Weber, Hamburg
Bernahrd Weber, Hamburg DE
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20080267985 | Variants of Group 1 Allergens from Poaceae Having Reduced Allergenicity and Maintained T-Cell Reactivity - The present invention relates to the preparation and use of variants of the group 1 allergens of the Poaceae (sweet grasses) which are characterised by reduced IgE reactivity compared with the known wild-type allergens and at the same time by substantially maintained reactivity with T-lymphocytes. These hypoallergenic allergen variants can be employed for the specific immunotherapy (hyposensitisation) of patients having grass pollen allergy or for the preventive immunotherapy of grass pollen allergies. | 10-30-2008 |
Bernhard Weber, Hamburg DE
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20100158955 | Phl p 5a derivatives having reduced allergeneity and retained t-cell reactivity - The present invention relates to the preparation and use of variants of the group 5 allergen of the Pooideae which are characterised by reduced IgE reactivity compared with the known wild-type allergens and at the same time by substantially retained reactivity with T lymphocytes. These hypoallergenic allergen variants can be employed for the specific immunotherapy (hyposensitisation) of patients having grass pollen allergy or for the preventative immunotherapy of grass pollen allergies. | 06-24-2010 |
20130224251 | VARIANTS OF GROUP 6 ALLERGENS OF THE TRUE GRASSES HAVING REDUCED ALLERGENEITY DUE TO MUTAGENESIS OF PROLINE RESIDUES - The present invention relates to the preparation and use of recombinant variants of group 6 allergens of the Poaceae (true grasses), which are characterised by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes. | 08-29-2013 |
20140255434 | PHL P 5A DERIVATIVES HAVING REDUCED ALLERGENEITY AND RETAINED T-CELL REACTIVITY - The present invention relates to the preparation and use of variants of the group 5 allergen of the Pooideae which are characterised by reduced IgE reactivity compared with the known wild-type allergens and at the same time by substantially retained reactivity with T lymphocytes. These hypoallergenic allergen variants can be employed for the specific immunotherapy (hyposensitisation) of patients having grass pollen allergy or for the preventative immunotherapy of grass pollen allergies. | 09-11-2014 |
20150071953 | VARIANTS OF GROUP 6 ALLERGENS OF THE TRUE GRASSES HAVING REDUCED ALLERGENEITY DUE TO MUTAGENESIS OF PROLINE RESIDUES - The present invention relates to the preparation and use of recombinant variants of group 6 allergens of the Poaceae (true grasses), which are characterised by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes. | 03-12-2015 |
20150140024 | VARIANTS OF GROUP 5 ALLERGENS OF THE TRUE GRASSES HAVING REDUCED ALLERGENEITY DUE TO MUTAGENESIS OF PROLINE RESIDUES - The present invention relates to the preparation and use of recombinant variants of group 5 allergens of the Poaceae (true grasses), which are characterised by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes. | 05-21-2015 |
Frank Michael Weber, Hamburg DE
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20160110869 | CORTICAL BONE SEGMENTATION FROM MR DIXON DATA - The present invention relates to a method for segmenting MR Dixon image data. A processor and a computer program product are also disclosed for use in connection with the method. The invention finds application in the MR imaging field in general and more specifically may be used in the generation of an attenuation map to correct for attenuation by cortical bone during the reconstruction of PET images. In the method, a surface mesh is adapted to a region of interest by: for each mesh element in the surface mesh: selecting a water target position based on a water image feature response in the MR Dixon water image; selecting a fat target position based on a fat image feature response in the MR Dixon fat image; and displacing each mesh element from its current position to a new position based on both its water target position and its corresponding fat target position. | 04-21-2016 |
Hans-Jürgen Weber, Hamburg DE
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20150322608 | MULTI-NEEDLE MACHINE AND METHOD FOR PRODUCING REINFORCED MATERIALS - This relates to the manufacturing of reinforced materials, such as reinforced cellular materials or reinforced textiles, for example. Reinforcement is achieved by including a textile semi-finished product into the material to be reinforced, by providing the semi-finished product at the rear side of the material in a zigzag or wave-like manner and then pulling the semi-finished product through the material by a plurality of needles. Thus, the manufacturing process may be performed in a time saving manner. | 11-12-2015 |
20150323291 | BALLISTIC PROTECTIVE MEASURES - This relates to measures for protection against striking and penetrating objects. To provide ballistic protection measures that are as light and efficient as possible while having a compact design, a ballistic protective component for protection against penetrating foreign objects comprises a first layer and a second layer, which are mutually spaced by an intermediate layer, that together with a plurality of reinforcement elements, form a sandwich component. Further, an intermediate sheet made of core material is arranged in the intermediate layer. At least one sheet is arranged in the intermediate layer. The ballistic protective material is a fibrous sheet material. In another example, the ballistic protective material comprises dilatant material. The reinforcement elements are tensile and compressive resistant and extend from the first to the second layer through the at least one sheet of ballistic protective material, and, in one example, through the at least one intermediate sheet. | 11-12-2015 |
Markus Joerg Weber, Hamburg DE
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20110042516 | WINDOW ELEMENT FOR A DOUBLE-SHELL SKIN FIELD OF AN AIRCRAFT FUSELAGE CELL - A window element for a double-shell skin field of an aircraft fuselage cell includes a window frame having a window module disposed in the frame, wherein the frame is disposed in an opening of the double-shell skin field, and wherein the frame is connected to the double-shell skin field by a surrounding embrasure profile positioned against a core structure of the skin field at least in some regions, wherein the core structure includes an inner and an outer covering layer. | 02-24-2011 |
20120056037 | FUSELAGE CELL STRUCTURE FOR AN AIRCRAFT IN HYBRID DESIGN - A fuselage cell structure for an aircraft includes at least two skin panels including at least one double shell skin panel and at least one monolithic skin panel. At least one brace which is at least one of a longitudinal and a transverse brace is disposed so as to form at least one of a longitudinal seam and a transverse seam between the at least one double shell skin panel and the at least one monolithic skin panel. The fuselage cell structure includes at least one of a longitudinal bracket and a load transfer point. The longitudinal bracket is disposed in a region of the longitudinal seam and includes a first and a second longitudinal flange that are disposed offset with respect to one another and connected by a web. The load transfer point is disposed in a region of the transverse seam so as to connect the longitudinal brace disposed on the at least one monolithic skin panel to the at least one double shell skin panel. | 03-08-2012 |