| Patent application number | Description | Published |
| 20090142765 | METHOD AND APPARATUS FOR RAPIDLY COUNTING AND IDENTIFYING BIOLOGICAL PARTICLES IN A FLOW STREAM - A method for increasing the throughput, or the precision, or both the precision and the throughput, of a flow cytometer, or of a hematology analyzer employing a flow cytometer, and for further reducing the complexity of such a cytometer or analyzer, by utilizing the technique of laser rastering in combination with a lysis-free single-dilution method. Laser rastering involves sweeping a laser beam across a flowing sample stream in a hematology analyzer. A lysis-free single-dilution method involves performing all the flow cytometer measurements on a sample using a single aliquot, a single lysis-free reagent solution, a single dilution, and a single pass of said dilution through the measurement apparatus. An apparatus suitable for carrying out the method of this invention comprises an optical module comprising a source of light, a scanning device, a lens or system of lenses, a flowcell, detectors, and filters; and an electronic module comprising preamplifiers, analog signal conditioning elements, analog-to-digital converters, field-programmable gate arrays, digital signal processing elements, and data storage elements. | 06-04-2009 |
| Patent application number | Description | Published |
| 20100273168 | METHOD FOR DISCRIMINATING RED BLOOD CELLS FROM WHITE BLOOD CELLS BY USING FORWARD SCATTERING FROM A LASER IN AN AUTOMATED HEMATOLOGY ANALYZER - A method for identifying, analyzing, and quantifying the cellular components of whole blood by means of an automated hematology analyzer and the detection of the light scattered, absorbed, and fluorescently emitted by each cell. More particularly, the aforementioned method involves identifying, analyzing, and quantifying the cellular components of whole blood by means of a light source having a wavelength ranging from about 400 nm to about 450 nm and multiple in-flow optical measurements and staining without the need for lysing red blood cells. | 10-28-2010 |
| 20100328662 | METHOD AND APPARATUS FOR RAPIDLY COUNTING AND IDENTIFYING BIOLOGICAL PARTICLES IN A FLOW STREAM - A method for increasing the throughput, or the precision, or both the precision and the throughput, of a flow cytometer, or of a hematology analyzer employing a flow cytometer, by utilizing the technique of laser rastering. Laser rastering involves sweeping a laser beam across a flowing sample stream in a hematology analyzer. An apparatus suitable for carrying out the method of this invention comprises an optical module comprising a source of light, a scanning device, a lens or system of lenses, a flow cell, detectors, and filters; and an electronic module comprising preamplifiers, analog signal conditioning elements, analog-to-digital converters, field-programmable gate arrays, digital signal processing elements, and data storage elements. | 12-30-2010 |
| 20110045525 | Method for Flagging a Sample - A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells. | 02-24-2011 |
| 20110178716 | Method for determining volume and hemoglobin content of individual red blood cells - Provided herein is a method for determining the volume or hemoglobin content of an individual red blood cell in a sample containing a population of red blood cells. The method may be performed on a hematology analyzer. Also provided are a hematology analyzer for performing the method and a computer-readable medium containing programming for performing the method. | 07-21-2011 |
| 20110228271 | METHOD AND APPARATUS FOR RAPIDLY COUNTING AND IDENTIFYING BIOLOGICAL PARTICLES IN A FLOW STREAM - A method for increasing the throughput, or the precision, or both the precision and the throughput, of a flow cytometer, or of a hematology analyzer employing a flow cytometer, by utilizing the technique of laser rastering. Laser rastering involves sweeping a laser beam across a flowing sample stream in a hematology analyzer. An apparatus suitable for carrying out the method of this invention comprises an optical module comprising a source of light, a scanning device, a lens or system of lenses, a flow cell, detectors, and filters; and an electronic module comprising preamplifiers, analog signal conditioning elements, analog-to-digital converters, field-programmable gate arrays, digital signal processing elements, and data storage elements. | 09-22-2011 |
| 20110275064 | METHOD FOR HEMATOLOGY ANALYSIS - A method whereby one or more fluorescent dyes are used to bind and stain nucleic acids in certain blood cells, such as, for example, white blood cells, nucleated red blood cells, and reticulocytes, and to induce fluorescent emissions upon excitation of photons from a given source of light, such as, for example, a laser, at an appropriate wavelength. More particularly, this invention provides a method whereby a fluorescent trigger is used in a data collection step for collecting events that emit strong fluorescence, in order to separate white blood cells and nucleated red blood cells from red blood cells and platelets without the need for using a lysing agent. | 11-10-2011 |
| Patent application number | Description | Published |
| 20100192937 | Jet Cavity Catalytic Heater - The present invention is a method of delivering vaporized alcohol fuel through a thermally conductive porous nozzle to a catalytic burner with a plasma cavity and a surrounding porous catalytic cavity with fuel vapor and air supplied separately and inter diffusing into each other from different routes to the catalyst to achieve an efficient, steady, and complete combustion of the hydrogen bearing fuels. This heating system with passive auto thermostatic behavior, coupled to thermopiles, heat pipes and fluid heating systems may provide useful heat and electricity to applications of floors, roadways, runways, electronics, refrigerators, machinery, automobiles, structures, and fuel cells. | 08-05-2010 |
| 20100236949 | Safety Fuel Transportation, Storage, and Delivery System - The present invention is an assembly for transporting, storing, and delivering a fuel such that a compromise to the containment of the fuel is readily recognized. | 09-23-2010 |
| 20110197873 | DEVICE FOR TRANSFERRING HEAT AND A RELATED MEANS OF TRIGGERING A CONTROLLED COMBUSTION - The present invention is a means of starting a controlled combustion reaction by introducing sodium borohydride or similar chemical to a liquid or gelatinous fuel. The present invention is also a device for transferring heat having a thermal conductor connected to a catalyst such that the thermal conductor is positioned within a liquid or gelatinous fuel held within a fuel container. | 08-18-2011 |