Patent application number | Description | Published |
20080241077 | BENZOYLGUANIDINE SALT AND HYDRATES THEREOF - 4-[4-(2-pyrrolylcarbonyl)-1-piperazinyl]-3-trifluoromethylbenzoylguanidine hydrochloride and its hydrates, processes for preparing this benzoylguanidine salt and its hydrates, pharmaceutical compositions containing this benzoylguanidine salt and its hydrates, and its use in treating diseases, particularly those in which inhibition of the cellular Na | 10-02-2008 |
20090209787 | METHOD OF PREPARING CHIRAL CYCLIC BETA-AMINOCARBOXAMIDES - The present invention encompasses a process for preparing compounds of formula (1), wherein a compound of general formula (2) is reacted in the presence of a catalyst and a solvent under hydrogen pressure to form a compound of general formula (1) and wherein A and R | 08-20-2009 |
20090298840 | Hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pterid- inyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament - Disclosed are hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, processes for preparing them and their use as pharmaceutical compositions. | 12-03-2009 |
20090318471 | New Salts and Crystalline Salt Forms of an Indolinone Derivative - The present invention relates to new salts and crystalline salt forms of an indolinone derivative which have valuable pharmacological properties, to a process for their manufacture, to pharmaceutical formulations containing them and to their use as medicament. | 12-24-2009 |
20100152439 | PRODUCTION METHOD - The present invention relates to a process for preparing compounds of general formula I | 06-17-2010 |
20110046395 | PROCESS FOR THE MANUFACTURE OF A 6-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE DERIVATIVE - The present invention relates to a process for the manufacture of the compound 4-[(Z)-[[4-[(dimethylamino)methyl]phenyl]amino](6-fluoro-1,2-dihydro-2-oxo-3H-in-dol-3-ylidene)methyl]-benzenepropanoic acid and to a new intermediate for the synthesis. | 02-24-2011 |
20110124859 | PROCESS FOR THE MANUFACTURING OF BETAMIMETICS - The present invention relates to a process for preparing betamimetics of formula 1, | 05-26-2011 |
20110130437 | SALT FORMS OF A 6-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE DERIVATIVE, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME - The present invention relates to salt forms of the compound 4-[(Z)-[[4-[(dimethylaminoJmethyllphenyllaminolCe-fluoro-1,2-dihydro2-oxo-3H-indol-3-ylidene)methyl]-benzenepropanoic acid which are suitable for pharmaceutical development and to a process for their manufacture. | 06-02-2011 |
20110201812 | PROCESS FOR THE MANUFACTURE OF AN INDOLINONE DERIVATIVE - The present invention relates to a process for the manufacture of a specific indolinone derivative and a pharmaceutically acceptable salt thereof, namely 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone and its monoethanesulfonate, to new manufacturing steps and to new intermediates of this process. | 08-18-2011 |
20110295000 | PRODUCTION METHOD - The present invention relates to a process for preparing compounds of general formula I | 12-01-2011 |
20120046284 | Salts and hydrates of 4-[(3-chloro-4-fluoro-phenyl)amino]-6-(cis-4--cyclohexan-1-yloxy)-7-metho- xy-quinazoline, their use as a medicament and the preparation thereof - The present invention relates to a compound of formula (I), | 02-23-2012 |