Patent application number | Description | Published |
20110268804 | TARGETING OF ANTIGEN PRESENTING CELLS WITH IMMUNONANOTHERAPEUTICS - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface. The nanocarriers are capable of targeting antigen presenting cells when administered to a subject. The invention provides pharmaceutical compositions comprising nanocarriers. The present invention provides methods of designing, manufacturing, and using nanocarriers and pharmaceutical compositions thereof. | 11-03-2011 |
20110268805 | ADJUVANT INCORPORATION IN IMMUNONANOTHERAPEUTICS - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is an adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. | 11-03-2011 |
20120087890 | IMMUNONANOTHERAPEUTICS THAT PROVIDE IgG HUMORAL RESPONSE WITHOUT T-CELL ANTIGEN - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides synthetic nanocarriers capable of eliciting an immune system response in the form of antibody production, wherein the nanocarriers lack any T cell antigens. In some embodiments, the invention provides nanocarriers that comprise an immunofeature surface, which provides high avidity binding of the nanocarriers to antigen presenting cells. The invention provides pharmaceutical compositions comprising such nanocarriers. The present invention provides methods of designing, manufacturing maceutical compositions thereof. | 04-12-2012 |
20130129790 | Adjuvant Incorporation in Immunonanotherapeutics - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is an adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. | 05-23-2013 |
20130309270 | VACCINES COMPRISING BISPHOSPHONATE AND METHODS OF USE THEREOF - The present invention demonstrates that bisphosphonates have an intrinsic adjuvant activity and directly stimulate B cell antibody secretion. Accordingly, the present invention provides vaccines comprising a bisphosphonate, methods for stimulating an immune response, enhancing the immunogenicicty of an immunogen, and methods of treating an infection, an autoimmune disease, an allergy, and/or a cancer using the same. | 11-21-2013 |
20140037736 | Targeting of Antigen Presenting Cells With Immunonanotherapeutics - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface. The nanocarriers are capable of targeting antigen presenting cells when administered to a subject. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. | 02-06-2014 |
20140127301 | Adjuvant Incorporation in Immunonanotherapeutics - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. | 05-08-2014 |
Patent application number | Description | Published |
20120046972 | METHOD AND SYSTEM FOR MANAGING AND DISPLAYING MEDICAL DATA - The invention relates to a medical data management method and system wherein medical data ( | 02-23-2012 |
20120265075 | METHOD OF TRANSFORMING A DOPPLER VELOCITY DATASET INTO A VELOCITY VECTOR FIELD - A method and device for transforming a Doppler velocity dataset into a velocity vector field, the including: (a) providing a 2D or 3D Doppler velocity dataset, acquired by means of 2D or 3D ultrasonography from an object; b) calculating a velocity vector field by assuming the velocity at each point of the dataset to be the sum of the provided Doppler velocity and an additional vector field derived from an irrotational flow velocity, and by assuming the velocity vector field to be mathematically continuous, therefore solving an elliptical equation of the Poisson type. | 10-18-2012 |
20140169645 | METHOD AND SYSTEM FOR MEDICAL IMAGING DATA MANAGEMENT - A method and a corresponding system and medical data repository for medical imaging data management including: receiving medical images associated with an exam of a patient; storing the medical images; receiving clinical information derived from the medical images; arranging the clinical information in a database structured to allow retrieval of such clinical information independently from the retrieval of the stored medical images. | 06-19-2014 |
20140172452 | SYSTEM FOR PROCESSING MEDICAL DATA - A system for processing medical data including: a central unit in communication with a storage of medical data, such central unit being controllable by at least a user of the system and at least one client unit, remote from the central unit, for communicatively coupling to the central unit and/or storage through at least a network, such client unit having an interface for allowing a user to interact with the system. Where the central unit is configured for remotely processing data of the storage, or causing the data to be processed by a dedicated elaboration unit coupled to such central unit and/or the storage, according to requests generated by the client unit and sending data to the client unit, and where the client unit is configured to locally interact with the data sent by the central unit to provide further requests to the central unit to iteratively process data of the storage according to user needs. | 06-19-2014 |
Patent application number | Description | Published |
20090124770 | Supported Metal Alkyl Compound and Process for the Polymerization of Olefins in Its Presence - The present invention relates to pulverulent solids obtainable by reaction of a metal alkyl compound of a divalent or higher-valent metal and a finely divided support which on its surface bears functional groups which can form a chemical bond between the metal atom of the metal alkyl compound and the surface of the support, wherein the particles of the finely divided support have particle diameters of less than 1000 nm and less than 5% by weight of the metal alkyl compound is extractable in a single extraction of the pulverulent solid with 20 ml of heptane per gram of solid at 50° C. In addition, the invention relates to a process for preparing the pulverulent solids, a catalyst composition for the polymerization of olefins which comprises the pulverulent solids and polymerization processes using the catalyst composition. | 05-14-2009 |
20100121011 | 1-BUTENE PROPYLENE COPOLYMER COMPOSITIONS - A 1-butene/propylene copolymer composition having a content of propylene derived units from 1 to 4% by weight, wherein at least 50% of the crystalline polymer is present in the thermodynamically stable, trigonal Form I (detected by DSC analysis) after 100 hours of the first melting at room temperature comprising: b) from 5% by weight to 95% by weight of an atactic 1-butene propylene copolymer having the following features: i) distribution of molecular weight Mw/Mn equal to or lower than 4; ii) no enthalpy of fusion detectable at a differential scanning calorimeter (DSC); and iii) infrared crystallinity lower than 0.5%; b) from 5% by weight to 95% by weight of an isotactic 1-butene propylene copolymer having the following features: isotactic pentads (mmmm) measured by C-NMR, higher than 80%; i) ii) melting point (Tm(II)) higher than 70° C.; and iii) distribution of molecular weight Mw/Mn equal to or lower than 4. | 05-13-2010 |
20100121015 | 1-BUTENE PROPYLENE COPOLYMER COMPOSITIONS - A 1-butene/propylene copolymer composition having a content of propylene derived units from 4 to 10% by weight, wherein at least 50% of the polymer is present in the thermodynamically stable, trigonal form 1 after 100 hours at room temperature, said composition comprising:
| 05-13-2010 |