Patent application number | Description | Published |
20100041599 | Compositions and methods for bone formation, bone remodeling and toxin protection - The present invention identifies compounds that disrupt the interaction between anthrax proteins and LRP5/6 receptors, resulting in a reduction in anthrax toxicity. The compounds act to disrupt the intracellular transport of toxin complexes into a target cell. The present invention also provides methods for testing the effect of compounds on Wnt activity, through the use of in vitro experiments involving cells that have in at least one gene mutation involved in the Wnt pathway. | 02-18-2010 |
20110105606 | Compositions and methods affecting the signaling pathways of LRP receptors - The present invention relates to the field of therapeutic methods, compositions and uses thereof, that affect, directly or indirectly, the behavior of LRP receptors. These compositions and methods result in the treatment of inflammatory, immunological and metabolic conditions. More particularly, the methods and compositions of the invention are directed to the identification of small molecules, drugs and/or pharmacological agents that affect the Wnt pathway by affecting normal complex formation among various signaling receptors, the LRP5 and LRP6 receptor, and related ligands. | 05-05-2011 |
20120184616 | Methods for treating inflammation - The present invention relates to the field of therapeutic methods, compositions and uses thereof, that affect, directly or indirectly, the behavior of LRP receptors. These compositions and methods result in the treatment of inflammatory, immunological and metabolic conditions. More particularly, the methods and compositions of the invention are directed to the identification of small molecules, drugs and/or pharmacological agents that affect the Wnt pathway by affecting normal complex formation among various signaling receptors, the LRP5 and LRP6 receptor, and related ligands. | 07-19-2012 |
20150216832 | METHOD FOR TREATING INFLAMMATION BY ADMINISTERING A COMPOUND WHICH BINDS LDL-RECEPTOR-RELATED PROTEIN (LRP) LIGAND BINDING DOMAIN - The present invention relates to the field of therapeutic methods, compositions and uses thereof, that affect, directly or indirectly, the behavior of LRP receptors. These compositions and methods result in the treatment of inflammatory, immunological and metabolic conditions. More particularly, the methods and compositions of the invention are directed to the identification of small molecules, drugs and/or pharmacological agents that affect the Wnt pathway by affecting normal complex formation among various signaling receptors, the LRP5 and LRP6 receptor, and related ligands. | 08-06-2015 |
Patent application number | Description | Published |
20100041020 | Methods for detecting the presence, location or quantity of targets using novel dyes - The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties. | 02-18-2010 |
20100228008 | Dyes linked to target molecules, oligonucleotides or polynucleotides comprising dye molecules, composite dyes and other compositions useful for detecting or quantifying desirable target molecules - The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties. | 09-09-2010 |
20120040430 | Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties. | 02-16-2012 |
20130045480 | Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules - The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties. | 02-21-2013 |
20130109847 | Detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes | 05-02-2013 |
Patent application number | Description | Published |
20130045697 | Method, control apparatus and wireless terminal for reducing radiation harm of wireless terminal - The disclosure discloses a method, a control apparatus and a wireless terminal for reducing radiation harm of a wireless terminal, belonging to the field of wireless radiation protection. The method comprises: a control apparatus detects whether there is an object approaching an antenna of a wireless terminal; and the control apparatus adjusts an output power of a transmitter of the wireless terminal connected with the antenna to an output protection power so as to reduce an SAR value of the antenna to a set value, when it is detected that there is an object approaching the antenna. The method can reduce radiation of the wireless terminal to human bodies, and is applicable to wireless communication terminals. | 02-21-2013 |
20150229868 | Video Playback System and Method - The embodiments of the present document disclose a system and method for playing videos, and the system includes: a streaming media server, configured to send a video stream to a real-time video intelligent analysis system and video surveillance center, and receive and buffer a text stream corresponding to the video stream from the real-time video intelligent analysis system, and send the text stream to the video surveillance center; the real-time video intelligent analysis system, configured to perform real-time analysis on the video stream and output the text stream corresponding to the video stream to the streaming media server; the video surveillance center, configured to request for and receive the video stream and the text stream from the streaming media server, compensate for a lost text frame in the text stream according to the video stream, and output mixed videos of overlay video stream and text stream. | 08-13-2015 |
Patent application number | Description | Published |
20140073048 | LOW MOLECULAR WEIGHT BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS - A branched polyamine comprises about 8 to about 12 backbone tertiary amine groups, about 18 to about 24 backbone secondary amine groups, a positive number n′ greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): | 03-13-2014 |
20140080215 | BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS - A branched polyamine comprises about 45 to about 70 backbone tertiary amine groups, about 90 to about 140 backbone secondary amine groups, a positive number n′ greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): | 03-20-2014 |
20140377945 | FLOATING GATE FORMING PROCESS - A floating gate forming process includes the following steps. A substrate containing active areas isolated from each other by isolation structures protruding from the substrate is provided. A first conductive material is formed to conformally cover the active areas and the isolation structure. An etch back process is performed on the first conductive material to respectively form floating gates separated from each other in the active areas. | 12-25-2014 |
20150014761 | SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF - A method for manufacturing a semiconductor device includes the following steps. At first, two gate stack layers are formed on a semiconductor substrate, wherein each of the gate stack layers includes a top surface and two side surfaces. A conductive material layer is deposited to conformally cover the top surface and the two side surfaces of each of the gate stack layers. Then, a cap layer is deposited to conformally cover the conductive material layer. Finally, the cap layer and the conductive material layer above the top surface of each of the gate stack layers are removed to leave the cap layer adjacent to the two side surfaces of each of the gate stack layers and covering a portion of the conductive material layer. | 01-15-2015 |
20150140800 | METHOD OF FABRICATING SEMICONDUCTOR DEVICE - A method of fabricating a semiconductor device includes the following steps. At least a first gate stack layer and at least a second gate stack layer protruding from a conductive layer on a substrate are provided. Subsequently, two spacers and a protective layer are formed on the conductive layer, and the two spacers and the protective layer jointly surround the protruded first gate stack layer and the protruded second gate stack layer. The two spacers and the protective layer are used as a mask to remove a part of the conductive layer. Afterwards, the two spacers and the protective layer are removed. | 05-21-2015 |
20150206894 | SEMICONDUCTOR STRUCTURE AND LAYOUT STRUCTURE FOR MEMORY DEVICES - A layout structure for memory devices includes a plurality of first gate patterns, a plurality of first landing pad patterns, a plurality of dummy patterns, a plurality of second landing pad patterns, and a plurality of second gate patterns. The first landing pad patterns are parallel with each other and electrically connected to the first gate patterns. The dummy patterns and the first landing pad patterns are alternately arranged, and the second landing pad patterns are respectively positioned in between one first landing pad pattern and one dummy pattern. The second gate patterns are electrically connected to the second landing pad patterns. | 07-23-2015 |
20150249158 | SEMICONDUCTOR STRUCTURE AND METHOD FOR MANUFACTURING THE SAME - A semiconductor structure and a method for manufacturing the same are provided. The semiconductor structure comprises a substrate, a first gate structure, a second gate electrode, a third gate electrode and a protective layer. The first gate structure comprises a first gate electrode disposed on the substrate and a first gate dielectric covering the first gate electrode. The second gate electrode is disposed on and electrically isolated from the first gate electrode. The first gate structure has an extending portion relative to the second gate electrode. The third gate electrode is disposed adjacent to and electrically isolated from the first gate electrode and the second gate electrode. The third gate has an extending portion between a lower surface of the protective layer and an upper surface of the extending portion of the first gate structure. | 09-03-2015 |