Patent application number | Description | Published |
20090246837 | Process for The Preparation of Optically Active Chiral Amines - The present invention relates to the production of optically pure secondary amines, which can be used as intermediate products in a synthesis of for instance pharmaceutical products. | 10-01-2009 |
20090311745 | GROUP OF ESTERASES FOR THE ENANTIOSELECTIVE PRODUCTION OF FINE AND SPECIALITY CHEMICALS - The present invention relates to a polynucleotide encoding an enzyme having carboxylesterase [E.C. 3.1.1.1] activity, wherein the coding sequence is selected from the group consisting of (a) a polynucleotide encoding an amino acid sequence as depicted in any one of SEQ ID NOs: 2, 4, 6, 8, 10 and 12; (b) a polynucleotide having or comprising a nucleotide sequence encoding an enzyme, wherein the nucleic acid sequence is as shown in any one of SEQ ID NOs: 1, 3, 5, 7, 9 and 11; (c) a polynucleotide having or comprising a nucleotide sequence encoding a fragment or derivative of an enzyme encoded by a polynucleotide of (a) or (b), wherein in said derivative one or more amino acid residues are conservatively substituted compared to the amino acid sequence of (a); (d) a polynucleotide encoding an enzyme having carboxylesterase activity which polynucleotide is at least 66% identical to a polynucleotide encoding an enzyme as shown in one of SEQ ID NOs: 2, 4, 6, 8, 10 and 12; (e) a polynucleotide having or comprising a nucleotide sequence the complementary strand of which hybridizes to a polynucleotide as defined in any one of (a) to (d); and (f) a polynucleotide having or comprising a nucleotide sequence being degenerate to the nucleotide sequence of the polynucleotide of (d) or (e); or the complementary strand of such a polynucleotide of (a) to (f) or fragments thereof useful as specific probes or primers. The present invention also relates to a host genetically engineered with the polynucleotide of the present invention or the vector of the present invention. The present invention also relates to a process for producing a polypeptide having carboxylesterase [E.C. 3.1.1.1] activity, comprising culturing the host of the present invention and recovering the polypeptide produced by said host. Moreover, The present invention also relates to a process for producing bacteria or eukaryotic cells capable of expressing a polypeptide having carboxylesterase [E.C. 3.1.1.1] activity, the process comprising genetically engineering bacteria or eukaryotic cells with the vector of the present invention. Finally, the present invention relates to (poly)peptides, antibodies, compositions and various methods for the production of optically active compounds. | 12-17-2009 |
20090325224 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE N-PROTECTED 3-AMINOPYRROLIDINE OR OPTICALLY ACTIVE N-PROTECTED 3-AMINOPIPERIDINE AND THE CORRESPONDING KETONES BY OPTICAL RESOLUTION OF THE RACEMIC AMINE MIXTURES EMPLOYING A BACTERIAL OMEGA-TRANSAMINASE - The present invention relates to the production of optically active amines, which can be used as intermediate products in a synthesis of for instance pharmaceutical products. | 12-31-2009 |
20100021964 | MICROORGANISM FOR PRODUCING RECOMBINANT PIG LIVER ESTERASE - The present invention relates to a microorganism which comprises at least one copy of a polynucleic acid sequence which is foreign to the host and which encodes a protein having an enzymic activity, and comprises a chaperone system which assists the expression of the protein in the form of an active enzyme, and to a method for producing a protein having esterase activity using such a microorganism. | 01-28-2010 |
20110207186 | Isoforms of Pig Liver Esterase - The invention relates to novel mutants of γPLE, to vehicles containing the same and to their use in the production of enantiomer-enriched alcohols, carboxylic acids and esters. | 08-25-2011 |
20120156706 | PROCESS FOR THE IDENTIFICATION AND PREPARATION OF A (R)-SPECIFIC OMEGA-TRANSAMINASE - The present invention relates to processes for the screening, preparation and characterization of (R)-selective ω-transaminases, to transaminases obtained thereby and their uses in various transamination processes. | 06-21-2012 |
20120276247 | Lipase Variants - The present invention relates to a newly identified lipase belonging to the Ustilaginaceae family of | 11-01-2012 |
20130171321 | REDUCED-FAT FOODSTUFFS AND COOKING OILS, AND METHODS FOR MAKING SAME - The present invention relates to a newly identified lipase belonging to the Ustilaginaceae family of Basidomycetes and variants thereof. The invention also relates to polynucleotides encoding the lipase and the variants thereof. The invention further relates to procedures for producing the lipase, and variants thereof, polypeptides and polynucleotides. The invention further relates to lipase variants with an increased trans-selectivity. The invention further relates to lipase variants with a preference for long chain fatty acid esters or carboxylic acid moieties with a chain length greater than C | 07-04-2013 |
20130196411 | POLYNUCLEOTIDES, VECTORS, AND HOST CELLS EXPRESSING IMPROVED LIPASE VARIANTS - The present invention relates to a newly identified lipase belonging to the Ustilaginaceae family of Basidomycetes and variants thereof. The invention also relates to polynucleotides encoding the lipase and the variants thereof. The invention further relates to procedures for producing the lipase, and variants thereof, polypeptides and polynucleotides. The invention further relates to lipase variants with an increased trans-selectivity. The invention further relates to lipase variants with a preference for long chain fatty acid esters or carboxylic acid moieties with a chain length greater than C | 08-01-2013 |