Tuan
Ashley Tuan, Mountain View, CA US
Patent application number | Description | Published |
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20140069438 | CONFORMABLE THERAPEUTIC SHIELD FOR VISION AND PAIN - A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10-4 Pa*m3 to about 5×10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected. | 03-13-2014 |
20140251347 | CONFORMABLE THERAPEUTIC SHIELD FOR VISION AND PAIN - A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected. | 09-11-2014 |
Ashley Tuan, Menlo Park, CA US
Patent application number | Description | Published |
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20120310133 | Conformable Therapeutic Shield for Vision and Pain - A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10-4 Pa*m3 to about 5×10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected. | 12-06-2012 |
20130025606 | Conformable Therapeutic Shield for Vision and Pain - A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected. | 01-31-2013 |
20130070200 | Conformable Therapeutic Shield for Vision and Pain - A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected. | 03-21-2013 |
20140028979 | METHODS AND APPARATUS TO IDENTIFY EYE COVERINGS FOR VISION - Methods and apparatus can fit coverings to treat eyes. The covering can be identified so as to provide improved flow of tear liquid under the covering. The covering can be identified based on an inner corneal curvature and an outer corneal curvature and one or more of a limbus sag height or a conjunctival sag height. The covering may form a chamber when placed on the eye to pump tear liquid under at least a portion of the covering. The covering may comprise an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The covering may comprise a material having high oxygen permeability, for example silicone, with a wettable coating disposed on at least an upper surface of the coating. | 01-30-2014 |
20160067109 | CONFORMABLE THERAPEUTIC SHIELD FOR VISION AND PAIN - A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10-4 Pa*m3 to about 5×10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected. | 03-10-2016 |
Chao-Yang Tuan, Shenzhen City CN
Patent application number | Description | Published |
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20120206360 | Mouse Pen and Photoelectric Control Switch Thereof - A mouse pen and a photoelectric control switch thereof are provided, the photoelectric control switch includes a control rod in a shell moving between on-position and off-position, an optical coupling sensor comprising a light emitter and light receiver disposed on an extension line of the control rod, and an elastic element for resetting the control rod. The control rod includes a first end near the optical coupling sensor and equipped with a reflection element, and a second end for driving the control rod towards the optical coupling sensor which protrudes an orifice of the shell; at the on-position, light emitting from the light emitter is received by the light receiver after being reflected by the reflection element, while at the off-position, light cannot be received. The photoelectric control switch implements non-contact on/off controlling with the optical coupling sensor and the control rod, responses sensitively, and has longer lifetime. | 08-16-2012 |
Charles T. Tuan, Bountiful, UT US
Patent application number | Description | Published |
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20140261211 | FISH FOOD DISPENSER - An illuminating system for illuminating a vivarium from the side panel of a vivarium using light emitting diodes. A containment ring for dispensing fish food within an aquarium. A perforated container with a lid for dispensing food within a vivarium. A brush for cleaning a vivarium. A method for soaking food in a sinking tray. A method of dispensing bait from a perforated container. | 09-18-2014 |
20140261214 | FISH FOOD DISPENSER - A fish food dispensing assembly includes (i) a handle member; and (ii) a perforated container that is selectively, magnetically linked to the handle member with an aquarium panel therebetween. The perforated container is configured to receive fish food therein and to dispense fish food therefrom in a liquid environment. The fish food dispensing assembly also acts as a cleaner and can be moved with respect to the aquarium in order to clean the aquarium and/or position the fish food dispensing assembly in desired locations for feeding fish within the aquarium. | 09-18-2014 |
20140261215 | FISH FOOD DISPENSER - A fish food dispensing assembly is comprised of: (A) a handle member; (B) a perforated container that is selectively magnetically linked to a handle member; and (C) a fish food containment ring configured to be magnetically linked to the perforated container and to the handle member. The perforated container is configured to receive fish food therein and is placed within the containment ring such that the fish food dispensed within the aquarium is substantially dispensed within a specific location within the aquarium. A floating containment ring orients a brush plate in convenient parallel position for convenient linking to the handle member. LEDs on the handle member provide illumination in different colors. | 09-18-2014 |
Doan Minh Tuan, Burnsville, MN US
Patent application number | Description | Published |
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20140188062 | COLLECTION CATHETER AND KIT - A catheter for collecting fluid such as blood from a vessel such as a coronary sinus of a patient has an elongated, flexible tubular portion and an annular sealing member spaced from a distal end of the tubular member. A proximal end of the tubular member is adapted to be connected to a source of suction for applying suction to a collection lumen of the tubular member. The distal end is placed in a blood vessel with the sealing member spaced from opposing surface of the vessel in an absence of a suction applied to the collection lumen. Suction is applied to the collection lumen in an amount sufficient to draw blood from the vessel through the fluid inlet and into the collection lumen and further sufficient to urge the opposing surface of the vessel to migrate into sealing engagement with the sealing member. | 07-03-2014 |
Hsi-Ching Tuan, Shenzhen City CN
Patent application number | Description | Published |
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20120206360 | Mouse Pen and Photoelectric Control Switch Thereof - A mouse pen and a photoelectric control switch thereof are provided, the photoelectric control switch includes a control rod in a shell moving between on-position and off-position, an optical coupling sensor comprising a light emitter and light receiver disposed on an extension line of the control rod, and an elastic element for resetting the control rod. The control rod includes a first end near the optical coupling sensor and equipped with a reflection element, and a second end for driving the control rod towards the optical coupling sensor which protrudes an orifice of the shell; at the on-position, light emitting from the light emitter is received by the light receiver after being reflected by the reflection element, while at the off-position, light cannot be received. The photoelectric control switch implements non-contact on/off controlling with the optical coupling sensor and the control rod, responses sensitively, and has longer lifetime. | 08-16-2012 |
Hsing-Yu Tuan, Hsinchu US
Patent application number | Description | Published |
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20130202898 | METHOD FOR FABRICATING SEMICONDUCTOR NANOWIRE AND SEMICONDUCTOR NANOSTRUCTURE - A method for fabricating semiconductor nanowire includes the following steps: providing a metal substrate in a reactor; filling the reactor with an inert gas; heating and maintaining the reactor in a reaction temperature, raising the pressure in the reactor to a first predetermined pressure, and then passing a reacting precursor into the reactor; keeping passing the reacting precursor to raising the pressure of the reactor to a second predetermined pressure; and, maintaining the second predetermined pressure for a predetermined duration, so as to form semiconductor nanowires on the metal bulk. Accordingly, the method of the invention is capable of forming semiconductor nanowires on metal substrate, so that the processes for fabricating semiconductor nanowires can be simplified. | 08-08-2013 |
Jeh-Fu Tuan, San Jose, CA US
Patent application number | Description | Published |
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20130226535 | CONCURRENT SIMULATION SYSTEM USING GRAPHIC PROCESSING UNITS (GPU) AND METHOD THEREOF - A concurrent circuit simulation system simulate analog and mixed mode circuit using by exploiting parallel execution in one or more graphic processing units. In one implementation, the concurrent circuit simulation system includes a general purpose central processing unit (CPU), a main memory, simulation software and one or more graphic processing units (GPUs). Each GPU may contain hundreds of processor cores and several GPUs can be used together to provide thousands of processor cores. Software running on the CPU partitions the computation tasks into tens of thousands of smaller units and invoke the process threads in the GPU to carry out the computation tasks. | 08-29-2013 |
20140380259 | LAYOUT MIGRATION WITH HIERARCHICAL SCALE AND BIAS METHOD - A method for migrating a hierarchical layout between manufacturing processes is accomplished without specification of a technology file and design rules. Different scaling factors and bias values in the X and Y directions may be applied to each layer in the source hierarchical layout during the migration. In addition, the target hierarchical layout maintains connectivity, and is free of notches, jogs and small edges. A cell hierarchy tree is created, which guides expansion of the target hierarchical database to resolve issues related to rounding of floating point numbers to integers. Boolean operations are performed to determine the differences between target flat database and the target hierarchical database. The differences are eliminated by modifying the target hierarchical database to match the layout in the flat database. | 12-25-2014 |
20150269297 | METHODS FOR REDUCING POST LAYOUT CIRCUIT SIMULATION RESULTS - A method for reducing the size of post-layout circuit simulation output waveform database without a loss of essential information and accuracy. The reduced waveform database requires significantly less storage than the typical waveform database for post-layout simulation, thereby improving the time required for a waveform tool to access, and for a user to navigate, the post-layout simulation results. The method therefore greatly improves designer productivity during circuit verification and debugging phases. The method can be carried out in a preprocessor to a circuit simulator, in a post-processor to a circuit simulator, or may be directly built into a circuit simulator. The method is applicable to any post-layout netlists with schematic node names or circuit element names. | 09-24-2015 |
Kuangmon Ashley Tuan, Mountain View, CA US
Patent application number | Description | Published |
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20130077044 | Eye Covering and Refractive Correction Methods and Apparatus Having Improved Tear Flow, Comfort, and/or Applicability - An eye covering such as a contact lens may comprise one or more structures to pump tear liquid under the covering such that the covering can remain in the eye and correct vision for an extended amount of time. In many embodiments, the covering comprises a material having fenestrations to draw tear liquid under the covering and an outer portion shaped to contact the conjunctiva over the sclera, such that when the eye closes pressure of one or more eyelids urges tear liquid through one or more fenestrations and under the outer portion shaped to contact the conjunctiva. When the eye blinks, the pressure of the one or more eyelids can urge the covering toward the cornea such that tear liquid can pass through the fenestrations. | 03-28-2013 |
20130278890 | CONTACT LENSES FOR DIFFRACTIVE CORRECTION - Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include a deformable inner portion and a deformable peripheral portion. When disposed over the optical region of an eye, the inner portion is configured so that engagement of the posterior surface against the eye deforms the posterior surface so that the posterior surface has a shape diverging form the refractive shape of the epithelium when viewing with the eye through the ophthalmic lens. The rigidity of the inner portion is greater than the rigidity of the peripheral portion and the ophthalmic lenses are configured to allow movement relative to the eye upon blinking of the eye and to be substantially centered on the optical region of the cornea following the blinking of the eye. Methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses are also disclosed. | 10-24-2013 |
20130293832 | CONTACT LENSES FOR REFRACTIVE CORRECTION - Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include a deformable inner portion and a deformable peripheral portion. When disposed over the optical region of an eye, the inner portion is configured so that engagement of the posterior surface against the eye deforms the posterior surface so that the posterior surface has a shape diverging form the refractive shape of the epithelium when viewing with the eye through the ophthalmic lens. The rigidity of the inner portion is greater than the rigidity of the peripheral portion and the ophthalmic lenses are configured to allow movement relative to the eye upon blinking of the eye and to be substantially centered on the optical region of the cornea following the blinking of the eye. Methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses are also disclosed. | 11-07-2013 |
20140069439 | EYE COVERING AND REFRACTIVE CORRECTION METHODS FOR LASIK AND OTHER APPLICATIONS - A method for providing faster visual and functional recovery of patients following refractive surgery such as laser assisted in situ keratomileusis (LASIK) is disclosed. The method comprises providing a covering to the eye of a patient comprising an inner portion having an inner rigidity and at least one inner radius of curvature; and an outer portion having an outer rigidity and at least one outer radius of curvature; wherein the inner rigidity is greater than the outer rigidity. | 03-13-2014 |
20140362338 | EYE COVERING AND REFRACTIVE CORRECTION METHODS AND APPARATUS HAVING IMPROVED TEAR FLOW, COMFORT, AND/OR APPLICABILITY - An eye covering such as a contact lens may comprise one or more structures to pump tear liquid under the covering such that the covering can remain in the eye and correct vision for an extended amount of time. In many embodiments, the covering comprises a material having fenestrations to draw tear liquid under the covering and an outer portion shaped to contact the conjunctiva over the sclera, such that when the eye closes pressure of one or more eyelids urges tear liquid through one or more fenestrations and under the outer portion shaped to contact the conjunctiva. When the eye blinks, the pressure of the one or more eyelids can urge the covering toward the cornea such that tear liquid can pass through the fenestrations. | 12-11-2014 |
20150055081 | BIMODULAR CONTACT LENSES - Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include an inner optic portion configured to be disposed over the optical region of the cornea and having a central portion disposed between an anterior portion and a posterior portion. The inner optic portion is configured to at least partially diverge from the shape of the cornea to provide at least one lenticular volume between a posterior surface of the inner optic portion and the cornea. The central portion may be characterized by a thickness from 50 μm to 900 μm and a modulus form 20 MPa to 1500 MPa. | 02-26-2015 |
20150077701 | CONTACT LENSES FOR REFRACTIVE CORRECTION - Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include a deformable inner portion and a deformable peripheral portion. When disposed over the optical region of an eye, the inner portion is configured so that engagement of the posterior surface against the eye deforms the posterior surface so that the posterior surface has a shape diverging form the refractive shape of the epithelium when viewing with the eye through the ophthalmic lens. The rigidity of the inner portion is greater than the rigidity of the peripheral portion and the ophthalmic lenses are configured to allow movement relative to the eye upon blinking of the eye and to be substantially centered on the optical region of the cornea following the blinking of the eye. Methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses are also disclosed. | 03-19-2015 |
20150138500 | CONTACT LENSES HAVING A REINFORCING SCAFFOLD - Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include an inner optic portion having a scaffold between an anterior portion and a posterior portion. The scaffold is characterized by a substantially uniform thickness formed from a material characterized by a modulus that his higher than the modulus of the peripheral portion. Openings within the scaffold are filled with a low modulus material. When applied to an eye, the lenses are configured to provide one or more lenticular volumes between the posterior surface of the lens and the cornea. The disclosure further relates to methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses. | 05-21-2015 |
Kuang-Mon Ashley Tuan, Pleasanton, CA US
Patent application number | Description | Published |
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20120176582 | Ophthalmic Lenses And Reduction of Accommodative Error - Ophthalmic lenses provide clear visual acuity and present a myopic defocused image to the lens wearer at both near and distant viewing distances. The present lenses are used in methods to reduce ocular accommodative error in lens wearers. Methods of manufacturing the present lenses are described. | 07-12-2012 |
Kuang-Mon Ashley Tuan, Castro Valley, CA US
Patent application number | Description | Published |
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20090168019 | Non-Invasive Measurement of Tear Volume Systems and Methods - Devices systems, and methods can measure, diagnose and/or characterize an eye of a patient, including physiologic and optical properties, such as hydration and tear volume in relation to an optical surface of the eye, including topography of a corneal surface of the eye and/or a wavefront elevation map of the eye. The system forms an image of a tear meniscus along an eyelid. The eye can be illuminated so that the meniscus appears as a dark band in the image. Tear volume can be determined by measuring a height across the tear meniscus. The tear volume can be used to determine the optical properties of the tear of the eye and to diagnose conditions of the eye. The patient can be screened for treatment of the eye with refractive surgery using a measured pupil size, hydration and topography and/or wavefront. | 07-02-2009 |
Kuang-Mon Ashley Tuan, Mountain View, CA US
Patent application number | Description | Published |
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20090247999 | CORNEAL IMPLANT SYSTEM, INTERFACE, AND METHOD - System, graphical user interface, and method for performing ophthalmic surgery on a cornea. The system includes a display presenting a plurality of images representing corneal implants, a laser assembly outputting a pulsed laser beam, and a control unit coupled to the laser assembly and display. The control unit directs the laser assembly to produce a cavity in the cornea via the pulsed laser beam in response to a selected image, and the cavity receives a corneal implant corresponding to the selected image. | 10-01-2009 |
20130201443 | Multifocal Contact Lenses And Related Methods And Uses To Improve Vision Of Presbyopic Subjects - Multifocal contact lenses and methods and uses are described. The multifocal contact lenses include an optic zone. The optic zone has an aspheric power profile that provides a near vision refractive power and a distance vision refractive power, and provides an Add power that corresponds to the difference between the near vision refractive power and the distance vision refractive power. The multifocal contact lenses can improve binocular vision of presbyopic subjects by being prescribed such that the non-dominant eye contact lens is over-corrected for distance vision, and both multifocal contact lenses are under-corrected for the Add power requirement of the subject. Batches and sets of multifocal contact lenses are also described. | 08-08-2013 |
Kunagmon Ashley Tuan, Mountain View, CA US
Patent application number | Description | Published |
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20140155800 | EYE COVERINGS FOR CORNEAL HEALING AND METHODS OF USE - Methods for providing faster visual and functional recovery of patients following ocular therapy such as ocular therapy involving manipulation of the ocular tissue and/or associated with a lesion external to the optical region and ocular therapy involving incising the ocular tissue and implanting a device within the optical region are disclosed. Methods of healing a trauma wound to a cornea and methods of protecting an eye of a patient from potential injury are also disclosed. The disclosed methods comprise providing a covering to the eye of a patient wherein the covering comprises an inner portion having an inner rigidity and at least one inner radius of curvature; and an outer portion having an outer rigidity and at least one outer radius of curvature; wherein the inner rigidity is greater than the outer rigidity. | 06-05-2014 |
Ling Liu Tuan, Bountiful, UT US
Patent application number | Description | Published |
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20140261211 | FISH FOOD DISPENSER - An illuminating system for illuminating a vivarium from the side panel of a vivarium using light emitting diodes. A containment ring for dispensing fish food within an aquarium. A perforated container with a lid for dispensing food within a vivarium. A brush for cleaning a vivarium. A method for soaking food in a sinking tray. A method of dispensing bait from a perforated container. | 09-18-2014 |
20140261214 | FISH FOOD DISPENSER - A fish food dispensing assembly includes (i) a handle member; and (ii) a perforated container that is selectively, magnetically linked to the handle member with an aquarium panel therebetween. The perforated container is configured to receive fish food therein and to dispense fish food therefrom in a liquid environment. The fish food dispensing assembly also acts as a cleaner and can be moved with respect to the aquarium in order to clean the aquarium and/or position the fish food dispensing assembly in desired locations for feeding fish within the aquarium. | 09-18-2014 |
20140261215 | FISH FOOD DISPENSER - A fish food dispensing assembly is comprised of: (A) a handle member; (B) a perforated container that is selectively magnetically linked to a handle member; and (C) a fish food containment ring configured to be magnetically linked to the perforated container and to the handle member. The perforated container is configured to receive fish food therein and is placed within the containment ring such that the fish food dispensed within the aquarium is substantially dispensed within a specific location within the aquarium. A floating containment ring orients a brush plate in convenient parallel position for convenient linking to the handle member. LEDs on the handle member provide illumination in different colors. | 09-18-2014 |
Phac Le Tuan, San Jose, CA US
Patent application number | Description | Published |
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20110185008 | Methods and Apparatus for Supporting and Implementing Multi-User Interactions Including Shared Display Devices - Methods and apparatus for implementing multi-user casual interactions between users, a plurality of shared display devices, and/or a plurality of third-party devices. The methods include the ability for any user, without any registration prerequisite, to enter content on a handset and to cause certain content changes to be displayed on certain shared display devices, as well as related content information to be sent back to the requesting user's handset and optionally to other users' handsets or to certain third-party devices. The methods also include the ability for an operator to use a graphical user interface to create and manage the rules that control such behavior depending, among other parameters, on the user's submissions or on other users' submissions over a period of time. The methods enable the rules to be extended in an unlimited fashion thanks to the ability to interconnect with a plurality of third-party services. | 07-28-2011 |
Rocky S. Tuan, Pittsburgh, PA US
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20100179659 | CELL-NANOFIBER COMPOSITE AND CELL-NANOFIBER-HYDROGEL COMPOSITE AMALGAM BASED ENGINEERED INTERVERTEBRAL DISC - The instant invention is directed to a tissue engineered intervertebral disc comprising at least one inner layer and an exterior layer, wherein: the exterior layer comprises a nanofibrous polymer support comprising one or more polymer nanofibers; the at least one inner layer comprises a hydrogel composition comprising at least one or more hydrogel materials and/or one or more polymer nanofibers; and a plurality of cells which are dispersed throughout the tissue engineered intervertebral disc. Additionally, the instant invention is directed to methods of making such intervertebral discs and methods of treating intervertebral disc damage. | 07-15-2010 |
20120225039 | TISSUE ENGINEERED CARTILAGE, METHOD OF MAKING SAME, THERAPEUTIC AND COSMETIC SURGICAL APPLICATIONS USING SAME - Cartilage has been constructed using biodegradable electrospun polymeric scaffolds seeded with chondrocytes or adult mesenchymal stem cells. More particularly engineered cartilage has been prepared where the cartilage has a biodegradable and biocompatible nanofibrous polymer support prepared by electrospinning and a plurality of chondocytes or mesenchymal stem cells dispersed in the pores of the support. The tissue engineered cartilages of the invention possess compressive strength properties similar to natural cartilage. Methods of preparing engineered tissues, including tissue engineered cartilages, are provided in which an electrospun nanofibrous polymer support is provided, the support is treated with a cell solution and the polymer-cell mixture cultured in a rotating bioreactor to generate the cartilage. The invention provides for the use of the tissue engineered cartilages in the treatment of cartilage degenerative diseases, reconstructive surgery, and cosmetic surgery. | 09-06-2012 |
20160106548 | CELL-NANOFIBER COMPOSITE AND CELL-NANOFIBER-HYDROGEL COMPOSITE AMALGAM BASED ENGINEERED INTERVERTEBRAL DISC - The instant invention is directed to a tissue engineered intervertebral disc comprising at least one inner layer and an exterior layer, wherein: the exterior layer comprises a nanofibrous polymer support comprising one or more polymer nanofibers; the at least one inner layer comprises a hydrogel composition comprising at least one or more hydrogel materials and/or one or more polymer nanofibers; and a plurality of cells which are dispersed throughout the tissue engineered intervertebral disc. Additionally, the instant invention is directed to methods of making such intervertebral discs and methods of treating intervertebral disc damage. | 04-21-2016 |
Rocky S. Tuan, Bethesda, MD US
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20080274545 | Bioreactor Chamber Apparatus, and Method and System for Fabricating and Mechanically Stimulating Natural and Engineered Tissues - A bioreactor chamber assembly including a bioreactor chamber and an outer chamber assembly is provided. In one design, the bioreactor chamber includes an upper grip assembly having a plurality of struts extending downward terminating in upper grips, each strut terminating in an upper grip, and a lower grip assembly containing one or more sample compartments and a lower grip. A sample can be formed in situ via injection into a sleeve contained within the sample compartment, where the sleeve encloses the upper and lower grips and enables a construct to form attached to these grips. In a second design, a split mold is received in the bioreactor chamber, the split mold having a cavity for receiving the upper and lower grips. Tissue explants and engineered constructs can be held within these grips. Medium level in the sample compartment is controlled, and different lengths of samples can be accommodated in the sample compartment. The height of the upper grip is adjustable by raising or lowering an extension rod that passes through a dynamic seal to the environment outside the chamber. The bioreactor chamber sample compartment includes a window to permit visualization of the sample as well as light-mediated transformation of biomaterials within the sample compartment. The samples held by grips within these chambers can be subject to uniaxial mechanical stimulation. Medium is perfused around the samples, and medium may be sampled via access ports. | 11-06-2008 |
20090215104 | Bioreactor Device, and Method and System for Fabricating Tissues in the Bioreactor Device - A bioreactor device, and a method and system for fabricating tissues and growing cells and tissues in the bioreactor device, accommodates less than about 1 mL (or less than about 200 μL) of local medium volume but sample sizes of about 100 μL or greater. The bioreactor device includes a bioreactor chamber for containing a sample, where sample growth in response to mechanical, electrical, and biofactor stimulation is monitored through one or more optical ports. Embedded sensors are provided for measuring fluid pressure, pH, temperature, and oxygen tension. The bioreactor device can receive different types of mechanical loadings, including fluid shear, hydrostatic pressure, matrix compression, and clinorotation. | 08-27-2009 |
20110318414 | REGENERATIVE TISSUE GRAFTS AND METHODS OF MAKING SAME - A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (MPCs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. MPCs can be harvested from debrided muscle tissue following orthopaedic trauma. The traumatized muscle-derived progenitor cells are a readily available autologous cell source that can be utilized to effect or improve wound healing in a variety of therapeutic settings and vehicles. | 12-29-2011 |
20140288022 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME - Functionalized chondroitin sulfate, cross-linked polymer matrices comprising functionalized chondroitin sulfate, and methods of making and using the same are provided. Such polymer matrices may be used for tissue engineering, reconstructing cartilage, and the like. Kits are also provided for detection of cartilage degrading enzymes. | 09-25-2014 |
Rocky Sung Chi Tuan, Pittsburgh, PA US
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20160129155 | MUSCULOSKELETAL TISSUE FABRICATION - Described herein are methods of fabricating human cell-based engineered musculoskeletal tissues (hCEMTs) using three dimensional fabrication technology that involves injectable materials with in situ polymerization/solidification capability and/or solid free-form fabrication. Also described is the usage of hCEMTs for tissue repair and drug testing. | 05-12-2016 |
Sebastien Le Tuan US
Patent application number | Description | Published |
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20110185008 | Methods and Apparatus for Supporting and Implementing Multi-User Interactions Including Shared Display Devices - Methods and apparatus for implementing multi-user casual interactions between users, a plurality of shared display devices, and/or a plurality of third-party devices. The methods include the ability for any user, without any registration prerequisite, to enter content on a handset and to cause certain content changes to be displayed on certain shared display devices, as well as related content information to be sent back to the requesting user's handset and optionally to other users' handsets or to certain third-party devices. The methods also include the ability for an operator to use a graphical user interface to create and manage the rules that control such behavior depending, among other parameters, on the user's submissions or on other users' submissions over a period of time. The methods enable the rules to be extended in an unlimited fashion thanks to the ability to interconnect with a plurality of third-party services. | 07-28-2011 |
Te-Lin Tuan, Seattle, WA US
Patent application number | Description | Published |
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20140298298 | INTERMEDIARY FOR TESTING CONTENT AND APPLICATIONS - A test device may include an application that accesses online content. In some examples, a test intermediary and/or a test user interface (UI) are downloaded to the test device in response to a request by the application for obtaining the content from a network location. The test intermediary may be positioned to receive communications between the application and the content during testing of the content and/or the application. For example, the test intermediary may intercept metrics and other callbacks passed between the content and the application during manual or automated testing. In some instances, the test intermediary may provide the metrics and/or other test outputs for display in the test user UI rendered on the test device. The content may be rendered to be functional within the test UI, and the existence of the test intermediary and/or the test UI may be transparent to the application and the content. | 10-02-2014 |
Tim Tuan, San Jose, CA US
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20110276321 | DEVICE SPECIFIC CONFIGURATION OF OPERATING VOLTAGE - A method and circuit for device specific configuration of an operating voltage is provided. A circuit design is analyzed to determine a maximum gate-level delay for the circuit design. A minimum voltage value corresponding to the maximum gate-level delay is determined along with a default voltage value corresponding to a default gate-level delay. A voltage scaling factor corresponding to the minimum voltage and default voltage values is determined. The circuit design is synthesized such that the synthesized design includes the voltage scaling value. The synthesized design specifies setting an operating voltage to a value of a startup voltage value scaled by the voltage scaling value. | 11-10-2011 |
Vinh Le Tuan, Mississauga CA
Patent application number | Description | Published |
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20150219192 | FORCE CONVERTER APPARATUS AND METHOD - This invention relates to devices for converting a small input force to a larger output force and particularly relates to devices and methods for converting an input force to an output force comprising: an arm rotatable about an axis of rotation where the axis of rotation is moveable between first and second positions; an input force for rotating and moving the arm about the axis of rotation between the first and second positions; structure for controlling the rotation of the arm, movement and position of the axis of rotation to generate a non-circular orbital segment of the arm to transfer an output force between the first and second positions. | 08-06-2015 |
Wei-Chung Tuan, Hamburg DE
Patent application number | Description | Published |
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20140332640 | SYSTEM AND METHOD FOR MOUNTING AIRCRAFT SYSTEM COMPONENTS IN THE CROWN AREA OF AN AIRCRAFT - A system for mounting aircraft system components in the crown area of an aircraft comprising a first longitudinal carrier element, a second longitudinal carrier element and a bridging element which connects the first longitudinal carrier element to the second longitudinal carrier element. The system is mountable in the crown area of an aircraft in such a way that the first and the second longitudinal carrier elements extend substantially parallel to the longitudinal axis of the aircraft. A plurality of cable ducts for accommodating electrical lines is provided on the first and/or the second longitudinal carrier elements. | 11-13-2014 |
20150251762 | Flight attendant seat arrangement - A flight attendant seat arrangement comprises a monument which is suitable for installation in an aircraft cabin, a first receiving recess being constructed in a wall of said monument. A flight attendant seat has a backrest element and also a seat element. The backrest element and seat element are at least partially received within the first receiving recess constructed in the wall of the monument. | 09-10-2015 |
Wei Jei Tuan US
Patent application number | Description | Published |
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20090100570 | Patch for garments and other products for producing light and sound - A patch for garments and other articles for producing light and sound from the patch. The patch for garments or other articles includes a multi-layered and waterproof composite structure having a cover outer layer made from PVC film, a top layer made from molded PVC, an intermediate layer being a circuit board member and a bottom layer made from PVC film. The cover outer layer includes artwork or graphics on the PVC film of the cover outer layer. The top layer includes an interior first compartment for receiving the circuit board member therein, an interior speaker compartment for receiving a speaker member therein and an interior button compartment for receiving a push button switch therein. The circuit board member includes a battery member, an IC chip, a light assembly and a sound and speaker assembly. The light assembly includes a plurality of LED lights and a light switch having a movable element for closing the light switch in order to obtain a visual effect of blinking and/or flashing lights from the plurality of LED lights within the patch. The sound and speaker assembly includes the speaker member and the push button switch on the circuit board for producing sound effects within the patch when the switch is actuated by the user. The composite structure is fixedly attached to an outer surface of the garment or article by attaching means, such as gluing, stitching, stapling, laser welding or adhesives. | 04-23-2009 |
Yen Tuan, Kirkland, WA US
Patent application number | Description | Published |
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20100243370 | Aero-acoustic aviation engine inlet for aggressive noise abatement - An aero-acoustic aviation engine inlet with a single air blowing slot or multiple air blowing slots flows air over one or more segments of inlet acoustic lining surfaces at speeds that are higher than the inlet mean air flow speed, for aggressive inlet noise abatement. | 09-30-2010 |
20120024622 | Gaseous-fluid supply system for noise abatement application - Gaseous-fluid supply system for a general industrial power machinery application and a class of laboratory noise research and development comprises three subsystems, namely a gaseous-fluid delivery subsystem, a gaseous-fluid settling subsystem and a gaseous-fluid duct subsystem. Each subsystem must satisfy a set of fluid dynamic requirements determined by the situation in hand. For noise abatement application and research, an addition set of self-noise requirements must also be satisfied. | 02-02-2012 |
20120031501 | Aviation engine inlet with tangential blowing for buzz saw noise control - The present patent disclosure presents a class of patent aviation engine inlets using tangential blowing airflow grazing over buzz saw lining surface to prevent buzz saw noise from propagation out of the engine inlet, to alleviate airport noise problem and to reduce airplane cabin noise level for passenger comfort. The robustness of the concept of tangential blowing in the improvement of the attenuation of buzz saw tones by buss saw lining is that, practically, the significant buzz saw tones are eliminated. | 02-09-2012 |