Patent application number | Description | Published |
20150378774 | LOG-BASED CONCURRENCY CONTROL USING SIGNATURES - A transaction request is received at a log-based transaction manager, indicating a conflict check delimiter and a read set descriptor indicative of one or more locations from which data is read during the requested transaction. Using the conflict check delimiter, a subset of transaction records stored in a particular persistent log to be examined for conflicts prior to committing the requested transaction is identified. In response to determining that none of the read locations of the requested transaction correspond to a write location indicated in the subset of transaction records, a new transaction record is stored in the particular persistent log indicating that the requested transaction has been committed. | 12-31-2015 |
20150378775 | LOG-BASED TRANSACTION CONSTRAINT MANAGEMENT - A transaction request is received at a log-based transaction manager, indicating a logical constraint to be satisfied before the corresponding transaction is committed. The transaction manager identifies a subset of transaction records stored in a persistent change log that are to be examined to evaluate the logical constraint. Based at least in part on the result of a comparison of one or more constraint-related data signatures included in the transaction request with corresponding data signatures in the subset of transaction records, a decision is made to commit the requested transaction. | 12-31-2015 |
20150379062 | MULTI-DATABASE LOG WITH MULTI-ITEM TRANSACTION SUPPORT - At a logging service, a representation of a transaction requested by a client is received. The transaction includes at least a first write operation directed to a data object at a first data store. Based at least in part on the contents of the representation and contents of a persistent log of the logging service, a determination is made that the requested transaction is to be committed. A log record corresponding to the first write operation is inserted into the persistent log. The first write is propagated to the first data store after the record has been inserted in the persistent log. | 12-31-2015 |
20150379099 | DISTRIBUTED STATE MANAGEMENT USING DYNAMIC REPLICATION GRAPHS - A sequence of configuration-delta messages from a configuration manager of a replication graph established for replicating state information of an application is received at a particular node of the graph. Representations of the messages are stored in a local configuration change repository. Using the repository, the node identifies neighbor source nodes and destination nodes of the graph. Subsequent to receiving a particular configuration-delta message indicating that a neighbor source node has been removed from the graph, a different source node is identified by the particular node, and a request is sent to the different source node to transmit a set of state transition messages pertaining to the application. | 12-31-2015 |
20150379100 | COORDINATED SUSPENSION OF REPLICATION GROUPS - A target commit sequence number (CSN) to be used to synchronize state information pertaining to an application among nodes of a state replication group (SRG) prior to a suspension of the SRG's operations is identified. Each node stores a respective commit record set of the application. Some number of SRG nodes suspend operations after synchronizing their local commit records up to the CSN. A configuration manager of the SRG verifies that, subsequent to a suspension of operations at the nodes, at least a threshold number of the nodes are available for service and have updated their commit record sets. The configuration manager then re-activates the SRG. | 12-31-2015 |
Patent application number | Description | Published |
20090209626 | Duplex Oligonucleotides with Enhanced Functionality in Gene Regulation - Disclosed are methods of enhancing functionality of duplex oligonucleotides and compositions made by the methods. The duplex oligonucleotides include siRNAs, miRNA mimics, and piRNA mimics which contain modified nucleotides and mismatches between the two strands of the molecule at specific nucleotide positions. | 08-20-2009 |
20100184209 | COMPOSITIONS AND METHODS FOR INHIBITING GENE SILENCING BY RNA INTERFERENCE - The present invention provides compositions and methods for inhibiting gene silencing by the RNAi pathway. The RNAi inhibitors of the invention have a reverse complement (RC) region to the target molecule of interest (e.g., miRNA) in association with at least one flanking region coupled to either at the 3′ or 5′ end of the RC region. The flanking regions can be single-stranded or can have one or more regions of double stranded nucleic acid with or without a hairpin loop. The RNAi inhibitors described herein can inhibit endogenous targets, including but not limited to microRNAs, or piRNAs, or can be used to inhibit the effects of exogenously introduced molecules, such as synthetic siRNAs, siRNAs expressed from vector constructs (e.g., viral expression systems), or siRNAs generated by enzymatic methods. Inhibition is specific, potent, prolonged, and can be performed on a single target or multiple targets simultaneously. | 07-22-2010 |
20100273856 | SCREENING OF MICRO-RNA CLUSTER INHIBITOR POOLS - The disclosure provides methods for inhibiting the activity of a miRNA cluster in a cell, and also for screening a cell for a phenotype(s) of interest resulting from inhibition of a miRNA cluster. The methods use a cluster pool which comprises at least one miRNA inhibitor specific for each miRNA in the miRNA cluster. MiRNA inhibitors are described that induce apoptosis in breast cancer cells and hence are useful in the treatment of breast cancer. The disclosure also provides pharmaceutical compositions which are useful for the treatment of breast cancer; methods for inducing the nuclear translocation of NF-κB in a breast cancer cell; methods for inducing the nuclear translocation of c-Jun in a breast cancer cell; method for inhibiting the nuclear translocation of NF-κB in a breast cancer cell; and methods for providing prognostic medical information relating to breast cancer progression. | 10-28-2010 |
20110172289 | MINOR GROOVE BINDER (MGB)-OLIGONUCLEOTIDE MIRNA ANTAGONISTS - Compositions and methods for inhibiting the actions of non-coding RNAs such as miRNAs and piRNAs are provided. The compositions comprise single or double stranded oligonucleotides conjugated with Minor Groove Binders (“MGBs”). The oligonucleotides can vary in length, can contain nucleotides having one or more modifications, and have regions that are substantially complementary to one or more mature miRNAs or piRNAs. | 07-14-2011 |
20120245219 | MINOR GROOVE BINDER (MGB)-OLIGONUCLEOTIDE MIRNA ANTAGONISTS - Compositions and methods for inhibiting the actions of non-coding RNAs such as miRNAs and piRNAs are provided. The compositions comprise single or double stranded oligonucleotides conjugated with Minor Groove Binders (“MGBs”). The oligonucleotides can vary in length, can contain nucleotides having one or more modifications, and have regions that are substantially complementary to one or more mature miRNAs or piRNAs. | 09-27-2012 |
20120259001 | Duplex Oligonucleotides with Enhanced Functionality in Gene Regulation - Disclosed are methods of enhancing functionality of duplex oligonucleotides and compositions made by the methods. The duplex oligonucleotides include siRNAs, miRNA mimics, and piRNA mimics which contain modified nucleotides and mismatches between the two strands of the molecule at specific nucleotide positions. | 10-11-2012 |
20150353927 | Templates, Libraries, Kits and Methods for Generating Molecules - The present invention is directed to collections of templates for molecules such as RNA, as well as templates, devices, kits and methods for generating molecules from these collections. Through the use of various embodiments of the present invention one may efficiently and effectively obtain selected RNA molecules such as siRNA, shRNA, miRNA mimics and inhibitors, lncRNA, antisense RNA, aptamers, ribozymes, and sgRNA and sets of those molecules. | 12-10-2015 |
Patent application number | Description | Published |
20130308898 | CO-PACKAGING PHOTONIC INTEGRATED CIRCUITS AND APPLICATION SPECIFIC INTEGRATED CIRCUITS - Disclosed herein are designs, structures and techniques for advanced packaging of multi-function photonic integrated circuits that allow such high-performance multi-function photonic integrated circuits to be co-packaged with a high-performance multi-function ASIC thereby significantly reducing strenuous interconnect challenges and lowering costs, power and size of the overall devices. | 11-21-2013 |
20130343705 | CLADDING DEFINED TRANSMISSION GRATING - Disclosed herein are techniques, methods, structures and apparatus for providing photonic structures and integrated circuits with optical gratings disposed within cladding layer(s) of those structures and circuits. | 12-26-2013 |
20140064659 | ELECTRONIC AND OPTICAL CO-PACKAGING OF COHERENT TRANSCEIVER - Disclosed herein are co-packaging structures, devices, and methods for integrating a photonic integrated circuit (PIC), an electronic integrated circuit including drivers and transimpedance amplifiers (TIAs) and an ASIC having analog-to-digital converters and a digital signal processor positioned on a common (the same) carrier thereby resulting in a compact coherent transceiver while lowering its cost. | 03-06-2014 |
20140112611 | ROBUST MODULATOR CIRCUITS USING LATERAL DOPING JUNCTIONS - Disclosed herein are methods, structures, and devices that compensates for modulator loss and modulation inefficiencies introduced by mask misalignments in opposite oriented pn type junction modulators. More specifically, Mach-Zehnder type optical modulators are disclosed wherein both arms in the MZI modulator are arranged in a push-pull configuration and configured to experience pn type junctions of two orientations wherein both arms further configured to experience the same length of waveguide with a pn type junction of each orientation. | 04-24-2014 |
20150063747 | FIBER ASSEMBLY FOR FACET OPTICAL COUPLING - Disclosed are structures and methods for facet optical coupling of optical fibers to photonic integrated circuits. | 03-05-2015 |
20150132013 | ADVANCED OPTICAL MODULATION GENERATION BY COMBINING ORTHOGONAL POLARIZED OPTICAL SIGNALS - Disclosed are adaptive structures and methods for generating advanced modulation formats using multiple levels such as PAM-4, PAM-8 as well as regular OOK or PM OOK formats. Structures and methods disclosed include an unequal power splitter that may exhibit a fixed or tunable splitting ratio such that adaptive format(s) may be generated. | 05-14-2015 |
20150214122 | WAFER-SCALE TESTING OF PHOTONIC INTEGRATED CIRCUITS USING HORIZONTAL SPOT-SIZE CONVERTERS - Disclosed herein are methods, structures, and devices for wafer scale testing of photonic integrated circuits. | 07-30-2015 |
Patent application number | Description | Published |
20150193284 | HOST/HOSTED HYBRID APPS IN MULTI-OPERATING SYSTEM MOBILE AND OTHER COMPUTING DEVICES - According to further aspects of the invention, there is provided a computing device that executes a hybrid application in a single application address space established within a runtime environment defined under a native operating system executing on the device. That hybrid application includes (i) instructions comprising a “hosted” software application built and intended for execution under an operating system that differs from the native operating system, i.e., a hosted operating system, and (ii) instructions from at least one of a runtime library and another resource of the native runtime environment. | 07-09-2015 |
20150193285 | HOSTED APP INTEGRATION SERVICES IN MULTI-OPERATING SYSTEM MOBILE AND OTHER COMPUTING DEVICES - The invention provides, in some aspects, a computing device that includes a central processing unit that is coupled to a hardware interface and that executes a native operating system including one or more native runtime environments within which native software applications are executing. A first native software application executing within the one or more native runtime environments defines one or more hosted runtime environments within which hosted software applications are executing. One or more further native software applications (“IO proxies”), each executing within the one or more native runtime environments and each corresponding to a respective one of the one or more hosted software applications, receives the graphics generated by the respective hosted software application and effects writing of those graphics to the video frame buffer for presentation on the display of the computing device. | 07-09-2015 |
20150193904 | GRAPHICS ACCELERATION FOR APPLICATIONS EXECUTING ON MOBILE DEVICES WITH MULTI-OPERATING SYSTEM ENVIRONMENT - The invention provides, in some aspects, a computing device that includes a central processing unit, a graphics processing unit, and a display, all coupled (directly or indirectly for communications). The central processing unit executes a native operating system including one or more native runtime environments within which native software applications are executing, where each such native software application has instructions for execution under the native operating system. A first native software application (“ACL”) executing within one or more of the native runtime environments defines one or more hosted runtime environments within which hosted software applications are executing. Thus, for example, according to some practices of the invention, the first native software application executes code comprising those hosted runtime environment or portions thereof (such as virtual machines); whereas, in other practices, the first native software application can, instead or in addition, effect the installation, instantiation and/or invocation of services/processes that make up those environments or portions thereof (but, indeed, may not in some practices execute code comprising that environment). Each such hosted software application has instructions for execution under a hosted operating system that differs from the native operating system. Hosted software applications executing within the hosted runtime environment(s) execute instructions to effect generation of three-dimensional display graphics using a hosted graphics subsystem and a hosted windowing subsystem (collectively, “hosted graphics framework”), both common to the hosted runtime environment(s). Native software applications executing within the native runtime environment(s) likewise effect generation of three-dimensional display graphics using a native graphics subsystem and a native windowing subsystem (collectively, “native graphics framework”), also, both common to the native runtime environment(s). The three-dimensional graphics can be, for example, graphical windows (or portions thereof) representing visual sequences of games or other graphics applications. The native graphics framework is coupled to the graphics processing unit to accelerate execution of at least certain instructions in the native software applications. The hosted graphics framework and the native graphics framework cooperate to accelerate execution of at least certain instructions in the hosted software applications using the graphics processing unit. | 07-09-2015 |
Patent application number | Description | Published |
20110166855 | Systems and Methods for Hands-free Voice Control and Voice Search - In one embodiment the present invention includes a method comprising receiving an acoustic input signal and processing the acoustic input signal with a plurality of acoustic recognition processes configured to recognize the same target sound. Different acoustic recognition processes start processing different segments of the acoustic input signal at different time points in the acoustic input signal. In one embodiment, initial states in the recognition processes may be configured on each time step. | 07-07-2011 |
20130054235 | TRULY HANDSFREE SPEECH RECOGNITION IN HIGH NOISE ENVIRONMENTS - Embodiments of the present invention improve content manipulation systems and methods using speech recognition. In one embodiment, the present invention includes a method comprising configuring a recognizer to recognize utterances in the presence of a background audio signal having particular audio characteristics. A composite signal comprising a first audio signal and a spoken utterance of a user is received by the recognizer, where the first audio signal comprises the particular audio characteristics used to configure the recognizer so that the recognizer is desensitized to the first audio signal. The spoke utterance is recognized in the presence of the first audio signal when the spoken utterance is one of the predetermined utterances. An operation is performed on the first audio signal. | 02-28-2013 |
20140180691 | SYSTEMS AND METHODS FOR HANDS-FREE VOICE CONTROL AND VOICE SEARCH - In one embodiment the present invention includes a method comprising receiving an acoustic input signal and processing the acoustic input signal with a plurality of acoustic recognition processes configured to recognize the same target sound. Different acoustic recognition processes start processing different segments of the acoustic input signal at different time points in the acoustic input signal. In one embodiment, initial states in the recognition processes may be configured on each time step. | 06-26-2014 |
20140195236 | SPEAKER VERIFICATION AND IDENTIFICATION USING ARTIFICIAL NEURAL NETWORK-BASED SUB-PHONETIC UNIT DISCRIMINATION - In one embodiment, a computer system stores speech data for a plurality of speakers, where the speech data includes a plurality of feature vectors and, for each feature vector, an associated sub-phonetic class. The computer system then builds, based on the speech data, an artificial neural network (ANN) for modeling speech of a target speaker in the plurality of speakers, where the ANN is configured to discriminate between instances of sub-phonetic classes uttered by the target speaker and instances of sub-phonetic classes uttered by other speakers in the plurality of speakers. | 07-10-2014 |
20150261944 | UNOBTRUSIVE VERIFICATION OF USER IDENTITY - Techniques for unobtrusively verifying the identity of a user of a computing device are provided. In one embodiment, the computing device can establish one or more verification models for verifying the user's identity, where at least a subset of the one or more verification models is based on enrollment data that is collected in an unobtrusive manner from the user. The computing device can then verify the user's identity using the one or more verification models. | 09-17-2015 |
20150317980 | ENERGY POST QUALIFICATION FOR PHRASE SPOTTING - In one embodiment, a computing device can detect an utterance of a target phrase within an acoustic input signal. The computing device can further determine a first estimate of cumulative signal and noise energy for the detected utterance in the acoustic input signal with respect to a first time period spanning the duration of the detected utterance, and a second estimate of noise energy in the acoustic input signal with respect to a second time period preceding (or following) the first time period. The computing device can then calculate a signal-to-noise ratio (SNR) for the detected utterance based on the first and second estimates and can reject the detected utterance if the SNR is below an SNR threshold. | 11-05-2015 |
Patent application number | Description | Published |
20090010816 | APPARATUS AND METHOD FOR CONTROLLED COMBUSTION OF GASEOUS POLLUTANTS - The present invention relates to systems and methods for controlled combustion of gaseous pollutants while reducing and removing deposition of unwanted reaction products from within the treatment systems. The systems employ a two-stage thermal reactor having an upper thermal reactor including at least one inlet for mixing a gaseous waste stream with oxidants and combustible fuels for thermal combustion within the upper thermal reactor. The upper thermal reactor further includes a double wall structure having an outer exterior wall and an interior porous wall that defines an interior space for holding a fluid and ejecting same, in a pulsating mode, through the interior porous wall into the upper thermal reactor to reduce deposition of the reaction products on the interior of the upper reactor chamber. The two-stage thermal reactor further includes a lower reactor chamber for flowing reaction products formed in the upper thermal reactor through a water vortex that provides a water overflow along the interior of the lower reactor chamber thereby reducing deposition of unwanted products on the interior surface of the lower reactor. | 01-08-2009 |
20090078656 | APPARATUS AND METHODS FOR AMBIENT AIR ABATEMENT OF ELECTRONIC DEVICE MANUFACTURING EFFLUENT - An abatement system is provided which includes 1) an abatement unit adapted to abate effluent; and 2) an ambient air supply system comprising an air moving device, wherein the ambient air supply system is adapted to supply ambient air to the abatement unit for use as an oxidant. Numerous other aspects are provided. | 03-26-2009 |
20140205882 | LI-ION POUCH CELL AND A CELL MODULE - The present invention provides a Li-ion pouch cell wherein the Li-ion pouch cells comprise a sealed enclosure, electrode stack and thermally conductive elements, wherein the electrode stack and the thermally conductive elements are in the sealed enclosure, the thermally conductive elements include extensions which extend beyond the electrode stack, the sealed enclosure has thermal conductivity, the thermally conductive elements provide a thermally conductive pathway connecting the electrode stack and the sealed enclosure by way of the extension. The present invention also provides a cell module comprising the Li-ion pouch cells. The Li-ion pouch cell and the cell module according to the present application could minimize differences in cell temperature, monitor internal cell temperature, cool the cell rapidly, increase cell and module safety, allowing for minimal impact on cell energy density, performance or life and difficulty of manufacturing. | 07-24-2014 |
20150311514 | PRECURSOR OF LI-ION CATHODE MATERIAL, THE PREPARATION METHOD THEREOF AND LI-ION CATHODE MATERIAL - Li-ion cathode materials with improved performance characteristics and precursors to prepare such materials are disclosed. The precursors consist of complex, mixed alkali transition metal oxides of the formula Li | 10-29-2015 |
Patent application number | Description | Published |
20080236778 | Wire injection lance nozzle insert - A lance nozzle insert for a refractory lance for feeding an additive wire into a quantity of molten metal below the surface of the molten metal surface is made of a material comprising stabilized zirconium oxide and graphite substantially increasing the corrosion resistance of the lance nozzle insert. | 10-02-2008 |
20090047425 | Calcium Enriched Refractory Material by the Addition of Calcium Carbonate - The composition applied to the refractory structure has a magnesia-based refractory material, calcium carbonate and a binder. After application of the refractory material to a refractory structure and upon application of heat to the applied refractory material a matrix is formed which protects against penetration of the slag into the refractory material. The resulting refractory material has improved hot strength, slag resistance and durability. | 02-19-2009 |
20090057964 | Rotary lance - A process and apparatus for feeding an additive to a molten metal in a vessel to achieve a uniform dispersion of the additive are provided. In one example, the outlet of the lance is positioned below the surface of the molten metal. The lance is moved with a reciprocating motion, so that the outlet of the lance moves below the surface of the molten metal. The additive is dispensed through the outlet of the lance along a path traversed by the outlet in the molten metal while the lance reciprocates. | 03-05-2009 |
20100007067 | WIRE INJECTION LANCE NOZZLE ASSEMBLY - A lance nozzle tip for a refractory lance for feeding an additive wire into a quantity of molten metal below the surface of the molten metal surface has a refractory casing and a conduit located within the refractory casing. The refractory casing has a nozzle portion which has a lance nozzle insert. The conduit has a first portion in the nozzle portion and a main portion having a second portion of the conduit. The first portion of the conduit has a passage extending from an inlet end of the first portion of the conduit to an outlet end of the first portion of the conduit. The passage has a diameter for a substantial portion of the length of the first portion of the conduit and a funnel-shaped portion at the inlet end of the first portion of the conduit for guiding the additive wire conveyed through the passage and second portion of the conduit. | 01-14-2010 |
20100189896 | CALCIUM ENRICHED REFRACTORY MATERIAL BY THE ADDITION OF CALCIUM CARBONATE - The composition applied to the refractory structure has a magnesia-based refractory material, calcia source and a binder. After application of the refractory material to a refractory structure and upon application of heat to the applied refractory material a matrix is formed which protects against penetration of the slag into the refractory material. The resulting refractory material has improved hot strength, slag resistance and durability. | 07-29-2010 |
20140322442 | CALCIUM ENRICHED REFRACTORY MATERIAL BY THE ADDITION OF CALCIUM CARBONATE - The composition applied to the refractory structure has a magnesia-based refractory material, calcia source and a binder. After application of the refractory material to a refractory structure and upon application of heat to the applied refractory material a matrix is formed which protects against penetration of the slag into the refractory material. The resulting refractory material has improved hot strength, slag resistance and durability. | 10-30-2014 |