Patent application number | Description | Published |
20090088652 | Physiological sensor placement and signal transmission device - A garment is used to facilitate the placement of biomedical sensors or other electrodes on the body. The garment is comfortable and allows freedom of movement much like typical clothing. Textile based electrical components are included in the garment which are capable of transmitting an electrical signal to and from various external electrodes placed on the body. A textile based EMI shield protects the signals from electromagnetic interference. The garment may take any form such as a vest, sports bra, long sleeve shirt, bonnet, or other form and may provide access to an electrode placement site without requiring removal of the garment. | 04-02-2009 |
20090149084 | Biomedical Electrode Connectors - A biomedical electrode connector for coupling with a biomedical electrode of the type including an electrode base and a male terminal projecting from the electrode base is provided. | 06-11-2009 |
20090270709 | Novel Electrodes - The present disclosure provides electrodes that possess components capable of indicating to an end-user when the electrode is in need of replacement. In embodiments, the electrodes include a hydrogel in combination with a pH indicator which changes its color or opacity upon repeated use of the electrode, thereby indicating an appropriate time for changing or replacing the electrode. | 10-29-2009 |
20090270710 | Novel Electrodes - The present disclosure provides electrodes that possess components capable of indicating to an end-user when the electrode is in need of replacement. | 10-29-2009 |
20100204752 | Negative Pressure and Electrostimulation Therapy Apparatus - A negative wound pressure therapy apparatus includes a wound dressing for defining a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around wound tissue. The apparatus also includes a fluid conduit in fluid communication with the reservoir. The fluid conduit defines a fluid flow path for carrying fluids from the reservoir. The apparatus also includes a vacuum source in fluid communication with the fluid conduit. The vacuum source is suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. The apparatus also includes at least one biomedical electrode mounted with respect to the wound dressing for transmitting electrical energy to stimulate healing of the wound tissue. | 08-12-2010 |
20100266671 | Device and Method for Treating Dermal Tissue - The present disclosure provides gel compositions useful for treating the skin. The gel compositions are hydrogels that include from about 33 wt % to about 68 wt % of a humectant or a mixture of humectants; about 0 wt % to about 8 wt % of an electrolyte or mixture of electrolytes; from about 2 wt % to about 20 wt % of water; from about 18 wt % to about 45 wt % of a copolymer. The copolymer includes, in polymerized form, from about 80 mol % to about 95 mol % of a first monomer, which is a mixture of acrylic acid and a salt thereof, from about 5 mol % to 20 mol % of a second monomer, which can be a salt of 2-acrylamido-2-methylpropane sulfonic acid, and, optionally a crosslinking agent. In embodiments, the gel composition has a pH of about 7.0 or less. The dermal patches of the present disclosure may be utilized in skin care, and may include the application of the patch, its removal, and re-application to tissue. | 10-21-2010 |
20110117793 | Biomedical Electrode Connectors - A biomedical electrode connector for coupling with a biomedical electrode of the type including an electrode base and a male terminal projecting from the electrode base is provided. | 05-19-2011 |
20110230925 | Electrode Delivery System - According to an aspect of the present disclosure, an automatic external defibrillator configured to deliver electrical pulses and/or shocks to a heart of a patient during a cardiac emergency is provided and includes a housing supporting an electrical connector; a defibrillator electrode delivery system supported on the housing; and a pair of defibrillation electrode pads supported by the defibrillator electrode delivery system. Each of the pair of defibrillation electrode pads is pre-connected to the electrical connector of the housing. A hydrogel layer of each defibrillation electrode pad is retained by the defibrillator electrode delivery system in such a manner so as to reduce a moisture vapor transmission rate thereof. | 09-22-2011 |
20120037526 | STORAGE AND DISPENSING SYSTEM FOR REUSABLE SYRINGE - A storage and dispensing container includes a base having an open end and a receptacle. A first divider is secured in the receptacle. A second divider is pivotally secured to the first divider, and defines a first compartment with the first divider. The first compartment has a size that is selectively adjustable by pivoting the second divider relative to the first divider. | 02-16-2012 |
20120041296 | Medical Electrode - The present disclosure provides electrodes that possess hydrogels for contacting skin. In embodiments, an electrode of the present disclosure may include a substrate and a conductive composition on at least a portion of a surface of the substrate, the conductive composition including at least one hydrogel and at least one component capable of providing either a cooling or warming sensation upon contact with tissue of a patient. Methods for forming these hydrogels and electrodes are also provided. | 02-16-2012 |
20120041384 | SINGLE USE DEVICE FOR DELIVERY OF CARTRIDGE DRUGS - A syringe for administering medicament from a cartridge. The syringe includes a sleeve having an interior for receiving the cartridge extending between a distal hub and a proximal opening. The syringe has a cap selectively covering the proximal opening for retaining the cartridge in the interior of the sleeve. The cap includes a finger grip extending outward from the sleeve for engaging fingers of a user. The syringe also has a plunger rod movably connected to the cap. The plunger rod has a distal connector for selectively connecting the rod to the cartridge plunger when the cartridge is received in the interior of the sleeve to push medicament from the cartridge reservoir as the plunger rod moves with respect to the cap. | 02-16-2012 |
20120226129 | ECG Lead Wire Organizer And Dispenser - An ECG lead set including an ECG electrode assembly and a lead set hub. ECG electrode includes at least one electrode configured to receive biopotential signals from a patient, a plug connector for connecting said ECG electrode assembly, a web, connected between the at least one electrode and the plug connector and configured to form an electrical connection therebetween. The lead set hub includes at least one receptacle configured to receive the plug connector of the ECG electrode assembly. | 09-06-2012 |
20120226131 | ECG Lead Wire Organizer And Dispenser - An ECG lead set including an ECG electrode assembly and a lead set hub. ECG electrode includes at least one electrode configured to receive biopotential signals from a patient, a plug connector for connecting said ECG electrode assembly, a web, connected between the at least one electrode and the plug connector and configured to form an electrical connection therebetween. The lead set hub includes at least one receptacle configured to receive the plug connector of the ECG electrode assembly. | 09-06-2012 |
20120226177 | ECG LEAD WIRE ORGANIZER AND DISPENSER - An ECG lead set including an ECG electrode assembly and a lead set hub. ECG electrode includes at least one electrode configured to receive biopotential signals from a patient, a plug connector for connecting said ECG electrode assembly, a web, connected between the at least one electrode and the plug connector and configured to form an electrical connection therebetween. The lead set hub includes at least one receptacle configured to receive the plug connector of the ECG electrode assembly. | 09-06-2012 |
20120258421 | Anesthetic Syringe - A syringe assembly for dispensing medicine from a cartridge having a diaphragm and a piston opposite the diaphragm. The assembly includes a barrel having a hollow interior, an open proximal end, a closed distal end, and an outlet. The assembly also includes a cartridge receiver slidably receivable in the hollow interior of the barrel. The receiver includes an interior space for receiving the cartridge, an access needle extending into the interior space for puncturing the diaphragm of the cartridge. The access needle directs fluid to the barrel outlet. The cartridge receiver includes a plunger rod movable into the interior space of the cartridge receiver for engaging the piston of the cartridge to selectively force medicine in the cartridge through the access needle. | 10-11-2012 |
20120259287 | Medical Cartridge Receiver Having Access Device - A needle and receiver assembly for use with a syringe cartridge filled with medicine. The assembly includes a cartridge receiver having a hollow interior, an open end sized for receiving at least part of the syringe cartridge, and a closed end opposite the open end. The assembly includes a needle mounted on the receiver having a fluid passage extending between a sharp delivery tip at a distal end of the needle and a sharp access tip at a proximal end of the needle opposite the delivery tip, the needle extending through the closed end of the receiver so the access tip is positioned inside the hollow interior of the receiver and the delivery tip is positioned outside the receiver. The assembly includes a cutter movably mounted in the hollow interior of the receiver for cutting the diaphragm of the cartridge when received in the hollow interior of the receiver. | 10-11-2012 |
20130066186 | Novel Electrodes - The present disclosure provides electrodes that possess components capable of indicating to an end-user when the electrode is in need of replacement. The electrode includes a substrate and a conductive composition on at least a portion of a surface of the substrate. In embodiments, the conductive composition includes at least one hydrogel and at least one component that precipitates from the hydrogel after repeated use of the electrode, thereby providing an indication to replace the electrode. In other embodiments, the electrodes include a hydrogel in combination with a pH indicator which changes its color or opacity upon repeated use of the electrode, thereby indicating an appropriate time for changing or replacing the electrode. | 03-14-2013 |
20130072777 | Physiological Sensor Placement and Signal Transmission Device - A garment is used to facilitate the placement of biomedical sensors or other electrodes on the body. The garment is comfortable and allows freedom of movement much like typical clothing. Textile based electrical components are included in the garment which are capable of transmitting an electrical signal to and from various external electrodes placed on the body. A textile based EMI shield protects the signals from electromagnetic interference. The garment may take any form such as a vest, sports bra, long sleeve shirt, bonnet, or other form and may provide access to an electrode placement site without requiring removal of the garment. | 03-21-2013 |
20130172838 | Negative Pressure and Electrostimulation Therapy Apparatus - A negative wound pressure therapy apparatus includes a wound dressing for defining a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around wound tissue. The apparatus also includes a fluid conduit in fluid communication with the reservoir. The fluid conduit defines a fluid flow path for carrying fluids from the reservoir. The apparatus also includes a vacuum source in fluid communication with the fluid conduit. The vacuum source is suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. The apparatus also includes at least one biomedical electrode mounted with respect to the wound dressing for transmitting electrical energy to stimulate healing of the wound tissue. | 07-04-2013 |
20130245567 | Safety Catheter and Needle Assembly - An intravenous catheter and safety needle assembly is disclosed which includes a catheter assembly, a needle assembly and a needle guard. The needle guard is supported within a hub of the catheter and is positioned to engage an enlarged diameter portion of a needle of the needle assembly during withdrawal of the needle from the catheter assembly to effect an inversion of the needle guard about a sharpened tip of the needle. | 09-19-2013 |
20130289689 | ELECTRODE DELIVERY SYSTEM - An automatic external defibrillator configured to deliver electrical pulses and/or shocks to a heart of a patient during a cardiac emergency includes a housing supporting an electrical connector; a defibrillator electrode delivery system supported on the housing and a pair of defibrillation electrode pads supported by the defibrillator electrode delivery system. Each of the pair of defibrillation electrode pads is pre-connected to the electrical connector of the housing. A hydrogel layer of each defibrillation electrode pad is retained by the defibrillator electrode delivery system in such a manner so as to reduce a moisture vapor transmission rate thereof. | 10-31-2013 |
20130303927 | ECG LEAD SET AND ECG ADAPTER SYSTEM - A method for coupling an ECG monitor with an incompatible ECG lead set includes the steps of providing an ECG adapter including an adapter body having at least one monitor connector adapted for coupling to an input of an ECG monitor and at least one lead set receptacle adapted for coupling to a connector of an ECG lead set incompatible with the input of the ECG monitor, coupling the at least one monitor connector of the adapter body with the input of the ECG monitor and coupling the at least one lead set receptacle of the adapter body with the connector of the ECG lead set to thereby electrically couple the ECG lead set with the ECG monitor. | 11-14-2013 |
20140065248 | MEDICAL ELECTRODE - The present disclosure provides electrodes that possess hydrogels for contacting skin. In embodiments, an electrode of the present disclosure may include a substrate and a conductive composition on at least a portion of a surface of the substrate, the conductive composition including at least one hydrogel and at least one component capable of providing either a cooling or warming sensation upon electrical stimulation. Methods for forming these hydrogels and electrodes are also provided. | 03-06-2014 |
20140180054 | ECG LEAD WIRE ORGANIZER AND DISPENSER - An ECG lead set including an ECG electrode assembly and a lead set hub. ECG electrode includes at least one electrode configured to receive biopotential signals from a patient, a plug connector for connecting said ECG electrode assembly, a web, connected between the at least one electrode and the plug connector and configured to form an electrical connection therebetween. The lead set hub includes at least one receptacle configured to receive the plug connector of the ECG electrode assembly. | 06-26-2014 |
20140296826 | PREPARATION PATCH AND SAFETY SYRINGE SYSTEM - A safety syringe system including a safety syringe and an injection site preparation patch adapted for use with the safety syringe. The safety syringe includes a syringe body and a safety shield slidably disposed about the syringe body. The injection site preparation patch has a tissue-facing side and a syringe-facing side, and may include a substrate, a syringe adhesive layer adapted to adhere to a distal flange of the safety shield, a hydrogel layer adapted to adhere to tissue, and removable release liners disposed on either side. The patch may include a medicament, anesthetic, or a thermal compound. Adhesion between the patch and the flange is less than adhesion between the patch and tissue, so that the patch adheres to the shield with sufficient strength to enable the shield to slide over the needle upon withdrawal, but with insufficient strength to cause the patch to pull away from a patient's skin. | 10-02-2014 |
20140317899 | STORAGE AND DISPENSING SYSTEM FOR REUSABLE SYRINGE - A storage and dispensing container includes a base having an open end and a receptacle. A first divider is secured in the receptacle. A second divider is pivotally secured to the first divider, and defines a first compartment with the first divider. The first compartment has a size that is selectively adjustable by pivoting the second divider relative to the first divider. | 10-30-2014 |
20140343513 | Safety Needle Assembly - A safety needle assembly is disclosed which includes a a needle assembly and a needle guard. The needle guard is supported about a needle of the needle assembly and is positioned to engage an enlarged diameter portion of the needle during withdrawal of the needle guard from the needle to effect an inversion of the needle guard about a sharpened tip of the needle. | 11-20-2014 |
20150038914 | Medical Cartridge Receiver Having Access Device - A needle and receiver assembly for use with a syringe cartridge filled with medicine includes a cartridge receiver having a hollow interior, an open end sized for receiving at least part of the syringe cartridge, and a closed end opposite the open end. The assembly includes a needle mounted on the receiver having a fluid passage extending between a sharp delivery tip at a distal end of the needle and a sharp access tip at a proximal end of the needle opposite the delivery tip positioned inside the hollow interior of the receiver. The assembly includes a cutter movably mounted in the hollow interior of the receiver for cutting the diaphragm of the cartridge when received in the hollow interior of the receiver. | 02-05-2015 |
20150073352 | SINGLE-USE DEVICE FOR INJECTION OF CARTRIDGE DRUGS - The disclosed embodiment relates to an injection device that is a single patient use, disposable device containing a needle and a cartridge containing a drug, pharmaceutical product or other injectable agent. The device is initially provided in a pre-armed state in a first engagement configuration wherein the needle is separated from the septum of a cartridge. To arm the injection device, the professional urges the device from the first engagement or pre-armed configuration to a second engagement or aimed configuration wherein the needle pierces the septum and provides a sterile fluid path to the drug, pharmaceutical product or other injectable agent contained within the cartridge. The disclosed embodiment is particularly adaptable to dental anesthetic applications, as well as other medical and veterinary applications. | 03-12-2015 |
Patent application number | Description | Published |
20080269272 | CYCLOPAMINE ANALOGUES AND METHODS OF USE THEREOF - The present invention provides compositions and methods for modulating smoothened-dependent pathway activation. The present invention provides analogs of cyclopamine that can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, Ptc loss-of-function or smoothened gain-of-function mutations. The compounds of the present invention are particularly useful in treating cancers. | 10-30-2008 |
20110166353 | Cyclopamine Analogues and Methods of Use Thereof - The present invention provides compositions and methods for modulating smoothened-dependent pathway activation. The present invention provides analogs of cyclopamine that can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, Ptc loss-of-function or smoothened gain-of-function mutations. The compounds of the present invention are particularly useful in treating cancers. | 07-07-2011 |
20110230509 | METHODS OF USE FOR CYCLOPAMINE ANALOGS - The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: | 09-22-2011 |
20120015934 | CYCLOPAMINE LACTAM ANALOGS AND METHODS OF USE THEREOF - The present invention relates to steroidal alkaloids useful in the treatment of hedgehog pathway related disorders, particularly cancer. | 01-19-2012 |
20120065218 | Heterocyclic Cyclopamine Analogs and Methods of Use Thereof - The present invention relates to steroidal alkaloids that can be used in the treatment of hedgehog pathway related disorders, particularly cancer. | 03-15-2012 |
20120077834 | Methods of Use of Cyclopamine Analogs - The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: | 03-29-2012 |
20130029982 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 01-31-2013 |
20130029984 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 01-31-2013 |
20130053362 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. | 02-28-2013 |
20130108582 | METHODS OF USE OF CYCLOPAMINE ANALOGS | 05-02-2013 |
20130267521 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 10-10-2013 |
20140100214 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. | 04-10-2014 |
20140107142 | METHODS OF USE OF CYCLOPAMINE ANALOGS - The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: | 04-17-2014 |
20140288048 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. | 09-25-2014 |
20140371253 | Cyclopamine Analogs - The invention provides novel derivatives of cyclopamine having the following formula: | 12-18-2014 |