Wang, Edison
Dongye Wang, Edison, NJ US
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20090137467 | Bipartite Inhibitors of Bacterial RNA Polymerase - The invention provides a compound having a structural formula (I): X-α-Y, wherein X is an moiety that binds to the Rif pocket of a bacterial RNA polymerase, Y is a moiety that binds to the secondary channel of a bacterial RNA polymerase, and α is a linker. The compound can act as an inhibitor of bacterial RNA polymerase. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy. | 05-28-2009 |
Guanming Wang, Edison, NJ US
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20110029616 | UNIFIED AUTO-REPLY TO AN EMAIL COMING FROM UNIFIED MESSAGING SERVICE - A system and method for providing an auto-reply message in response to an incoming message sent from a message sending device and delivered by a unified messaging service as an email encoded with information about the sending device's type and address. The incoming messages may be coming from email, fax, phone, text message, instant message, MMS, TV, or other communication devices. The auto-reply function of this invention is capable of replying to the messages regardless of what type of message sending device is used. The system is preferably implemented by integrating the new technologies of unified messaging service and unified message delivery service with the email tool, and by employing the new design methodology of cloud computing. | 02-03-2011 |
Haichao Wang, Edison, NJ US
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20090221542 | Inhibition of Inflammatory Cytokine Production With Tanshinones - Provided are methods of attenuating release of a proinflammatory cytokine from a mammalian cell. Also provided are methods of inhibiting or treating an inflammatory cytokine cascade in a mammal. Further provided are methods of treating a mammal at risk for or undergoing sepsis, septicemia, and/or endotoxic shock. Additionally provided are methods of attenuating NO release from a mammalian cell. Also provided are methods of attenuating NO production in a mammal at risk for, or having, a disorder mediated by excessive NO production. | 09-03-2009 |
20150023957 | SAA DOMAIN-SPECIFIC ANTIBODIES AND PEPTIDE ANTAGONISTS AND USE THEREOF TO TREAT INFLAMMATORY DISEASES - Isolated SAA peptides, fusion proteins and compositions comprising such are provided as are domain-specific SAA antibodies. Methods of treating sepsis and endotoxemia are also provided. | 01-22-2015 |
Huisheng Wang, Edison, NJ US
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20140370019 | BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5, ANTIBODIES SPECIFIC FOR DR5 AND METHODS OF USE - The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 12-18-2014 |
Jun Wang, Edison, NJ US
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20130289003 | DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES - A compound having the structure: useful for treating hypertension, Pulmonary Arterial Hypertension (PAH), congestive heart failure, conditions resulting from excessive water retention, cardiovascular disease, diabetes, oxidative stress, endothelial dysfunction, cirrhosis, pre-eclampsia, osteoporosis or nephropathy. | 10-31-2013 |
Ningjun Wang, Edison, NJ US
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20080281860 | Systems and methods for analyzing documents - Systems and methods are provided for analyzing documents. In one implementation, a computer implemented method is provided for analyzing a patent application and providing a visual representation. According to the method, a selection is received from a user to view claims of the patent application in a claim tree hierarchy and a computer displays the claims in the claim tree hierarchy on a display. The claim tree hierarchy visually depicts relationships between the claims. The method identifies one or more words of at least one of the claims that constitutes an element and displays, in the claim tree hierarchy, the words constituting the element in association with the claim. | 11-13-2008 |
Norton Wang, Edison, NJ US
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20130132294 | System and Method for Engaging a Social Network - A method of engaging a consumer's social network includes promoting a potential gift to members of the consumer's social network, soliciting and receiving contributions to the gift from members of the consumer's social network, and determining whether a trigger condition has been met. The method then provides a gift to the consumer, and the gift may include one or more conditional contributions from the vendor of the gift item, depending on the whether the trigger condition has been met. | 05-23-2013 |
Suke Wang, Edison, NJ US
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20090075297 | MAMMALIAN GALANIN RECEPTORS - The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors. | 03-19-2009 |
20090176254 | MAMMALIAN GALANIN RECEPTORS - The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors. | 07-09-2009 |
Wearn-Juhn Wang, Edison, NJ US
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20110045794 | DOCKING UNIT AND VEHICLE POWER ADAPTER WITH FREQUENCY MODULATED AUDIO SIGNAL INJECTION FOR CONNECTING PORTABLE MEDIA PLAYER AND/OR COMMUNICATIONS DEVICE TO VEHICLE FM RADIO AND AUDIO SYSTEM FOR PLAYBACK OF DIGITAL AUDIO BROADCAST STREAM - A cigarette lighter adapter (CLA) is provided with a main body configured to be connected at one end thereof to a vehicle cigarette lighter socket or auxiliary power socket. The main body of the cigarette lighter adapter is also connected to one end of a coaxial cable. The other end of the coaxial cable is preferably terminated with a standard low cost DC connector for connection to a portable media player (e.g., with integrated or separate satellite radio receiver) or other content source that provides a frequency modulated (FM) radio frequency signal with audio content onto the coaxial cable | 02-24-2011 |
Wenyan Wang, Edison, NJ US
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20080199447 | CATALYTIC DOMAIN OF ADAM33 AND METHODS OF USE THEREOF - The present invention discloses purified polypeptides that comprise an active ADAM33 catalytic domain. In addition, the present invention discloses nucleic acids that encode the polypeptides of the present invention. The present invention also discloses methods of growing X-ray diffractable crystals of polypeptides comprising the active ADAM33 catalytic domain. In addition, the present invention discloses methods of using the X-ray diffractable crystals of ADAM33 in structure-based drug design to identify compounds that can modulate the enzymatic activity of ADAM33. The present invention also discloses methods of treating respiratory disorders by administering therapeutic amounts of the ADAM33 catalytic domain. | 08-21-2008 |
20100203616 | REFOLDED RECOMBINANT ALPHA SECRETASE CRYSTALS AND METHODS FOR PREPARING AND USING THE SAME - The present application relates to methods for growing crystals of both the uncomplexed and complexed forms of β-secretase (BACE) polypeptide. The present application also relates to crystalline forms of uncomplexed BACE and the three-dimensional structure of BACE, as determined from the crystals. In addition, the present application relates to the use of crystalline forms of BACE to identify ligands, preferably inhibitors (antagonists), which bind to, and preferably inhibit the enzymatic activity of, BACE. Furthermore, the present application relates to nucleic acid sequences encoding BACE polypeptide, and methods for making BACE in greater quantity than prior methods, resulting in more effective crystallization. | 08-12-2010 |
20100286372 | Pregnane X Receptor Compositions, Crystals and Uses Thereof - The present invention relates, inter alia, to PXR polypeptides and crystals that are useful, for example, for crystallization and in assays for identification of modulators of PXR. | 11-11-2010 |
Yaolin Wang, Edison, NJ US
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20110104256 | METHODS FOR TREATING OR PREVENTING COLORECTAL CANCER - The present invention provides, for example, methods for treating or preventing colorectal cancer with an anti-IGF1R antibody in association with sunitinib or a combination of leucovorin and 5-fluorouracil. | 05-05-2011 |
20110129456 | Sequential Administration of Chemotherapeutic Agents for Treatment of Cancer - The present invention relates to the sequential administration of a cytotoxic agent followed by an IGF1R antagonist (e.g., an antibody) for the treatment of hyperproliferative disorders including cancer. | 06-02-2011 |
Zaiqi Wang, Edison, NJ US
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20130096457 | ORAL SCOPE SYSTEM WITH IMAGE SENSOR AND METHOD FOR VISUAL EXAMINATION OF ORAL CAVITY AND UPPER AIRWAY - An oral scope instrument for facilitating visual examination and inspection of a person's oral cavity and upper airway includes an elongate, flexible arm having first and second ends, a temperature sensor connected to the flexible arm adjacent the first end, an image sensor mounted adjacent the second end, a processor in electrical communication with the image sensor and an image display device. An illumination unit located adjacent the second end provides illumination for the image sensor. A handle connected to the first end enables manual insertion of the flexible arm into the mouth along a portion of the top of the tongue to engage the temperature sensor therewith and position the image sensor for viewing and recording anatomical features of the oral cavity or the upper airway. The processor stores normal anatomical images and may transmit images of recorded anatomical features to the image display device. | 04-18-2013 |