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Williams, PA

Alan M. Williams, Easton, PA US

Patent application numberDescriptionPublished
20090158821DEVICES, METHODS AND SYSTEMS FOR MEASURING ONE OR MORE CHARACTERISTICS OF A SUSPENSION - A device, method and system for measuring one or more ultrasound parameters of a suspension comprising particles dispersed in a liquid carrier comprising, an immersible devices, comprising, one or more ultrasonic probes; a reflector having staggered reflective; a housing having an opening into the housing to allow the suspension to flow into the space between the probe surface and the reflective surface; an ultrasound wave generator/receiver device; and a signal processing device.06-25-2009
20100046322METHOD AND APPARATUS FOR FORMING AN HOMOGENEOUS MIXTURE OF CHROMATOGRAPHY MEDIA IN A VESSEL - The present invention relates to methods and apparatus for forming an homogeneous mixture of chromatography media in a vessel. The invention also relates to methods and apparatus for transferring the homogeneous media from the vessel into a second vessel in preparation for packing a chromatography column. The invention can also be used directly to pack the column with homogeneous media.02-25-2010
20100219115SYSTEM AND METHOD FOR ASSEMBLING A LARGE SCALE CHROMATOGRAPHY STRUCTURE - A container system is disclosed, where the container system includes a housing. A chromatography cartridge is disposed in the housing. A structural support in the housing is configured to retain the chromatography cartridge within the housing. The housing is configured to withstand a certain amount of pressure generated inside the chromatography cartridge. The chromatography cartridge is disposed in the housing either in horizontal or in vertical position.09-02-2010
20100313992SYSTEM AND METHOD FOR THE AUTOMATION OF COLUMN AND MEDIA PACKING - This invention provides for the fully automated, hands free, packing of chromatography columns by means of delivering a pre-calculated volume of slurry and using two different packing modalities to stop the packing when either 1) this volume has been delivered in the column, or 2) when the adapter is moved to reach a bed height corresponding to the pre-calculated volume. Thus, a chromatography column can be packed in a fully automated fashion and such a column is 1) stable and 2) has the desired performance characteristic.12-16-2010
20110073548SEPARATION SYSTEM AND METHOD - A separation system comprises (i) at least two separation units, each separation unit comprising a fluid inlet and a fluid outlet, wherein the separation units are connected in series outlet to inlet to form a line of separation units, and (ii) sensing and adjustment means, provided in-line between each separation unit, for continuously monitoring and adjusting at least one environmental property parameter of fluid flowing from one separation unit to a subsequent separation unit in the line of separation units. Uses of the separation system and a method for purification of a liquid containing a desired species, using separation units and in-line adjustment of a fluid flow or flows, are also disclosed.03-31-2011

Patent applications by Alan M. Williams, Easton, PA US

Brian Williams, York, PA US

Patent application numberDescriptionPublished
20100120282PUSH-PULL CONNECTOR - A connector assembly configured to engage a mating connector. The connector assembly includes a plug body that has loading and mating ends and a central axis extending therebetween. The mating end is configured to be inserted into a cavity of the mating connector to establish at least one of communicative and power connections. The plug body has an outer surface that surrounds and faces away from the central axis. The connector assembly also includes a ring that is slidably mounted over the plug body. The ring is configured to slide along the outer surface of the plug body in an axial direction between withdrawn and locked positions. The connector assembly also includes a sleeve member that is slidably mounted over the plug body and the ring. The sleeve member includes a plurality of fingers that extend toward the mating end and are biased toward the outer surface of the plug body. The ring is configured to engage the fingers thereby causing the fingers to flex outward away from the outer surface and engage the mating connector.05-13-2010

Brian J. Williams, York, PA US

Patent application numberDescriptionPublished
20110281451CONNECTOR ASSEMBLIES INCLUDING MOVABLE CONNECTORS - A connector assembly including a first connector configured to be movably mounted to a support structure and having a first mating terminal. The first connector is movable with respect to the support structure in an axial direction along an alignment axis. The connector assembly also includes a second connector that is configured to be movably mounted to a support panel and has a second mating terminal. The second connector is movable with respect to the support panel in a radial direction relative to an alignment axis. The second connector shifts in the radial, direction to align the first and second mating terminals when the first and second connectors engage each other in a misaligned manner. The first connector moves between a projected position and a retracted position along the alignment axis to facilitate establishing a communication pathway between the first and second mating terminals.11-17-2011
20120077392CONTACT RAIL FOR A JUNCTION BOX - A contact rail is provided including a module coupling end and a mating end. A diode mounting surface is positioned between the module coupling end and the mating end. A pivot member extends from a base of the module coupling end. The pivot member is configured to be engaged by an elongated tool. A module coupling fastener engages the base of the module coupling end. The elongated tool is configured to engage the module coupling fastener. The elongated tool is configured to pivot about the pivot member to separate the module coupling fastener from the base of the module coupling end so that a contact from a power module is receivable between the base of the module coupling end and the module coupling fastener.03-29-2012

Brian James Williams, York, PA US

Patent application numberDescriptionPublished
20100032205HIGH PERFORMANCE CABLE SPLICE - A cable repair system having a splicing member. The splicing member includes at least two conductor pairs and an insulation member disposed intermediate to the at least two conductor pairs. The insulation member is configured to shield the conductor pairs from electrical interference from adjacent conductor pairs. The conductor pairs and insulation member are configured to permit splicing of two more cable segments. A method for splicing a data cable and a repaired cable are also disclosed.02-11-2010
20100240246CONNECTOR ASSEMBLY WITH A LIGHT INDICATIVE OF A CONNECTOR STATUS - A connector assembly includes a housing, a light source located within the housing, and a cover element covering at least a portion of a mating face of the housing. The housing includes a connector that is arranged to electrically mate with a peripheral connector proximate to the mating face of the housing. The light source generates light directed toward the mating face of the housing to indicate a status of the connector. The cover element includes a light transmissive area that is positioned to receive the light generated by the light source and transmit the light outward from the mating face in order to indicate the status of the connector.09-23-2010

Bruce Williams, Narvon, PA US

Patent application numberDescriptionPublished
20110140491BASE RETAINING SYSTEM WITH A BELT TENSION INDICATOR - An infant safety seat with an adjustable accommodating space includes a multi-layer cushioning insert which is detachably insertable into an infant safety seat for accommodating an infant in different stages of growth with different sizes. The multi-layer cushioning insert comprises a first cushioning part and a second cushioning part both may detachably to overlap each other and connect into the accommodating space to provide the necessary support for keeping an infant in proper postural position. The first cushioning part includes a U-shaped head cushion part, U-shaped body cushion part and U-shaped leg cushion part for restricting the side moving of the infant. Further, for accommodating a smaller infant, the second cushioning part can be detachably overlapped onto the first cushioning part for further reducing the side moving space and upright moving space of the baby in the infant safety seat.06-16-2011
20110169309INCLINATION ADJUSTMENT MECHANISM FOR A BASE OF SAFETY SEAT - An inclination adjustment mechanism for a base of safety seat includes a base, a heelpiece and a spring-loaded press button. The base has one end formed with a plurality of positioning indents, and a upper surface for supporting a safety seat. The heelpiece is pivoted to the base and formed with a protruded portion for selectively engaging with one of the positioning indents thereby to keep the base in a selected inclination position. The spring-loaded press button is operatively connected to one end of the heelpiece for releasing the protruded portion from the positioning indents, so as to change the selected inclination position of the base by pressing the spring-loaded press button and moving one end of the base relative to the heelpiece.07-14-2011
20110170948QUICK RELEASE LOCKING MECHANISM FOR SECURING AN INFANT CARRIER TO A BASE - A quick release locking mechanism for securing an infant carrier to a base, includes at least a transversal bar, a spring-loaded locking element, a manipulating element and a linking element. The infant carrier is formed with a downward holding slot on the underside thereof, and the base is formed with a upper surface for supporting the infant carrier thereon. The transversal bar is fixed on the base in a position relative to the downward holding slot. The spring-loaded locking element is pivoted on the infant carrier for closing the downward holding slot and retaining the transversal bar within the downward holding slot automatically while the infant carrier is resting on the base. The linking element is connected between the spring-loaded locking element and the manipulating element, and the manipulating element is operatively mounted on the infant carrier for driving the spring-loaded locking element in a remote position.07-14-2011
20110233903 EASY LOCK AND RELEASE MECHANISM FOR A SAFETY SEAT RETAINING ON A STROLLER FRAME AND A BASE - An easy lock and release mechanism for a safety seat retaining on a stroller frame and a base, comprising a base, a stroller frame, a safety seat, and a release mechanism. The base has two transversal bars for detachably connecting with the safety seat. The stroller frame has two sides, two spring-loaded latches and a front confinement. The front confinement is stretched between the two sides of the stroller frame. The spring-loaded latch is projectively and retractively mounted at the front confinement for detachably connecting with the safety seat. The safety seat has a front end, a rear end, two anchoring slots, two latching elements and two positioning protrusions, the two positioning protrusions protruded downwardly for resting within the positioning indent and each formed with an orifice for engaging with the spring-loaded latch thereby retaining the safety seat on the stroller frame. The two anchoring slots is capable of anchoring on the two transversal bars and locked by the two latching elements. The release mechanism has a release actuator, two pushing elements and two flexible lengths; wherein the pushing element is driven by the release actuator for pushing the spring-loaded latch away from the orifice thereby releasing the safety seat from the stroller frame. The two flexible lengths each having one end connected with the release actuator and another end for connected with the two latching elements for unlocking the two transversal bars from the two anchoring slots.09-29-2011
20120181829Child Safety Seat - A child safety seat includes a seat shell, a headrest and a latch. The seat shell has a seat portion and a backrest portion, the backrest portion having a rear surface, and a front surface for supporting a child's back. The headrest is adjustable along the backrest portion. The latch is accessible from the rear surface of the backrest portion, wherein the latch is biased to lock the headrest in position relative to the backrest portion.07-19-2012

Bruce L. Williams, Denver, PA US

Patent application numberDescriptionPublished
20090127828FOLDING STROLLER ACTUATING SYSTEM - An actuating system for a foldable stroller including a foldable stroller frame having left and right front legs and left and right rear legs and a wheel mounted to each leg. The frame includes an operator handle having left and right support rails extending therefrom and connected to the left and right rear legs. At least one locking member is movably connected to at least one the support rails and biased toward a locking position to secure the connection between the left and right support rails and the left and right rear legs. A support member having an actuator connected thereto is connected between the left and right support rails. The actuator is coupled to the at least one locking member. An operator tray is removably connected to the support member and includes at least one recess formed therein for receiving at least a portion of the actuator.05-21-2009
20100019557CHILD TRAVEL SEAT RESTRAINT SYSTEM - A restraint system for a child travel seat which includes a frame dimensioned to rest upon a vehicle seat. The frame defines front and rear portions and a center line. An adjustment assembly is coupled to the frame and positioned at a selected one of the front and rear portions of the frame. A strap assembly is connected to the adjustment assembly. The strap assembly has first and second points removably securable to a vehicle anchor and a third point movably secured within the adjustment assembly.01-28-2010
20120056452SYSTEM FOR ENGAGING MULTI-COMPONENT CARSEAT - A system for locking together the base and passenger seat of a multi-part carseat. The system includes a base and a passenger seat. The base has upper surface that receives a passenger seat, a center line defining front and rear ends, opposed sides extending between the ends, and two spaced apart locking points positioned rearwardly of the center line and two spaced apart locking points positioned forward of the centerline. The passenger seat is dimensioned to be received by the upper surface of the base and includes four locking elements that are respectively positioned and configured for releasable engagement with a respective one of the four locking points of the base. An actuator releases the locking engagement between the locking elements of the seat and the locking points of the base.03-08-2012

Patent applications by Bruce L. Williams, Denver, PA US

Bruce L. Williams, Narvon, PA US

Patent application numberDescriptionPublished
20120013154Child Safety Seat Assembly - A child safety seat assembly comprises a child seat, a base adapted to assemble with the child seat, wherein the base includes a first portion having an enlarged bottom, and an inclined second portion joined with an upper side of the first portion and provided with a storage pocket, and an abuttal support operable to slide relative to the base between a first position stowed in the storage pocket and a second position deployed outward.01-19-2012
20120013159Child Safety Seat - A child seat can comprise a seat shell having two protruding rails extending at an underside of the seat shell, at least four latches disposed in two symmetric pairs adjacent to the two rails, wherein the latches are operable to lock the child seat with a base, and a release mechanism operable to drive the latches to unlock from the base.01-19-2012
20120013160Child Safety Seat Assembly - A child safety seat assembly includes a child seat and a base. In one embodiment, the base can include a first portion having a bottom adapted to provide stable resting support, and a second portion extending upward from the first portion. The child seat can be installed on the base, wherein the child seat has a seat portion and a seatback, and is movable relative to adjust a distance between the seat portion and a region of the second portion in front of the seat portion. In other embodiments, a base suitable for use with a child seat is also described. The base can comprise a shell body, and an adjustable platform movably assembled on an upper guide surface of the shell body, wherein the adjustable platform is adapted to attach with the child seat.01-19-2012
20120104808Infant Safety Seat - An infant safety seat comprises a seat shell, a handle and at least a latch element mounted between the seat shell and the handle. Two sides of the seat shell are provided with first coupling elements, each of which includes multiple locking grooves. Two sides of the handle has second coupling elements that are pivotally connected with the first coupling elements, each of the second coupling elements having an interior defining a guide slot. The latch element is movably assembled in the guide slot and includes at least a first stud, the latch element being operable to switch between a locked state where the first stud is engaged with one of the locking grooves to hold the handle in place, and an unlocked state where the first stud is disengaged from the locking grooves to allow rotation of the handle relative to the seat shell.05-03-2012
20120181822Child Safety Seat Assembly - A child safety seat assembly includes a base and a child seat. The base comprises a shell body, and a support platform provided at an upper side of the shell body on which the child seat can be installed. The shell body includes a first portion having a bottom adapted to provide stable resting support, and a second portion extending upward from the first portion, wherein the shell body includes a storage cavity accessible from an outer side of the second portion. The storage cavity can be sized to receive free end portions of a restrain strap used for holding the base in place.07-19-2012
20120326474Child Safety Seat - A child safety seat comprises a seat shell, two first latches, two second latches and a release handle. An underside of the seat shell has two protruding rails, each of which having an inner side surface facing a gap delimited between the two rails, and an outer side surface opposite to the inner side surface. The two first latches are assembled with the rails, and respectively protrude from the inner side surfaces of the two rails to engage with a base. The two second latches are assembled at positions adjacently opposite to the first latches, and respectively protrude from the outer side surfaces of the two rails to engage with a stroller frame. The release handle is operatively connected with the first and second latches at the two rails, and is operable to switch the first and second latches from a locking to unlocking state.12-27-2012

Catherine T. Williams, Kennett Square, PA US

Patent application numberDescriptionPublished
20100085568Dual Sample Mode Spectrophotometer - A dual-mode method and apparatus of selectively measuring samples in either a vessel or as a surface tension retained sample held between two opposing pedestals is introduced. In either configuration, such modes further contain optical paths from a source system through a small-volume or large-volume sample to a spectrometer based system. Such a system enables a user to measure samples with absorbances ranging from about 0.005 up to about 2.0 Absorbance Units for any given wavelength.04-08-2010

Charles M. Williams, Landsdale, PA US

Patent application numberDescriptionPublished
20080272163Carrying Assembly - An assembly for carrying a cellular phone having a cradle adapted to receive and releasably hold the phone therein, a base adapted to be releasably connected to an article, and means for releasably connecting said cradle to said base. The cradle has a body portion and side members fixed to the body portion and shaped to conform to the contour of the phone. The base has base plate and means for releasably connecting the base plate to the article. The connection means includes a male fixture fixed to the base plate and having an annular groove; a cutout in the base plate adapted to receive said male fixture; and, a locking plate that that can be reciprocated from a first position engaging the annular groove to lock the male fixture within the cutout, and a second position disengaged from the annular groove that permits the male fixture to be withdrawn from the cutout.11-06-2008

Charles R. Williams, Gibsonia, PA US

Patent application numberDescriptionPublished
20120059087PRESSURE SENSITIVE ADHESIVES BASED ON RENEWABLE RESOURCES AND RELATED METHODS - Pressure sensitive adhesives produced from naturally occurring fats and oils are described. Also described are methods of producing the pressure sensitive adhesives. Generally, one or more naturally occurring fats or oils are epoxidized, and then reacted with certain alcohols or amines to thereby obtain the noted pressure sensitive adhesives.03-08-2012

Charles T. Williams, Bristol, PA US

Patent application numberDescriptionPublished
20090241983Abrasive Dental Floss and Method of Making Same - Polytetrafluoroethylene (PTFE) flosses have abrasives added to the floss fiber that increase the abrasion to teeth surfaces, and thus result in a floss that provides enhanced cleaning of surfaces of teeth that face interstices between teeth. Floss fiber is formed by loading a PTFE resin with an abrasive filler. The PTFE resin and filler are processed to form a floss fiber with a surface that provide enhanced abrasion properties.10-01-2009

Charles Todd Williams, Pittsburgh, PA US

Patent application numberDescriptionPublished
20110319586Ketal Compounds from Polyols and Oxocarboxylates - Novel ketal compounds can be made from an oxocarboxylate and a triol. Novel polymeric structures are, in turn, synthesized from the ketal compounds. Such ketal compounds and associated polymers are useful in a broad range of applications as a substitute for materials derived from petroleum or other such nonrenewable resources.12-29-2011
20120256139UV-CURABLE COATING CONTAINING CARBON NANOTUBES - The present invention provides a conductive, curable coating made from about 0.01 wt. % to about 5 wt. %, of multi-walled carbon nanotubes, having a diameter of greater than about 4 nm, about 10 wt. % to about 99 wt. % of an aliphatic urethane acrylate and about 0.1 wt. % to about 15 wt. % of a photoinitiator, wherein the coating is curable by exposure to radiation and wherein the cured coating has a surface resistivity of about 1010-11-2012
20120258302FLEXIBLE SENSING MATERIAL CONTAINING CARBON NANOTUBES - The present invention relates to a flexible sensing material made from (a) at least one flexible polymeric layer and (b) at least one conductive, curable coating layer containing about 0.01 wt. % to about 5 wt. % of multi-walled carbon nanotubes having a diameter of greater than about 4 nm, about 10 wt. % to about 99 wt. % of an aliphatic urethane acrylate and about 0.1 wt. % to about 15 wt. % of a photoinitiator, wherein the weight percentages are based on the weight of the formulation, wherein the coating layer is curable by exposure to radiation and wherein the cured coating layer has a surface resistivity of about 1010-11-2012

Charles Todd Williams, Pittsburg, PA US

Patent application numberDescriptionPublished
20110021658Polyketal Compounds, Synthesis, and Applications - The invention relates to polyketal compounds. The compounds are synthesized by the selective ketalization of oxocarboxylic acids, e.g. keto acids and semialdehydes, and esters thereof with tetrols and higher polyols that products two or more cyclic ketal ester moieties per molecule, wherein the cyclic ketal moieties are situated in a bis-, tris-, or polyketal conformation. The invention further relates to applications of these compounds and subsequent reactions thereof.01-27-2011

Daniel Clement Williams, Elkins Park, PA US

Patent application numberDescriptionPublished
20090012995Method and apparatus for capture and distribution of broadband data - A system and method for preparing for distribution to, distributing to and/or use by one or more devices broadband data associated with intelligence information garnered from an aerial vehicle (“AV”): The method may include obtaining from sensors coupled to the AV video depicting an area of surveillance, obtaining metadata associated with the video, aligning, temporally, the video and metadata, using reference information to align, spatially, the video and metadata, forming for distribution to the at least one device enhanced metadata as a function of the video, metadata and reference information, wherein the enhanced metadata is operable to enable displaying at the devices at least a portion of the video, whereby after receiving a distribution of the enhanced metadata, the devices are operable to display such portion of the video.01-08-2009

Darryl Williams, Philadelphia, PA US

Patent application numberDescriptionPublished
20090082611Uniform field magnetization and targeting of therapeutic formulations - Systems and methods for magnetic targeting of therapeutic particles are provided. Therapeutic particles comprise one or more magnetic or magnetizable materials and at least one therapeutic agent. Therapeutic particles are specifically targeted using uniform magnetic fields capable of magnetizing magnetizable materials, and can be targeted to particular locations in the body, or can be targeted for capture, containment, and removal. Also provided are bioresorbable nanoparticles prepared without the use of organic solvents, and methods for therapeutically using such bioresorbable nanoparticles.03-26-2009
20090216320Magnetic Gradient Targeting And Sequestering Of Therapeutic Formulations And Therapeutic Systems Thereof - A therapeutic system and a method that uses stents, and/or other implantable devices (08-27-2009
20100210015PHOTOCHEMICAL ACTIVATION OF SURFACES FOR ATTACHING BIOMATERIAL - A water-soluble photo-activatable polymer including: a photo-activatable group adapted to be activated by an irradiation source and to form a covalent bond between the water-soluble photo-activatable polymer and a matrix having at least one carbon; a reactive group adapted to covalently react with a biomaterial for subsequent delivery of the biomaterial to a cell; a hydrophilic group; and a polymer precursor. A composition including a monomolecular layer of the water-soluble photo-activatable polymer and a matrix having at least one carbon, wherein the monomolecular layer is covalently attached to the matrix by a covalent bond between the photo-activatable group and the at least one carbon. The composition further includes a biomaterial having a plurality of active groups, wherein the biomaterial is covalently attached to the monomolecular layer by covalent bonding between the active groups and reactive groups. Also provided is a method for delivery of a biomaterial to a cell.08-19-2010
20130011370Uniform Field Magnetization and Targeting of Therapeutic Formulations - Systems and methods for magnetic targeting of therapeutic particles are provided. Therapeutic particles comprise one or more magnetic or magnetizable materials and at least one therapeutic agent. Therapeutic particles are specifically targeted using uniform magnetic fields capable of magnetizing magnetizable materials, and can be targeted to particular locations in the body, or can be targeted for capture, containment, and removal. Also provided are bioresorbable nanoparticles prepared without the use of organic solvents, and methods for therapeutically using such bioresorbable nanoparticles.01-10-2013

Patent applications by Darryl Williams, Philadelphia, PA US

Dennis R. Williams, Collegeville, PA US

Patent application numberDescriptionPublished
20120149749METHOD OF TREATING THROMBOCYTOPENIA - Invented is a method of treating thrombocytopenia in a human in need thereof which comprises the administration of a therapeutically effective amount of a 3′-{N′-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydropyrazol-4-ylidene]hydrazino}-2′-hydroxybiphenyl-3-carboxylic acid to such human.06-14-2012

Douglas R. Williams, Allentown, PA US

Patent application numberDescriptionPublished
20090113712Modular Cryogenic Liquid Storage Systems - Method of designing a customer station adapted to receive a cryogenic liquid, store the cryogenic liquid, discharge the cryogenic liquid after storage, and either provide the cryogenic liquid as a liquid product to a user or vaporize the cryogenic liquid to provide a gas product to a user. The method comprises selecting design parameters including product type, range of product flow rates, and required pipe diameters and piping types. Standardized piping skids are designed for one or more of the combinations of product type, pipe size, and pipe type. The product requirements of a user are defined, the type of cryogenic liquid storage tank is determined, and a piping skid design for the required service is selected from the standardized piping skid designs. The customer station then is designed using the selected standardized piping skid design and the selected type of cryogenic storage tank.05-07-2009
20090211264Modular Cryogenic Liquid Storage Systems - Industrial gas customer station components comprising a plurality of cryogenic storage tanks each having top and bottom nozzles in flow communication with first and second tank piping connection points, respectively, disposed at a defined distance apart, thereby providing standardized first and second tank piping connection points, and a plurality of piping skids each comprising first and second pipe sections having first and second ends, the first ends thereof defining first and second piping skid connection points disposed at a defined distance apart, thereby providing standardized first and second piping skid connection points. The defined distances between the respective first and second piping skid connection points and the first and second tank piping connection points are essentially equal. The components include a tanker fill connection adapted to receive cryogenic liquid from a cryogenic liquid tanker wherein the connection is in flow communication with the first and second piping skid connection points.08-27-2009

Douglas S. Williams, Philadelphia, PA US

Patent application numberDescriptionPublished
20090275547METAL COMPLEX PHOSPHATIDYL-INOSITOL-3-KINASE INHIBITORS - Provided are novel organometallic compounds that inhibit PI3K lipid kinase and phospho-AKT in human melanoma cells, and also inhibit the migration of melanoma cells. The present invention is also directed to methods for inhibiting cancer cell proliferation, migration or both comprising contacting a cancer cell with a disclosed organometallic kinase inhibitor. Also disclosed are methods for treating a kinase-affected disease or condition comprising administering to a subject in need thereof a therapeutically effective amount of a disclosed organometallic kinase inhibitor.11-05-2009

Drew E. Williams, Blue Bell, PA US

Patent application numberDescriptionPublished
20090121174Liquid-applied sound damping - A liquid applied sound damping composition with a binder having from 0.05 wt. % to 20 wt. %, based on the total weight of polymer solids, of carboxy acid monomers, present as copolymerized monomers in pendant polyacid sidechain groups.05-14-2009
20110263757DURABLE THERMOSET BINDER COMPOSITIONS FROM 5-CARBON REDUCING SUGARS AND USE AS WOOD BINDERS - The present invention provides thermosetting aqueous binder compositions of (i) one or more diprimary diamine, e.g. lysine, or poly(primary amine), e.g. polyethylenimine and tris(2-aminoethyl)amine, and (ii) one or more 5-carbon reducing sugar, such as xylose. The binders are at least substantially formaldehyde free and cure rapidly at temperatures sufficiently low and with sufficiently little swelling to enable one to provide wood or woody material containing articles, such as particle board, oriented strand board and bamboo boards or articles.10-27-2011

Patent applications by Drew E. Williams, Blue Bell, PA US

Drew Elliot Williams, Blue Bell, PA US

Patent application numberDescriptionPublished
20120135152STABLE REACTIVE THERMOSETTING FORMULATIONS OF REDUCING SUGARS AND AMINES - The present invention provides stable aqueous thermosetting binder compositions having a total solids content of 15 wt. % or higher, preferably, 20 wt. % or higher, and having extended shelf life comprising one or more reducing sugar, one or more primary amine compound, and one or more stabilizer acid or salt having a pKa of 8.5 or less. The total amount of stabilizer used may range from 5 to 200 mole %, based on the total moles of primary amine present in the binder. The stabilizer may be an organic stabilizer chosen from a monocarboxylic acid, a dicarboxylic acid, a fatty acid, an acid functional fatty acid ester, an acid functional fatty acid ether, or an inorganic stabilizer chosen from a mineral acid, a mineral acid amine or ammonia salt, and a Lewis acid, and mixtures thereof. The compositions can be used to provide binders for substrate materials including, for example, glass fiber.05-31-2012

Edward D. Williams, Philadelpha, PA US

Patent application numberDescriptionPublished
20130029291Dual use exercise whitener appliance - A jaw-joint protective device is provided for whitening and brightening a wearer's teeth while protecting the teeth, tongue, lips, jaw, and other delicate structures of the vital cranial triad (VCT) from injury and/or for supporting the condyle of the temporomandibular joint (TMJ) in a relatively fixed (stable) position thereby stabilizing the jaw and the VCT during head contact activity, exercise, physical rehabilitation, C-force acceleration, teeth grinding disorders and sleep apnea and or permit the components of a VCT disorder to be realigned for proper healing. This device is an over-the-counter purchased, boil and bite device for whitening at least one tooth while protecting the jaw-joint, providing maxillary and mandibular teeth seats for protection of the mouth and/or healing of the VCT. This invention provides a device for customized fitting that is purchased over-the-counter that is versatile for protecting not only the mouth but also a larger area, the vital cranial triad which includes the TMJ, while at the same time allows for audible speech, reduces sleep disorders of snoring, grinding and clenching of teeth with additional benefits.01-31-2013

Frank C. Williams, Freeport, PA US

Patent application numberDescriptionPublished
20110098394COATING COMPOSITION COMPRISING AN ALKOXYSILANE, A POLYSILOXANE, AND A PLURALITY OF PARTICLES - The present invention is directed to a coating composition, such as a substantially clear coating composition, which comprises (1) an alkoxysilane, (2) a polysiloxane, (3) a plurality of particles, and (4) curing agent that is reactive with the polysiloxane. The coating composition of the present invention can exhibit increased physical properties, such as scratch resistance, when compared to similar coating compositions that lack the components disclosed herein.04-28-2011

George Williams, Doylestown, PA US

Patent application numberDescriptionPublished
20100314083Condenser Shell and Tube Bundle Support Plate Construction - A condenser shell internal support structure includes horizontal rails and vertical beams which can individually support a variety of shapes and configurations of tube bundle modules. Each module includes an end frame and longitudinal framework members that hold each of the parallel tube bundle support plates. The reinforcement framework supports at least one tube bundle and also opposing sidewalls of the shell. The framework further comprises laterally disposed crossbeams extending between and affixed to the opposing shell sidewalls.12-16-2010

George J. Williams, Doylestown, PA US

Patent application numberDescriptionPublished
20090032230Support plate for separate and independent tube bundles - A support plate apparatus capable of separately supporting two or more independent tube bundles within a heat exchanger is described. The apparatus includes at least one bundle support plate and at least two tube bundles. Bundle support plates are separately disposed and substantially parallel. Each bundle support plate has at least two openings. Each opening along one the bundle support plate is dimensioned, located, and aligned in a complimentary arrangement with one opening along each remaining bundle support plates. Each tube bundle includes at least two grids each comprised of interlocking plates and a plurality of tubes. Each tube bundle is disposed within one complimentary arrangement of the openings. Each grid is disposed within and contacts one opening.02-05-2009

Gerald R. Williams, Philadelphia, PA US

Patent application numberDescriptionPublished
20120130505Punch, Implant and Associated Method - A kit for use in performing joint arthroplasty on a head of a long bone is disclosed. The kit includes: a first implant including a first implant articulating surface and an opposed first implant mounting surface having a first implant location feature; and an instrument for preparing a cavity in the head of the long bone. The instrument includes a body and a punch extending from the body. The punch includes a portion thereof having a shape similar to the first implant location surface of the implant. A method for providing joint arthroplasty is also disclosed.05-24-2012

Gerald R. Williams, Villanova, PA US

Patent application numberDescriptionPublished
20110282158SPREADING RETRACTOR - A spreadable retractor for use in joint arthroplasty. The retractor includes a first arm having a first portion and a second portion that is movably coupled to the first portion. The second portion is also coupled to a first retaining member that is sized and shaped to retain a portion of a coracoid process. A second arm is also included in the retractor and is movably coupled to the first arm. The second arm has a first portion and a second portion that is movably coupled to the first portion. Also, the second portion is coupled to a second retaining member that is sized and shaped to couple to a resected humerus.11-17-2011

Gerald Ross Williams, Villanova, PA US

Patent application numberDescriptionPublished
20100070044Concave Resurfacing Prosthesis - A glenoid component for use with a prosthetic humeral component for use in performing shoulder arthroplasty is provided. The glenoid component may be fitted at least partially into a cavity formed in the glenoid vault. The glenoid component includes a body having a stem portion for inserting at least partially into the cavity formed in the glenoid vault. The stem portion cooperates with the interior wall of the cavity formed in the glenoid vault. The body has a bearing portion for articulating cooperation with the prosthetic humeral component.03-18-2010

Patent applications by Gerald Ross Williams, Villanova, PA US

Glenn Williams, Collegeville, PA US

Patent application numberDescriptionPublished
20130039470SAMPLE PLATE FOR AN X-RAY POWDER DIFFRACTION APPARATUS - A sample plate for use in an X-ray powder diffraction apparatus, the sample plate comprising a body having an exterior circumference which rotatable about a central axis, and a self contained rotating mechanism for rotating a sample holder containing a powder about a longitudinal axis, wherein the longitudinal axis intersects central axis; and wherein rotation about the central axis and rotation about the longitudinal axis occur simultaneously.02-14-2013

Harry Michael Williams, New Hope, PA US

Patent application numberDescriptionPublished
20120270014Method for Permanently Decorating Glass - A method for permanently decorating glass including the steps of applying ceramic colorants, which have a higher cure temperature than a glass workpiece, to the glass workpiece, placing the prepared glass workpiece on a textured carrier, heating the glass and carrier to about 1450 degree Fahrenheit followed by a cooling cycle, and removing the textured carrier from the glass workpiece. At about 1450 degree Fahrenheit, the higher cure temperature of the ceramic colorants causes them to sink or absorb into the softened glass workpiece and remain below its surface, resulting in a subcutaneous effect with a pleasing sense of depth. At the same time, preferably a desired texture is achieved in the workpiece as the softened glass deforms to the texture of the carrier on which it lays when heated and cooled.10-25-2012

James Matthew Williams, Latrobe, PA US

Patent application numberDescriptionPublished
20090258993Method of making a metal terephthalate polymer - A method of making a metal-terephthalate polymer from polyester ethylene terephthalate includes reacting polyester ethylene terephthalate with a metal compound in a non-aqueous melt environment at an elevated temperature. The elevated temperature will be greater than 270° C., and preferably rises to a temperature of about 520° C. The method is preferably carried out at a low pressure. The method may be used in the recycling of passenger vehicle tire shreds to produce a carbon black rich powder that is enriched in the metal-terephthalate polymer.10-15-2009

Jeffery J. Williams, Mckees Rocks, PA US

Patent application numberDescriptionPublished
20110144772PROCESS CONTROL AND OPTIMIZATION TECHNIQUE USING IMMUNOLOGICAL CONCEPTS - An integrated optimization and control technique performs process control and optimization using stochastic optimization similar to the manner in which biological immune systems work, and thus without the use of historical process models that must be created prior to placing the control and optimization routine in operation within a plant. An integrated optimization and control technique collects various indications of process control states during the on-line operation of the process, and attempts to optimize the process operation by developing a series of sets of process control inputs to be provided to the process, wherein the control inputs may be developed from the stored process control states using an objective function that defines a particular optimality criteria to be used in optimizing the operation of the process. The technique responds to a significant change in the current process state by determining anew set of process control inputs to be provided to the process based on one or more of the stored process control states.06-16-2011

Jeffrey L. Williams, Lebanon, PA US

Patent application numberDescriptionPublished
20090187097Electrocardiogram Reconstruction From Implanted Device Electrograms - A method of reconstruction of the standard 12-lead surface EKG given values of the electrical potential from an implanted medical device is described. This implanted device can be oriented in an arbitrary fashion and reconstruction technique is obtained through physical measurement of the orientation of the implanted device or correlation with a standard 12-lead EKG obtained from the patient.07-23-2009

Jesse David Williams, Hershey, PA US

Patent application numberDescriptionPublished
20090255360HEEL SHIFTER FOR A MOTORCYCLE - A gear shifter for a motorcycle having a rotatable shifter shaft. The gear shifter includes a shifter arm having a first portion and a second portion. The first portion of the shifter arm is configured to engage the shifter shaft. The gear shifter further includes a shifter peg movably coupled to the second portion of the shifter arm such that the shifter peg is pivotable with respect to the shifter arm between a first position and a second position. A retainer assembly is operable to selectively retain the shifter peg in each of the first and the second positions.10-15-2009

Jon Williams, Plymouth Meeting, PA US

Patent application numberDescriptionPublished
20080221075Therapeutic Uses For Aminosterol Compounds - A pharmaceutical composition includes, as an active ingredient, a compound according to formula 1436 as shown in FIG. 09-11-2008

Joshua Williams, Perkasie, PA US

Patent application numberDescriptionPublished
20120304140FULLY PARAMETERIZABLE REPRESENTATION OF A HIGHER LEVEL DESIGN ENTITY - A parameterizable design system is for use with semiconductor analog circuits and includes an interface unit connected to provide access to the system, a database unit connected to supply a library of parameterizable analog building blocks for a design entity, and a parameterization unit connected to select a parameter for one of the library of parameterizable analog building blocks to meet a design specification of the design entity. Additionally, the parameterizable design system may also include a simulation unit connected to simulate an operation of the design entity employing the parameter, and an analyzer unit connected to analyze a sensitivity of the parameter for the design entity based on the design specification. A method of designing a semiconductor analog circuit is also included.11-29-2012

J. Paul Williams, West Chester, PA US

Patent application numberDescriptionPublished
20080255862PREDICTIVE ASSET RANKING SCORE OF PROPERTY - The predictive asset ranking system and process quantifies the condition of major components and sub-components of a property based on a systematic comparison of one major component against another utilizing analytical hierarchy analysis. The predictive asset ranking may be expressed as a value or score that may be used as a benchmark to compare one property to another property. The predictive asset ranking process applies multiple analytical hierarchies to the various attributes of a property. The analytical hierarchy may be based on an attribute weighing process and may include a series of qualitative questions indicative of attributes of the property. The predictive asset ranking system may be dynamic and may be customized for the particular asset being evaluated. When the system is customized, the process may automatically recalculate the weights and redistribute the points used in the predictive asset ranking analysis.10-16-2008

Kevin J. Williams, Wynnewood, PA US

Patent application numberDescriptionPublished
20100155245Thrombospondin Fragments and Binding Agents in the Detection, Diagnosis and Evaluation of Cancer - The invention relates to thrombospondin fragments found in plasma, their use or use of portions thereof in diagnostic methods, as method calibrators, method indicators, and as immunogens, and as analytes for methods with substantial clinical utility; and their detection in plasma or other bodily fluids for purpose of diagnostic methods, especially for cancer.06-24-2010

Kevin Jon Williams, Wynnewood, PA US

Patent application numberDescriptionPublished
20110065206Thrombospondin Fragments and Uses Thereof in Clinical Assays for Cancer and Generation of Antibodies and Other Binding Agents - The invention relates to thrombospondin fragments found in plasma, their use or use of portions thereof in diagnostic methods, as method calibrators, method indicators, and as immunogens, and as analytes for methods with substantial clinical utility; and their detection in plasma or other bodily fluids for purpose of diagnostic methods, especially for cancer.03-17-2011

Kyle Williams, Shelocta, PA US

Patent application numberDescriptionPublished
20090148719FRICTION-STIR WELDMENTS AND SYSTEMS AND METHODS FOR PRODUCING THE SAME - Friction-stir weldments and systems and methods for producing the same are disclosed. In one embodiment, a metal product includes a first metal plate having a first center-neutral axis, a second metal plate comprising a second center-neutral axis, and a friction-stir corner weld that connects the first metal plate to the second metal plate, where the first center-neutral axis of the first metal plate is transverse to the second center-neutral axis of the second metal plate. In another embodiment, a system for producing friction-stir weldments includes a backup anvil having a first supporting face and a second supporting face, where the first supporting face is adapted to receive and support the first metal plate, and where the second supporting face is adapted to receive and support a second metal plate, wherein the center-neutral axis of the first metal plate is transverse to the center-neutral axis of the second metal plate.06-11-2009

Kyle L. Williams, Shelocta, PA US

Patent application numberDescriptionPublished
20100129683FUSION WELDABLE FILLER ALLOYS - Al—Mg and Al—Mg—Zn weld filler alloy compositions for use with fusion weldable 7xxx, 6xxx, 5xxx and 2xxx series aluminum alloy base metals are disclosed. The weld filler alloys may be used for joining a first aluminum base metal segment to a second aluminum base metal segment, where the base metal segments is at least one of 7xxx, 6xxx, 5xxx and 2xxx series aluminum alloy. The weld filler alloys, in wire or rod form, may also be used to repair a defective weld.05-27-2010
201002761087XXX WELD FILLER ALLOYS AND METHODS OF USING THE SAME - 7xxx aluminum alloy weld filler alloys and methods of using the same are described. The 7xxx aluminum alloy weld filler alloys may be used to repair 7xxx alloy products. The repaired volume of the 7xxx alloy products may be substantially crack-free, and may facilitate reuse of the repaired 7xxx alloy products.11-04-2010

Larry Jason Williams, Mount Joy, PA US

Patent application numberDescriptionPublished
20090252458OPTICAL ATTENUATOR - An attenuator connector comprising a housing having a front and rear orientation, a ferrule disposed in the housing, a clamping assembly disposed in the housing rearward of the ferrule and adapted to receive and retain a terminating fiber and a stub of attenuating fiber disposed in the ferrule.10-08-2009

Leroy C. Williams, Hellertown, PA US

Patent application numberDescriptionPublished
20110297512Conveyor Roller Servicing Apparatus - A conveyor belt support for a conveyor may comprise: a mandrel mountable to the far side of the conveyor and extending transversely toward the near side thereof; a member mountable to the mandrel from the near side of the conveyor that is slideable on and rotatable about the mandrel; and a roller supported by the member, wherein the roller is transverse to the conveyor belt when the member is mounted to the mandrel, wherein rotating the member in a first direction moves the roller to an operating position for supporting the conveyor belt and rotating the member in a second direction moves the roller to a position wherein the member and roller are removable from the support mandrel.12-08-2011

Lisa Z. Williams, Bernville, PA US

Patent application numberDescriptionPublished
20110226193ANIMAL GARMENT - A garment for animals includes a first panel of flexible material attachable to a second panel of flexible material, the first and second panels being connectable to each other by adjustable chest, body and tail fittings, such that the garment can be configured in situ to fit various sizes and shapes of animals, such as dogs. The garment is adapted to receive a disposable pad on an underside of the garment on the animal.09-22-2011

Mark A. Williams, Landenberg, PA US

Patent application numberDescriptionPublished
20120246798Windproof Waterproof Breathable Seamed Articles - The present invention provides waterproof, breathable non-textile seamed articles which exhibit high levels of durability and allow wearers a high level of flexibility and article strength. This invention is of particular interest for use in dexterous hand coverings and conformable foot coverings.10-04-2012

Mark Alan Williams, Landenberg, PA US

Patent application numberDescriptionPublished
20090208690Windproof Waterproof Breathable Seamed Articles - The present invention provides waterproof, breathable non-textile seamed articles which exhibit high levels of durability and allow wearers a high level of flexibility and article strength. This invention is of particular interest for use in dexterous hand coverings and conformable foot coverings.08-20-2009

Matthew F. Williams, Kingston, PA US

Patent application numberDescriptionPublished
20120314353HORIZONTAL PLATFORM AND ADVERTISEMENT DISPLAY APPARATUS AND METHOD OF USING SAME - A unique beverage holder is adapted to be mounted on a vertical wall surface, and includes a cantilevered beverage holder platform and an advertising display, preferably including a slot or other arrangement for receiving an advertising media and an outwardly facing window for viewing the advertisement. The device is preferably installed in bathrooms, and the like, such as above urinals to provide bathroom users with a place to set their beverage, and at the same time attracting attention to the advertisement while the user is captive. In one embodiment, the beverage holder is adapted to be reversibly mounted on a wall bracket such that the shelf unit may alternately be at the top or bottom of the device. The reversible beverage holder is preferably secured to the wall bracket by release tabs.12-13-2012

Matthew R. Williams, Lansdale, PA US

Patent application numberDescriptionPublished
20090126640APPARATUS AND SYSTEM FOR MONITORING THE INTAKE OF FOOD BY ANIMALS - An animal feeder comprising a hopper for storing pieces of food is provided. The hopper includes an opening and a gate movable with respect to the hopper between an open position rendering the opening at least partially accessible to an animal and a closed position at least partially preventing access to the opening by an animal. A switch is coupled for activation by movement of the gate.05-21-2009

Neil R. Williams, Lincoln University, PA US

Patent application numberDescriptionPublished
20110130756VASCULATURE DEVICE - A vasculature device with a wire with a shaped set portion, an electrically conductive path, an electrical connector connecting the wire to the electrically conductive path at a point distal to the shaped set portion, and a hypotube encasing the wire, electrically conductive path and electrical connector is provided. The vasculature device can be actuated from a low-profile configuration to a deployed configuration by heating of the wire, and in particular the shaped set portion of the wire, via application of an electrical current to the wire. The vasculature device is useful in removal of clots, thromboemboli and foreign bodies from the vasculature, and in particular the cerebral vasculature, and as steering wires or guidewires.06-02-2011

Peter D. Williams, Harleysville, PA US

Patent application numberDescriptionPublished
20090312335Hiv Integrase Inhibitors - Substituted hydroxytetrahydropyrrolopyrazinone and substituted hydroxytetrahydro-pyrazolopyrazinone compounds of Formula (I) are inhibitors of HIV integrase and inhibitors of HIV replication: (I) wherein R12-17-2009
201000565161-HYDROXY NAPHTHYRIDINE COMPOUNDS AS ANTI-HIV AGENTS - 1-Hydroxy naphthyridine compounds (e.g., 1-hydroxy naphthyridin-2(1H)-one compounds of Formula I are inhibitors of HIV integrase and/or HIV RNase H and inhibitors of HIV replication: (I) wherein X and R1-R6 are as defined herein. The compounds are useful in the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other anti-HIV agents such as HIV antivirals, immunomodulators, antibiotics and vaccines.03-04-2010
20100087419HIV INTEGRASE INHIBITORS - Compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication:04-08-2010
20120022045BRIDGED COMPOUNDS AS HIV INTEGRASE INHIBITORS - Compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: the asterisk * in Q denotes the point of attachment to the rest of the compound; and n, L1, L2, X01-26-2012

Patent applications by Peter D. Williams, Harleysville, PA US

Phillip Williams, State College, PA US

Patent application numberDescriptionPublished
20110042318SYSTEMS, METHODS AND COMPOSITIONS FOR THE SEPARATION AND RECOVERY OF HYDROCARBONS FROM PARTICULATE MATTER - Systems, methods and compositions for the separation and recovery of hydrocarbons from particulate matter are herein disclosed. According to one embodiment, a method includes contacting particulate matter with at least one ionic liquid. The particulate matter contains at least one hydrocarbon and at least one solid particulate. When the particulate matter is contacted with the ionic liquid, the hydrocarbon dissociates from the solid particulate to form a multiphase system.02-24-2011

Ralph A. Williams, Ridgway, PA US

Patent application numberDescriptionPublished
20120215628Chronostratigraphic Modeling and Mapping System and Method - A chronostratigraphic database comprising a plurality of discrete data points, wherein each data point comprises an x, y, z and T value, wherein x, y, and z are Cartesian coordinates describing a position and T is a geologic time event relative to said position; a method to produce a chronostratigraphic database and to utilize the database; and a modeling system wherein the database includes data formatted and arranged for use with a computer-implemented method or web-based method for controlling serving of an advertisement or public service message using its relevancy to a request.08-23-2012

Richard K. Williams, Gibsonia, PA US

Patent application numberDescriptionPublished
20090250522Method and Material for Manufacturing Electrically Conductive Patterns, Including Radio Frequency Identification (RFID) Antennas - A method of making an electrically conductive patterned film (10-08-2009

Richard T. Williams, Glenmoore, PA US

Patent application numberDescriptionPublished
20100243581Methods and means for economically assuring improved potable water quality management for aircraft and other applications - A potable water distribution system for use in aircraft, as well as potable water systems of boats, recreational vehicles/caravans, residential homes, dental offices, laboratories, vending machines, and the like, provides for sanitizing of the system without opening filter and/or purification units and removing filtering and/or purifying cartridges from the filter and/or purification units during the sanitizing process.09-30-2010
20110089092Apparatus for filtering and/or conditioning and/or purifying a fluid such as water - An apparatus for filtering water has an interface and a filtration/purification canister removably mountable thereon. Connecting the canister to the interface automatically opens a check valve in the interface to permit water to flow from the interface into and through the canister, and then back to and through the interface to an outlet port. Disconnecting the canister from the interface automatically closes the check valve, stopping the flow of water. An end cap may be substituted for the canister to permit fluid to flow through the interface when the canister is not mounted on the interface. The outlet port may be directly connected to an appliance that uses water, to eliminate possible contamination that may occur when water is brought indirectly form the outlet port to the appliance instead. A flapper valve is provided in the canister to prevent back flow of fluid from the inlet port of the canister when the canister is not mounted on the interface. The flapper valve also is provided with an actuating means to automatically open the flapper valve when the canister is mounted on the interface, which permits fluid to be drained from the canister when the fluid distribution system is being drained without disconnecting the canister from the interface.04-21-2011

Richard T. Williams, Uwchland, PA US

Patent application numberDescriptionPublished
20100170857Apparatus for filtering and/or conditioning and/or purifying a fluid such as water - An apparatus for filtering water has a valve head and a filtration/purification canister removably mountable thereon. Connecting the canister to the valve head automatically opens a check valve in the valve head to permit water to flow from the valve head into and through the canister, and then back to and through the valve head to an outlet port. Disconnecting the canister from the valve head automatically closes the check valve, stopping the flow of water. A bypass valve is provided in the valve head to permit a sanitizing solution to flow through the valve head and along the lines of the water distribution system to sanitize the system, while bypassing the canister. The outlet port may be directly connected to an appliance that uses water, to eliminate possible contamination that may occur when water is brought indirectly from the outlet port to the appliance instead.07-08-2010

Shannon Holly Williams, Newtown Square, PA US

Patent application numberDescriptionPublished
20100317261Chemical mechanical polishing pad having a low defect integral window - A chemical mechanical polishing pad having a polishing layer with an integral window and a polishing surface adapted for polishing a substrate selected from a magnetic substrate, an optical substrate and a semiconductor substrate, wherein the formulation of the integral window provides improved defectivity performance during polishing. Also provided is a method of polishing a substrate using the chemical mechanical polishing pad.12-16-2010
20120295442Chemical mechanical polishing pad having a low defect window - A chemical mechanical polishing pad having a polishing layer with an integral window and a polishing surface adapted for polishing a substrate selected from a magnetic substrate, an optical substrate and a semiconductor substrate, wherein the formulation of the integral window provides improved defectivity performance during polishing. Also provided is a method of polishing a substrate using the chemical mechanical polishing pad.11-22-2012

Shawn P. Williams, Pittsburgh, PA US

Patent application numberDescriptionPublished
20090023842PORPHYRIN AND CONDUCTIVE POLYMER COMPOSITIONS FOR USE IN SOLID-STATE ELECTRONIC DEVICES - Compositions comprising porphyrinic macrocycles and conjugated polymers such as polythiophene for use in organic electronic devices including solar cells are presented. Covalent linkage of a porphyrinic macrocycle to a polymer allows tuning of electronic and spectroscopic properties of conjugated polymers and can improve the heat stability of the system relative to a blended comparison. A composition comprising: at least one polymer comprising at least one porphyrinic macrocycle covalently linked to at least one conjugated polymer, wherein the porphyrinic macrocycle is metal-free is also presented. Inks can be formulated. Methods of making are provided.01-22-2009
20090155579ELECTROSTATIC COATINGS AND ARTICLES COMPRISING POLYTHIOPHENES - Electrostatic dissipation coatings based on regioregular polythiophenes including blends and block copolymers. The compositions can be soluble in organic solvents. Excellent film formation, transparency, stability, and conductivity control can be achieved.06-18-2009
20110095275ORGANIC ELECTRONIC DEVICES, COMPOSITIONS, AND METHODS - Organic electronic devices, compositions, and methods are disclosed that employ electrically conductive nanowires and conducting materials such as conjugated polymers such as sulfonated regioregular polythiophenes which provide high device performance such as good solar cell efficiency. Devices requiring transparent conductors that are resilient to physical stresses can be fabricated, with reduced corrosion problems.04-28-2011

Patent applications by Shawn P. Williams, Pittsburgh, PA US

Taffy J. Williams, Lansdale, PA US

Patent application numberDescriptionPublished
20100055032METHODS FOR VASCULAR IMAGING USING NANOPARTICULATE CONTRAST AGENTS - New and sensitive methods for imaging the perfusion of tissues and the extravasation of blood out vessels have been developed. The present invention is useful in the imaging of microperfusion in organ tissues (e.g., heart, liver, brain and kidneys) to aid in evaluating the perfusion status of organs on the level of the smallest blood vessels (i.e. capillaries). The present invention also provides methods and compositions for imaging and evaluating macrophages and plaque, e.g., vulnerable plaque. Such evaluations are important in a number of clinical diagnoses, including assessing organ damage associated with angina pectoris, heart attack, stroke, and the like, as well as assessing vessel leakages associated with aneurisms, diffuse bleedings after trauma, and the like.03-04-2010

Terry Michael Williams, Lower Gwynedd, PA US

Patent application numberDescriptionPublished
20080280792Stabilized Fluids - There is provided a fluid composition comprising 11-13-2008

Patent applications by Terry Michael Williams, Lower Gwynedd, PA US

Theresa Williams, Harleysville, PA US

Patent application numberDescriptionPublished
201200409982-ALKYL PIPERIDINE MGLUR5 RECEPTOR MODULATORS - The present invention is directed to 2-alkylpiperidines which are positive allosteric modulators of metabotropic glutamate receptors, particularly the mGluR5 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.02-16-2012

Theresa M. Williams, Harleysville, PA US

Patent application numberDescriptionPublished
20080280857CGRP receptor antagonists - The present invention is directed to compounds of Formula I:11-13-2008
20090131494Non-Nucleoside Reverse Transcriptase Inhibitors - Certain 1H-indole-2-carboxylates and -2-carboxamides are HIV reverse transcriptase inhibitors. These indole compounds and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.05-21-2009
20100113419CGRP RECEPTOR ANTAGONISTS - The present invention is directed to compounds of Formula I:05-06-2010
20100113421NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS - Compounds of Formula (I) are HIV reverse transcriptase inhibitors, wherein X, R05-06-2010
20100168097Non-Nucleoside Reverse Transcriptase Inhibitors - Compounds of Formula I: Formula (I); are HIV reverse transcriptase inhibitors, wherein R07-01-2010

Patent applications by Theresa M. Williams, Harleysville, PA US

Theresa M. Williams, Harelysville, PA US

Patent application numberDescriptionPublished
20090105228Heterocyclic benzodiazepine cgrp receptor antagonists - Compounds of formula I:04-23-2009

William V. Williams, Havertown, PA US

Patent application numberDescriptionPublished
20100113416JANUS KINASE INHIBITORS FOR TREATMENT OF DRY EYE AND OTHER EYE RELATED DISEASES - Methods, kits, and compositions for treating dry eye disorders and other related eye diseases are provided, wherein the methods, kits, and compositions utilize a JAK inhibitor.05-06-2010
20120301464JANUS KINASE INHIBITORS FOR TREATMENT OF DRY EYE AND OTHER EYE RELATED DISEASES - Methods, kits, and compositions for treating dry eye disorders and other related eye diseases are provided, wherein the methods, kits, and compositions utilize a JAK inhibitor.11-29-2012

Patent applications by William V. Williams, Havertown, PA US