Patent application number | Description | Published |
20080261237 | Inositol-Phosphate Derivatives and Method of Detecting Inositol-1-Phosphate - The present invention relates to inositol phosphate derivatives, in which the inositol phosphate is substituted with one or two reactive groups G or one or two conjugated substances or molecules M, said reactive group(s) G or said substance(s) or molecule(s) M being linked to IP1 via a linkage group L, M being chosen from the following group: a tracer, an immunogen, a member of a binding partner pair, a solid support. | 10-23-2008 |
20090162861 | METHOD FOR SUPPRESSING A FRET SIGNAL, FRET SIGNAL SUPPRESSOR AGENTS AND USE IN A METHOD FOR MULTIPLEXING BIOLOGICAL EVENTS - The invention relates to a method for suppressing the FRET emitted by a reaction medium containing a pair of fluorescent FRET partner conjugates specific for a biological event, characterized in that a FRET signal killer which does not disturb said biological event is introduced into this medium. | 06-25-2009 |
20090215106 | METHOD FOR DETECTING INTRACELLULAR INTERACTION BETWEEN BIOMOLECULES - The present invention relates to a quantitative non-microscopic method of detecting intracellular interactions between biomolecules, on living cells, in response to a biological or pharmacological stimulation, by a time-resolved proximate energy transfer effect between two members of a fluorescence donor/acceptor pair. | 08-27-2009 |
20090220988 | METHOD OF REVEALING A BIOLOGICAL PROCESS USING A FRET MEASUREMENT - The present invention relates to a method of revealing a biological process using a FRET measurement, which comprises the following steps:
| 09-03-2009 |
20090294691 | Method for Improving the Detection of Fluorescence Signals During a Resonance Energy Transfer - The invention concerns the use of the fluorescence polarization phenomenon to improve detection of fluorescent signals during a fluorescence resonance energy transfer (FRET). In particular, the invention concerns a method for improving signal/noise ratio in a FRET measurement. The invention also concerns an apparatus for measuring fluorescence following an energy transfer between a donor fluorescent compound and an acceptor fluorescence compound in a measurement medium. | 12-03-2009 |
20110236952 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF - The invention relates to compounds of formula (I′): | 09-29-2011 |
20120009599 | METHOD FOR DETECTING MEMBRANE PROTEIN INTERNALIZATION - A method for detecting the internalization of a transmembrane protein of interest expressed at the surface of a cell, comprising the following steps:
| 01-12-2012 |
20120115176 | METHOD FOR DETECTING COMPOUNDS MODULATING DIMERS OF VFT DOMAIN MEMBRANE PROTEINS - The invention relates to a method for selecting compounds having a modulating effect on the activation state of a dimer of VFT-domain proteins expressed in cell membranes present in a measuring medium, said dimer consisting of a first protein and of a second protein, said proteins being identical or different, wherein this method comprises the following steps:
| 05-10-2012 |
20120190048 | METHOD FOR DETERMINING THE BINDING OF A GIVEN COMPOUND TO A MEMBRANE RECEPTOR - The invention relates to a method for determining whether a test compound binds preferentially to a membrane receptor R1 or to a membrane receptor R2, these receptors being known to be expressed on the surface of the cells in monomeric, homodimeric or heterodimeric form. This method is applied using one or two FRET partner pairs. | 07-26-2012 |