Patent application number | Description | Published |
20100222318 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 09-02-2010 |
20120027874 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 02-02-2012 |
20120035408 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 02-09-2012 |
20120040020 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present disclosure relates to pyrazine compounds of formula I: | 02-16-2012 |
20120122884 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 05-17-2012 |
20140113005 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present disclosure relates to pyrazine compounds of formula I: | 04-24-2014 |
20150031661 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 01-29-2015 |
20150051187 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 02-19-2015 |
Patent application number | Description | Published |
20120084629 | Systems and Methods for Generating Sitelets Using Information Assets - A definition of an information category a user wishes to publish to the Internet is received from a user. At least one information asset comprising a link to an information data object is received and assigned to the information category. Sitelet generation parameters are received from the user, including a sitelet category comprising the information category, and optionally, other sitelet generation parameters such as data feed types and additional information categories. A sitelet is then generated using the sitelet category and any other supplied sitelet generation parameters. The sitelet comprises a data feed of a first data feed type comprising a representation of the information assets assigned to the sitelet category and any additional information categories. The data feed type can be in any standard format, such as RSS or ATOM, or any custom format, such as iFrame HTML, XML or JSON. If the user specifies more than one data feed type, sitelets are generated for each data feed type. | 04-05-2012 |
20130185352 | SYSTEMS, COMPUTER PROGRAM PRODUCTS, AND METHODS FOR GENERATING CUSTOM WEB PAGES FOR MOBILE DEVICE - A system generating a web page portal customized for a particular requesting mobile device is disclosed. The system includes an information store having multiple groups, each associated with device qualifications, web-design characteristics, and device identifications. The system also includes a custom web page development database (CWDD) including a plurality of web page component modules storing forms of web page components, and a custom web page development server (CWDS). The CWDS (i) receives an incoming request for a web page from the particular requesting mobile device, (ii) identifies a device type, and (iv) determines an applicable group. The CWDS also (v) obtains web-design characteristics from the applicable group, (vi) accesses the CWDD and obtains applicable web page components based on the web-design characteristics obtained from the applicable group of the information store, and (vii) generates the custom web page portal using the applicable web page components obtained from the CWDD. | 07-18-2013 |
20150095766 | Systems, Computer Program Products, and Methods for Generating Custom Web Pages for Mobile Device - A system generating a web page portal customized for a particular requesting mobile device is disclosed. The system includes an information store having multiple groups, each associated with device qualifications, web-design characteristics, and device identifications. The system also includes a custom web page development database (CWDD) including a plurality of web page component modules storing forms of web page components, and a custom web page development server (CWDS). The CWDS (i) receives an incoming request for a web page from the particular requesting mobile device, (ii) identifies a device type, and (iv) determines an applicable group. The CWDS also (v) obtains web-design characteristics from the applicable group, (vi) accesses the CWDD and obtains applicable web page components based on the web-design characteristics obtained from the applicable group of the information store, and (vii) generates the custom web page portal using the applicable web page components obtained from the CWDD. | 04-02-2015 |