Patent application number | Description | Published |
20090023777 | Substituted 4-amino-benzylpiperidine compounds - This invention provides 4-amino-1-benzylpiperidine and related compounds and pharmaceutically acceptable salts thereof which are useful as muscarinic receptor antagonists. This invention also provides pharmaceutical compositions containing such compounds; processes and intermediates useful for preparing such compounds; and methods for treating disease conditions mediated by muscarinic receptors, such as overactive bladder, irritable bowel syndrome, asthma and chronic obstructive pulmonary disease, using such compounds. | 01-22-2009 |
20090048299 | Biphenyl compounds useful as muscarinic receptor antagonists - This invention provides compounds of formula I: | 02-19-2009 |
20090239904 | COMPOUNDS HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY - This invention provides compounds of formula I: | 09-24-2009 |
20100197667 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS - The invention provides compounds of formula I: | 08-05-2010 |
20110198240 | Sensors and Methods for Detecting Organic Carbonyl Species - A method for detecting an organic carbonyl species involves exposing a metal oxide-free film of a polyaniline to an environment suspected of containing an organic carbonyl species, detecting a change in electrical conductivity and/or an optical or luminescent property of the polyaniline, and, correlating the change in electrical conductivity and/or optical or luminescent property to a presence of the organic carbonyl species in the environment. Further, sensors for organic carbonyl species are disclosed having a metal oxide-free film of a polyaniline supported on an electrically insulating substrate. The method and sensors provide a good balance between response time and sensitivity, being considerably faster than metal oxide and metal oxide/polymer based sensors, while having greater sensitivity than other polymer-based sensors. | 08-18-2011 |
20110223688 | GRATING-BASED EVANESCENT FIELD MOLECULAR SENSOR USING A THIN SILICON WAVEGUIDE LAYER - A technique for high sensitivity evanescent field molecular sensing employs a detection scheme that simultaneously couples a polarized beam to a single mode of a waveguide, and couples the polarized beam out of the waveguide to specularly reflect the beam by the same grating. Strong interaction with the single (preferably TM) mode is provided by using a silicon on insulator (SOI) wafer having a waveguide thickness chosen between 10-400 nm so that the majority of the mode field strength spans the evanescent field. Well known, robust techniques for producing a grating on the waveguide are provided. Interrogation from a backside of the SOI wafer is taught. | 09-15-2011 |
20110281851 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS - The invention provides compounds of formula I: | 11-17-2011 |
20120122850 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS - The invention provides compounds of formula I: | 05-17-2012 |