Wendel, US
Adam C. Wendel, New York, NY US
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20140266694 | Body Temperature Warning System - Methods and systems for avoiding undesired body temperatures in children, the elderly/infirm, and/or animals by transmitting one or more warning messages to one or more predetermined recipients so that corrective action can be taken. Using a child as an example, a wearable monitoring device is used to sense the presence of the child and to sense the body temperature of the child. When the monitoring device detects that it is being worn and that the sensed body temperature satisfies a threshold, the monitoring device transmits a warning message. | 09-18-2014 |
Andreas Wendel, Mountain View, CA US
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20160035223 | Traffic Signal Response for Autonomous Vehicles - Aspects of the disclosure relate to determining whether a vehicle should continue through an intersection. For example, the one or more of the vehicle's computers may identify a time when the traffic signal light will turn from yellow to red. The one or more computers may also estimate a location of a vehicle at the time when the traffic signal light will turn from yellow to red. A starting point of the intersection may be identified. Based on whether the estimated location of the vehicle is at least a threshold distance past the starting point at the time when the traffic signal light will turn from yellow to red, the computers can determine whether the vehicle should continue through the intersection. | 02-04-2016 |
Carol Lewis Wendel, Kula, HI US
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20090101184 | Spa filter cleaning device - A spa filter cartridge cleaning apparatus configured to substantially remove contaminants from a spa filter cartridge. The cleaning apparatus further includes a container that has a plurality of walls configured to define an interior volume of sufficient size to receive a spa filter cartridge therein. A cleaning cylinder is disposed within the container and functions to be mateably connected with the hollow core of a spa filter cartridge. The cleaning cylinder further includes a plurality of apertures that function to discharge cleaning liquid disposed within the cleaning cylinder. An attachment mechanism operably connects the cleaning cylinder to a water source. A pinion gear is operably connected to one end of the cleaning cylinder and functions to rotate the cleaning cylinder for increased cleaning effectiveness of the spa filter cartridge secured thereto. | 04-23-2009 |
Dale R. Wendel, Union, SC US
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20150192392 | Camouflage Pattern With Extended Infrared Reflectance Separation - Fabrics containing camouflage patterns are produced from dyes wherein at least certain of the colors contained in the pattern contain a low reflectance dye. The low reflectance dye is added to one or more colors in the pattern in order to preserve the camouflage pattern when viewed through night vision goggles as relatively long wavelengths, such at wavelengths greater than 900 nm. In one embodiment, the low reflectance dye comprises a thiazine. The low reflectance dye is blended with other dyes to produce colors in the pattern. By altering the concentration of the low reflectance dye in each of the colors, the colors contained in the camouflage pattern remain separate and distinct even at relatively long wavelengths. | 07-09-2015 |
Eric J. Wendel, Johnstown, CO US
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20100260024 | DISK-DRIVE SYSTEMS THAT MOVES DATA TO SPARE DRIVES FROM DRIVES ABOUT TO FAIL AND METHOD - A system and method for an improved multiple hard-disk-drive data-storage enclosure. Some embodiments position drives in counter-rotating pairs, each simultaneously accessing half the data, such that seek-caused actuator rotational-acceleration vibration cause simultaneous canceling rotational torque. Some embodiments position the edge of a first drive (or drive pair) at an angle to the actuator midpoint of a nearby second drive (or drive pair), such that rotational-acceleration vibration from a seek-caused actuator rotation in the first drive does not cause a rotational movement into the second drive that affects the tracking or seek operation. Some further embodiments position drives in a herringbone pattern to redirect air flow in addition to reducing rotational-acceleration vibration interaction. Other embodiments include a printed wire circuit board mounted to reduce the rotational-acceleration vibration interaction. | 10-14-2010 |
Glenn Wendel, Pipe Creek, TX US
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20130152889 | LOST-MOTION VARIABLE VALVE ACTUATION SYSTEM - Valve actuation systems are disclosed herein that allow valve opening timing to be varied using a cam phaser and that allow valve closing timing to be varied using a lost-motion system. In one embodiment, an actuation system is provided that has a locked configuration in which a bearing element is held in place between a cam and a rocker to transmit cam motion to an engine valve. The actuation system also has an unlocked configuration in which the bearing element is permitted to be at least partially ejected from between the cam and rocker, such that cam motion is not transmitted to the engine valve. The actuation system is switched to the unlocked configuration by draining fluid therefrom through a main valve which is piloted by a trigger valve. The actuation system also includes integrated autolash and seating control functionality. | 06-20-2013 |
Hans G. Wendel, Cold Spring Harbor, NY US
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20090186839 | Model for studying the role of genes in chemoresistance - The invention provides novel inhibitors of protein translation initiation and inhibitors of eIF4F activity that can increase chemosensitivity or diminish or reverse chemoresistance in growth transformed cells and thereby reduce hyperproliferative conditions, such as cancer progression, in select patient populations having particular tumor genotypes. The invention also provides methods which target translation initiation controls in growth-transformed cells, such as tumor subtypes with altered expression of a gene activity, including the human akt, bcl-2, eIF4E, eIF4A or PTEN activities, to restore drug sensitivity in vivo in a genotype selective manner. In one aspect, the inhibitors of translation initiation of the invention are rocaglates, i.e., cyclopenta[b]benzofurons, which increases chemosensitivity or diminishes or reverses chemoresistance either alone or in combination, additively or synergistically, with other agents that alter growth or death. Preferably, the rocaglate is silvestrol, which is used alone or in combination with doxorubicin to reverses chemoresistance in PTEN-deficient lymphomas or eIF4E-over-expressing lymphomas and to promote cancer remission. | 07-23-2009 |
Hans-Guido Wendel, New York, NY US
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20130064810 | Methods and Compositions for the Detection and Treatment of Cancer involving miRNAs and miRNA Inhibitors and Targets - The present invention relates to microRNAs (miRNAs) which are associated with cancer, particularly including hematologic malignancies, and particularly T-cell acute lymphoblastic leukemia (T-ALL), and to the assessment and modulation thereof in the treatment and management of cancer. The present invention is directed to methods and compositions for diagnosing and treating cancer, particularly T-ALL, by modulating miRNAs, and the use of miRNAs and antagonists thereof, particularly antagomirs, for predicting and assessing response to treatment, in assays for isolating and selecting antagists, and as compositions for the treatment and management of cancer. Methods and compositions are provided for treatment or alleviation of cancer, particularly T-ALL, with antagonists/antagomirs of miRNAs, particularly one or more of miR-19b, miR-20a, miR26, miR92, miR148 and miR223. | 03-14-2013 |
20140080838 | Methods for Treatment of Lymphomas with Mutations in Cell Cycle Genes - The present disclosure identifies a novel subtype of follicular lymphoma (FL) characterized by dysregulation of the cyclin/CDK/RB proliferative pathway. This subtype of FL is associated with increased malignancy and mortality, relative to FL which is not associated with cell cycle dysregulation. Accordingly, this disclosure presents novel methods to subtype FL and stratify patient risk by detection of biomarkers associated with RB inactivation. This disclosure further presents novel therapies for the treatment of FL subtyped by inactivation of RB. | 03-20-2014 |
20150219624 | METHODS FOR IDENTIFYING ANTI-CANCER COMPOUNDS - Methods are provided for identifying agents capable of modulating cap-dependent RNA translation by comparing translation efficiency in the presence and absence of the agent in an in-vitro or in-vivo translation system that comprises eIF4A and an mRNA having one or more eIF4A-dependent translation-controlling motifs. The modulation of translation in the presence of the agent indicates the agent as capable of modulating cap-dependent mRNA translation. The method can be used to identify anti-cancer agents and oncogenes that may be responsible for tumorigenesis. | 08-06-2015 |
Hans-Guido Wendel, New York City, NY US
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20140079698 | ANTI-TUMOR ANTIBODY-TUMOR SUPPRESSOR FUSION PROTEIN COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT OF CANCER - The present invention is directed to methods and compositions for treating cancer, including, hematologic malignancies, such as B-cell malignancies, with anti-tumor antibody-tumor suppressor fusion proteins in order to selectively restore tumor suppressor gene function to cancer cells in which such tumor suppressor gene function has been lost. The present invention is also directed to methods and compositions for diagnosing cancer and for predicting and assessing response to treatment. | 03-20-2014 |
Harold A. Wendel, Encinitas, CA US
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20090030848 | SYSTEMS AND METHODS FOR ONLINE SALES NEGOTIATIONS - An online negotiations system including hardware and software, may be configured to direct or outsource online negotiations, in real or near-real time, for goods and services listed and described on an online site. Outsourcing of negotiations may be managed to provide an agent to negotiation on behalf of a seller with respect to a listed item, wherein agents are typically managed and allocated independently of sellers by an online negotiations management system including an outsourcing management module having a central queue. | 01-29-2009 |
Karen J. Wendel, San Francisco, CA US
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20140188677 | KNOW YOUR CUSTOMER EXCHANGE SYSTEM AND METHOD - The systems and methods described herein attempt to overcome the drawbacks discussed above by providing a know your customer (KYC) exchange system and method that allows for easy transmission of corporate and individual identification information to a selected financial institution. The KYC exchange system, which may be implemented by a bank, a corporation, or other party, receives as an input the laws and practicalities of a plurality of nations and regions, as well as KYC business policies of a plurality of financial institutions located across the plurality of nations and regions. Using the collected input information, the system is able to provide feedback to individuals and corporations using the exchange system regarding whether the individual or corporation has provided all of the requested and necessary identification and financial services information. | 07-03-2014 |
Kathy Wendel, Stockton, CA US
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20120164282 | Light Glaze for Popcorn - Disclosed are microwave popcorn articles comprising any conventional microwave popcorn bag, and a food charge disposed therein comprising kernel popcorn, fat, salt and sufficient amounts of a heat tolerant glaze forming carbohydrate ingredient such as isomalt to provide the finished popped popcorn with sweet glaze coating. Methods of preparing such microwave popcorn articles are disclosed wherein the isomalt in particulate form in a separate step and preferably after the kernel popcorn and fat have been added to the bag. | 06-28-2012 |
Lance Frederick Wendel, Kula, HI US
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20090101184 | Spa filter cleaning device - A spa filter cartridge cleaning apparatus configured to substantially remove contaminants from a spa filter cartridge. The cleaning apparatus further includes a container that has a plurality of walls configured to define an interior volume of sufficient size to receive a spa filter cartridge therein. A cleaning cylinder is disposed within the container and functions to be mateably connected with the hollow core of a spa filter cartridge. The cleaning cylinder further includes a plurality of apertures that function to discharge cleaning liquid disposed within the cleaning cylinder. An attachment mechanism operably connects the cleaning cylinder to a water source. A pinion gear is operably connected to one end of the cleaning cylinder and functions to rotate the cleaning cylinder for increased cleaning effectiveness of the spa filter cartridge secured thereto. | 04-23-2009 |
Otto William Wendel, Young Harris, GA US
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20100292667 | Self-Neutralizing Acid Peel for Dermatologic Use - A dermatologic peel comprising alpha hydroxyl acid and metal hydroxide nanocomplexes as neutralizing agents to continually reduce the activity of the system when the acid and neutralizer components are mixed. For example, a 30% glycolic acid gel mixed with a fluidized magaldrate neutralizer can be applied to the skin and will self-neutralize to a skin-compatible pH within a few minutes, effectively exfoliating the skin without a separate neutralization step. The peel is advantageously applied from a two-component system that mixes the components. | 11-18-2010 |
20120115953 | Self-Neutralizing Acid Peel for Dermatologic Use - A dermatologic peel comprising alpha hydroxyl acid and metal hydroxide nanocomplexes as neutralizing agents to continually reduce the activity of the system when the acid and neutralizer components are mixed. For example, a 30% glycolic acid gel mixed with a fluidized magaldrate neutralizer can be applied to the skin and will self-neutralize to a skin-compatible pH within a few minutes, effectively exfoliating the skin without a separate neutralization step. The peel is advantageously applied from a two-component system that mixes the components. | 05-10-2012 |
Sebastian Wendel, Manhattan, KS US
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20150224211 | LEUKOCYTES AS DELIVERY CELLS FOR IMAGING AND DISEASE THERAPY - Theranostic methods are described herein, which are useful in diagnosing and/or treating infection, inflammation, and/or cancer. The methods utilize naturally-occurring leukocytes for in situ photodynamic therapy and imaging, and for the delivery of targeted therapies to the infection, inflammation, and/or cancer. | 08-13-2015 |
Stephen A. Wendel, Hyattsville, MD US
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20100280935 | System and Method for Creating and Managing Financially-Related Goals - The invention provides computer-implemented behavioral science systems and methods for creating, managing, tracking, incentivizing, and/or reaching one or more financial health goals. The invention may include a software application supported by one or more computing devices that enables a website or other user interfaces that facilitate, inter alia, creation of financial goals, monitoring of financial goals, updating created goals for specific individuals using complex behavior modeling, and incentive structures based on behavioral science tailored and individualized for participants. | 11-04-2010 |
Steve Wendel, St. Marys, PA US
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20120107662 | THERMAL MANAGEMENT MATRIX - A thermal management matrix for an electrochemical cell array including a plurality of electrochemical cell elements, the thermal management matrix at least in part enveloping the electrochemical cell array and being in thermal contact therewith. The thermal management matrix includes mainly expanded graphite, wherein the expanded graphite is arranged in the form of a block-like structure and the block includes at least one layer of expanded graphite having a higher in-plane thermal conductivity than the layers neighboring the layer with higher in-plane thermal conductivity. The thermal management matrix may also include phase change materials as a latent heat storage material. | 05-03-2012 |
Thomas D. Wendel, Nashua, NH US
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20100072194 | Package conveyor for continuous process microwave applicator - A mechanism for constraining a product package as it is conveyed through a microwave applicator. In one preferred embodiment, the conveyor is provided by a pair of parallel guide belts arranged to travel through a microwave applicator. The guide belts have a series of slots or other guide elements formed therein. The guide elements engage edges of the product packages. In one arrangement, the pair of belts are disposed on either side of a series of packages, and thus constrain the location of the packages in three dimensions. | 03-25-2010 |
20100126988 | Apparatus and method for mass sterilization and pasteurization of food products - An apparatus and method for processing food products is provided. The product conditioning system includes an inlet assembly, a pressurizeable tunnel and an outlet assembly. The inlet assembly and outlet assembly include a pair of vertically extending pressure vessels having entry and exit openings which are both sealable by doors to provide liquid and gaseous tight seals. The inlet and outlet assembly pressure vessels further include a pair of vertically extending parallel screws for transporting food products from one end of the pressure vessel to the other. The pressurizeable tunnel includes a heating stage having microwave sources for irradiating food products so as to pasteurize or sterilize prepackaged food. The pressurizeable tunnel further includes a heat maintenance stage and product cooling stage. Both the heat maintenance stage and product cooling stage include vertically extending pressure vessels. Within each pressure vessel, two pairs of parallel rotating screws are positioned for moving food products through a liquid environment at a desired temperature for continued pasteurization or sterilization in the heat maintenance stage, and product cooling within the cooling stage. | 05-27-2010 |
Thomas Dewayne Wendel, Nashua, NH US
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20140261158 | FURNANCE EMPLOYING COMPONENTS FOR USE WITH GRAPHITE HOT ZONE - A furnace for growing sapphire crystal in which the furnace comprises a furnace housing; a hot zone which comprises insulation and a heater which are both accommodated within the furnace housing; a crucible located within the hot zone and the crucible has an opening. Either a crucible lid covers the opening of the crucible, and the crucible lid has a first conduit which extends therefrom or a crucible enclosure surrounds at least a side wall and a top portion of the crucible and the crucible enclosure is impermeable to at least carbon preventing carbon contamination of a melt contained within the crucible. | 09-18-2014 |
William Wendel, Hiawassee, GA US
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20130313465 | FIRE FIGHTING AND FIRE RETARDANT COMPOSITIONS - Disclosed herein are fire-fighting compositions, and methods thereof, comprising a surfactant and a fraction of a fermentation mixture comprised of yeast exoproteins, where the proteins enhance ability of water to extinguish Class A, Class B and Class K fires, as defined by the National Fire Protection Association. In one embodiment the surfactant is optimized to wet and penetrate into the substrate, for example wood, as in a Class A fire. In a second embodiment, the surfactant is optimized for foaming to provide fire fighting protection in a Class B fire. Further embodiments include methods for using the same protein-surfactant fire fighting composition for both polar (e.g., alcohol) and non-polar combustible liquids. In yet another embodiment, methods are described where the proteins comprise stress shock proteins and where the residual protein-surfactant combination that is not degraded from the fire acts to stimulate resident bacterial populations to accelerate the biodegradation of residual hydrocarbons and surfactants from the composition. In another embodiment, the compositions are free of solvents, fluorine-free as in fluoro surfactants and fluoro-polymers. | 11-28-2013 |