| Patent application number | Description | Published |
| 20080200821 | LEFT ATRIAL ACCESS APPARATUS AND METHODS - Left atrial access apparatus and methods are described herein. Different parameters, such as oxygen saturation difference, between the left and right atrial chambers is utilized to guide a needle or catheter into a desired position within the heart. Various sensing elements can be utilized to detect the physiological parameter difference, such as oxygen levels, in the left atrium. The sensor can be carried by the needle, at its tip or along its body, and can measure the physiological parameter levels contained in the blood, fluid, or tissue. | 08-21-2008 |
| 20080200930 | APPARATUS FOR MANIPULATING AND SECURING TISSUE - Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to a longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body. | 08-21-2008 |
| 20080214889 | METHODS AND APPARATUS FOR PREVENTING TISSUE MIGRATION - Methods and apparatus for preventing tissue migration or tissue “tenting” during transseptal access procedures are described. The underlying tissue wall may be temporarily engaged via any number of mechanisms, e.g., engaging teeth or projections, threaded needle, vacuum, etc., and one or more instruments may be passed through the tissue wall while maintaining engagement with the tissue to provide a counter-traction force. The procedure may be accomplished while under direct visualization within an imaging hood placed against the tissue surface and purged of blood. | 09-04-2008 |
| 20080275300 | COMPLEX SHAPE STEERABLE TISSUE VISUALIZATION AND MANIPULATION CATHETER - Complex shape steerable tissue visualization and manipulation catheters and their methods of use of disclosed herein. The deployment catheter may be articulated utilizing various steering mechanisms to adjust a position of a visualization hood or membrane through which underlying tissue may be visualized. | 11-06-2008 |
| 20080281293 | COMPLEX SHAPE STEERABLE TISSUE VISUALIZATION AND MANIPULATION CATHETER - Complex steerable catheter visualization and tissue manipulation systems and their methods of use are disclosed herein. The deployment catheter is articulated using various steering mechanisms. Tissue visualization is accomplished from the visualization hood at the distal end of the deployment catheter, the hood having an ability to expand and other features to facilitate visualization and articulation at the tissue surface. | 11-13-2008 |
| 20090082623 | Visualization and treatment via percutaneous methods and devices - Visualization and treatment of tissue regions via percutaneous access methods and devices are described herein. The system may include a deployment catheter and an expandable imaging hood. In use, the hood may be introduced from outside the patient body through a percutaneous incision and advanced through a subxiphoid pathway, for example, to the heart where entry may be accomplished via an incision through the left atrial appendage. Once within the heart, the hood can be advanced to any chamber to visualize and/or treat tissue by placing the hood against the tissue to be imaged and pumping translucent fluids into the hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for treating the tissue of interest. | 03-26-2009 |
| 20090275842 | STABILIZATION OF VISUALIZATION CATHETERS - Systems for the stabilization of visualization catheters are described herein which facilitate the deployment and retraction of an imaging hood from a catheter. Such systems may include a deployment catheter and an imaging hood having one or more structural elements which may be integrated or advanced into the hood independently of the hood itself. Moreover, additional features such as rapid exchange ports may be integrated along the hood or along the catheter proximal to the hood to facilitate intravascular procedures and treatments. | 11-05-2009 |
| 20090281433 | SYSTEMS AND METHODS FOR PULMONARY MONITORING AND TREATMENT - Systems and methods are disclosed determining a pulmonary function by mounting one or more sensors intra-orally; capturing intra-oral data; and determining the pulmonary function based on an analysis of the intra-oral data. | 11-12-2009 |
| 20090299363 | OFF-AXIS VISUALIZATION SYSTEMS - Off-axis visualization systems are described herein which facilitate the deployment, visualization, and retraction of an imaging element from a catheter. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration as well as an imaging element, such as a CCD or CMOS imager, which may be deployed from a low profile configuration into a position which is off-axis relative to a longitudinal axis of the deployment catheter and/or imaging hood. | 12-03-2009 |
| 20100249766 | METHODS AND APPARATUS FOR CRYO-THERAPY - Methods and apparatus for cryo-therapy are disclosed herein. This includes a hollow guidewire disposed within a catheter having helical loops contacting tissue. A coolant delivery tube disposed within can have a coolant delivered from a proximal end into the guidewire lumen. The coolant flows back proximally through the guidewire while cooling the guidewire surface and cooling or cryogenically ablating the contacting tissue. To minimize guidewire exposure to surrounding fluids or tissue, insulative barriers can be attached to the guidewire. A coolant delivery tube and return lumen can be integrated from a single extrusion in various configurations. Expandable balloons can also be used to expand the loops of the guidewire to contact the tissue. Also, helical loops with a coolant delivery tube or stem disposed longitudinally within the loops can be used and the loops can also have a variable collapsible cooling region. | 09-30-2010 |
| 20110060314 | DEVICES AND METHODS FOR TREATING TISSUE - Described herein are devices, systems and methods for treating target tissue in a patient's spine. In general, the methods include the steps of advancing a wire into the patient from a first location, through a neural foramen, and out of the patient from a second location; connecting a tissue modification device to the wire; positioning the tissue modification device through the neural foramen using the wire; modifying target tissue in the spine by moving the tissue modification device against the target tissue; and delivering an agent to modified target tissue, wherein the agent is configured to inhibit blood flow from the modified target tissue. In some embodiments, the step of modifying target tissue comprises removing target tissue located ventral to the superior articular process while avoiding non-target tissue located lateral to the superior articular process. | 03-10-2011 |
| 20110098708 | POWERED TISSUE MODIFICATION DEVICES AND METHODS - A device for modifying tissue in a spine may include: a shaft having a proximal portion and a distal portion, the distal portion having dimensions which allow it to be passed into an epidural space of the spine and between target and non-target tissues; at least one distal force application member extending from the distal portion of the shaft and configured to facilitate application of at least one of anchoring force and tensioning force to the shaft; at least one movable tissue modifying member coupled with the shaft at or near its distal portion; at least one drive member coupled with the at least one tissue modifying member to activate the at least one tissue modifying member; and at least one power transmission member coupled with the at least one drive member to deliver power to the at least one drive member. | 04-28-2011 |
| 20110160731 | DEVICES AND METHODS FOR TISSUE ACCESS - Methods and apparatus are provided for selective surgical removal of tissue, e.g., for enlargement of diseased spinal structures, such as impinged lateral recesses and pathologically narrowed neural foramen. In some embodiments, a surgical tissue removal device includes a flexible elongate body that is adapted to conform with the target anatomy and a guidewire connector at the distal end region of the flexible elongate body configured to removably connect to the end of a guidewire so that the guidewire and flexible elongate body can be pulled distally. The body may have at least one blade edge, and the flexible elongate body may be a thin, flat, ribbon shaped flexible body that comprises a profile having a width that is substantially greater than a height. | 06-30-2011 |