Tsan
Alison Tsan, Castro Valley, CA US
Patent application number | Description | Published |
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20100099110 | Allele-Specific Amplification - The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having a 3′-terminal nucleotide complementary to only one variant of the target sequence and having at least one nucleotide with a base covalently modified at the exocyclic amino group, wherein the allele-specific oligonucleotide is extended by a nucleotide-incorporating biocatalyst predominantly when hybridized to the variant of the target sequence for which it has said complementary 3′-terminal nucleotide. | 04-22-2010 |
20110311968 | Allele-Specific Amplification of Nucleic Acids - The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, having an internally-placed selective nucleotide complementary to only one variant of the target sequence wherein the allele-specific oligonucleotide is extended by a nucleic acid polymerase predominantly or exclusively when hybridized to the variant of the target sequence for which it has said complementary selective nucleotide. | 12-22-2011 |
20110312040 | Preferential Amplification of mRNA Over DNA Using Chemically Modified Primers - The present invention relates to a method, oligonucleotides, reaction mixtures and kits for the selective amplification of a messenger RNA target comprising an exon-exon junction, using an oligonucleotide that comprises at least one nucleotide modified at the exocyclic amino group. | 12-22-2011 |
20120164641 | Methods and Compositions for Detecting Mutation in the Human Epidermal Growth Factor Receptor Gene - The invention comprises reagents and methods for detecting cancer-causing mutations in the human EGFR gene. Further, a method of detecting the mutations and a method of treatment are disclosed. | 06-28-2012 |
20130078630 | Use of G-Clamp for Improved Allele-SpecificPCR - The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having at least one selective nucleotide complementary to only one variant of the target sequence and incorporating at least one “G-clamp” nucleotide. | 03-28-2013 |
20130121996 | Novel Complex Mutations in the Epidermal Growth Factor Receptor Kinase Domain - Six new mutations were found in exon 19 of the EGFR gene, the exon that is often mutated in tumors. The invention comprises methods of detecting the mutations, methods of prognosis and methods of predicting response to treatment based on the presence of absence of the mutations. | 05-16-2013 |
20140242592 | Allele-Specific Amplification - The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having a 3′-terminal nucleotide complementary to only one variant of the target sequence and having at least one nucleotide with a base covalently modified at the exocyclic amino group, wherein the allele-specific oligonucleotide is extended by a nucleotide-incorporating biocatalyst predominantly when hybridized to the variant of the target sequence for which it has said complementary 3′-terminal nucleotide. | 08-28-2014 |
Alison Tsan, Danville, CA US
Patent application number | Description | Published |
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20140170650 | Primers with Modified Phosphate and Base in Allele-Specific PCR - The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having at least one selective nucleotide complementary to only one variant of the target sequence and incorporating both a nucleotide with a base covalently modified at the exocyclic amino group and a modified phosphate. | 06-19-2014 |
20140272961 | METHODS AND COMPOSITIONS FOR DETECTING MUTATIONS IN THE HUMAN PI3KCA (PIK3CA) GENE - The invention comprises reagents and methods for detecting cancer-associated mutations in the human PI3KCA (PIK3CA) gene and assessing the patients based thereon. | 09-18-2014 |
20140336056 | NON-INVASIVE EARLY DETECTION OF SOLID ORGAN TRANSPLANT REJECTION BY QUANTITATIVE ANALYSIS OF MIXTURES BY DEEP SEQUENCING OF HLA GENE AMPLICONS USING NEXT GENERATION SYSTEMS - The invention is a method of detecting or assessing solid organ graft (transplant) rejection by detecting donor-specific HLA alleles in a blood sample of a graft (transplant) recipient. The invention further comprises a method of detecting the presence of maternal cells in a blood sample of an offspring. | 11-13-2014 |
20140341884 | Novel Complex Mutations in the Epidermal Growth Factor Receptor Kinase Domain - New mutations were found in exon 19 of the EGFR gene, the exon that is often mutated in tumors. The invention comprises methods of detecting the mutations, methods of prognosis and methods of predicting response to treatment based on the presence of absence of the mutations. | 11-20-2014 |
Chih-Lung Tsan, Tu-Cheng TW
Patent application number | Description | Published |
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20090289794 | METHOD AND SYSTEM FOR MONITORING ONE OR MORE OBJECTS BY ELECTRONIC DEVICE - A method and system for monitoring one or more objects by an electronic device are provided. The method includes defining a distance threshold between the electronic device and an object having a RFID tag, calculating a distance between the electronic device and the object, and generating alerts upon detecting that the distance is greater than the distance threshold. | 11-26-2009 |
20100054463 | COMMUNICATION SYSTEM AND METHOD FOR PROTECTING MESSAGES BETWEEN TWO MOBILE PHONES - A communication system and method for protecting messages between two mobile phones are provided. The method sets protective parameters in a first mobile phone, generates an encryption key and a decryption key according to the protective parameters, stores the decryption key into a storage device of the first mobile phone, and registers the encryption key to a second mobile phone through a wireless network. The method further encrypts a short message into an encrypted message in the second mobile phone according to the encryption key, and sends the encrypted message to the first mobile phone through the wireless network. In addition, the method decrypts the encrypted message to a readable message when the first mobile phone receives the encrypted message, and displays the readable message on a display screen of the first mobile phone. | 03-04-2010 |
Jung Hui Tsan, Kaohsiung TW
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20100259041 | Pipe connecting structure - A pipe connecting structure has a slipping holding section having a reduced diameter on one end of a pipe, the slipping holding section has therein a connecting block provided with a screw rod of which the front end protrudes outwards; and the structure has a slipping holding hole provided on one end of another pipe in cooperation with the slipping holding section, the slipping holding hole also has therein a connecting block having a screw hole in cooperation with the screw rod of the former connecting block, thereby, when the two pipes are assembled with each other, not only the slipping holding section is slipped in the hollow slipping holding hole, but also the screw rod is screwed in the screw hole to make the two pipes be connected more firmly against dropping off, and to make the two pipes he connected easier and more convenient to make an effect of being stiffly erect against tilting after assembling, and the whole pipe connecting structure is more valuable in practical use. | 10-14-2010 |
Shen-Chi Tsan, Hsinchu TW
Patent application number | Description | Published |
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20120268698 | COLOR FILTER SUBSTRATE AND DISPLAY DEVICE - A color filter substrate includes a transparent substrate, a number of color photoresists disposed on the transparent substrate and a high-reflecting region disposed on the transparent substrate. The high-reflecting region at least includes a first region for separating the color photoresists. The high-reflecting region either is filled with a reflecting material or is empty. A display device is also provided. The display device includes a lower substrate, a driving circuit layer disposed on the lower substrate, a display layer disposed on the driving circuit layer and the above-mentioned color filter substrate disposed on the display layer. The color filter substrate can be assembled to the display device to increase the total light intensity of light reflection, thereby improving the display quality of the display device. | 10-25-2012 |
Yao-Chang Tsan, Taipei TW
Patent application number | Description | Published |
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20120065101 | METHODS FOR REGULATING NEURAL DIFFERENTIATION - Methods of producing populations of predominantly astrocytes, neurons or oligodendrocytes are provided. In addition, methods of treating mammals having astroglial tumors, oligodendrocyte tumors, or neuronal tumors are provided. | 03-15-2012 |
20140134738 | METHODS FOR REGULATING NEURAL DIFFERENTIATION - Methods of producing populations of predominantly astrocytes, neurons or oligodendrocytes are provided. In addition, methods of treating mammals having astroglial tumors, oligodendrocyte tumors, or neuronal tumors are provided. | 05-15-2014 |
Yee Soon Tsan, Singapore SG
Patent application number | Description | Published |
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20100268395 | SYSTEM AND METHOD FOR DETECTING PERFORMANCE - A method for monitoring the operation of a wind turbine generator comprising the steps of sampling a physical parameter related to said apparatus to produce an initial data set, conducting a statistical analysis on said initial data set to establish initial statistical values for said parameter; after a predetermined interval, re-sampling the physical parameter to create a re-sampled data set; conducting statistical analysis on the resampled data set to establish subsequent statistical values; comparing said subsequent statistical values with the initial statistical values and; selecting an action based upon said comparison. | 10-21-2010 |
20110191033 | SYSTEM FOR MONITORING A RESTORATION FACTOR OF A WIND TURBINE POPULATION - A system for monitoring the quality of maintenance performed on a wind turbine. A restoration factor is used to determine the quality of maintenance performed of the wind turbine. A restoration factor determined after a scheduled maintenance is compared to historical and comparative references to determine the quality of the maintenance performed on the wind turbine. Based upon these comparisons, maintenance of the wind turbine may be modified to increase the capacity of the wind turbine. | 08-04-2011 |