Ton
Ton Baltissen, Heelsum NL
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20140259909 | GROWTH SUBSTRATE FOR PLANTS - A growth substrate for plants including polylactic acid, wherein the polylactic acid is particulate polylactic acid foam. A method for preparing a growth substrate for plants including polylactic acid foam, the method including providing particulate expandable polylactic acid and exposing the particulate expandable polylactic acid to predetermined temperature and pressure conditions to obtain particulate polylactic acid foam. | 09-18-2014 |
Ton Bisseling, Ede NL
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20100138962 | USE OF PLANT CHROMATIN REMODELING GENES FOR MODULATING PLANT ARCHITECTURE AND GROWTH - The present invention relates to the field of transgenic plants having modified growth and to the use of chromatin remodeling genes, in particular | 06-03-2010 |
Ton Bolhaar, Bp Ophemert NL
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20150253514 | MANUFACTURE AND TESTING OF FIBER OPTIC CASSETTE - A double flexible optical circuit includes: a flexible substrate supporting a plurality of optical fibers; a first connector terminating the optical fibers at a first end of the double flexible optical circuit; and a second connector terminating the optical fibers at a second end of the double flexible optical circuit. Each of the optical fibers is positioned in one of a plurality of separate extensions formed by the flexible substrate as the optical fibers extend from the first connector to the second connector. The first and second connectors are configured to be tested when the first and second connectors are connected through the double flexible optical circuit. The double flexible optical circuit is configured to be divided in half once the testing is complete to form two separate flexible optical circuits. | 09-10-2015 |
20150260927 | FIBER OPTIC CASSETTE - A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at non-conventional connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the non-conventional connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the non-conventional connectors adjacent the front of the body includes a ferrule, a ferrule hub supporting the ferrule, and a split sleeve surrounding the ferrule. | 09-17-2015 |
Ton Bolhaar, Ophemert NL
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20130272658 | MULTI-MODE MULTI-FIBER CONNECTION WITH EXPANDED BEAM - A method and system using GRIN fibers with a large core radius (such as twice that of the optical fibers which the GRIN fibers are used to interconnect) to expand incident beam are disclosed. In certain examples, the GRIN fibers expand the incident beams to near-collimation. In certain examples, the beam expansion reduces the connection's sensitivity (i.e., power attenuation) to lateral displacement between the optical fibers at the cost of increased sensitivity to angular misalignment between the fibers. With certain fiber connection hardware that provides precision angular alignment, beam expansion provides improved connection performance. In certain examples, a multi-fiber connector module (such as MPO), with MT-style ferrules, is used to interconnect multiple fiber pairs, each with GRIN fiber endings. In certain examples, the near-collimation of the incident beams allows efficient transmission between fibers without the need for physical contact between the fibers. | 10-17-2013 |
Ton Colijn, Nieuwendijk NL
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20150336194 | SELECTIVE SOLDERING SYSTEM - The invention relates to a selective soldering plant for the soldering of electronic circuit boards, at least one container for liquid solder, a soldering arrangement with at least one soldering nozzle and at least one pump for conveying the liquid solder to the soldering arrangement being provided, an inner shielding device for at least partially shielding the soldering arrangement upwardly with regard to a gas flow being provided above the soldering arrangement, and an inflow device being provided, through which gas, in particular protective gas, can in any event flow into the region below the inner shielding device. It is proposed that an outer shielding device for at least partially shielding the inner shielding device upwardly with regard to a gas flow be provided. | 11-26-2015 |
Ton Hoogstraaten, Neer NL
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20100272309 | Electrostatic Speaker Systems and Methods - An electrostatic speaker system including at least one electrostatic speaker element having a pair of stators and a diaphragm therebetween, each of the stators and the diaphragm having an least one electrically conductive portion. The conductive portion of the diaphragm is patterned as a mesh, which may include gaps, and a conforming layer overlying the conducting portion of the diaphragm and disposed so as to cover gaps in the mesh. A speaker drive circuit provides soft clipping of the audio input signal so that the audio signal applied between the diaphragm and the stators does not exceed the maximum acceptable level that can be applied between the diaphragm and the stators of at least one speaker element. | 10-28-2010 |
Ton Ickenroth, Heythuysen NL
Ton Karsmakers, Oss NL
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20100136822 | CABLE CLAMP - The invention concerns a Cable clamp for a cable connector, the cable clamp being arranged for receiving and capturing a portion of at least one cable extending along an extension direction from the connector. The cable clamp includes a first section and a plurality of second sections which are movably attached or attachable to the first section; the first section includes at least one through-hole extending in the direction of extension, which through-hole is configured for receiving a first portion of at least one cable penetrating through the hole and at least a portion of the second sections is arranged for capturing between them a second portion of the at least one cable penetrating through the hole and extending therefrom. | 06-03-2010 |
20100285688 | CABLE CONNECTOR AND CABLE CLAMP - Cable connector including a connector housing and a cable clamp for clamping a cable to the housing. The cable clamp having an intermediate portion between a first and a second mounting portion. At least one of the two mounting portions of the cable clamp is provided with locking means selectively cooperative with at least two matching locking means, such as slots, of the connector housing to hold the cable clamp in respective different positions corresponding to different cable diameters. | 11-11-2010 |
20110250782 | TERMINAL BLOCK FOR A CABLE CONNECTOR - Terminal block for a cable connector including insulation displacement contact slots at both sides wherein at least a part of the insulation displacement contact slots at one side of the terminal block are paired either by a corresponding insulation displacement contact slot or by a punch support at the opposite side of the terminal block. The punch supports can be provided with a cylindrical curvature with a radius corresponding to the radius of a cable to be punched. | 10-13-2011 |
Ton Karsmakers, Zd Oss NL
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20120138356 | Shielding Shell for a Connector - A Shielding shell for a connector is disclosed which includes a first wall, a second wall and a third wall. The first wall, the second wall and the third wall are arranged mutually at an angle to each other. At least the first wall and the second wall are connected to each other by a first folded edge. The shielding shell further includes a first contact portion connected with the second wall by a second folded edge, the first contact portion being arranged substantially parallel to the third wall and including a plurality of contact segments contacting said third wall. | 06-07-2012 |
Ton Kroezen, Limbricht NL
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20120095171 | BROADENING THE MOLECULAR WEIGHT DISTRIBUTION OF POLYOLEFINS MATERIALS MADE IN HORIZOR - An olefin polymerization process comprises gas-phase polymerization of at least one olefin monomer in more than one polymerization zones in one or more polymerization reactors using a high activity catalyst injected in the front end of the reactor to give solid polymer particles. According to the process of the invention, different hydrogen to olefin ratios are applied to the reactor leading to the production of very different molecular weights and therefore broadening the molecular weight distribution of the polymer produced. | 04-19-2012 |
Ton La, Jr., Houston, TX US
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20080303211 | Three-dimensional logical cube - A three-dimensional logical cube has 6 faces in the same configuration of Rubik's Cube (trademark). A three-dimensional logical cube has an N×N array of cells on each face. Each cell on a three-dimensional logical cube has a numerical value, solid and hollow dots, solid dots, or shapes, on it. A 2×2×2 cube has four numbers from 1 to 4 on its face; a 2×2×2 cube has two solid dots and two hollow dots with the same color on its face (2×2×2 alternate embodiment); a 2×2×2 cube has 1 dot to 4 dots on its cell (2×2×2 alternate embodiment); a 2×2×2 cube have same kind of shape on its face (2×2×2 alternate embodiment); a 3×3×3 cube has nine combination numbers between 1 to 12 on its face; a 3×3×3 cube has nine numbers from 1 to 9 on its face (3×3×3 alternate embodiment); a 3×3×3 cube has either a blank cell or a dot on its face (3×3×3 alternate embodiment); a 3×3×3 cube have same kind of shape on its face (3×3×3 alternate embodiment); a 4×4×4 cube has sixteen numbers from 1 to 16 on its face; and a 5×5×5 cube has twenty-five numbers from 1 to 25 on its face; The present three-dimensional logical cube when successfully solved, for numerical cell cubes, all six faces, and nine rows (six rows for 3×3×3 cubes) of adjacent cells located on four adjacent faces (two adjacent faces for 2×2×2 cube and three adjacent faces for 3×3×3 alternate embodiment) will have difference numerical numbers on its cell (no two numbers are alike); for shape cube, all six faces will have same shape for each cell on the same face; for solid and hollow dot cube, any faces will have the two solid dots and two hollow dots on its for all six faces; for solid only dot cube (3×3×3), any two opposite faces will have total of seven dots for all six faces; and solid only dot (2×2×2), each cell on the same face has 1 dot, 2 dots, 3 dots and 4 dots for all six faces, and four adjacent cells located around two faces will have 1 dot, 2 dots, 3 dots and 4 dots on its cell. The present three-dimensional logical cube is more challenging than the Rubik's Cube (trademark) with 2×2×2 the simplest logical cube to 3×3×3 challenge, 4×4×4 more challenge, and 5×5×5 which is the most challenge logical cube to solve. | 12-11-2008 |
Ton Lin, Mission Viejo, CA US
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20160038654 | SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND METHODS FOR TREATING OCULAR VASCULOPATHIES - Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat one or more ocular conditions, such as an ocular vasculopathy or glaucoma, among others. | 02-11-2016 |
Ton Logtenberg, Driebergen NL
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20090017521 | Chimaeric phages - The invention relates to the field of generating helper phages and phage display libraries for the identification of binding molecules. The invention provide chimaeric phages having a coat comprising a protein mixture. The protein mixture comprises a fusion protein having a proteinaceous molecule fused to a functional form of a phage coat protein and a mutant form of the phage coat protein, wherein the mutant form is impaired in binding to a host cell receptor. The invention further provides new phage collections, novel helper phages and methods and means for producing chimaeric phages, infectious phages and helper phages. | 01-15-2009 |
20090263864 | Recombinant production of mixtures of antibodies - The invention provides methods for producing mixtures of antibodies from a single host cell clone, wherein, a nucleic acid sequence encoding a light chain and nucleic acid sequences encoding different heavy chains are expressed in a recombinant host cell. The recombinantly produced antibodies in the mixtures according to the invention suitably comprise identical light chains paired to different heavy chains capable of pairing to the light chain, thereby forming functional antigen-binding domains. Mixtures of the recombinantly produced antibodies are also provided by the invention. Such mixtures can be used in a variety of fields. | 10-22-2009 |
20100021881 | Peptide combos and their uses - The invention provides reagents and methods for the accurate quantification of proteins in complex biological samples. Quantification is obtained by adding to a sample a peptide combo, which is essentially a collection of synthetic reference peptides. The synthetic reference peptides have a small mass difference when compared to the biological reference peptides that originate upon digestion from the proteins present in the sample. Reference peptides and synthetic reference peptides are selected and the identity and accurate amounts of reference peptides are determined by mass spectrometry. The methods can be used in high throughput assays to interrogate proteomes. | 01-28-2010 |
20100069614 | Antibody producing non-human mammals - Described are transgenic, non-human animals comprising a nucleic acid encoding an immunoglobulin light chain, whereby the immunoglobulin light chain is human, human-like, or humanized. The nucleic acid is provided with a means that renders it resistant to DNA rearrangements and/or somatic hypermutations. In one embodiment, the nucleic acid comprises an expression cassette for the expression of a desired molecule in cells during a certain stage of development in cells developing into mature B cells. Further provided is methods for producing an immunoglobulin from the transgenic, non-human animal. | 03-18-2010 |
20100146647 | Antibody producing non-human mammals - Described are transgenic, non-human animals comprising a nucleic acid encoding an immunoglobulin light chain, whereby the immunoglobulin light chain is human, human-like, or humanized. The nucleic acid is provided with a means that renders it resistant to DNA rearrangements and/or somatic hypermutations. In one embodiment, the nucleic acid comprises an expression cassette for the expression of a desired molecule in cells during a certain stage of development in cells developing into mature B cells. Further provided is methods for producing an immunoglobulin from the transgenic, non-human animal. | 06-10-2010 |
20110177073 | Recombinant production of mixtures of antibodies - Provided is methods for producing mixtures of antibodies from a single host cell clone, wherein, a nucleic acid sequence encoding a light chain and nucleic acid sequences encoding different heavy chains are expressed in a recombinant host cell. The recombinantly produced antibodies in the mixtures according to the invention suitably comprise identical light chains paired to different heavy chains capable of pairing to the light chain, thereby forming functional antigen-binding domains. Mixtures of the recombinantly produced antibodies are also provided by the invention. Such mixtures can be used in a variety of fields. | 07-21-2011 |
20120058907 | Mixtures of binding proteins - Described are methods for producing libraries of cells expressing at least two separate single polypeptide chain binding proteins, in which the binding proteins have different target epitopes. Such libraries are made by integration of the nucleic acid sequences encoding the polypeptide chains into the genome of the host cell, and selecting for cells that have successfully integrated these nucleic acids. The selected cells are preferably subjected to a cloning step. Mixtures of binding proteins are produced without having to individually produce each of the components of the mixture. A library of cells wherein essentially each cell encodes at least two single polypeptide chain binding proteins having different target epitopes is also herewith provided, as well as methods for producing a composition comprising at least two separate single polypeptide chain binding proteins having different target epitopes. | 03-08-2012 |
20120177637 | Method for selecting a single cell expressing a heterogeneous combination of antibodies - The present invention provides combinations of specific binding proteins, such as immunoglobulins, that are designed to be true combinations, essentially all components of the combination being functional and compatible with each other. The invention further provides a method for producing a composition comprising at least two different proteinaceous molecules comprising paired variable regions, the at least two proteinaceous molecules having different binding specificities, comprising paired variable regions, at least two proteinaceous molecules having different binding specificities, comprising contacting at least three different variable regions under conditions allowing for pairing of variable regions and harvesting essentially all proteinaceous molecules having binding specificities resulting from the pairing. | 07-12-2012 |
Ton Logtenberg, Driebergen-Rijsenburg NL
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20130096020 | GENERATION OF BINDING MOLECULES - Provided are methods for efficiently and comprehensively screening antibody repertoires from B cells to obtain and produce molecules with binding characteristics and functional activities for use in human therapy. | 04-18-2013 |
Ton Logtenberg, Utrecht NL
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20130145484 | ANTIBODY PRODUCING NON-HUMAN MAMMALS - Described are transgenic, non-human animals comprising a nucleic acid encoding an immunoglobulin light chain, whereby the immunoglobulin light chain is human, human-like, or humanized. The nucleic acid is provided with a means that renders it resistant to DNA rearrangements and/or somatic hypermutations. In one embodiment, the nucleic acid comprises an expression cassette for the expression of a desired molecule in cells during a certain stage of development in cells developing into mature B cells. Further provided is methods for producing an immunoglobulin from the transgenic, non-human animal. | 06-06-2013 |
20130243773 | RECOMBINANT PRODUCTION OF MIXTURES OF ANTIBODIES - Provided is methods for producing mixtures of antibodies from a single host cell clone, wherein, a nucleic acid sequence encoding a light chain and nucleic acid sequences encoding different heavy chains are expressed in a recombinant host cell. The recombinantly produced antibodies in the mixtures according to the invention suitably comprise identical light chains paired to different heavy chains capable of pairing to the light chain, thereby forming functional antigen-binding domains. Mixtures of the recombinantly produced antibodies are also provided by the invention. Such mixtures can be used in a variety of fields. | 09-19-2013 |
20130336981 | METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES - The invention provides means and methods for producing one or more Ig-like molecules in a single host cell. Novel CH3 mutations enabling the production of monospecific and/or bispecific Ig-like molecules of interest are also provided. | 12-19-2013 |
20140072579 | METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES - The invention provides means and methods for producing one or more Ig-like molecules in a single host cell. Novel CH3 mutations enabling the production of monospecific and/or bispecific Ig-like molecules of interest are also provided. | 03-13-2014 |
20140120096 | BISPECIFIC IGG ANTIBODIES AS T CELL ENGAGERS - Bispecific IgG antibodies which bind to CLEC12A and an antigen on an immune effector cell are provided. | 05-01-2014 |
20140140999 | METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES - The invention provides means and methods for producing one or more Ig-like molecules in a single host cell. Novel CH3 mutations enabling the production of monospecific and/or bispecific Ig-like molecules of interest are also provided. | 05-22-2014 |
20140314755 | ANTIBODY PRODUCING NON-HUMAN MAMMALS - Described are transgenic, non-human animals comprising a nucleic acid encoding an immunoglobulin light chain, whereby the immunoglobulin light chain is human, human-like, or humanized. The nucleic acid is provided with a means that renders it resistant to DNA rearrangements and/or somatic hypermutations. In one embodiment, the nucleic acid comprises an expression cassette for the expression of a desired molecule in cells during a certain stage of development in cells developing into mature B cells. Further provided is methods for producing an immunoglobulin from the transgenic, non-human animal. | 10-23-2014 |
20140317766 | ANTIBODY PRODUCING NON-HUMAN MAMMALS - Described are transgenic, non-human animals comprising a nucleic acid encoding an immunoglobulin light chain, whereby the immunoglobulin light chain is human, human-like, or humanized. The nucleic acid is provided with a means that renders it resistant to DNA rearrangements and/or somatic hypermutations. In one embodiment, the nucleic acid comprises an expression cassette for the expression of a desired molecule in cells during a certain stage of development in cells developing into mature B cells. Further provided is methods for producing an immunoglobulin from the transgenic, non-human animal. | 10-23-2014 |
20150139996 | METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES - The invention provides means and methods for producing one or more Ig-like molecules in a single host cell. Novel CH3 mutations enabling the production of monospecific and/or bispecific Ig-like molecules of interest are also provided. | 05-21-2015 |
20150196637 | METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES - The invention provides means and methods for producing one or more Ig-like molecules in a single host cell. Novel CH3 mutations enabling the production of monospecific and/or bispecific Ig-like molecules of interest are also provided. | 07-16-2015 |
Ton Nellissen, Horst NL
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20080205017 | Interconnection and Packaging Method for Biomedical Devices with Electronic and Fluid Functions - An interconnection and packaging method is provided for manufacturing of Lab-on-chip (LOC) and Micro Total Analyses Systems. Different functions, such as biosensors, heaters, coolers, valves, and pumps, are combined in an electronic/mechanical/fluidic module by flip-chip technology using an ultrasound bounding process. A predefined polymeric ring on the chip serves as a seal. | 08-28-2008 |
Ton Peerdeman, Apeldoorn NL
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20110080316 | SURVEILLANCE SYSTEM FOR DETECTING TARGETS WITH HIGH CROSS-RANGE RESOLUTION BETWEEN TARGETS - A surveillance system for detecting targets with high cross-range resolution between targets. The system includes at least two radar antennae mounted on blades of a windmill and is configured to apply a compressive sensing technique when the blades do not rotate. | 04-07-2011 |
20110285581 | Surveillance System Comprising a Radar Antenna Mounted on a Blade of a Windmill - A surveillance system for detecting targets comprises a radar antenna mounted on a blade of a windmill. | 11-24-2011 |
Ton Tesink, Venlo NL
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20110210038 | TRAY, IN PARTICULAR FOR CATERING PURPOSES ONBOARD AIRCRAFTS - A tray, in particular for catering purposes onboard aircrafts, including a tray body defining a receiving surface for receiving thereon items to be carried by use of the tray. The tray body includes an interlocking device for releasably engaging an interlocking device of the tray body of a similar tray, when at least two trays are positioned such that the receiving surfaces of the tray bodies are overlapping each other partially. The interlocking device of the trays interacting such that when one of the trays is drawn in a drawing direction, the other tray is moved along in the drawing direction. | 09-01-2011 |
20130134158 | TRAY, IN PARTICULAR FOR CATERING PURPOSES ONBOARD AIRCRAFTS - A tray, in particular for catering purposes onboard aircrafts, including a tray body defining a receiving surface for receiving thereon items to be carried by use of the tray. The tray body includes an interlocking device for releasably engaging an interlocking device of the tray body of a similar tray, when at least two trays are positioned such that the receiving surfaces of the tray bodies are overlapping each other partially. The interlocking device of the trays interacting such that when one of the trays is drawn in a drawing direction, the other tray is moved along in the drawing direction. | 05-30-2013 |
Ton Verachtert, Shilde BE
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20130088348 | METHODS FOR ENSURING THE SAFETY OF A WHEELCHAIR PASSENGER IN A TRANSPORT VEHICLE - A method for ensuring the safety of a wheelchair passenger in a transport vehicle is disclosed. The method ensures that the wheelchair is blocked from moving by fixating the wheelchair to the vehicle floor and ensures that the wheelchair passenger is secured in his wheelchair by a safety-belt system. Prior to transport the method includes sensing if the wheelchair is correctly fixed to the vehicle floor and sensing if the safety-belt system is applied correctly. In a second aspect, a method for ensuring the safety of a wheelchair passenger in a transport vehicle is provided, by instructing the operator of the securing procedure to be followed. The safety of a wheelchair passenger in a vehicle is ensured by allowing the wheelchair user to indicate his status of safety. | 04-11-2013 |