Patent application number | Description | Published |
20080272254 | Medical Device Safety Support with Infinite Positioning - A medical device safety support apparatus features a clamp member configured to be attached to an IV pole, a bed rail, or other support structure. A medical device support member extends from the clamp member and is configured to support a cooperatively configured medical device. The medical device support member may include a socket which receives a post that extends from the medical device, and a lockdown member having a set-screw portion and a handle is provided to secure the post within the socket. The post has a circumferential channel in which the set-screw portion seats, thereby allowing the post to be retained within the socket when the lockdown member is loosened so as to prevent the medical device from being removed from the support member. | 11-06-2008 |
20100056994 | PUMPING APPARATUS WITH SECURE LOADING FEATURES - A pumping apparatus and pump set for use to deliver a supply of liquid to a patient. The feeding set has a conduit for the nutrient liquid and a safety interlock device associated with the conduit. The pumping apparatus has a pumping device and a control system for controlling operation of the pump. An electromagnetic radiation source is operatively connected to the control system of the pump for emitting an electromagnetic radiation signal in a direction for striking the safety interlock device of the feeding set. The safety interlock device being adapted to affect the direction of the electromagnetic radiation. An electromagnetic radiation detector is operatively connected to the control system for receiving the electromagnetic radiation signal when the direction is affected by the safety interlock device, and provides an indication to the control system that the feeding set conduit is properly positioned in the feeding pump. | 03-04-2010 |
20100063463 | CANISTER MEMBRANE FOR WOUND THERAPY SYSTEM - A portable system for subatmospheric pressure therapy in connection with healing a surgical wound includes a wound dressing dimensioned for positioning relative to a wound bed of a subject and a collection canister in fluid communication with the wound dressing. The canister includes a first vacuum chamber for drawing a vacuum and a second fluid chamber for collecting fluids removed from the wound dressing under the vacuum. The vacuum chamber may have a vacuum and a power source. The canister further includes a hydrophobic membrane separating the first and the second fluid vacuum chambers. The hydrophobic membrane is dimensioned to span a major portion of the cross-sectional area of the canister. The hydrophobic membrane may be dimensioned to substantially span an internal dimension of the collection canister. The hydrophobic membrane may include one or more outwardly extending lobes. The outwardly extending lobes may be arranged in staggered relation. The hydrophobic membrane may be releasably mountable to the canister, and, may be supported within a divider separating the first vacuum chamber and the second fluid chamber. | 03-11-2010 |
20100198144 | METHOD FOR USING A PUMP SET HAVING SECURE LOADING FEATURES - A controller for operating a pumping apparatus to supply fluid to a patient through a pump set includes a processor programmed to instruct a first source of electromagnetic radiation to emit electromagnetic radiation in a direction for striking a safety interlock of the pump set. The processor activates a first electromagnetic radiation detector to detect the electromagnetic radiation emitted from the first source. The processor instructs a second source of electromagnetic radiation to emit electromagnetic radiation in a direction for striking the safety interlock. The processor activates a second electromagnetic radiation detector to detect the electromagnetic radiation emitted from the second source. The processor controls the pumping apparatus to operate for pumping fluid in the pump set only when electromagnetic radiation emitted from the first source is detected by the first detector and when the electromagnetic radiation emitted from the second source is not detect by the second detector. | 08-05-2010 |
20100198145 | PUMP SET WITH SAFETY INTERLOCK - A safety interlock for use in a medical device includes a central tubular portion defining a fluid passage for passing fluid through the safety interlock. An outer ring portion is adapted for mounting on the medical device. The outer ring portion is formed of a light transmitting material and includes at least one interposing surface. A connector portion connects the central tubular portion to the outer ring portion so that the outer ring portion is spaced radially outwardly from the central tubular portion in opposed relation with at least a portion of the central tubular portion. The safety interlock device is adapted for mounting in medical device in a path of electromagnetic radiation from a source of electromagnetic radiation for reflecting the electromagnetic radiation to a electromagnetic radiation detector when properly loaded on the medical device. | 08-05-2010 |
20110021979 | Enteral Feeding Set and Interlock Device Therefor - An enteral feeding set for an enteral feeding pump having a control system for controlling operation of the pump to supply nutrient liquid to a patient through the enteral feeding set loaded in the pump, a source of electromagnetic radiation for emitting electromagnetic radiation and an electromagnetic radiation detector for receiving the electromagnetic radiation. The enteral feeding set includes a conduit for carrying nutrient liquid to a patient and a safety interlock device associated with the conduit adapted for mounting in the pump. The safety interlock device includes an electromagnetic radiation propagation affecting member formed to affect the propagation of electromagnetic radiation from the source of electromagnetic radiation through the safety interlock device and block visible light when properly loaded on the pump for directing the electromagnetic radiation from the source of electromagnetic radiation to the detector. | 01-27-2011 |
20110251518 | Obturator with Safety Shield - An obturator for use with a needle assembly to remove a sample of biological material collected in a hollow needle of the needle assembly includes a grip for holding and manipulating the obturator. A shaft extending from the grip is sized and shaped for reception in a central axial passageway of the needle assembly for pushing the sample out of the central axial passageway. A shield is slidably supported on the shaft for engaging and shielding a sharp end of the hollow needle when the obturator shaft is being inserted into the needle to remove the sample. | 10-13-2011 |
20120172801 | Safety Interlock - A safety interlock for use in a medical device having a control system for controlling operation of the medical device includes a central tubular portion defining a fluid passage for passing fluid through the safety interlock. An outer ring portion is adapted for mounting the safety interlock in the medical device. A spoked connector portion connects the central tubular portion to the outer ring portion so that the outer ring portion is spaced radially outwardly from the central tubular portion in opposed relation with at least a portion of the central tubular portion. The safety interlock is adapted for mounting in the medical device in a path of electromagnetic radiation from a source of electromagnetic radiation such that the central tubular portion reflects the electromagnetic radiation to a electromagnetic radiation detector when properly loaded on the medical device. | 07-05-2012 |
20120182143 | Wireless Relay Module For Remote Monitoring Systems Having Power And Medical Device Proximity Monitoring Functionality - Wireless relay modules for networked communications between a medical device and a remote monitoring device via wireless relay networks and/or internet-accessible wireless communications networks. The wireless relay module includes a receiver, a first transmitter coupled to the wireless relay network, a second transmitter coupled to the internet-accessible wireless communication network, a controller and a display. The controller is coupled to the first and second transmitters, and controls the wireless relay module to select one of the transmitters for transmitting medical device data over one of the two respective networks. The controller generates an alarm signal and stores storing wirelessly-received medical device data in a memory of the wireless relay module upon detecting a changed characteristic for a power source of the wireless relay module. The controller also generates an alarm upon detecting a change in a characteristic of a signal transmitted by the medical device. | 07-19-2012 |
20120182894 | WIRELESS RELAY MODULE FOR REMOTE MONITORING SYSTEMS - A wireless relay module for networked communications between a series of medical devices and a remote monitoring device. The relay module communicates with the remote monitoring device over one or more internet-accessible wireless communication networks, and includes a receiver, transmitter for communicating over wireless relay networks, other transmitters for the one or more internet-accessible wireless communications networks; and a controller. The controller determines a status of the one or more internet-accessible wireless communications networks. When the status indicates that at least one of the interne-accessible wireless communications network is available, the appropriate transmitter is selected for the transmitting medical device data over the available internet-accessible wireless communications networks. When internet-accessible wireless communications networks are not accessible, the appropriate wireless relay network transmitter is selected for transmitting the data to another wireless relay module. | 07-19-2012 |
20120182924 | Medical Device Wireless Network Architectures - An architecture for networked communications between a series of medical devices and a remote monitoring device. An interface circuit coupled to each medical device communicates with one of a plurality of relay modules via a wireless relay network. The relay modules communicate with the remote monitoring device over an internet-accessible wireless communication network. Each relay module includes a receiver coupled to the wireless relay network, a first transmitter coupled to the wireless relay network, a second transmitter coupled to the internet-accessible wireless communications network; and a controller. The controller determines a status of the internet-accessible wireless communications network. When the status indicates that the internet-accessible wireless communications network is accessible to the wireless relay module, the second transmitter is selected for transmitting medical device data. When the internet-accessible wireless communications network is not accessible, the first transmitter is selected for transmitting the data to another wireless relay module. | 07-19-2012 |
20120182927 | Wireless Relay Module For Monitoring Network Status - A wireless relay module for networked communications between a series of medical devices and a remote monitoring device. An interface circuit coupled to each medical device communicates with the wireless relay module via a wireless relay network. The relay module communicates with the remote monitoring device over an internet-accessible wireless communication network. The controller determines a status of the networks. When the status indicates that the internet-accessible wireless communications network is available, a transmitter transmits medical device data over this network. When the internet-accessible wireless communications network is not accessible, another transmitter transmits the data to another wireless relay module. In addition, the controller obtains status information the two networks, and either transmits this information to one of the medical devices or prepares the information for display on a display of the wireless relay module. | 07-19-2012 |
20120184207 | Wireless Relay Module for Remote Monitoring Systems - A wireless relay module for networked communications between a series of medical devices and a remote monitoring device. An interface circuit coupled to each medical device communicates with the wireless relay module via a wireless relay network. The relay module communicates with the remote monitoring device over an internet-accessible wireless communication network, and includes a receiver coupled to the wireless relay network, a first transmitter coupled to the wireless relay network, a second transmitter coupled to the internet-accessible wireless communications network; and a controller. The controller determines a status of the internet-accessible wireless communications network. When the status indicates that the internet-accessible wireless communications network is accessible, the second transmitter is selected for transmitting medical device data. When the internet-accessible wireless communications network is not accessible, the first transmitter is selected for transmitting the data to another wireless relay module. | 07-19-2012 |
20120184899 | PUMP SET HAVING SECURE LOADING FEATURES - An enteral feeding set for an enteral feeding pump having a control system for controlling operation of the pump to supply nutrient liquid to a patient through the enteral feeding set loaded in the pump, a source of electromagnetic radiation operatively connected to the control system of the pump for emitting electromagnetic radiation, and an electromagnetic radiation detector operatively connected to the control system for receiving the electromagnetic radiation and providing an indication to the control system that the feeding set is properly loaded in the pump. The feeding set includes a conduit for carrying nutrient liquid to a patient. A safety interlock includes a light pipe for providing a passage of the electromagnetic radiation from the source of electromagnetic radiation to the electromagnetic radiation detector only when the safety interlock is loaded in the pump such that nutrient liquid flow to the patient is regulated by the pump. | 07-19-2012 |
20120185268 | System And Method For Patient Identification In A Remote Monitoring System - A patient monitoring system for remote monitoring of medical devices. The system includes a medical device, a patient identification device and a wireless relay module. The relay module receives patient identification information from the patient identification device and medical device identification from the medical device via a wireless relay network, and transmits this information to the remote monitoring device via an internet-accessible wireless communications network. The remote monitoring device returns an acknowledgement status to the relay module, which the relay module transmits to the medical device. Upon receipt of an acknowledgment status indicating that the patient's use of the medical device is authorized, the medical device transmits medical device data to the relay module via the wireless relay network, and the relay module relays the medical device data to the remote monitoring device via the internet-accessible wireless communications network. | 07-19-2012 |
20120226768 | Remote Monitoring Systems for Monitoring Medical Devices Via Wireless Communication Networks - A remote monitoring system for monitoring a plurality of medical devices at a patient care or home care facility. The system includes a device integration server in communication with wireless relay modules for receiving data packets from the medical devices including an identifier and data for each medical device. The system also includes a data management system and an outbound web server. The data management system is configured to log data for the medical devices. The web server is configured to provide webpages including the data of the medical devices for display on a remote monitoring computer, subject to authentication of an associated data request from the monitoring computer. The Web server is configurable to look up patient information from a secure source when user has appropriate permissions. In addition, the device integration server is configured to process alert messages received from the wireless relay modules and, in response, to transmit text message information to the wireless relay modules to be relayed to one or more text messaging recipients. | 09-06-2012 |
20120226771 | Remote Monitoring Systems And Methods For Medical Devices - A remote monitoring system for monitoring a plurality of medical devices at a patient care or home care facility. The system includes a device integration server in communication with wireless relay modules for receiving data packets from the medical devices including an identifier and data for each medical device. The system also includes an outbound web server. The web server is configured to provide webpages including the data of the medical devices for display on first and second remote monitoring devices, subject to authentication of an associated data request from the monitoring device. | 09-06-2012 |
20120265160 | Canister For Wound Therapy And Related Methods Therefor - A portable system for subatmospheric pressure therapy in connection with healing a surgical wound includes a wound dressing dimensioned for positioning relative to a wound bed and a collection canister in fluid communication with the wound dressing. The canister includes a first vacuum chamber for drawing a vacuum and a second fluid chamber for collecting fluids removed from the wound dressing under the vacuum. The canister further includes a hydrophobic membrane separating the first and second chambers. The hydrophobic membrane is dimensioned to span a major portion of the cross-sectional area of the canister. The hydrophobic membrane may be dimensioned to substantially span an internal dimension of the collection canister. The hydrophobic membrane may include one or more outwardly extending lobes. The hydrophobic membrane may be releasably mountable to the canister, and, may be supported within a divider separating the first vacuum chamber and the second fluid chamber. | 10-18-2012 |
20130162426 | Wireless Relay Module For Remote Monitoring Systems Having Alarm And Display Functionality - Wireless relay modules for enabling alarm recognition and alerts in networked communications between a series of medical devices and a remote monitoring device via wireless relay networks and/or internet-accessible wireless communications networks. The wireless relay module including a receiver, a first transmitter coupled to the wireless relay network, a second transmitter coupled to the internet-accessible wireless communication network, a controller and a display. The controller identifying if received medical device data from the medical device includes an alarm condition and causing the display to display an alert accordingly. The wireless relay module may additionally include a speaker alone or in combination with a microphone for providing an audible alert of the alarm condition and verbal communication between a local healthcare provider and a clinician at the remote monitoring device. | 06-27-2013 |
20140100523 | PUMP SET HAVING SECURE LOADING FEATURES - An enteral feeding set for an enteral feeding pump having a control system for controlling operation of the pump to supply nutrient liquid to a patient through the enteral feeding set loaded in the pump, a source of electromagnetic radiation operatively connected to the control system of the pump for emitting electromagnetic radiation, and an electromagnetic radiation detector operatively connected to the control system for receiving the electromagnetic radiation and providing an indication to the control system that the feeding set is properly loaded in the pump. The feeding set includes a conduit for carrying nutrient liquid to a patient. A safety interlock includes a light pipe for providing a passage of the electromagnetic radiation from the source of electromagnetic radiation to the electromagnetic radiation detector only when the safety interlock is loaded in the pump such that nutrient liquid flow to the patient is regulated by the pump. | 04-10-2014 |
20140135731 | Feeding Set with Cassette and Related Methods Therefor - A pump set for use with a pumping apparatus having a rotor with a plurality of rollers mounted on the rotor rotatable about an axis of rotation is disclosed. The pump set comprises a cassette body comprising a stator member with a fixed portion secured to the cassette body, a second portion opposite the fixed portion, a reaction surface and a second surface opposite the reaction surface, the reaction surface defined between the fixed portion and the second portion, and a tube secured to the cassette body, at least a portion of the tube is disposed against the reaction surface. | 05-15-2014 |
20140152466 | REMOTE MONITORING SYSTEMS FOR MONITORING MEDICAL DEVICES VIA WIRELESS COMMUNICATION NETWORKS - A remote monitoring system for monitoring a plurality of medical devices at a patient care or home care facility. The system includes a device integration server in communication with wireless relay modules for receiving data packets from the medical devices including an identifier and data for each medical device. The system also includes a data management system and an outbound web server. The data management system is configured to log data for the medical devices. The web server is configured to provide webpages including the data of the medical devices for display on a remote monitoring computer, subject to authentication of an associated data request from the monitoring computer. The Web server is configurable to look up patient information from a secure source when user has appropriate permissions. In addition, the device integration server is configured to process alert messages received from the wireless relay modules and, in response, to transmit text message information to the wireless relay modules to be relayed to one or more text messaging recipients. | 06-05-2014 |
20150070187 | Wireless Relay Module For Remote Monitoring Systems - Systems and methods for communication include one or more wireless relay devices having a first receiver capable of wirelessly receiving medical device data over a wireless relay network from at least one network device, a first transmitter capable of wirelessly transmitting data over an internet-accessible wireless communications network and a second transmitter capable of wirelessly transmitting medical device data to a second medical device or a wireless relay module over the wireless relay network. Patient identification information can be obtained and/or communicated. | 03-12-2015 |
20150090849 | MEDICAL DEVICE SUPPORTING APPARATUS - A medical device support apparatus for use in a medical environment to releasably secure a medical device to a support structure, the medical device support apparatus having a base member configured to releasably mount the medical device support apparatus on the support structure; and a medical device mounting assembly including a base attachment portion and a device attachment portion connected to the base attachment portion, and further including a connection mechanism mounting the base attachment portion on the base member for rotation about a roll axis relative to the base member whereby the medical device mounting assembly can hold the medical device at different selected angles about the roll axis with respect to the base member, the device attachment portion being constructed for translational, sliding reception of the medical device into mounting engagement with the device attachment portion. | 04-02-2015 |
Patent application number | Description | Published |
20090032253 | Composition and Method For Making A Proppant - The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants. | 02-05-2009 |
20090032254 | Composition and Method For Making A Proppant - The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants. | 02-05-2009 |
20090038798 | Composition and Method For Making A Proppant - The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants. | 02-12-2009 |
20090065208 | Composition and Method For Making A Proppant - The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants. | 03-12-2009 |
20090137433 | Composition And Method For Making A Proppant - The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants. | 05-28-2009 |
20110077176 | Composition And Method For Making A Proppant - The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants. | 03-31-2011 |
20150224450 | ELECTRICALLY CONDUCTING REVERSE OSMOSIS MEMBRANES - The disclosure provides composite membranes for use in water purification and filtration. | 08-13-2015 |
Patent application number | Description | Published |
20080223302 | Animal Litter, Process for Preparing Animal Litter, and Method of Removal of Animal Waste - Disclosed are an animal litter, a process for preparing the animal litter, and a method for removal of animal waste. The method for removal of animal waste comprises providing a copra residue, such as copra cake or copra oil cake, allowing an animal to excrete waste into the litter, and removing at least a portion of the soiled litter. An animal litter in accordance with the disclosed teachings includes a copra residue in combination with one or more absorbent materials, such as clay, whole ground grain, spent grain germ, or any other absorbent material. The process for preparing the animal litter comprises blending copra residue with one or more absorbent materials. The animal litters disclosed herein may include other ingredients, such as additional absorbent materials, preservatives, and so forth. | 09-18-2008 |
20130213309 | Animal Litter, Process for Preparing Animal Litter and Method of Removal of Animal Waste - An animal litter, process for preparing the animal litter and a method for removal of animal waste using the animal litter are provided. The animal litter generally includes ground malt sprouts, a lubricant, and a cohesiveness agent. The animal litter is in the form of discrete plural particles which tend to agglomerate when wetted. | 08-22-2013 |
20130213312 | Animal Litter, Process for Preparing Animal Litter and Method of Removal of Animal Waste - An animal litter, process for preparing the animal litter and a method for removal of animal waste using the animal litter are provided. The animal litter generally includes corn cob, a lubricant, and a cohesiveness agent. The animal litter is in the form of discrete plural particles which tend to agglomerate when wetted. | 08-22-2013 |
20130213313 | Animal Litter, Process for Preparing Animal Litter and Method of Removal of Animal Waste - An animal litter, process for preparing the animal litter and a method for removal of animal waste using the animal litter are provided. The animal litter generally includes at least about 10 weight % finely ground pine wood powder. Further the animal litter includes a lubricant and a cohesiveness agent. The animal litter is in the form of discrete plural particles which tend to agglomerate when wetted. | 08-22-2013 |
20130213314 | Odor-Absorbing Materials and Processes for Their Preparation and Use - A slightly puffed, low density, moisture-absorbing and odor-absorbing additive that can readily remove undesirable odors from a confined space is produced from re-purposed spent carbon materials obtained from other processes. The product is particularly suitable as an addition to animal litters and the like with possible uses in human applications. An aspect of the method includes a step of extruding a spent carbon mixture, optionally containing diatomaceous earth to obtain the additive. Also disclosed are de-germinated corn flour, or grits, that aid process flow and can serve as a substrate for the spent carbon materials. | 08-22-2013 |
20150136036 | Odor-Absorbing Materials and Processes for Their Preparation and Use - A slightly puffed, low density, moisture-adsorbing and odor-absorbing additive that can readily remove undesirable odors from a confined space is produced from re-purposed spent carbon materials obtained from other processes. The product is particularly suitable as an addition to animal litters and the like with possible uses in human applications. An aspect of the method includes a step of extruding a spent carbon mixture, optionally containing diatomaceous earth to obtain the additive. Also disclosed are de-germinated corn flour, of grits, that aid process flow and can serve as a substrate for the spent carbon materials. | 05-21-2015 |
20160081296 | Animal Litter, Process for Preparing Animal Litter and Method of Removal of Animal Waste - An animal litter, process for preparing the animal litter and a method for removal of animal waste using the animal litter are provided. The animal litter generally includes corn cob, a lubricant, and a cohesiveness agent. The animal litter is in the form of discrete plural particles which tend to agglomerate when wetted. | 03-24-2016 |
20160081297 | Animal Litter, Process for Preparing Animal Litter and Method of Removal of Animal Waste - An animal litter, process for preparing the animal litter and a method for removal of animal waste using the animal litter are provided. The animal litter generally includes at least about 10 weight % finely ground pine wood powder. Further the animal litter includes a lubricant and a cohesiveness agent. The animal litter is in the form of discrete plural particles which tend to agglomerate when wetted. | 03-24-2016 |
Patent application number | Description | Published |
20100035365 | Fluorescent Silica-Based Nanoparticles - The present invention provides nanoparticle compositions comprising, for example, a core comprising a fluorescent silane compound; and a silica shell on the core. Also provided are methods for the preparation of nanoparticle compositions including fluorescent nanoparticles, ligated-fluorescent nanoparticles, ligated-fluorescent nanoparticles having therapeutic agents, and ligated-fluorescent nanoparticles coupled or associated with an analyte. Also provided are methods: for the detection of the ligated-fluorescent nanoparticles; for associating the linked-fluorescent nanoparticles with a cellular component of interest and recording or monitoring the movement of the cellular component; for improving the therapeutic properties of the therapeutic agent by combining the therapeutic agent with linked-fluorescent nanoparticles and contacting or administering the combination to a cell or organism; for making and using the fluorescent nanoparticles in, for example, diagnostic agents for the detection of various analytes, and like applications. | 02-11-2010 |
20110027572 | THERMALLY STABLE CRYSTALLINE MESOPOROUS METAL OXIDES WITH SUBSTANTIALLY UNIFORM PORES - Highly crystalline metal oxide-carbon composites, as precursors to thermally stable mesoporous metal oxides, are coated with a layer of amorphous carbon. Using a ‘one-pot’ method, highly crystalline metal oxide-carbon composites are converted to thermally stable mesoporous metal oxides, having highly crystalline mesopore walls, without causing the concomitant collapse of the mesostructure. The ‘one-pot’ method uses block copolymers with an sp or sp2 hybridized carbon containing hydrophobic block as structure directing agents which converts to a sturdy, amorphous carbon material under appropriate heating conditions, providing an in-situ rigid support which maintains the pores of the oxides intact while crystallizing at temperatures as high as 1000 deg C. A highly crystalline metal oxide-carbon composite can be heated to produce a thermally stable mesoporous metal oxide consisting of a single polymorph. | 02-03-2011 |
20110028662 | PEG-COATED CORE-SHELL SILICA NANOPARTICLES AND METHODS OF MANUFACTURE AND USE - Described herein are PEG-coated, core-shell nanoparticles, which display reduced aggregation and/or reduced non-specific or undesired attachment characteristics. These fluorescent nanoparticle include: a silica-based core having an organic functional group that includes a mercapto substituent, an organic fluorescent compound, a silica shell; and a silane-PEG compound. The silica shell of the nanoparticle encapsulates the silica-based core and the silane-PEG compound is conjugated to the silica shell. | 02-03-2011 |
20110130478 | ORDERED POROUS MESOSTRUCTURED MATERIALS FROM NANOPARTICLE-BLOCK COPOLYMER SELF-ASSEMBLY - The invention provides mesostructured materials and methods of preparing mesostructured materials including metal-rich mesostructured nanoparticle-block copolymer hybrids, porous metal-nonmetal nanocomposite mesostructures, and ordered metal mesostructures with uniform pores. The nanoparticles can be metal, metal alloy, metal mixture, intermetallic, metal-carbon, metal-ceramic, semiconductor-carbon, semiconductor-ceramic, insulator-carbon or insulator-ceramic nanoparticles, or combinations thereof. A block copolymer/ligand-stabilized nanoparticle solution is cast, resulting in the formation of a metal-rich (or semiconductor-rich or insulator-rich) mesostructured nanoparticle-block copolymer hybrid. The hybrid is heated to an elevated temperature, resulting in the formation of an ordered porous nanocomposite mesostructure. A nonmetal component (e.g., carbon or ceramic) is then removed to produce an ordered mesostructure with ordered and large uniform pores. | 06-02-2011 |
20110263037 | POLYMERIC MATERIALS INCORPORATING CORE-SHELL SILICA NANOPARTICLES - Fibers, fabrics and textiles in which core-shell silica nanoparticles are incorporated are provided. The fibers, fabrics and textiles can be polymeric materials or natural cellulose-based or protein-based materials in which core-shell silica nanoparticles are incorporated. A variety of polymeric and natural materials can be employed, such as cellulose acetate, nylon, rayon, modacrylic, olefin, acrylic, polyester, polylactic acid, polylactic-co-glycolic acid (PLGA), polyurethane, aramid, wool, cotton, ramie, milk protein, soy protein, bamboo, etc. The core-shell silica nanoparticles can incorporate sensing, magnetic, thermal, electrical, chemical or RFID properties that can be imparted to the materials and that allow the materials to sense one or more conditions of interest, making them ideal for in situ sensing, treatment, or security applications. | 10-27-2011 |
20130039848 | FLUORESCENT SILICA-BASED NANOPARTICLES - The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as polyethylene glycol) (PEG) The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo The nanoparticle may further be conjugated to a ligand capable of binding to a cellular component associated with the specific cell type, such as a tumor marker A therapeutic agent may be attached to the nanoparticle Radionuclides/radiometals or paramagnetic ions may be conjugated to the nanoparticle to permit the nanoparticle to be detectable by various imaging techniques. | 02-14-2013 |
20130052421 | MONOCRYSTALLINE EPITAXIALLY ALIGNED NANOSTRUCTURES AND RELATED METHODS - A method for fabricating a nanostructure utilizes a templated monocrystalline substrate. The templated monocrystalline substrate is energetically (i.e., preferably thermally) treated, with an optional precleaning and an optional amorphous material layer located thereupon, to form a template structured monocrystalline substrate that includes the monocrystalline substrate with a plurality of epitaxially aligned contiguous monocrystalline pillars extending therefrom. The monocrystalline substrate and the plurality of epitaxially aligned contiguous monocrystalline pillars may comprise the same or different monocrystalline materials. The method provides the nanostructure where when the monocrystalline substrate and the plurality of epitaxial aligned contiguous monocrystalline pillars comprise different monocrystalline materials having a bulk crystal structure mismatch of up to about 10 percent, lattice mismatch induced crystal structure defects may be avoided interposed between the monocrystalline substrate and the plurality of epitaxially aligned contiguous monocrystalline pillars, which may have an irregular sidewall shape. | 02-28-2013 |
20130177934 | Aminated Mesoporous Silica Nanoparticles, Methods of Making Same, and Uses Thereof - A mesoporous silica particle having 10 mole % to 65 mole % amine groups present in the silica of the particle and on the silica surface of the particle. The particle has Pm | 07-11-2013 |
20140248210 | MULTIMODAL SILICA-BASED NANOPARTICLES - The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo. In order to target a specific cell type, the nanoparticle may further be conjugated to a ligand, which is capable of binding to a cellular component associated with the specific cell type, such as a tumor marker. In one embodiment, a therapeutic agent may be attached to the nanoparticle. To permit the nanoparticle to be detectable by not only optical fluorescence imaging, but also other imaging techniques, such as positron emission tomography (PET), single photon emission computed tomography (SPECT), computerized tomography (CT), bioluminescence imaging, and magnetic resonance imaging (MRI), radionuclides/radiometals or paramagnetic ions may be conjugated to the nanoparticle. | 09-04-2014 |
20150056471 | ORDERED POROUS NANOFIBERS, METHODS, AND APPLICATIONS - Described herein are nanofibers and methods for making nanofibers that have a plurality of pores. The pores have of any suitable size or shape. In some embodiments the pores are “mesopores”, having a diameter between 2 and 50 nm. In some embodiments, the pores are “ordered”, meaning that they have a substantially uniform shape, a substantially uniform size and/or are distributed substantially uniformly through the nanofiber. Ordering of the pores results in a high surface area and/or high specific surface area. Ordered pores, without limitation, result in a nanofiber that is substantially flexible and/or non-brittle. The nanofibers and methods for making nanofibers may be used, without limitation, in batteries, capacitors, electrodes, solar cells, catalysts, adsorbers, filters, membranes, sensors, fabrics and/or tissue regeneration matrixes. | 02-26-2015 |
20150182118 | SYSTEMS, METHODS, AND APPARATUS FOR MULTICHANNEL IMAGING OF FLUORESCENT SOURCES IN REAL TIME - Presented herein is a multichannel imaging system capable of detecting and distinguishing multiple fluorescent light sources simultaneously. Also described herein are methods of using the system to image disease or cellular abnormalities, e.g., for diagnostic and/or intraoperative purposes. | 07-02-2015 |
20150343091 | NANOPARTICLE DRUG CONJUGATES - Described herein are nanoparticle drug conjugates (NDCs), which, in certain embodiments, comprise a non-toxic, multi-modality, clinically proven silica-based nanoparticle platform with covalently attached drug molecules/moieties. The nanoparticle drug conjugates (NDCs) demonstrate imaging capability and targeting ligands which efficiently clear through the kidneys. Furthermore, the conjugates incorporate therapeutic agents for cancer detection, prevention, and/or treatment. | 12-03-2015 |
20150366995 | MESOPOROUS OXIDE NANOPARTICLES AND METHODS OF MAKING AND USING SAME - Mesoporous oxide nanoparticles, compositions comprising such nanoparticle, and methods of making and using such nanoparticles. The nanoparticles (e.g., compositions comprising the nanoparticles) have an average size of less than 15 nm and a narrow size distribution. The nanoparticles can be used in imaging applications and delivery of molecular cargo (e.g., a drug) to an individual. | 12-24-2015 |