Patent application number | Description | Published |
20080200897 | MODULAR COMBINATION OF MEDICATION INFUSION AND ANALYTE MONITORING - Methods and systems for providing modular components in an integrated infusion device and analyte monitoring system where the components are independently replaceable are provided. | 08-21-2008 |
20090259118 | Shallow Implantable Analyte Sensor with Rapid Physiological Response - Methods and devices to detect analyte in body fluid are provided. Embodiments include analyte sensors designed so that at least a portion of the sensor is positionable beneath a skin surface in the dermal layer. | 10-15-2009 |
20090292188 | Analyte Sensors and Methods of Use - An analyte sensor system including a substrate, a first electrode disposed on a first surface of the substrate, a second electrode disposed on a second surface of the substrate, a third electrode provided in electrical contact with at least one of the first or second electrodes, where at least a portion of the first electrode and the second electrode are subcutaneously positioned in a patient, and where the third electrode is substantially entirely positioned external to the patient, and corresponding methods are provided. | 11-26-2009 |
20100030052 | ANALYTE SENSORS COMPRISING PLASTICIZERS - A method and analyte-measurement device adapted to determine the concentration of an analyte in a fluid from a measurement site within a body, including an animal body, a mammalian body, or a human body. The invention further relates to the use of partially or fully implantable glucose-monitoring devices, including transcutaneous or subcutaneous glucose-monitoring devices. Devices, systems and kits making use of the aforementioned method are provided as well. | 02-04-2010 |
20100081905 | ANALYTE SENSORS COMPRISING LEVELING AGENTS - Generally, embodiments of the invention relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of one or more components of the sensor by inclusion of a low surface tension polymer leveling agent, where the components are disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 04-01-2010 |
20100198034 | Compact On-Body Physiological Monitoring Devices and Methods Thereof - Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned analyte sensor automatically or on demand upon request from a user. | 08-05-2010 |
20100230285 | Analyte Sensors and Methods of Making and Using the Same - Methods and systems for providing continuous analyte monitoring including in vivo sensors that do not require any user calibration during in vivo use are provided. Also provided are methods and devices including continuous analyte monitoring systems that include in vivo sensors which do not require any system executed calibration or which do not require any factory based calibration, and which exhibit stable sensor sensitivity characteristics. Methods of manufacturing the no calibration sensors and post manufacturing packaging and storage techniques are also provided. | 09-16-2010 |
20100274112 | Modular Combination Of Medication Infusion And Analyte Monitoring - Methods and systems for providing modular components in an integrated infusion device and analyte monitoring system where the components are independently replaceable are provided. | 10-28-2010 |
20100274515 | Dynamic Analyte Sensor Calibration Based On Sensor Stability Profile - Dynamic sensor calibration schedule management including determining a stability profile of an in vivo analyte sensor in fluid contact with a biological fluid, processing the determined stability profile in conjunction with calibration criteria for the analyte sensor, and modifying a predetermined sensor calibration schedule based on the processed stability profile is provided. | 10-28-2010 |
20100324392 | ANALYTE SENSOR AND APPARATUS FOR INSERTION OF THE SENSOR - An apparatus for insertion of a medical device in the skin of a subject is provided. | 12-23-2010 |
20100326842 | Extruded Electrode Structures and Methods of Using Same - The present disclosure provides electrode structures and integrated electrode structures having one or more conductive materials coextruded with one or more dielectric materials. The disclosed electrode structures can be configured for use as analyte sensors. Also provided, are methods of making and using the electrode structures and integrated electrode structures described herein. | 12-30-2010 |
20100331643 | Extruded Analyte Sensors and Methods of Using Same - The present disclosure provides electrode structures and integrated electrode structures having one or more conductive materials coextruded with one or more dielectric materials. The disclosed electrode structures can be configured for use as analyte sensors. Also provided, are methods of making and using the electrode structures and integrated electrode structures described herein. | 12-30-2010 |
20100331646 | Health Management Devices and Methods - Methods and devices to detect analyte in body fluid are provided. Embodiments include analyte sensors designed so that at least a portion of the sensor is positionable beneath a skin surface during analyte monitoring. | 12-30-2010 |
20100331771 | INTEGRATED DEVICES HAVING EXTRUDED ELECTRODE STRUCTURES AND METHODS OF USING SAME - The present disclosure provides electrode structures and integrated electrode structures having one or more conductive materials coextruded with one or more dielectric materials. The disclosed electrode structures can be configured for use as analyte sensors. Also provided, are methods of making and using the electrode structures and integrated electrode structures described herein. | 12-30-2010 |
20110021889 | Continuous Analyte Measurement Systems and Systems and Methods for Implanting Them - Low profile continuous analyte measurement systems and systems and methods for implantation within the skin of a patient are provided. | 01-27-2011 |
20110046465 | Analyte Sensors and Methods of Use - An analyte sensor system including a substrate, a first electrode disposed on a first surface of the substrate, a second electrode disposed on a second surface of the substrate, a third electrode provided in electrical contact with at least one of the first or second electrodes, where at least a portion of the first electrode and the second electrode are subcutaneously positioned in a patient, and where the third electrode is substantially entirely positioned external to the patient, and corresponding methods are provided. | 02-24-2011 |
20110120865 | Analyte Sensors Comprising High-Boiling Point Solvents - Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a high-boiling point solvent, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 05-26-2011 |
20110124993 | Analyte Sensors Comprising Self-Polymerizing Hydrogels - Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a self-polymerizing hydrogel, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 05-26-2011 |
20110124994 | Analyte Sensors Comprising Hydrogel Membranes - Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved signal response and stability by inclusion of a coating including a hydrogel, a crosslinker, and a swelling modulator, where the coating is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 05-26-2011 |
20110160696 | INJECTION PORT DEVICE ADAPTED FOR USE WITH INSULIN PUMP - An injection port comprises a body having an outlet delivery cannula configured to pierce subcutaneous tissue of a patient to deliver medication. The port includes multiple injection sites, each of which can be used multiple times, and each of which is sealed. Each injection port is configured to temporarily receive a delivery device and reseal itself when the delivery device is removed. In one embodiment, a seal includes a pierceable stationary septum that reseals itself when a sharp cannula is removed. One injection site also includes locking features to receive a locking device of a delivery device and temporarily lock the delivery device in place at the injection site. The locking device may later be unlocked when delivery is complete and removed. In one application, a diabetic may use one injection site for syringes during the day and the locking injection site for a insulin pump during sleeping hours. | 06-30-2011 |
20110213225 | Medical devices and methods - Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user. | 09-01-2011 |
20110257495 | Analyte Monitoring Device and Methods - Method and system for determining real time analyte concentration including an analyte sensor having a portion in fluid contact with an interstitial fluid under a skin layer, an on-body electronics including a housing coupled to the analyte sensor and configured for positioning on the skin layer, the on-body electronics housing including a plurality of electrical contacts , on the housing; and a data analysis unit having a data analysis unit housing and a plurality of probes , on the housing. Each of the probes configured to electrically couple to a respective electrical contact when the data analysis unit is positioned in physical contact with the on-body electronics. The one or more signals on the probes correspond to one or more of a substantially real time monitored analyte concentration level (MACL), MACL over a predetermined time period, or a rate of change of the MACL, or combinations thereof, are provided. | 10-20-2011 |
20120028283 | Analyte Sensors Having Temperature Independent Membranes - Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane structure with an analyte permeability that is substantially temperature independent. The devices also include a sensing layer disposed on a working electrode of in vivo analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 02-02-2012 |
20120088995 | Analyte Monitoring Devices and Methods - Methods and devices for providing application specific integrated circuit architecture for a two electrode analyte sensor or a three electrode analyte sensor are provided. Systems and kits employing the same are also provided. | 04-12-2012 |
20120138484 | Analyte Sensors Comprising Thickeners, Enzyme Stabilizers and Osmium Boronates - Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution and/or improved sensitivity and/or reduced sensitivity variation of the sensing layer by inclusion of a thickener and/or an enzyme stabilizer in the sensing layer. Embodiments of the present disclosure also relate to transition metal complexes having at least one pyridine boronic acid ligand are also described. Aspects of the disclosure include transition metal complexes chemically bonded to a polymer, such as a sensing layer polymer. The sensing layer is disposed on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 06-07-2012 |
20120150005 | Analyte Sensors with a Sensing Surface Having Small Sensing Spots - Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes two or more sensing elements disposed laterally to each other, where the sensing surface is on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 06-14-2012 |
20120157801 | Adaptor for On-Body Analyte Monitoring System - An analyte monitoring system comprising: an on-body housing; an analyte sensor coupled to the housing; an electrical output interface disposed on an outer surface of the housing; and a removable adaptor coupled to the housing. In one embodiment, a portion of the analyte sensor extends from the housing for implantation into a patient's body. The electrical output interface is electrically coupled to the analyte sensor. The removable adaptor is mechanically coupled to the housing and electrically coupled to the electrical output interface. The removable adaptor serves as a data conduit between the analyte sensor and a remote device. | 06-21-2012 |
20120296186 | Analyte Sensors Having a Membrane with Low Temperature Sensitivity - Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane with low temperature sensitivity. The sensing layer is disposed on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 11-22-2012 |
20120296189 | Methods of Collecting and Analyzing Samples - Provided are methods of measuring analyte concentrations in interstitial fluid samples, methods of determining accuracy of subcutaneously implantable analyte sensors, methods of manufacturing and determining calibration factors for subcutaneously implantable analyte sensors, as well as subcutaneously implantable analyte sensors manufactured according to the described methods and having a high level of accuracy. Methods of determining the concentration of an analyte in a bodily sample, and methods of extracting interstitial fluid are also provided. | 11-22-2012 |
20120323098 | Connectors for Making Connections Between Analyte Sensors and Other Devices - Analyte sensor connectors that connect analyte sensors, e.g., conductive members of analyte sensors, to other devices such as sensor electronics units, e.g., sensor control units, are provided. Also provided are systems that include analyte sensors, analyte sensor connectors, and analyte sensor electronics units, as well as methods of establishing and maintaining connections between analyte sensors and analyte sensor electronics units, and methods of analyte monitoring/detection. Also provided are methods of making analyte sensor connectors and systems that include analyte sensor connectors. | 12-20-2012 |
20130004649 | Analyte Sensors Comprising Self-Polymerizing Hydrogels - Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a self-polymerizing hydrogel, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 01-03-2013 |
20130150691 | Analyte Sensor Devices, Connections, and Methods - Devices associated with on-body analyte sensor units are disclosed. These devices include any of packaging and/or loading systems, applicators and elements of the on-body sensor units themselves. Also, various approaches to connecting electrochemical analyte sensors to and/or within associated on-body analyte sensor units are disclosed. The connector approaches variously involve the use of unique sensor and ancillary element arrangements to facilitate assembly of separate electronics assemblies and sensor elements that are kept apart until the end user brings them together. | 06-13-2013 |
20130158376 | Temperature-Compensated Analyte Monitoring Devices, Systems, and Methods Thereof - Methods, devices and systems related providing accurate glucose levels in view of temperatures that may adversely affect glucose value. | 06-20-2013 |
20130189421 | Analyte Sensors Comprising High-Boiling Point Solvents - Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a high-boiling point solvent, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 07-25-2013 |
20130345534 | Electrodes with Conductive Polymer Underlayer - The disclosure provides method and materials for preparing biosensors (e.g., in vitro test strips and in vivo sensors) with improved mechanical properties. In some aspects, for example, the electrochemical sensors have improved durability and are better able to withstand mechanical and electrochemical stresses such as those encountered during manufacturing, transportation, storage, and use (e.g., in vivo positioning, in vivo operation, or in vitro operation). Also for example, in some aspects the electrochemical sensors are less susceptible to pinholes and other manufacturing defects that degrade performance in traditional sensors. | 12-26-2013 |
20140060145 | Analyte Monitoring Methods, Devices and Systems for Recommending Confirmation Tests - In some aspects, methods, devices, and systems for monitoring sensor data and indicating recommendations for confirmation tests on a user interface are provided. Sensor data is received and is monitored to detect predetermined signal characteristics that are associated with a likelihood of inaccuracy of the sensor data. A recommendation for a confirmation test to be performed is indicated on a user interface after the occurrence of a predetermined signal characteristic is detected. | 03-06-2014 |
20150065833 | Analyte Sensors Comprising High-Boiling Point Solvents - Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a high-boiling point solvent, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring. | 03-05-2015 |