Wiggin
Douglas Malcolm Wiggin, Burnaby CA
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20150036204 | OPTICAL FILTER WITH LIGHT SOURCE - An apparatus comprising a switchable optical filter comprising a layer of switchable material, the switchable material comprising a photochromic/thermochromic, a photochromic/photochromic, or a photochromic/electrochromic compound; a first light source providing light of a wavelength that causes the switchable material to transition from a faded state to a dark state, or a dark state to a faded state; and a switch for controlling activation of the first light source | 02-05-2015 |
Matthew Wiggin, Los Altos, CA US
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20130296176 | BIOMARKER ANAYLSIS USING SCODAPHORESIS - The invention discloses methods and apparatus for characterizing trace nucleic acids that are biomarkers for disease. The methods and apparatus provide increased sensitivity to such trace nucleic acids, and allow analysis of nucleic acids present in a sample at only 0.01% of the wild-type sequences. The methods and apparatus are also designed for straightforward multiplexing, thus allowing pooling of clinical samples. | 11-07-2013 |
Matthew Wiggin, Vancouver CA
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20160002717 | DETERMINING MUTATION BURDEN IN CIRCULATING CELL-FREE NUCLEIC ACID AND ASSOCIATED RISK OF DISEASE - The invention generally relates to methods of assessing an individual's risk of developing a disease associated with accumulation of DNA mutations by determining the mutation burden in their circulating cell-free nucleic acid relative to a reference sequence. The invention further relates to establishing a score indicative of the individual's risk by assessing the individual's mutation burden against a mutation burden continuum containing various thresholds associated with different degrees of risk. The reference sequence and the continuum may be constructed from a variety of sources. In certain aspects, methods of the invention relate to compilation of a database of mutation burdens for individuals along with population characteristics for each individual. | 01-07-2016 |
Michael Bruce Wiggin, Raleigh, NC US
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20130296741 | ANKLE-FOOT ORTHOTIC DEVICES WITH INTEGRATED VIBROTACTILE BIOFEEDBACK AND RELATED METHODS - Ankle-foot orthotic devices with integrated vibrotactile biofeedback and related methods are disclosed. According to an aspect, an ankle-foot orthotic device may include one or more sensors configured to determine a gait phase of a user and to determine a movement of the user. Further, the device may include a controller configured to communicate feedback to the user based on the determined gait phase and the determined movement of the user. | 11-07-2013 |
Robert Wiggin, Middletown, CT US
Patent application number | Description | Published |
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20100158457 | RUGGEDIZED, LIGHTWEIGHT, AND COMPACT FIBER OPTIC CABLE - A fiber optic cable is described. The fiber optic cable includes optical fibers, a matrix substantially encasing the optical fibers, a tape substantially around the matrix, a tube substantially around the tape, a strength member around the tube, and a jacket substantially on an outer periphery of the fiber optic cable. | 06-24-2010 |