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| 20080216232 | Patient Repositioning System - A patient positioning apparatus including a base, a support column, at least one positioning arm on the support column capable of being positioned over a bed and having a buckle and strap capable of securing to a patient support connected to bed linens or other flexible member so that a patient can be partially or totally suspended when an adjustable bed is lowered or when the patient support is raised. The apparatus may further include a telescoping support column and horizontal support for supporting positioning arms. Patient repositioning may be effectuated by positioning the arms over a patient, extending straps with buckle inserts into receiving buckles on a patient support or support bar secured to bed linens. A patient positioning apparatus may be free-standing or may be mounted to a ceiling or a wall or may include a swiveling support column. A fabric gripper with a support bar and an insert bar may be used to connect the bed linens or other flexible member to the apparatus. | 09-11-2008 |
| 20080301873 | Patient Positioning apparatus - Several embodiments of a patient positioning apparatus are disclosed, each configured for repositioning a patient on a bed. The apparatus includes a support frame which may be positioned over an adjustable bed so that the straps extend downwardly from the frame and secure to a patient support such as a support sheet so that a patient can be partially or totally suspended when the bed is lowered. | 12-11-2008 |
| 20100115695 | Dampened Belt Retractor - A patient positioning apparatus including at least one dampened belt retractor, a base, a support column, at least one positioning arm on the support column capable of being positioned over a bed and having a buckle and strap capable of securing to a patient support connected to bed linens or other flexible member so that a patient can be partially or totally suspended when an adjustable bed is lowered or when the patient support is raised. | 05-13-2010 |
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| 20080218184 | NANOPORE PLATFORMS FOR ION CHANNEL RECORDINGS AND SINGLE MOLECULE DETECTION AND ANALYSIS - Chemical modification of a glass and fused silica nanopore surfaces results in surface properties that are ideal for localized bilayer formation over a nanopore and subsequent ion channel recording. With no surface modification, one may form a bilayer supported on the glass capillary extending across the nanopore orifice. Changing the surface properties from that of bare glass to a moderately hydrophobic surface produces a lipid monolayer above the glass and spontaneously yields a bilayer across the nanopore orifice, effectively corralling a single protein ion channel in the lipid bilayer region spanning nanopore orifice. The bilayer structure over the modified nanopore is such that current can only flow through the protein ion channel. The protein ion channel is able to diffuse in the bilayer above the pore opening, but cannot leave this area to enter the lipid monolayer. The bilayer formed across the nanopore orifice exhibits high electrical breakdown voltage, is stable to mechanical vibrations, and is long lived. Resistance through the protein channel can be measured electrically and is exploited for stochastic single-molecule detection. Protein ion channels can be inserted and removed from the bilayer by adjusting transmembrane pressure, and adapter molecules can be electrostatically trapped in the ion channel by applying high transmembrane voltages. | 09-11-2008 |
| 20090175765 | Surfaces Resistant to Non-Specific Protein Adsorption and Methods of Producing the Same - A method of preventing non-specific adsorption of proteins onto a surface can include providing a substrate that has a surface on which surface groups are attached. A solution can be applied to the surface that includes a protective reagent having a terminal functional group exhibiting a dipole moment. A monolayer comprising the protective reagent is assembled on the surface by reacting the protective reagent with the surface groups, thereby creating a protected surface. The protective reagent alone is sufficient to confer to the protected surface an increased resistance to adsorption of proteins. | 07-09-2009 |
| 20100025263 | NANOPORE PARTICLE ANALYZER, METHOD OF PREPARATION AND USE THEREOF - Provided are the preparation, characterization, and application of a nanopore membrane device. The nanopore device comprises a thin membrane prepared from glass, fused silica, ceramics or quartz, containing one or more nanopores ranging from about 2 nm to about 500 nm. The nanopore is prepared by a template method using sharpened metal wires and the size of the pore opening can be controlled during fabrication by an electrical feedback circuit. The nanopore device is particularly useful for counting and analyzing nanoparticles of radius less than 400 nm. | 02-04-2010 |
| 20100038243 | NANOPORE BASED ION-SELECTIVE ELECTRODES - Nanopore based ion-selective electrodes and methods of their manufacture as well as methods for their use are disclosed and described. The nanopore based ion-selective electrode can include a pore being present in a solid material and having a nanosize opening in the solid material, a metal conductor disposed inside the pore opposite the opening in the solid material, a reference electrode material contacting said metal conductor and disposed inside the pore, a conductive composition in contact with the reference electrode and disposed in the pore, and an ion-selective membrane. The ion-selective membrane can be configured to isolate the metal conductor, reference electrode material, and conductive composition together within the pore. | 02-18-2010 |
| 20100320094 | Nanopore Platforms for Ion Channel Recordings and Single Molecule Detection and Analysis - A nanopore device includes a membrane having a nanopore extending there through forming a channel from a first side of the membrane to a second side of the membrane. The surface of the channel and first side of the membrane are modified with a hydrophobic coating. A first lipid monolayer is deposited on the first side of the membrane, and a second lipid monolayer is deposited on the second side of the membrane, wherein the hydrophobic coating causes spontaneous generation of a lipid bilayer across the nanopore orifice. Sensing entities, such as a protein ion channel, can be inserted and removed from the bilayer by adjusting transmembrane pressure, and adapter molecules can be electrostatically trapped in the ion channel by applying high transmembrane voltages, while resistance or current flow through the sensing entity can be measured electrically. | 12-23-2010 |
| 20110168551 | Nanopore Electrode, Nanopore Membrane, Methods of Preparation and Surface Modification, and Use Thereof - Provided are fabrication, characterization and application of a nanodisk electrode, a nanopore electrode and a nanopore membrane. These three nanostructures share common fabrication steps. In one embodiment, the fabrication of a disk electrode involves sealing a sharpened internal signal transduction element (“ISTE”) into a substrate, followed by polishing of the substrate until a nanometer-sized disk of the ISTE is exposed. The fabrication of a nanopore electrode is accomplished by etching the nanodisk electrode to create a pore in the substrate, with the remaining ISTE comprising the pore base. Complete removal of the ISTE yields a nanopore membrane, in which a conical shaped pore is embedded in a thin membrane of the substrate. | 07-14-2011 |
| 20110171518 | Three dimensional Battery Architectures and Methods of Making Same - A three-dimensional electrode structure for use in a battery comprising a porous three-dimensional substrate formed from a first electrically conductive material, an ion-conducting dielectric material disposed on the porous three dimensional substrate, and a second electrically conductive material disposed on the ion-conducting dielectric material, wherein the ion-conducting dielectric material separates the first electrically conductive material from the second electrically conductive material. | 07-14-2011 |
| 20120091005 | DETECTION OF NUCLEIC ACID LESIONS AND ADDUCTS USING NANOPORES - Methods, systems, and compounds for detecting modified nucleic acid bases are disclosed and described. The methods provide for detecting a nucleic acid lesion and can include directing a nucleic acid adduct into a channel, wherein the nucleic acid adduct includes a nucleic acid having a lesion and a current modulating compound coupled to the nucleic acid at the lesion ( | 04-19-2012 |
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| 20080244265 | MOBILITY DEVICE MANAGEMENT SERVER - A mobility device management server (MDMS) for use as part of a mobility device platform allowing for secure mobile computing is provided. In an illustrative implementation, an exemplary mobility device platform (MDP) comprises a mobility device (MD) operable to communicate with at least one computing environment through a communications interface and wherein the MD is operable to process and store secure web services, a communications network operable to communicate data and computing applications using web services, and a MDMS operable to generate, process, store, communicate and encrypt web services to the MD. Further, the MDMS is operable to perform one or more mobility device management functions to provide encryption keys to cooperating MDs and to authenticate and verify cooperating MDs requesting web services from the MDMS. The MDMS further may operate to perform metering functions and may operate to support intermittent connections between itself and cooperating MDs. | 10-02-2008 |
| 20080301443 | MOBILITY DEVICE PLATFORM - A mobility device platform allowing for secure mobile computing is provided. In an illustrative implementation, an exemplary mobility device platform comprises a mobility device operable to communicate with at least one computing environment through a communications interface and wherein the mobility device is operable to process and store secure web services, a communications network operable to communicate data and computing applications using web services, and a mobility device management server operable to generate, process, store, communicate and encrypt web services to the mobility device. Further, the mobility device management server is operable to perform one or more mobility device management functions to provide encryption keys to cooperating mobility devices and to authenticate and verify cooperating mobility devices requesting web services from the mobility device management server. The mobility device management server and mobility device may further operate to perform authentication and verification using user identification and password information. | 12-04-2008 |
| 20080301819 | MOBILITY DEVICE - A mobility device for use in a mobility device platform allowing for secure mobile computing is provided. In an illustrative implementation, an exemplary mobility device platform comprises a mobility device operable to communicate with at least one computing environment through a communications interface and wherein the mobility device is operable to process and store secure web services, a communications network operable to communicate data and computing applications using web services, and a mobility device management server operable to generate, process, store, communicate and encrypt web services to the mobility device. The mobility device may comprise a processing unit, a mobility device communications interface for interfacing with cooperating computing environments, a memory storage unit, and an operating system operable to execute web services and/or computing applications. | 12-04-2008 |
| 20090044259 | MOBILITY DEVICE PLATFORM PARADIGM - A mobility device platform allowing for secure mobile computing is provided. In an illustrative implementation, an exemplary mobility device platform comprises a mobility device operable to communicate with at least one computing environment through a communications interface and wherein the mobility device is operable to process and store secure web services, a communications network operable to communicate data and computing applications using web services, and a mobility device management server operable to generate, process, store, communicate and encrypt web services to the mobility device. Further, the mobility device management server is operable to perform one or more mobility device management functions to provide encryption keys to cooperating mobility devices and to authenticate and verify cooperating mobility devices requesting web services from the mobility device management server. The mobility device management server and mobility device may further operate to perform authentication and verification using user identification and password information. | 02-12-2009 |
| Patent application number | Description | Published |
|---|
| 20080218184 | NANOPORE PLATFORMS FOR ION CHANNEL RECORDINGS AND SINGLE MOLECULE DETECTION AND ANALYSIS - Chemical modification of a glass and fused silica nanopore surfaces results in surface properties that are ideal for localized bilayer formation over a nanopore and subsequent ion channel recording. With no surface modification, one may form a bilayer supported on the glass capillary extending across the nanopore orifice. Changing the surface properties from that of bare glass to a moderately hydrophobic surface produces a lipid monolayer above the glass and spontaneously yields a bilayer across the nanopore orifice, effectively corralling a single protein ion channel in the lipid bilayer region spanning nanopore orifice. The bilayer structure over the modified nanopore is such that current can only flow through the protein ion channel. The protein ion channel is able to diffuse in the bilayer above the pore opening, but cannot leave this area to enter the lipid monolayer. The bilayer formed across the nanopore orifice exhibits high electrical breakdown voltage, is stable to mechanical vibrations, and is long lived. Resistance through the protein channel can be measured electrically and is exploited for stochastic single-molecule detection. Protein ion channels can be inserted and removed from the bilayer by adjusting transmembrane pressure, and adapter molecules can be electrostatically trapped in the ion channel by applying high transmembrane voltages. | 09-11-2008 |
| 20100025263 | NANOPORE PARTICLE ANALYZER, METHOD OF PREPARATION AND USE THEREOF - Provided are the preparation, characterization, and application of a nanopore membrane device. The nanopore device comprises a thin membrane prepared from glass, fused silica, ceramics or quartz, containing one or more nanopores ranging from about 2 nm to about 500 nm. The nanopore is prepared by a template method using sharpened metal wires and the size of the pore opening can be controlled during fabrication by an electrical feedback circuit. The nanopore device is particularly useful for counting and analyzing nanoparticles of radius less than 400 nm. | 02-04-2010 |
| 20100320094 | Nanopore Platforms for Ion Channel Recordings and Single Molecule Detection and Analysis - A nanopore device includes a membrane having a nanopore extending there through forming a channel from a first side of the membrane to a second side of the membrane. The surface of the channel and first side of the membrane are modified with a hydrophobic coating. A first lipid monolayer is deposited on the first side of the membrane, and a second lipid monolayer is deposited on the second side of the membrane, wherein the hydrophobic coating causes spontaneous generation of a lipid bilayer across the nanopore orifice. Sensing entities, such as a protein ion channel, can be inserted and removed from the bilayer by adjusting transmembrane pressure, and adapter molecules can be electrostatically trapped in the ion channel by applying high transmembrane voltages, while resistance or current flow through the sensing entity can be measured electrically. | 12-23-2010 |
| 20110168551 | Nanopore Electrode, Nanopore Membrane, Methods of Preparation and Surface Modification, and Use Thereof - Provided are fabrication, characterization and application of a nanodisk electrode, a nanopore electrode and a nanopore membrane. These three nanostructures share common fabrication steps. In one embodiment, the fabrication of a disk electrode involves sealing a sharpened internal signal transduction element (“ISTE”) into a substrate, followed by polishing of the substrate until a nanometer-sized disk of the ISTE is exposed. The fabrication of a nanopore electrode is accomplished by etching the nanodisk electrode to create a pore in the substrate, with the remaining ISTE comprising the pore base. Complete removal of the ISTE yields a nanopore membrane, in which a conical shaped pore is embedded in a thin membrane of the substrate. | 07-14-2011 |
| Patent application number | Description | Published |
|---|
| 20090071098 | REINFORCED COMPOSITE PANEL - A reinforced panel, made of a composite material, includes a single base layer. A first plurality of mutually parallel ridges is affixed to the surface of the base layer. A second plurality of mutually parallel ridges is also affixed to the surface of the base layer, but oriented transverse to the first plurality. Structurally, the ridges and the base layer are co-cured to create an integral, continuous structure that provides stiffness and rigidity to the panel. | 03-19-2009 |
| 20090072088 | FLYAWAY KABOBS - An aircraft wing made of a composite material, and its method of manufacture, require a plurality of kabobs (i.e. substantially rectangular shaped hollow tubes having an open end and a closed end). Of these kabobs, several are aligned end-to-end, to create a section. Several sections are then positioned side-by-side and covered by a layer of composite material to define an aerodynamic surface for the wing. The juxtaposed sections also establish spar webs for the wing, and the closed ends of the juxtaposed sections establish transverse ribs for the wing. Thus, the kabobs form the main load-bearing member of the wing. The sections of composite material are co-cured with the composite material of the aerodynamic surface. | 03-19-2009 |
| 20090072429 | METHOD FOR MANUFACTURING A REINFORCED PANEL OF COMPOSITE MATERIAL - A method for manufacturing rigid panels made of a composite material requires a caul sheet having a smooth surface that is formed with a plurality of grooves. A first layer of the composite material is laid on the caul sheet, and is cut to create flaps that extend into the respective grooves. Strips of composite material are then placed along the edges of the groove to extend and overlap each other in the groove. Next, a unidirectional ply is placed along the length of the groove, and this combination is then covered with a second layer of the composite material. Together, the combination of the first and second layers, the strips and the unidirectional ply are co-cured to create a rigid panel with integral stiffening members. | 03-19-2009 |
