operator selection of a plurality of scan parameters related to the selected scan protocol. Any general user interface elements not needed for the selected scan protocol are not displayed on the first and second displays, so as to simplify the user interface for the operator. | 04-10-2014 |
20140098933 | DUAL DISPLAY CT SCANNER USER INTERFACE - A CT user interface includes first and second displays that enable an operator to perform set-up and scanning tasks associated with performing CT scans and enable the operator to perform image post-processing tasks associated with the CT scans. A plurality of distinct display zones are selectively displayed on the first and second displays, with the first display displaying a zone enabling the operator to create a record for each of a plurality of patients, a task list zone displaying all steps and sub-steps of a CT scan to be performed for a selected patient based on a selected scan protocol, a settings zone and a scanning zone displaying and enabling operator selection of scan parameters related to the selected scan protocol for the selected patient, and a dose area zone displaying a relationship between the selected scan parameters and a radiation dosage experienced by the patient based thereon. | 04-10-2014 |
Paul Wimmer, Maple Valley, WA US
Patent application number | Description | Published |
---|---|---|
20120198019 | WEB SERVICE SUPPORT FOR BULK ITEM EXPORT/IMPORT - A method for migrating, archiving, or backing-up data between a first device and a second device hosting a communication application in a networked computing environment. The method includes retrieving mailbox data from the second device, the mailbox data includes messaging data and configuration data of the communication application associated with the mailbox data. The method also includes mapping the mailbox data from a first data format to a second data format, and transferring the mapped mailbox data to the first device as a first file. | 08-02-2012 |
Ralph E. Wimmer, Simpsonville, SC US
Patent application number | Description | Published |
---|---|---|
20110094644 | INTEGRATED TIRE SECTION REPAIR - Methods of repairing tire portions have steps that include removing at least part of the damaged portion of the tire to form an aperture or opening through the tire; forming one or more grooves in the tire adjacent to and extending from the aperture; placing at least one repair reinforcement within each of the one or more grooves; placing a patch on the tire to cover the aperture and each repair reinforcement; and, applying material to fill the remainder of the opening. | 04-28-2011 |
Richard Alfons Wimmer, Redwood City, CA US
Patent application number | Description | Published |
---|---|---|
20150301781 | SEAMLESS ILLUMINATED PANEL - A device and method of providing a versatile illuminated panel for walls, product displays, and other surfaces is described. Panels are constructed from a variable number of rectangular illuminated tiles, where the tiles mate edge-to-edge so as to create a nearly seamless visual panel effect. Illumination within each tile is uniform to also create a nearly seamless visual panel effect. End-users may create panels of varying sizes and shapes by using different quantities of a standard tile. The software within the invention automatically determines the number and arrangement of tiles within each assembled panel. Each tile comprises a plurality of illuminators, an optical means to distribute light from the illuminators uniformly across the tile, and at least one communication interface. In one embodiment the tiles are linked into a communications tree-structure; and the location of each tile within the tree constitutes its logical address. | 10-22-2015 |
Robert J. Wimmer, Hastings, MN US
Patent application number | Description | Published |
---|---|---|
20080297093 | Systems and Methods for Reduction of Cross Coupling in Proximate Signal Lines - Various systems and methods for reducing cross coupling in proximate signals are disclosed. As one example, a system for reducing cross-coupling in adjacent signals that includes an active slew rate limiter circuit is disclosed. The active slew rate limiter circuit is operable to receive an input signal, and to provide an output signal based on the input signal with a controlled slew rate. In some cases, such systems may be included within a storage device that includes a read head. In such cases, the systems may operate to assure a substantially constant power dissipation within the read head. | 12-04-2008 |
Wilson J. Wimmer, Hudson, NH US
Patent application number | Description | Published |
---|---|---|
20100039311 | System and Method for Generating an Alert Signal in a Detection System - A system and method for generating alert signals in a detection system is described. The system compares data extracted from signals received via receive antenna beams with stored scenarios and determines whether to generate an alert signal based upon the results of the compare operation. The comparison of data extracted from received signals with stored scenarios can be accomplished by using one or more latches to process the extracted data from the received signals. In one embodiment, raw detections are pre-processed to generate so-called field of view (FOV) products. The FOV products are then provided to a tracker. In another embodiment, rather than pre-process the raw detections, the raw detections are instead provided directly to a tracker which processes the raw detections to provide products including, but not limited to, relative velocity and other parameters. | 02-18-2010 |
20100238066 | Method and system for generating a target alert - A method of generating a target alert includes combining one or more object detection range values, an object relative velocity value, and a host vehicle velocity value to identify an alert. A system for generating a target alert includes a detection processor to provide one or more detection range values, a transceiver to receive a host vehicle velocity value, a relative velocity calculation processor to calculate a relative velocity value and an alert identification processor to combine the one or more detection range values, the relative velocity value, and the host vehicle velocity value to identify the alert. | 09-23-2010 |