Turtle
Allan Turtle, Abertillery GB
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20120156559 | METHOD OF ASSEMBLING A BIPOLAR BATTERY - A method of sealing together two elements of a bipolar battery, the method comprising: interposing an inductive heating element between the two elements; applying a current to the inductive heating element to generate localised heat to melt material in the vicinity of the heating element to seal the two elements together. | 06-21-2012 |
Cameron J Turtle, Seattle, WA US
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20110059012 | IDENTIFICATION OF CD8+ T CELLS THAT ARE CD161HI AND/OR IL18R (ALPHA) HI AND HAVE RAPID DRUG EFFLUX CAPACITY - This invention provides, among other things, methods for the identification and isolation of viable putative long-lived antigen-specific memory CD8 | 03-10-2011 |
Cameron John Turtle, Queensland AU
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20090098090 | VITRO IMMUNIZATION - The present invention relates generally to a method of generating lymphocytes specific for particular antigens. More particularly, the present invention provides a method for generating antigen-reactive T- cells and even more particularly cytotoxic (CD8+) T-cells in 10 vitro specific for antigens such as peptide antigens. The method of the present invention enables in vitro T-cell priming for particular antigens such as antigens on cancer cells, pathogenic cells, viruses or cells infected with viruses. The present invention is useful in identifying particularly immunogenic antigens for immunotherapy. Furthermore, as a consequence, the present invention is useful in avoiding the need for expensive and time 15 consuming clinical trials. The present invention further provides a method for the treatment or prophylaxis of a disease or condition in a subject by generating T-cells reactive to an antigenic molecule and administering an effective amount of antigen-reactive T-cells to the subject or other compatible host. Furthermore, the present invention permits the generation of dendritic cell/T-cell populations for use in cellular immunotherapy. | 04-16-2009 |
Eric Turtle, San Francisco, CA US
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20100331400 | CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS - The present invention relates to novel compounds of formula (I), methods, and compositions capable of decreasing HIF hydroxylase activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF). | 12-30-2010 |
Eric D. Turtle, Belmont, CA US
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20080293763 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF - The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. | 11-27-2008 |
20100303928 | ISOXAZOLOPYRIDINE DERIVATIVES FOR USE IN THE TREATMENT OF HIF-MEDIATED CONDITIONS - The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF) by inhibiting the activity of at least one HIF hydroxylase enzyme. | 12-02-2010 |
20110212959 | Cyanoisoquinoline Compounds and Methods of Use Thereof - The present invention relates to cyanoisoquinoline compounds suitable for use in treating hypoxia inducible factor-mediated and/or erythropoietin-associated conditions. The cyanoisoquinoline compounds of the invention have the following structure: | 09-01-2011 |
20110305776 | THIOCHROMENE DERIVATIVES AS HIF HYDROXYLASE INHIBITORS - The present invention relates to novel compounds, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF). | 12-15-2011 |
20120029011 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF - The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. | 02-02-2012 |
20120178755 | CYANOISOQUINOLINE COMPOUNDS AND METHODS OF USE THEREOF - The present invention relates to cyanoisoquinoline compounds suitable for use in treating hypoxia inducible factor-mediated and/or erythropoietin-associated conditions. The cyanoisoquinoline compounds of the invention have the following structure: | 07-12-2012 |
20130178417 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF - The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. | 07-11-2013 |
20130310565 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF - The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. | 11-21-2013 |
20140221422 | NOVEL THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF - The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF). | 08-07-2014 |
20140343094 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF - The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. | 11-20-2014 |
20150031696 | CYANOISOQUINOLINE COMPOUNDS AND METHODS OF USE THEREOF - The present invention relates to cyanoisoquinoline compounds suitable for use in treating hypoxia inducible factor-mediated and/or erythropoietin-associated conditions. The cyanoisoquinoline compounds of the invention have the following structure: | 01-29-2015 |
Eric Douglas Turtle, Belmont, CA US
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20120129793 | Antimicrobial Polyether and Polyol Compounds - The present application describes compounds of Formula I and Formula IA and as disclosed herein, that are useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents. | 05-24-2012 |
20120211027 | Contact Lens Cleaning System with Monitor - The invention monitors the neutralization process involving hydrogen peroxide solution and a hydrogen peroxide neutralization catalyst and compares measured values with theoretical values. The system monitors the chemical reaction and notifies the user of the neutralization status. In an exemplary embodiment, the initial hydrogen peroxide solution concentration is neutralized with a palladium catalyst after a period of time. A microcontroller analyzes the measurements and displays the neutralization process results using colored LED lights and/or text or images on a LCD display. In one embodiment, an apparatus adapted for use with a cleaning solution used to clean a medical device may include a trigger, a processing device in communication with the trigger, and a display device. The processing device provides a trigger count and the display device communicates with the processing device and displays a message based on the count. | 08-23-2012 |
20140094495 | Antimicrobial Haloalkyl Heterocycle Compounds - This application describes compounds useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents. | 04-03-2014 |
Howard Turtle, Jackson, WY US
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20100005388 | SYSTEM AND METHOD FOR PROCESSING FORMATTED TEXT DOCUMENTS IN A DATABASE - A system and method for automatically determining a plurality of pieces of different information about a textual document from the text of the textual document are provided in which one or more particular characteristics of the text of the textual document are identified to generate a file containing the text of the textual document with the particular characteristics marked up within the text. In addition, any negative treatment of other textual documents from the text of the textual document is determined to generate negative treatment information, a data record is produced indicating a depth of treatment for each other textual documents cited in the text of the textual document, the source of a quotation in the text of the textual document is verified to generate verified quotation information, any subject matter text that is applicable to the text of the textual document is determined to generate subject matter headings associated with the text of the textual document, and a data record is generated containing the identified characteristics of the textual document, the negative treatment of other textual documents cited in the textual document, the depth of treatment of other textual documents cited in the textual document, the verified quotation information, and the subject matter text associated with the textual document so that all of the information is accessible. | 01-07-2010 |
20140180935 | SYSTEM AND METHOD FOR PROCESSING FORMATTED TEXT DOCUMENTS IN A DATABASE - A system and method for automatically determining a plurality of pieces of different information about a textual document from the text of the textual document are provided in which one or more particular characteristics of the text of the textual document are identified to generate a file containing the text of the textual document with the particular characteristics marked up within the text. | 06-26-2014 |