Patent application number | Description | Published |
20130337017 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE - Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented. | 12-19-2013 |
20140377215 | DELIVERY OF THERAPEUTIC AGENTS BY A COLLAGEN BINDING PROTEIN - Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. In these methods, the therapeutic agent is not a PTH/PTHrP receptor agonist or antagonist, basic fibroblast growth factor (bFGF) or epidermal growth factor (EGF). The bacterial collagen-binding polypeptide segment delivers the agent to sites of partially untwisted or under-twisted collagen. Methods of treating collagenopathies using a composition including a collagen-binding polypeptide and a PTH/PTHrP receptor agonist are also provided. In addition, methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. Finally, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided. | 12-25-2014 |
20150038423 | DELIVERY OF THERAPEUTIC AGENTS BY A COLLAGEN BINDING PROTEIN - Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided. | 02-05-2015 |
Patent application number | Description | Published |
20120282797 | ELECTRICALLY CONDUCTING TERMINAL - An electrically conducting terminal having capabilities to facilitate electrically connecting to one or more connectors is disclosed. The electrically conducting terminal may include a recessed end to receive a connector. The recessed end may include a resilient element, such as but not limited to a female contact, to facilitate electrical conductivity between the connector and the terminal. The electrically conducting terminal may include an end cap, end piece, or other feature to facilitate retaining the resilient element within the recessed end. | 11-08-2012 |
20120282823 | FEMALE TYPE CONTACT FOR AN ELECTRICAL CONNECTOR - A female type contact is provided for use with an electrical connector. The female type contact includes a body portion and a plurality of flexible beams that extend from the body portion. The flexible beams include a base portion having a first width and a tip portion having a second width that is smaller than the first width of the base portion. | 11-08-2012 |
20130017739 | FEMALE TYPE CONTACT FOR AN ELECTRICAL CONNECTORAANM Glick; MichaelAACI Farmington HillsAAST MIAACO USAAGP Glick; Michael Farmington Hills MI USAANM Pavlovic; SlobodanAACI NoviAAST MIAACO USAAGP Pavlovic; Slobodan Novi MI USAANM Mott; Allen LeoAACI LivoniaAAST MIAACO USAAGP Mott; Allen Leo Livonia MI USAANM Sadras-Ravindra; TulasiAACI CantonAAST MIAACO USAAGP Sadras-Ravindra; Tulasi Canton MI US - A female contact is provided for an electrical connector. The female contact includes a body portion and a plurality of flexible beams that extend from the body portion. The body portion is biased for engagement with a connector housing. The flexible beams taper from a first width this is near the body portion to a second width that is smaller than the first width. | 01-17-2013 |
20130109221 | ELECTRICAL TERMINAL AND RECEPTACLE ASSEMBLY | 05-02-2013 |
20140087601 | ELECTRICAL TERMINAL - An electrical terminal includes a contact portion having a contact portion base with at least three sides forming a generally polyhedron structure. The contact portion has a plurality of contact arms, with at least one of the contact arms extending from at least some of the sides. The contact arms are arranged to receive a mating electrical component such that the mating electrical component contacts at least one of the contact arms associated with each side. A spring arrangement includes a plurality of spring arms, each having a spring head in contact with at least one respective contact arm near a distal end of the contact portion for applying a force thereto in a direction toward a central axis of the terminal, thereby increasing the retention force applied to the mating electrical component. | 03-27-2014 |
20140087602 | ELECTRICAL TERMINAL - An electrical terminal includes a contact portion having a contact portion base with at least three sides forming a generally polyhedron structure. At least one contact arm extends from at least some of the sides, and are arranged to receive a mating electrical component. A spring arrangement includes a plurality of spring arms extending from a spring base. Each of the spring arms includes a spring head in contact with at least one respective contact arm near a distal end of the contact portion for applying a force thereto in a direction toward a central axis of the terminal. The spring base includes a support structure configured to support the mating electrical component. | 03-27-2014 |
20140206243 | ELECTRICALLY CONDUCTING TERMINAL - An electrically conducting terminal having capabilities to facilitate electrically connecting to one or more connectors is disclosed. The electrically conducting terminal may include a recessed end to receive a connector. The recessed end may include a resilient element, such as but not limited to a female contact, to facilitate electrical conductivity between the connector and the terminal. The electrically conducting terminal may include an end cap, end piece, or other feature to facilitate retaining the resilient element within the recessed end. | 07-24-2014 |
20140235113 | FEMALE ELECTRICAL CONNECTOR WITH TERMINAL ARM EXTENSION PROTECTION - A female electric connector includes a terminal body with a plurality of terminal arms. The terminal arms extend from the terminal body around a terminal axis. The female electric connector includes an over-deflection protection that limits deflection of the terminal arms in an inward direction generally toward the terminal axis. | 08-21-2014 |
20140235114 | Cylindrical Electric Connector with Biased Contact - An electric connector includes a terminal body defining an interior space. An electric contact is located within the internal space. The electric contact includes a base contact ring that is biased into engagement with the terminal body and an outer ring that is biased into engagement with the terminal body. A contact arm extends from the base contact ring to the outer ring. | 08-21-2014 |
20140273659 | Terminal With Front End Protection - An electric terminal includes a conductive portion with a base and a plurality of contact arms extending therefrom. The electric terminal includes a protective shroud that extends farther from the base than the contact arms do. | 09-18-2014 |
20150038000 | ELECTRICAL TERMINAL ASSEMBLY - An electrical assembly includes a base having a body including a first end and a second end. First and second opposed base beams extend from the first end of the body in a first direction. The assembly further includes a spring clamp having a clamp base and first and second opposed spring beams extending from the clamp base in the first direction and disposed over the first and second base beams biasing the first and second base beams towards one another. The spring clamp is assembled onto the base by moving the spring clamp along the first direction onto the base. A locking feature is integrally formed in the base and the spring clamp preventing the removal of the spring clamp from the base along a second direction opposite the first direction. The locking feature also prevents movement of the spring clamp relative to the base in a lateral direction normal to the first direction. | 02-05-2015 |
20150038024 | Electrical Terminal Assembly - An electrical terminal assembly includes a base having a body including a first end and a second end. First and second opposed base beams extend from the first end of the body in a first direction. A spring clamp has a clamp base and first and second opposed spring beams extending from the clamp base in the first direction and disposed over the first and second base beams biasing the first and second base beams toward one another. The body of the base is configured to permit the spring clamp to be inserted onto the base in a second direction normal the first direction. | 02-05-2015 |
20150074996 | Method of Assembling An Electrical Terminal Assembly - A method of assembling an electrical terminal having a base and a spring member. The base is provided with a plurality of base beams. The spring member is provided with a plurality of spring beams. The spring member defines an axis such that the plurality of spring beams is spaced radially apart from the axis. The spring beams deflected radially outwardly. The base is inserted in the spring member to position the base beams adjacent to the spring beams. The spring beams are released such that the spring beams retract radially inwardly against the base beams. | 03-19-2015 |
20150079859 | Electrical Terminal Assembly - An electrical terminal assembly has a base and a spring member. The base defines an axis and including a plurality of base beams deflectable in a radial direction relative to the axis. The spring member has a main portion disposed over the base. The spring member includes a plurality of spring beams extending from a front end of the main portion. The spring beams bias the base beams radially inwardly towards the axis. The main portion is made from a folded blank having a first edge that is permanently secured to a second edge such that the edges cannot be pulled apart from one another. | 03-19-2015 |