Patent application number | Description | Published |
20090187255 | CERAMIC METAL COMPOSITE FOR ORTHOPAEDIC IMPLANTS - The invention relates to an orthopedic implant made of a ceramic metal composite. The composite ( | 07-23-2009 |
20100174383 | CERAMIC LAYERED MEDICAL IMPLANT - A new composition and medical implant made there from comprises a thick diffusion hardened zone, and layered ceramic surface. Orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition are disclosed. | 07-08-2010 |
20120306121 | CERAMIC METAL COMPOSITE FOR ORTHOPAEDIC IMPLANTS - The invention relates to an orthopaedic implant made of a ceramic metal composite. The composite includes one phase that is a biocompatible metal or metal alloy and a second phase of ceramic particles examples of which include carbides, nitrides and/or oxides. In some embodiments, the implant comprises a homogeneous ceramic layer as part of a multilayered composition. In some embodiments, the multilayered composition comprises a homogeneous metal layer. | 12-06-2012 |
20130230640 | CERAMIC LAYERED MEDICAL IMPLANT - A new composition and medical implant made there from comprises a thick diffusion hardened zone, and layered ceramic surface. Orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition are disclosed. | 09-05-2013 |
20140046453 | DIFFUSION-HARDENED MEDICAL IMPLANT - The present invention relates to a new composition and medical implant made therefrom, the composition comprising a thick diffusion hardened zone, and preferably further comprising a ceramic layer. The present invention relates to orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition. | 02-13-2014 |
Patent application number | Description | Published |
20090042855 | BENZAMIDE mGluR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME - In one aspect, the invention relates to compounds, including phenylethynylbenzamide derivatives, cycloalkylethynylbenzamide derivatives, styrylbenzamide derivatives, 4-(3-phenyl-1,2,4-oxadiazol-5-yl)benzamide derivatives, 4-(pyridinylethynyl)benzamide derivatives, and N | 02-12-2009 |
20090270362 | BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME - In one aspect, the invention relates to bicyclic MGluR5 positive allosteric modulators, for example 6-(phenylethynyl)-3,4-dihydroisoquinolin-1(2H)-one, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 10-29-2009 |
20110124663 | SUBSTITUTED DIOXOPIPERIDINES AND DIOXOPYRROLIDINES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION - In one aspect, the invention relates to compounds having a general structure: | 05-26-2011 |
20110152299 | SUBSTITUTED BENZAMIDE ANALOGS AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME - Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention | 06-23-2011 |
20110166158 | SUBSTITUTED PHENYLAMINE CARBOXAMIDE ANALOGS AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME - Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 07-07-2011 |
20110172247 | SUBSTITUTED HETEROARYLAMINE CARBOXAMIDE ANALOGS AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME - Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention | 07-14-2011 |
20110172248 | SUBSTITUTED HETEROARYLAMIDE ANALOGS AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME - Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 07-14-2011 |
20110183980 | O-BENZYL NICOTINAMIDE ANALOGS AS MGLUR5 POSITIVE ALLOSTERIC MODULATORS - In one aspect, the invention relates to O-benzyl nicotinamide analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 07-28-2011 |
20110319429 | SUBSTITUTED 1,1,3,1-TETRAOXIDOBENZO[D][1,3,2]DITHIAZOLES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION - Compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) and methods of using the compounds. | 12-29-2011 |
20120028955 | BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME - In one aspect, the invention relates to bicyclic mGluR5 positive allosteric modulators, for example 6-(phenylethynyl)-3,4-dihydroisoquinolin-1(2H)-one, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 02-02-2012 |
20120028956 | BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME - In one aspect, the invention relates to bicyclic mGluR5 positive allosteric modulators, for example 6-(phenylethynyl)-3,4-dihydroisoquinolin-1(2H)-one, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 02-02-2012 |
20120088791 | AMIDOBIPIPERIDINECARBOXYLATE M1 ALLOSTERIC AGONISTS, ANALOGS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME - In one aspect, the invention relates to compounds having a general structure: Formula (I) which are useful as allosteric agonists of the M | 04-12-2012 |
20120184556 | SUBSTITUTED ENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS - Disclosed are substituted benzoimidazolesulfonamides and substituted indolesulfonamides as mGluR4 potentiators. | 07-19-2012 |
20120245153 | MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION - Compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) and use thereof. | 09-27-2012 |
20120245185 | ARYL AND HETEROARYL SULFONES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION - In one aspect, the invention relates to sulfone compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction. | 09-27-2012 |
Patent application number | Description | Published |
20090125116 | HINGED JOINT SYSTEM - Methods, systems, and devices for replacement of a joint with a prosthetic system that replicates the natural kinematics of the joint is disclosed. A prosthetic system according to one embodiment includes a tibial component having a tibial plateau and a tibial stem portion, the tibial plateau having a top side and a bottom side, a tibial insert, with a bearing surface adapted to be positioned on the top side of the tibial plateau, a femoral component having a base portion and a central housing, the femoral component having an axis of extension-flexion rotation, the base portion having a pair of condyles, a mechanical linkage component linking the tibial component with the femoral component and with the tibial insert in between the tibial component and the femoral component, so that there is a center of contact between the condyles and the bearing surface, the mechanical linkage component adapted to allow the center of contact to move posteriorly during flexion, provide for the movement of the axis of extension-flexion rotation in the superior-inferior direction, and allow rotation of the tibial component, the bearing surface, and the femoral component about a superior-inferior axis in order to provide and control the natural kinematics of the knee joint. | 05-14-2009 |
20130325135 | HINGED JOINT SYSTEM - Methods, systems, and devices for replacement of a joint with a prosthetic system that replicates the natural kinematics of the joint is disclosed. A prosthetic system according to one embodiment includes a tibial component having a tibial plateau and a tibial stem portion, the tibial plateau having a top side and a bottom side, a tibial insert, with a bearing surface, adapted to be positioned on the top side of the tibial plateau, a femoral component having a base portion and a central housing, the femoral component having an axis of extension-flexion rotation, the base portion having a pair of condyles, a mechanical linkage component linking the tibial component with the femoral component and with the tibial insert in between the tibial component and the femoral component, so that there is a center of contact between the condyles and the bearing surface, the mechanical linkage component adapted to allow the center of contact to move posteriorly during flexion, provide for the movement of the axis of extension-flexion rotation in the superior-inferior direction, and allow rotation of the tibial component, the bearing surface, and the femoral component about a superior-inferior axis in order to provide and control the natural kinematics of the knee joint. | 12-05-2013 |
20150051490 | ULTRASOUND SCANNING - A system for ultrasound scanning includes an ultrasound transducer assembly configured to generate ultrasound scan data indicative of surface features of bony anatomy. The system includes a deformable cuff that transmits ultrasound when filled with an ultrasound-conductive medium. The system also includes a transference mechanism configured to move the ultrasound transducer assembly relative to the deformable cuff along a path while maintaining contact between the ultrasound transducer assembly and the cuff. The transference mechanism is also configured to generate position data indicative of different positions of the ultrasound transducer assembly along the path. | 02-19-2015 |
Patent application number | Description | Published |
20090076235 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM - This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methine compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses. | 03-19-2009 |
20090185988 | POLYVINYL ULTRAVIOLET LIGHT ABSORBERS FOR PERSONAL CARE - UV-absorbing polymers and copolymers suitable for Composition into sunscreens for the protection of human skin. The UV-absorbing chromophoric monomers chosen are simple and easily synthesized. With the correct choice of chromophoric monomer or mixture of monomers, protection against UV-A radiation or against both UV-A and UV-B radiation can be achieved. With the correct choice of comonomer, copolymers produced as aqueous latex emulsions or as Polyethylene Glycol solutions can also be achieved. | 07-23-2009 |
20100085534 | OPHTHALMIC DEVICES HAVING A HIGHLY SELECTIVE VIOLET LIGHT TRANSMISSIVE FILTER AND RELATED METHODS - Ophthalmic devices are provided having a violet-light vertical cut-off filter abruptly absorbs light between the wave lengths of between approximately and 400 nm and 450 nm such that a curve when plotted as percent transmission versus wavelength has the shape as depicted in FIG. | 04-08-2010 |
20120013844 | OPHTHALMIC DEVICES HAVING A HIGHLY SELECTIVE VIOLET LIGHT TRANSMISSIVE FILTER AND RELATED METHODS - Ophthalmic devices are provided having a violet-light vertical cut-off filter abruptly absorbs light between the wave lengths of between approximately and 400 nm and 450 nm such that a curve when plotted as percent transmission versus wavelength has the shape as depicted in FIG. | 01-19-2012 |
20130018159 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM - This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methane compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses. | 01-17-2013 |
20130324717 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM - This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methane compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses. | 12-05-2013 |
Patent application number | Description | Published |
20080250788 | POWER GENERATION AND SPACE CONDITIONING USING A THERMODYNAMIC ENGINE DRIVEN THROUGH ENVIRONMENTAL HEATING AND COOLING - A thermodynamic engine is configured to convert heat provided in the form of a temperature difference to a nonheat form of energy. Heat is directed through a heating loop in thermal contact with a first side of the thermodynamic engine. A second side of the thermodynamic engine is coupled to an environmental cooling loop in thermal contact with an environmental cooling device. The thermodynamic engine is operated to dispense heat from the second side of the thermodynamic engine through the environmental cooling loop into the environmental cooling device. Operation of the thermodynamic engine thereby generates the nonheat form of energy from the temperature difference established between the first side and the second side of the thermodynamic engine. | 10-16-2008 |
20120102948 | POWER GENERATION AND SPACE CONDITIONING USING A THERMODYNAMIC ENGINE DRIVEN THROUGH ENVIRONMENTAL HEATING AND COOLING - A thermodynamic engine is configured to convert heat provided in the form of a temperature difference to a nonheat form of energy. Heat is directed through a heating loop in thermal contact with a first side of the thermodynamic engine. A second side of the thermodynamic engine is coupled to an environmental cooling loop in thermal contact with an environmental cooling device. The thermodynamic engine is operated to dispense heat from the second side of the thermodynamic engine through the environmental cooling loop into the environmental cooling device. Operation of the thermodynamic engine thereby generates the nonheat form of energy from the temperature difference established between the first side and the second side of the thermodynamic engine. | 05-03-2012 |
20130008081 | METHODS AND SYSTEMS FOR MAKING LIQUID FUEL FROM CELLULOSE IN THERMAL REACTORS - Methods and systems are disclosed for making a liquid fuel from a compound having carbon, oxygen, and hydrogen, such cellulosic biomass, which includes cellulose, lignin, hemicellulose, and combinations thereof. The compound is combined with water to produce a wet form of the compound, which is transferred into a reaction processing chamber. The wet form of the compound is heated within the reaction chamber such that elements of the wet form of the compound dissociate and react. One reaction product is the liquid fuel. | 01-10-2013 |
20130011756 | CELLULOSIC BIOMASS PROCESSING FOR HYDROGEN EXTRACTION - Methods are disclosed for extracting hydrogen from a biomass compound comprising carbon, oxygen, and hydrogen. The biomass may include cellulose, lignin, and/or hemicellulose. Water is combined with the compound to produce a wet form of the compound. The wet form of the compound is transferred into a reaction processing chamber. The wet form of the compound is heated within the reaction chamber such that elements of the compound dissociate and react, with one reaction product comprising hydrogen gas. The hydrogen gas is processed to generate electrical power. | 01-10-2013 |
20130171532 | CONVERSION OF C-O-H COMPOUNDS INTO HYDROGEN FOR POWER OR HEAT GENERATION - Methods are disclosed for generating electrical power from a compound comprising carbon, oxygen, and hydrogen. Water is combined with the compound to produce a wet form of the compound. The wet form of the compound is transferred into a reaction processing chamber. The wet form of the compound is heated within the reaction chamber such that elements of the compound dissociate and react, with one reaction product comprising hydrogen gas. The hydrogen gas is processed to generate electrical power. | 07-04-2013 |
20140059921 | METHODS, SYSTEMS, AND DEVICES FOR CONTINUOUS LIQUID FUEL PRODUCTION FROM BIOMASS - Methods, systems, and devices for continuous production of liquid fuels from biomass are provided. Some embodiments utilize a thermochemical process to produce a bio-oil in parallel with a thermochemical process to produce a hydrogen-rich synthesis gas. Both product streams may be fed into a third reaction chamber that may enrich the bio-oil with the hydrogen gas, for example, in a continuous production process. One product stream may include a liquid fuel such as diesel. Some embodiments may also produce other product streams including, but not limited to, electrical power generation and/or biochar. | 03-06-2014 |
20140093446 | METHODS, SYSTEMS, AND DEVICES FOR SYNTHESIS GAS RECAPTURE - Methods, systems, and/or devices for synthesis gas recapture are provided, which may include methods, systems, and/or devices for filtering a synthesis gas stream. In some cases, tars, particulates, water, and/or heat may be removed from the synthesis gas stream through the filtering of the synthesis gas stream. The filtered synthesis gas stream may then be captured and/or utilized in a variety of different ways. Some embodiments utilizing a C—O—H compound to filter a synthesis gas stream. In some embodiments, the C—O—H compound utilized to filter the synthesis gas stream may be utilized to produce additional synthesis gas. The additional synthesis gas may be filtered by additional C—O—H compound. | 04-03-2014 |
20140287333 | CONVERSION OF C-O-H COMPOUNDS INTO HYDROGEN FOR POWER OR HEAT GENERATION - Methods are disclosed for generating electrical power from a compound comprising carbon, oxygen, and hydrogen. Water is combined with the compound to produce a wet form of the compound. The wet form of the compound is transferred into a reaction processing chamber. The wet form of the compound is heated within the reaction chamber such that elements of the compound dissociate and react, with one reaction product comprising hydrogen gas. The hydrogen gas is processed to generate electrical power. | 09-25-2014 |
20150203760 | METHODS, SYSTEMS, AND DEVICES FOR LIQUID HYDROCARBON FUEL PRODUCTION, HYDROCARBON CHEMICAL PRODUCTION, AND AEROSOL CAPTURE - Methods, systems, and devices for liquid hydrocarbon fuel production, hydrocarbon chemical production, and aerosol capture are provided. For example, a carbon-oxygen-hydrogen (C—O—H) compound may be heated to a temperature of at least 800 degrees Celsius such that the C—O—H compound reacts through a non-oxidation reaction to generate at least a hydrocarbon compound that may be at least a component of a liquid hydrocarbon fuel or a hydrocarbon chemical. The liquid hydrocarbon fuel may be a liquid when at a temperature of 20 degrees Celsius. The C—O—H compound may include biomass. In some cases, the hydrocarbon compound produced through the non-oxidation reaction includes a hydrocarbon aerosol form as the hydrocarbon compound at least as it is produced or cools. Some embodiments include aerosol capture methods, systems, and devices, which may include passing a hydrocarbon aerosol form through a material in a liquid phase in order to gather the aerosol material. | 07-23-2015 |