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Wimmer, US

Eckard Wimmer, East Setauket, NY US

Patent application numberDescriptionPublished
20100209454ATTENUATED VIRUSES USEFUL FOR VACCINES - This invention provides an attenuated virus which comprises a modified viral genome containing nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce synonymous deoptimized codons into the genome. The instant attenuated virus may be used in a vaccine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated virus. Further, this invention further provides a method for preventing a subject from becoming afflicted with a virus-associated disease comprising administering to the subject a prophylactically effective dose of a vaccine composition comprising the instant attenuated virus.08-19-2010

Eckard Wimmer, E. Setauket, NY US

Patent application numberDescriptionPublished
20090246216NOVEL ATTENUATED POLIOVIRUS - A novel and stable attenuated poliovirus, which replicates in neuroblastoma cells, is produced by engineering an indigenous replication element (cre), into the 5′ non-translated genomic region and inactivating the native cre element located in the coding region of 2C (mono-crePV). The stably attenuated poliovirus replicates in a neuroblastoma model (Neuro-2a10-01-2009
20120064113Novel Attenuated Poliovirus - A novel and stable attenuated poliovirus, which replicates in neuroblastoma cells, is produced by engineering an indigenous replication element (cre), into the 5′ non-translated genomic region and inactivating the native cre element located in the coding region of 2C (mono-crePV). The stably attenuated poliovirus replicates in a neuroblastoma model (Neuro-2a03-15-2012

Frank Lee Wimmer, Raleigh, NC US

Patent application numberDescriptionPublished
20120233573TECHNIQUES TO PRESENT HIERARCHICAL INFORMATION USING ORTHOGRAPHIC PROJECTIONS - Techniques to present hierarchical information as orthographic projections are described. An apparatus may comprise an orthographic projection application arranged to manage a three dimensional orthographic projection of hierarchical information. The orthographic projection application may comprise a hierarchical information component operative to receive hierarchical information representing multiple nodes at different hierarchical levels, and parse the hierarchical information into a tree data structure, an orthographic generator component operative to generate a graphical tile for each node, arrange graphical tiles for each hierarchical level into graphical layers, and arrange the graphical layers in a vertical stack, and an orthographic presentation component operative to present a three dimensional orthographic projection of the hierarchical information with the stack of graphical layers each having multiple graphical tiles. Other embodiments are described and claimed.09-13-2012

Markus Wimmer, Chicago, IL US

Patent application numberDescriptionPublished
20100010630PLASTIC IMPLANT IMPREGNATED WITH A DEGRADATION PROTECTOR - A plastic implant device for a mammal that contains a rare earth metal compound tracer and a method for detecting degradation such as wear of the implanted device are disclosed. The tracer can also be present with a separate antioxidant or the tracer compound can be can be the salt of a C01-14-2010
20100174372PLASTIC IMPLANT IMPREGNATED WITH A DEGRADATION PROTECTOR - A plastic implant device for a mammal that contains a rare earth metal compound tracer and a method for detecting degradation such as wear of the implanted device are disclosed. The tracer can also be present with a separate antioxidant or the tracer compound can be can be the salt of a C07-08-2010

Paul Wimmer, Maple Valley, WA US

Patent application numberDescriptionPublished
20120198019WEB SERVICE SUPPORT FOR BULK ITEM EXPORT/IMPORT - A method for migrating, archiving, or backing-up data between a first device and a second device hosting a communication application in a networked computing environment. The method includes retrieving mailbox data from the second device, the mailbox data includes messaging data and configuration data of the communication application associated with the mailbox data. The method also includes mapping the mailbox data from a first data format to a second data format, and transferring the mapped mailbox data to the first device as a first file.08-02-2012

Ralph E. Wimmer, Simpsonville, SC US

Patent application numberDescriptionPublished
20110094644INTEGRATED TIRE SECTION REPAIR - Methods of repairing tire portions have steps that include removing at least part of the damaged portion of the tire to form an aperture or opening through the tire; forming one or more grooves in the tire adjacent to and extending from the aperture; placing at least one repair reinforcement within each of the one or more grooves; placing a patch on the tire to cover the aperture and each repair reinforcement; and, applying material to fill the remainder of the opening.04-28-2011

Robert J. Wimmer, Hastings, MN US

Patent application numberDescriptionPublished
20080297093Systems and Methods for Reduction of Cross Coupling in Proximate Signal Lines - Various systems and methods for reducing cross coupling in proximate signals are disclosed. As one example, a system for reducing cross-coupling in adjacent signals that includes an active slew rate limiter circuit is disclosed. The active slew rate limiter circuit is operable to receive an input signal, and to provide an output signal based on the input signal with a controlled slew rate. In some cases, such systems may be included within a storage device that includes a read head. In such cases, the systems may operate to assure a substantially constant power dissipation within the read head.12-04-2008

Wilson J. Wimmer, Hudson, NH US

Patent application numberDescriptionPublished
20100039311System and Method for Generating an Alert Signal in a Detection System - A system and method for generating alert signals in a detection system is described. The system compares data extracted from signals received via receive antenna beams with stored scenarios and determines whether to generate an alert signal based upon the results of the compare operation. The comparison of data extracted from received signals with stored scenarios can be accomplished by using one or more latches to process the extracted data from the received signals. In one embodiment, raw detections are pre-processed to generate so-called field of view (FOV) products. The FOV products are then provided to a tracker. In another embodiment, rather than pre-process the raw detections, the raw detections are instead provided directly to a tracker which processes the raw detections to provide products including, but not limited to, relative velocity and other parameters.02-18-2010
20100238066Method and system for generating a target alert - A method of generating a target alert includes combining one or more object detection range values, an object relative velocity value, and a host vehicle velocity value to identify an alert. A system for generating a target alert includes a detection processor to provide one or more detection range values, a transceiver to receive a host vehicle velocity value, a relative velocity calculation processor to calculate a relative velocity value and an alert identification processor to combine the one or more detection range values, the relative velocity value, and the host vehicle velocity value to identify the alert.09-23-2010